-
1
-
-
84872967522
-
Cancer statistics, 2013
-
Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J. Clin. 63(1), 11-30 (2013
-
(2013)
CA Cancer J. Clin
, vol.63
, Issue.1
, pp. 11-30
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
67649713132
-
Management of localized prostate cancer in men over 65 years
-
Cooperberg MR, Konety BR. Management of localized prostate cancer in men over 65 years. Curr. Opin. Urol. 19(3), 309-314 (2009
-
(2009)
Curr. Opin. Urol
, vol.19
, Issue.3
, pp. 309-314
-
-
Cooperberg, M.R.1
Konety, B.R.2
-
3
-
-
84880005911
-
Early detection of prostate cancer: AUA guideline
-
Carter HB, Albertsen PC, Barry MJ et al. Early detection of prostate cancer: AUA guideline. J. Urol. 190(2), 419-426 (2013
-
(2013)
J. Urol
, vol.190
, Issue.2
, pp. 419-426
-
-
Carter, H.B.1
Albertsen, P.C.2
Barry, M.J.3
-
4
-
-
84880002079
-
Recent trends in prostate cancer incidence by age, cancer stage, and grade, the United States 2001-2007
-
691380
-
Li J, Djenaba JA, Soman A, Rim SH, Master VA. Recent trends in prostate cancer incidence by age, cancer stage, and grade, the United States, 2001-2007. Prostate Cancer 691380 (2012
-
(2012)
Prostate Cancer
-
-
Li, J.1
Djenaba, J.A.2
Soman, A.3
Rim, S.H.4
Master, V.A.5
-
5
-
-
0034085989
-
Metastatic patterns of prostate cancer: An autopsy study of 1,589 patients
-
Bubendorf L, Schopfer A, Wagner U et al. Metastatic patterns of prostate cancer: An autopsy study of 1,589 patients. Hum. Pathol. 31(5), 578-583 (2000
-
(2000)
Hum. Pathol
, vol.31
, Issue.5
, pp. 578-583
-
-
Bubendorf, L.1
Schopfer, A.2
Wagner, U.3
-
6
-
-
0003998061
-
-
Lippincott, Williams and Wilkins, PA, USA
-
Devita VT, Rosenberg SA, Hellman S. Cancer: Principles and Practice of Oncology (7th). Lippincott, Williams and Wilkins, PA, USA (2005
-
(2005)
Cancer: Principles and Practice of Oncology (7th
-
-
Devita, V.T.1
Rosenberg, S.A.2
Hellman, S.3
-
7
-
-
0036716282
-
Strategies for MMP inhibition in cancer: Innovations for the post-Trial era
-
Overall CM, Lopez-Otin C. Strategies for MMP inhibition in cancer: Innovations for the post-Trial era. Nat. Rev. Cancer 2(9), 657-672 (2002
-
(2002)
Nat. Rev. Cancer
, vol.2
, Issue.9
, pp. 657-672
-
-
Overall, C.M.1
Lopez-Otin, C.2
-
8
-
-
84879232768
-
Prostate cancer overdiagnosis and overtreatment
-
Klotz L. Prostate cancer overdiagnosis and overtreatment. Curr. Opin. Endocrinol. Diabetes Obes. 20(3), 204-209 (2013
-
(2013)
Curr. Opin. Endocrinol. Diabetes Obes
, vol.20
, Issue.3
, pp. 204-209
-
-
Klotz, L.1
-
9
-
-
0037460786
-
Early prostate cancer: Clinical decision-making
-
Jani AB, Hellman S. Early prostate cancer: Clinical decision-making. Lancet 361(9362), 1045-1053 (2003
-
(2003)
Lancet
, vol.361
, Issue.9362
, pp. 1045-1053
-
-
Jani, A.B.1
Hellman, S.2
-
10
-
-
35148817305
-
Androgen deprivation therapy in the treatment of advanced prostate cancer
-
Perlmutter MA, Lepor H. Androgen deprivation therapy in the treatment of advanced prostate cancer. Rev. Urol. 9(Suppl. 1), S3-S8 (2007
-
(2007)
Rev. Urol
, vol.9
, Issue.SUPPL. 1
-
-
Perlmutter, M.A.1
Lepor, H.2
-
11
-
-
84873713208
-
Novel therapies for the treatment of advanced prostate cancer
-
Clarke JM, Armstrong AJ. Novel therapies for the treatment of advanced prostate cancer. Curr. Treat. Options Oncol. 14(1), 109-126 (2013
-
(2013)
Curr. Treat. Options Oncol
, vol.14
, Issue.1
, pp. 109-126
-
-
Clarke, J.M.1
Armstrong, A.J.2
-
12
-
-
84881403991
-
A road map to comprehensive androgen receptor axis targeting for castration-resistant prostate cancer
-
Mitsiades N. A road map to comprehensive androgen receptor axis targeting for castration-resistant prostate cancer. Cancer Res. 73(15), 4599-4605 (2013
-
(2013)
Cancer Res
, vol.73
, Issue.15
, pp. 4599-4605
-
-
Mitsiades, N.1
-
13
-
-
79953320228
-
New strategies in metastatic prostate cancer: Targeting the androgen receptor signaling pathway
-
Attard G, Richards J, De Bono JS. New strategies in metastatic prostate cancer: Targeting the androgen receptor signaling pathway. Clin. Cancer Res. 17(7), 1649-1657 (2011
-
(2011)
Clin. Cancer Res
, vol.17
, Issue.7
, pp. 1649-1657
-
-
Attard, G.1
Richards, J.2
De Bono, J.S.3
-
14
-
-
0037812658
-
The influence of finasteride on the development of prostate cancer
-
Thompson IM, Goodman PJ, Tangen CM et al. The influence of finasteride on the development of prostate cancer. N. Engl. J. Med. 349(3), 215-224 (2003
-
(2003)
N. Engl. J. Med
, vol.349
, Issue.3
, pp. 215-224
-
-
Thompson, I.M.1
Goodman, P.J.2
Tangen, C.M.3
-
15
-
-
0025974356
-
Carcinoma of the prostate
-
Gittes RF. Carcinoma of the prostate. N. Engl. J. Med. 324(4), 236-245 (1991
-
(1991)
N. Engl. J. Med
, vol.324
, Issue.4
, pp. 236-245
-
-
Gittes, R.F.1
-
16
-
-
80054686286
-
Tumor metastasis: Molecular insights and evolving paradigms
-
Valastyan S, Weinberg RA. Tumor metastasis: Molecular insights and evolving paradigms. Cell 147(2), 275-292 (2011
-
(2011)
Cell
, vol.147
, Issue.2
, pp. 275-292
-
-
Valastyan, S.1
Weinberg, R.A.2
-
17
-
-
0018608109
-
Some characteristics of metastasis in man
-
Sugarbaker EV. Some characteristics of metastasis in man. Am. J. Pathol. 97(3), 623-632 (1979
-
(1979)
Am. J. Pathol
, vol.97
, Issue.3
, pp. 623-632
-
-
Sugarbaker, E.V.1
-
18
-
-
33846931501
-
The metastatic cascade in prostate cancer
-
Arya M, Bott SR, Shergill IS, Ahmed HU, Williamson M, Patel HR. The metastatic cascade in prostate cancer. Surg. Oncol. 15(3), 117-128 (2006
-
(2006)
Surg. Oncol
, vol.15
, Issue.3
, pp. 117-128
-
-
Arya, M.1
Bott, S.R.2
Shergill, I.S.3
Ahmed, H.U.4
Williamson, M.5
Patel, H.R.6
-
19
-
-
84891111855
-
Strategies to increase drug penetration in solid tumors
-
Choi IK, Strauss R, Richter M, Yun CO, Lieber A. Strategies to increase drug penetration in solid tumors. Front. Oncol. 3, 193 (2013
-
Front. Oncol
, vol.3
, Issue.193
, pp. 2013
-
-
Choi, I.K.1
Strauss, R.2
Richter, M.3
Yun, C.O.4
Lieber, A.5
-
20
-
-
0030018285
-
Prospective origins of prostate carcinoma. Prostatic intraepithelial neoplasia and atypical adenomatous hyperplasia
-
Bostwick DG. Prospective origins of prostate carcinoma. Prostatic intraepithelial neoplasia and atypical adenomatous hyperplasia. Cancer 78(2), 330-336 (1996
-
(1996)
Cancer
, vol.78
, Issue.2
, pp. 330-336
-
-
Bostwick, D.G.1
-
21
-
-
27144552692
-
Cell migration/invasion assays and their application in cancer drug discovery
-
Eccles SA, Box C, Court W. Cell migration/invasion assays and their application in cancer drug discovery. Biotechnol. Annu. Rev. 11, 391-421 (2005
-
(2005)
Biotechnol. Annu. Rev
, vol.11
, pp. 391-421
-
-
Eccles, S.A.1
Box, C.2
Court, W.3
-
22
-
-
35548932457
-
Structure and mechanism of cadherins and catenins in cell-cell contacts
-
Pokutta S, Weis WI. Structure and mechanism of cadherins and catenins in cell-cell contacts. Annu. Rev. Cell. Dev. Biol. 23, 237-261 (2007
-
(2007)
Annu. Rev. Cell. Dev. Biol
, vol.23
, pp. 237-261
-
-
Pokutta, S.1
Weis, W.I.2
-
23
-
-
0033379264
-
Cell adhesion molecules: Selectins and integrins
-
Gonzalez-Amaro R, Sanchez-Madrid F. Cell adhesion molecules: Selectins and integrins. Crit. Rev. Immunol. 19(5-6), 389-429 (1999
-
(1999)
Crit. Rev. Immunol
, vol.19
, Issue.5-6
, pp. 389-429
-
-
Gonzalez-Amaro, R.1
Sanchez-Madrid, F.2
-
24
-
-
84893199966
-
Integrins in prostate cancer invasion and metastasis
-
Hamilton DG (Ed.). InTech, London, UK
-
Suyin PC, Dickinson JL, Holloway AF. Integrins in Prostate Cancer Invasion and Metastasis. In:Advances in Prostate Cancer . Hamilton DG (Ed.). InTech, London, UK (2013
-
(2013)
Advances in Prostate Cancer
-
-
Suyin, P.C.1
Dickinson, J.L.2
Holloway, A.F.3
-
25
-
-
79960150078
-
Differences in integrin expression and signaling within human breast cancer cells
-
Taherian A, Li X, Liu Y, Haas TA. Differences in integrin expression and signaling within human breast cancer cells. BMC Cancer 11, 293 (2011
-
BMC Cancer
, vol.11
, Issue.293
, pp. 2011
-
-
Taherian, A.1
Li, X.2
Liu, Y.3
Haas, T.A.4
-
26
-
-
77952925797
-
Involvement of the cytoskeleton in controlling leading-edge function during chemotaxis
-
Lee S, Shen Z, Robinson DN, Briggs S, Firtel RA. Involvement of the cytoskeleton in controlling leading-edge function during chemotaxis. Mol. Biol. Cell 21(11), 1810-1824 (2010
-
(2010)
Mol. Biol. Cell
, vol.21
, Issue.11
, pp. 1810-1824
-
-
Lee, S.1
Shen, Z.2
Robinson, D.N.3
Briggs, S.4
Firtel, R.A.5
-
27
-
-
0033938994
-
Recurring views on the structure and function of the cytoskeleton: A 300-year epic
-
Frixione E. Recurring views on the structure and function of the cytoskeleton: A 300-year epic. Cell Motil. Cytoskeleton 46(2), 73-94 (2000
-
(2000)
Cell Motil. Cytoskeleton
, vol.46
, Issue.2
, pp. 73-94
-
-
Frixione, E.1
-
28
-
-
54249128761
-
Regulation of angiogenesis: Apoptotic cues from the ECM
-
Cheresh DA, Stupack DG. Regulation of angiogenesis: Apoptotic cues from the ECM. Oncogene 27(48), 6285-6298 (2008
-
(2008)
Oncogene
, vol.27
, Issue.48
, pp. 6285-6298
-
-
Cheresh, D.A.1
Stupack, D.G.2
-
29
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2(3), 161-174 (2002
-
(2002)
Nat. Rev. Cancer
, vol.2
, Issue.3
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
30
-
-
33847683870
-
Regulation of matrix metalloproteinase gene expression
-
Yan C, Boyd DD. Regulation of matrix metalloproteinase gene expression. J. Cell Physiol. 211(1), 19-26 (2007
-
(2007)
J. Cell Physiol
, vol.211
, Issue.1
, pp. 19-26
-
-
Yan, C.1
Boyd, D.D.2
-
31
-
-
0034615550
-
Tissue inhibitors of metalloproteinases: Evolution, structure and function
-
Brew K, Dinakarpandian D, Nagase H. Tissue inhibitors of metalloproteinases: Evolution, structure and function. Biochim. Biophys. Acta 1477(1-2), 267-283 (2000
-
(2000)
Biochim. Biophys. Acta
, vol.1477
, Issue.1-2
, pp. 267-283
-
-
Brew, K.1
Dinakarpandian, D.2
Nagase, H.3
-
32
-
-
0031787039
-
FGF-1: A human growth factor in the induction of neoangiogenesis
-
Stegmann TJ. FGF-1: A human growth factor in the induction of neoangiogenesis. Expert Opin. Investig. Drugs 7(12), 2011-2015 (1998
-
(1998)
Expert Opin. Investig. Drugs
, vol.7
, Issue.12
, pp. 2011-2015
-
-
Stegmann, T.J.1
-
33
-
-
10644279947
-
Vascular endothelial growth factor and angiogenesis
-
Hoeben A, Landuyt B, Highley MS, Wildiers H, van Oosterom AT, de Bruijn EA. Vascular endothelial growth factor and angiogenesis. Pharmacol. Rev. 56(4), 549-580 (2004
-
(2004)
Pharmacol. Rev
, vol.56
, Issue.4
, pp. 549-580
-
-
Hoeben, A.1
Landuyt, B.2
Highley, M.S.3
Wildiers, H.4
Van Oosterom, A.T.5
De Bruijn, E.A.6
-
34
-
-
0037316605
-
Matrix metalloproteinases angiogenesis and cancer: Commentary re: AC Lockhart et al. Reduction of wound angiogenesis in patients treated with BMS-275291 a broad spectrum matrix metalloproteinase inhibitor
-
Rundhaug JE. Matrix metalloproteinases, angiogenesis, and cancer: Commentary re: AC Lockhart et al. Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor. Clin. Cancer Res. 9(2), 551-554 (2003
-
(2003)
Clin. Cancer Res
, vol.9
, Issue.2
, pp. 551-554
-
-
Rundhaug, J.E.1
-
35
-
-
0033119833
-
Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function
-
Grunstein J, Roberts WG, Mathieu-Costello O, Hanahan D, Johnson RS. Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function. Cancer Res. 59(7), 1592-1598 (1999
-
(1999)
Cancer Res
, vol.59
, Issue.7
, pp. 1592-1598
-
-
Grunstein, J.1
Roberts, W.G.2
Mathieu-Costello, O.3
Hanahan, D.4
Johnson, R.S.5
-
36
-
-
79960448516
-
Disseminated and circulating tumor cells for monitoring chemotherapy in urological tumors
-
Kruck S, Gakis G, Stenzl A. Disseminated and circulating tumor cells for monitoring chemotherapy in urological tumors. Anticancer Res. 31(6), 2053-2057 (2011
-
(2011)
Anticancer Res
, vol.31
, Issue.6
, pp. 2053-2057
-
-
Kruck, S.1
Gakis, G.2
Stenzl, A.3
-
37
-
-
77954624770
-
Significance of circulating tumor cells detected by the cellsearch system in patients with metastatic breast colorectal and prostate cancer
-
617421
-
Miller MC, Doyle GV, Terstappen LW. Significance of circulating tumor cells detected by the cellsearch system in patients with metastatic breast colorectal and prostate cancer. J. Oncol. 617421 (2010
-
(2010)
J. Oncol
-
-
Miller, M.C.1
Doyle, G.V.2
Terstappen, L.W.3
-
38
-
-
0023770128
-
Cancer metastasis: Tumor cell and host organ properties important in metastasis to specific secondary sites
-
Nicolson GL. Cancer metastasis: Tumor cell and host organ properties important in metastasis to specific secondary sites. Biochim. Biophys. Acta. 948(2), 175-224 (1988
-
(1988)
Biochim. Biophys. Acta
, vol.948
, Issue.2
, pp. 175-224
-
-
Nicolson, G.L.1
-
39
-
-
84857156986
-
Impact of the SRC inhibitor dasatinib on the metastatic phenotype of human prostate cancer cells
-
Rice L, Lepler S, Pampo C, Siemann DW. Impact of the SRC inhibitor dasatinib on the metastatic phenotype of human prostate cancer cells. Clin. Exp. Metastasis 29(2), 133-142 (2012
-
(2012)
Clin. Exp. Metastasis
, vol.29
, Issue.2
, pp. 133-142
-
-
Rice, L.1
Lepler, S.2
Pampo, C.3
Siemann, D.W.4
-
40
-
-
66149164441
-
SRC family kinase activity is up-regulated in hormone-refractory prostate cancer
-
Tatarov O, Mitchell TJ, Seywright M, Leung HY, Brunton VG, Edwards J. SRC family kinase activity is up-regulated in hormone-refractory prostate cancer. Clin. Cancer Res. 15(10), 3540-3549 (2009
-
(2009)
Clin. Cancer Res
, vol.15
, Issue.10
, pp. 3540-3549
-
-
Tatarov, O.1
Mitchell, T.J.2
Seywright, M.3
Leung, H.Y.4
Brunton, V.G.5
Edwards, J.6
-
41
-
-
44849134528
-
Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model
-
Park SI, Zhang J, Phillips KA et al. Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model. Cancer Res. 68(9), 3323-3333 (2008
-
(2008)
Cancer Res
, vol.68
, Issue.9
, pp. 3323-3333
-
-
Park, S.I.1
Zhang, J.2
Phillips, K.A.3
-
42
-
-
33749445413
-
Regulation of androgen receptor activity by tyrosine phosphorylation
-
Guo Z, Dai B, Jiang T et al. Regulation of androgen receptor activity by tyrosine phosphorylation. Cancer Cell 10(4), 309-319 (2006
-
(2006)
Cancer Cell
, vol.10
, Issue.4
, pp. 309-319
-
-
Guo, Z.1
Dai, B.2
Jiang, T.3
-
43
-
-
73149115110
-
Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer
-
Yu EY, Wilding G, Posadas E et al. Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer. Clin. Cancer Res. 15(23), 7421-7428 (2009
-
(2009)
Clin. Cancer Res
, vol.15
, Issue.23
, pp. 7421-7428
-
-
Yu, E.Y.1
Wilding, G.2
Posadas, E.3
-
44
-
-
83855162892
-
Dasatinib combined with docetaxel for castration-resistant prostate cancer: Results from a Phase 1-2 study
-
Araujo JC, Mathew P, Armstrong AJ et al. Dasatinib combined with docetaxel for castration-resistant prostate cancer: Results from a Phase 1-2 study. Cancer 118(1), 63-71 (2012
-
(2012)
Cancer
, vol.118
, Issue.1
, pp. 63-71
-
-
Araujo, J.C.1
Mathew, P.2
Armstrong, A.J.3
-
45
-
-
84879957661
-
A Phase II trial of dasatinib in patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy
-
Twardowski PW, Beumer JH, Chen CS et al. A Phase II trial of dasatinib in patients with metastatic castration-resistant prostate cancer treated previously with chemotherapy. Anticancer Drugs 24(7), 743-753 (2013
-
(2013)
Anticancer Drugs
, vol.24
, Issue.7
, pp. 743-753
-
-
Twardowski, P.W.1
Beumer, J.H.2
Chen, C.S.3
-
46
-
-
84875096268
-
Long-Term use of dasatinib in patients with metastatic castration-resistant prostate cancer after receiving the combination of dasatinib and docetaxel
-
Araujo JC, Trudel GC, Paliwal P. Long-Term use of dasatinib in patients with metastatic castration-resistant prostate cancer after receiving the combination of dasatinib and docetaxel. Cancer Manag. Res. 6, 25-30 (2013
-
(2013)
Cancer Manag. Res
, vol.6
, pp. 25-30
-
-
Araujo, J.C.1
Trudel, G.C.2
Paliwal, P.3
-
47
-
-
84881506626
-
Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors
-
Breen MJ, Moran DM, Liu W, Huang X, Vary CP, Bergan RC. Endoglin-mediated suppression of prostate cancer invasion is regulated by activin and bone morphogenetic protein type II receptors. PLoS ONE 8(8), e72407 (2013
-
(2013)
PLoS ONE
, vol.8
, Issue.8
-
-
Breen, M.J.1
Moran, D.M.2
Liu, W.3
Huang, X.4
Vary, C.P.5
Bergan, R.C.6
-
49
-
-
72049091524
-
Targeting the transforming growth factor-b signaling pathway in human cancer
-
Nagaraj NS, Datta PK. Targeting the transforming growth factor-b signaling pathway in human cancer. Expert Opin. Investig. Drugs 19(1), 77-91 (2010
-
(2010)
Expert Opin. Investig. Drugs
, vol.19
, Issue.1
, pp. 77-91
-
-
Nagaraj, N.S.1
Datta, P.K.2
-
50
-
-
33748059537
-
Transforming growth factor-b promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells
-
Ao M, Williams K, Bhowmick NA, Hayward SW. Transforming growth factor-b promotes invasion in tumorigenic but not in nontumorigenic human prostatic epithelial cells. Cancer Res. 66(16), 8007-8016 (2006
-
(2006)
Cancer Res
, vol.66
, Issue.16
, pp. 8007-8016
-
-
Ao, M.1
Williams, K.2
Bhowmick, N.A.3
Hayward, S.W.4
-
51
-
-
33746763680
-
TGF-b in cancer and as a therapeutic target
-
Pinkas J, Teicher BA. TGF-b in cancer and as a therapeutic target. Biochem. Pharmacol. 72(5), 523-529 (2006
-
(2006)
Biochem. Pharmacol
, vol.72
, Issue.5
, pp. 523-529
-
-
Pinkas, J.1
Teicher, B.A.2
-
52
-
-
0037380050
-
TGF-b-l/Smad signaling in prostate cancer
-
Bello-Deocampo D, Tindall DJ. TGF-b-l/Smad signaling in prostate cancer. Curr. Drug Targets 4(3), 197-207 (2003
-
(2003)
Curr. Drug Targets
, vol.4
, Issue.3
, pp. 197-207
-
-
Bello-Deocampo, D.1
Tindall, D.J.2
-
53
-
-
16344378397
-
TGF-b and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition
-
Valcourt U, Kowanetz M, Niimi H, Heldin CH, Moustakas A. TGF-b and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition. Mol. Biol. Cell. 16(4), 1987-2002 (2005
-
(2005)
Mol. Biol. Cell
, vol.16
, Issue.4
, pp. 1987-2002
-
-
Valcourt, U.1
Kowanetz, M.2
Niimi, H.3
Heldin, C.H.4
Moustakas, A.5
-
54
-
-
1542574202
-
Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance
-
Holzbeierlein J, Lal P, Latulippe E et al. Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance. Am. J. Pathol. 164(1), 217-227 (2004
-
(2004)
Am. J. Pathol
, vol.164
, Issue.1
, pp. 217-227
-
-
Holzbeierlein, J.1
Lal, P.2
Latulippe, E.3
-
55
-
-
36048973196
-
Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway
-
Craft CS, Romero D, Vary CP, Bergan RC. Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway. Oncogene 26(51), 7240-7250 (2007
-
(2007)
Oncogene
, vol.26
, Issue.51
, pp. 7240-7250
-
-
Craft, C.S.1
Romero, D.2
Vary, C.P.3
Bergan, R.C.4
-
57
-
-
77950911663
-
Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration
-
Romero D, Terzic A, Conley BA et al. Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration. Carcinogenesis 31(3), 359-366 (2010
-
(2010)
Carcinogenesis
, vol.31
, Issue.3
, pp. 359-366
-
-
Romero, D.1
Terzic, A.2
Conley, B.A.3
-
58
-
-
34547187636
-
Inhibition of TGF-b2 with AP 12009 in recurrent malignant gliomas: From preclinical to Phase I/II studies
-
Hau P, Jachimczak P, Schlingensiepen R et al. Inhibition of TGF-b2 with AP 12009 in recurrent malignant gliomas: From preclinical to Phase I/II studies. Oligonucleotides 17(2), 201-212 (2007
-
(2007)
Oligonucleotides
, vol.17
, Issue.2
, pp. 201-212
-
-
Hau, P.1
Jachimczak, P.2
Schlingensiepen, R.3
-
60
-
-
79951602633
-
Targeted therapy for high-grade glioma with the TGF-b2 inhibitor trabedersen: Results of a randomized and controlled Phase IIb study
-
Bogdahn U, Hau P, Stockhammer G et al. Targeted therapy for high-grade glioma with the TGF-b2 inhibitor trabedersen: Results of a randomized and controlled Phase IIb study. Neuro. Oncol. 13(1), 132-142 (2011
-
(2011)
Neuro. Oncol
, vol.13
, Issue.1
, pp. 132-142
-
-
Bogdahn, U.1
Hau, P.2
Stockhammer, G.3
-
61
-
-
38449103630
-
Antisense therapeutics for tumor treatment: The TGF-b2 inhibitor AP 12009 in clinical development against malignant tumors
-
Schlingensiepen KH, Fischer-Blass B, Schmaus S, Ludwig S. Antisense therapeutics for tumor treatment: The TGF-b2 inhibitor AP 12009 in clinical development against malignant tumors. Recent Results Cancer Res. 177, 137-150 (2008
-
(2008)
Recent Results Cancer Res
, vol.177
, pp. 137-150
-
-
Schlingensiepen, K.H.1
Fischer-Blass, B.2
Schmaus, S.3
Ludwig, S.4
-
62
-
-
0036086409
-
Blockade of TGF-b inhibits mammary tumor cell viability, migration, and metastases
-
Muraoka RS, Dumont N, Ritter CA et al. Blockade of TGF-b inhibits mammary tumor cell viability, migration, and metastases. J. Clin. Invest. 109(12), 1551-1559 (2002
-
(2002)
J. Clin. Invest
, vol.109
, Issue.12
, pp. 1551-1559
-
-
Muraoka, R.S.1
Dumont, N.2
Ritter, C.A.3
-
63
-
-
84856977508
-
Effect of transforming growth factor b (TGF-b) receptor I kinase inhibitor on prostate cancer bone growth
-
Wan X, Li ZG, Yingling JM et al. Effect of transforming growth factor b (TGF-b) receptor I kinase inhibitor on prostate cancer bone growth. Bone 50(3), 695-703 (2012
-
(2012)
Bone
, vol.50
, Issue.3
, pp. 695-703
-
-
Wan, X.1
Li, Z.G.2
Yingling, J.M.3
-
64
-
-
43949140575
-
Blocking transforming growth factor-b up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells
-
Fransvea E, Angelotti U, Antonaci S, Giannelli G. Blocking transforming growth factor-b up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells. Hepatology 47(5), 1557-1566 (2008
-
(2008)
Hepatology
, vol.47
, Issue.5
, pp. 1557-1566
-
-
Fransvea, E.1
Angelotti, U.2
Antonaci, S.3
Giannelli, G.4
-
65
-
-
42249099019
-
LY2109761, a novel transforming growth factor b receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis
-
Melisi D, Ishiyama S, Sclabas GM et al. LY2109761, a novel transforming growth factor b receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis. Mol. Cancer Ther. 7(4), 829-840 (2008
-
(2008)
Mol. Cancer Ther
, vol.7
, Issue.4
, pp. 829-840
-
-
Melisi, D.1
Ishiyama, S.2
Sclabas, G.M.3
-
66
-
-
82655181475
-
Blockade of TGF-b signaling by the TGFbR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma
-
Zhang M, Kleber S, Rohrich M et al. Blockade of TGF-b signaling by the TGFbR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma. Cancer Res. 71(23), 7155-7167 (2011
-
(2011)
Cancer Res
, vol.71
, Issue.23
, pp. 7155-7167
-
-
Zhang, M.1
Kleber, S.2
Rohrich, M.3
-
67
-
-
33748305561
-
Inhibition of transforming growth factor-b1-induced signaling and epithelial-To-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA
-
Zhao BM, Hoffmann FM. Inhibition of transforming growth factor-b1-induced signaling and epithelial-To-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA. Mol. Biol. Cell 17(9), 3819-3831 (2006
-
(2006)
Mol. Biol. Cell
, vol.17
, Issue.9
, pp. 3819-3831
-
-
Zhao, B.M.1
Hoffmann, F.M.2
-
68
-
-
0034212136
-
Mitogen-Activated protein kinase kinase 4 (MKK4)
-
Cuenda A. Mitogen-Activated protein kinase kinase 4 (MKK4). Int. J. Biochem. Cell. Biol. 32(6), 581-587 (2000
-
(2000)
Int. J. Biochem. Cell. Biol
, vol.32
, Issue.6
, pp. 581-587
-
-
Cuenda, A.1
-
69
-
-
0027404982
-
Type IV collagenase (M(r) 72,000) expression in human prostate. Benign and malignant tissue
-
Stearns ME, Wang M. Type IV collagenase (M(r) 72,000) expression in human prostate. benign and malignant tissue. Cancer Res. 53(4), 878-883 (1993
-
(1993)
Cancer Res
, vol.53
, Issue.4
, pp. 878-883
-
-
Stearns, M.E.1
Wang, M.2
-
70
-
-
69249083967
-
MEK4 function, genistein treatment, and invasion of human prostate cancer cells
-
Xu L, Ding Y, Catalona WJ et al. MEK4 function, genistein treatment, and invasion of human prostate cancer cells. J. Natl Cancer Inst. 101(16), 1141-1155 (2009
-
(2009)
J. Natl Cancer Inst
, vol.101
, Issue.16
, pp. 1141-1155
-
-
Xu, L.1
Ding, Y.2
Catalona, W.J.3
-
71
-
-
17144426480
-
Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells
-
Huang X, Chen S, Xu L et al. Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells. Cancer Res. 65(8), 3470-3478 (2005
-
(2005)
Cancer Res
, vol.65
, Issue.8
, pp. 3470-3478
-
-
Huang, X.1
Chen, S.2
Xu, L.3
-
72
-
-
10744226314
-
Phase I pharmacokinetic and pharmacodynamic analysis of unconjugated soy isoflavones administered to individuals with cancer
-
Pt1
-
Takimoto CH, Glover K, Huang X et al. Phase I pharmacokinetic and pharmacodynamic analysis of unconjugated soy isoflavones administered to individuals with cancer. Cancer Epidemiol. Biomarkers Prev. 12(11 Pt 1), 1213-1221 (2003
-
(2003)
Cancer Epidemiol. Biomarkers Prev
, vol.12
, Issue.11
, pp. 1213-1221
-
-
Takimoto, C.H.1
Glover, K.2
Huang, X.3
-
73
-
-
77956896283
-
Crystal structures of MKK4 kinase domain reveal that substrate peptide binds to an allosteric site and induces an auto-inhibition state
-
Matsumoto T, Kinoshita T, Kirii Y, Yokota K, Hamada K, Tada T. Crystal structures of MKK4 kinase domain reveal that substrate peptide binds to an allosteric site and induces an auto-inhibition state. Biochem. Biophys. Res. Commun. 400(3), 369-373 (2010
-
(2010)
Biochem. Biophys. Res. Commun
, vol.400
, Issue.3
, pp. 369-373
-
-
Matsumoto, T.1
Kinoshita, T.2
Kirii, Y.3
Yokota, K.4
Hamada, K.5
Tada, T.6
-
74
-
-
84874777853
-
Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor
-
Kim KB, Kefford R, Pavlick AC et al. Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor. J. Clin. Oncol. 31(4), 482-489 (2013
-
(2013)
J. Clin. Oncol
, vol.31
, Issue.4
, pp. 482-489
-
-
Kim, K.B.1
Kefford, R.2
Pavlick, A.C.3
-
75
-
-
84891938336
-
A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated kinase kinase 4
-
Krishna SN, Luan C-H, Mishra RK et al. A fluorescence-based thermal shift assay identifies inhibitors of mitogen activated kinase kinase 4. PLoS ONE 8(12), e81504 (2013
-
(2013)
PLoS ONE
, vol.8
, Issue.12
-
-
Krishna, S.N.1
Luan, C.-H.2
Mishra, R.K.3
-
76
-
-
57749090308
-
Integrin a(v)b(3)-Targeted cancer therapy
-
Liu Z, Wang F, Chen X. Integrin a(v)b(3)-Targeted cancer therapy. Drug Dev. Res. 69(6), 329-339 (2008
-
(2008)
Drug Dev. Res
, vol.69
, Issue.6
, pp. 329-339
-
-
Liu, Z.1
Wang, F.2
Chen, X.3
-
77
-
-
34548680519
-
Prostate cancer specific integrin avb3 modulates bone metastatic growth and tissue remodeling
-
Mccabe NP, De S, Vasanji A, Brainard J, Byzova TV. Prostate cancer specific integrin avb3 modulates bone metastatic growth and tissue remodeling. Oncogene 26(42), 6238-6243 (2007
-
(2007)
Oncogene
, vol.26
, Issue.42
, pp. 6238-6243
-
-
Mccabe, N.P.1
De S Vasanji, A.2
Brainard, J.3
Byzova, T.V.4
-
78
-
-
0035850669
-
Crystal structure of the extracellular segment of integrin a Vb3
-
Xiong JP, Stehle T, Diefenbach B et al. Crystal structure of the extracellular segment of integrin a Vb3. Science 294(5541), 339-345 (2001
-
(2001)
Science
, vol.294
, Issue.5541
, pp. 339-345
-
-
Xiong, J.P.1
Stehle, T.2
Diefenbach, B.3
-
79
-
-
38149098569
-
Phase I and pharmacokinetic study of etaracizumab (Abegrin), a humanized monoclonal antibody against avb3 integrin receptor, in patients with advanced solid tumors
-
Delbaldo C, Raymond E, Vera K et al. Phase I and pharmacokinetic study of etaracizumab (Abegrin), a humanized monoclonal antibody against avb3 integrin receptor, in patients with advanced solid tumors. Invest. New Drugs 26(1), 35-43 (2008
-
(2008)
Invest. New Drugs
, vol.26
, Issue.1
, pp. 35-43
-
-
Delbaldo, C.1
Raymond, E.2
Vera, K.3
-
80
-
-
27744563296
-
Phase I trial of a monoclonal antibody specific for avb3 integrin (MEDI-522) in patients with advanced malignancies, including an assessment of effect on tumor perfusion
-
Mcneel DG, Eickhoff J, Lee FT et al. Phase I trial of a monoclonal antibody specific for avb3 integrin (MEDI-522) in patients with advanced malignancies, including an assessment of effect on tumor perfusion. Clin. Cancer Res. 11(21), 7851-7860 (2005
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.21
, pp. 7851-7860
-
-
Mcneel, D.G.1
Eickhoff, J.2
Lee, F.T.3
-
81
-
-
77949394260
-
A randomized Phase 2 study of etaracizumab, a monoclonal antibody against integrin a(v)b(3), + or - dacarbazine in patients with stage IV metastatic melanoma
-
Hersey P, Sosman J, O'day S et al. A randomized Phase 2 study of etaracizumab, a monoclonal antibody against integrin a(v)b(3), + or - dacarbazine in patients with stage IV metastatic melanoma. Cancer 116(6), 1526-1534 (2010
-
(2010)
Cancer
, vol.116
, Issue.6
, pp. 1526-1534
-
-
Hersey, P.1
Sosman, J.2
O'day, S.3
-
83
-
-
33947306264
-
Drug evaluation: Volociximab, an angiogenesis-inhibiting chimeric monoclonal antibody
-
Kuwada SK. Drug evaluation: Volociximab, an angiogenesis-inhibiting chimeric monoclonal antibody. Curr. Opin. Mol. Ther. 9(1), 92-98 (2007
-
(2007)
Curr. Opin. Mol. Ther
, vol.9
, Issue.1
, pp. 92-98
-
-
Kuwada, S.K.1
-
84
-
-
33749349945
-
Preclinical evaluation of an anti-A5b1 integrin antibody as a novel anti-Angiogenic agent
-
Ramakrishnan V, Bhaskar V, Law DA et al. Preclinical evaluation of an anti-A5b1 integrin antibody as a novel anti-Angiogenic agent. J. Exp. Ther. Oncol. 5(4), 273-286 (2006
-
(2006)
J. Exp. Ther. Oncol
, vol.5
, Issue.4
, pp. 273-286
-
-
Ramakrishnan, V.1
Bhaskar, V.2
Law, D.A.3
-
85
-
-
59449094255
-
Volociximab, a chimeric monoclonal antibody that specifically binds a5b1 integrin: A Phase I, pharmacokinetic, and biological correlative study
-
Ricart AD, Tolcher AW, Liu G et al. Volociximab, a chimeric monoclonal antibody that specifically binds a5b1 integrin: A Phase I, pharmacokinetic, and biological correlative study. Clin. Cancer Res. 14(23), 7924-7929 (2008
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.23
, pp. 7924-7929
-
-
Ricart, A.D.1
Tolcher, A.W.2
Liu, G.3
-
86
-
-
33749577839
-
A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo
-
Khalili P, Arakelian A, Chen G et al. A non-RGD-based integrin binding peptide (ATN-161) blocks breast cancer growth and metastasis in vivo. Mol. Cancer Ther. 5(9), 2271-2280 (2006
-
(2006)
Mol. Cancer Ther
, vol.5
, Issue.9
, pp. 2271-2280
-
-
Khalili, P.1
Arakelian, A.2
Chen, G.3
-
87
-
-
2442488748
-
CNTO 95, a fully human monoclonal antibody that inhibits av integrins, has antitumor and antiangiogenic activity in vivo
-
Trikha M, Zhou Z, Nemeth JA et al. CNTO 95, a fully human monoclonal antibody that inhibits av integrins, has antitumor and antiangiogenic activity in vivo. Int. J. Cancer 110(3), 326-335 (2004
-
(2004)
Int. J. Cancer
, vol.110
, Issue.3
, pp. 326-335
-
-
Trikha, M.1
Zhou, Z.2
Nemeth, J.A.3
-
88
-
-
84873843972
-
A randomized, double-blind, multicenter, Phase II study of a human monoclonal antibody to human anu integrins (intetumumab) in combination with docetaxel and prednisone for the first-line treatment of patients with metastatic castration-resistant prostate cancer
-
Heidenreich A, Rawal SK, Szkarlat K et al. A randomized, double-blind, multicenter, Phase II study of a human monoclonal antibody to human anu integrins (intetumumab) in combination with docetaxel and prednisone for the first-line treatment of patients with metastatic castration-resistant prostate cancer. Ann. Oncol. 24(2), 329-336 (2013
-
(2013)
Ann. Oncol
, vol.24
, Issue.2
, pp. 329-336
-
-
Heidenreich, A.1
Rawal, S.K.2
Szkarlat, K.3
-
89
-
-
3242754494
-
Emerging views of integrin signaling: Implications for prostate cancer
-
Slack-Davis JK, Parsons JT. Emerging views of integrin signaling: Implications for prostate cancer. J. Cell Biochem. 91(1), 41-46 (2004
-
(2004)
J. Cell Biochem
, vol.91
, Issue.1
, pp. 41-46
-
-
Slack-Davis, J.K.1
Parsons, J.T.2
-
90
-
-
84877697461
-
D-pinitol inhibits prostate cancer metastasis through inhibition of aVb3 integrin by modulating FAK, c-Src and NF-kB pathways
-
Lin TH, Tan TW, Tsai TH et al. d-pinitol inhibits prostate cancer metastasis through inhibition of aVb3 integrin by modulating FAK, c-Src and NF-kB pathways. Int. J. Mol. Sci. 14(5), 9790-9802 (2013
-
(2013)
Int. J. Mol. Sci
, vol.14
, Issue.5
, pp. 9790-9802
-
-
Lin, T.H.1
Tan, T.W.2
Tsai, T.H.3
-
91
-
-
0032763013
-
Combined treatment with serine protease inhibitor aprotinin and matrix metalloproteinase inhibitor batimastat (BB-94) does not prevent invasion of human esophageal and ovarian carcinoma cells in vivo
-
Della Porta P, Soeltl R, Krell HW et al. Combined treatment with serine protease inhibitor aprotinin and matrix metalloproteinase inhibitor batimastat (BB-94) does not prevent invasion of human esophageal and ovarian carcinoma cells in vivo. Anticancer Res. 19(5B), 3809-3816 (1999
-
(1999)
Anticancer Res
, vol.19
, Issue.5 B
, pp. 3809-3816
-
-
Della Porta, P.1
Soeltl, R.2
Krell, H.W.3
-
92
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
-
Coussens LM, Fingleton B, Matrisian LM. Matrix metalloproteinase inhibitors and cancer: Trials and tribulations. Science 295(5564), 2387-2392 (2002
-
(2002)
Science
, vol.295
, Issue.5564
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
93
-
-
36849073658
-
MMPs as therapeutic targets - still a viable option?
-
Fingleton B. MMPs as therapeutic targets - still a viable option? Semin. Cell. Dev. Biol. 19(1), 61-68 (2008
-
(2008)
Semin. Cell. Dev. Biol
, vol.19
, Issue.1
, pp. 61-68
-
-
Fingleton, B.1
-
94
-
-
72949119124
-
Integrins in cancer: Biological implications and therapeutic opportunities
-
Desgrosellier JS, Cheresh DA. Integrins in cancer: Biological implications and therapeutic opportunities. Nat. Rev. Cancer 10(1), 9-22 (2010
-
(2010)
Nat. Rev. Cancer
, vol.10
, Issue.1
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
95
-
-
59449108662
-
Matrix metalloproteinase 2-integrin a(v)b3 binding is required for mesenchymal cell invasive activity but not epithelial locomotion: A computational time-lapse study
-
Rupp PA, Visconti RP, Czirok A, Cheresh DA, Little CD. Matrix metalloproteinase 2-integrin a(v)b3 binding is required for mesenchymal cell invasive activity but not epithelial locomotion: A computational time-lapse study. Mol. Biol. Cell. 19(12), 5529-5540 (2008
-
(2008)
Mol. Biol. Cell
, vol.19
, Issue.12
, pp. 5529-5540
-
-
Rupp, P.A.1
Visconti, R.P.2
Czirok, A.3
Cheresh, D.A.4
Little, C.D.5
-
96
-
-
0034686685
-
Potent and selective mechanism-based inhibition of gelatinases
-
Brown S, Bernardo MM, Li Z-H et al. Potent and selective mechanism-based inhibition of gelatinases. J. Am. Chem. Soc. 122(28), 6799-6800 (2000
-
(2000)
J. Am. Chem. Soc
, vol.122
, Issue.28
, pp. 6799-6800
-
-
Brown, S.1
Bernardo, M.M.2
Li, Z.-H.3
-
97
-
-
33646352955
-
Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor
-
Bonfil RD, Sabbota A, Nabha S et al. Inhibition of human prostate cancer growth, osteolysis and angiogenesis in a bone metastasis model by a novel mechanism-based selective gelatinase inhibitor. Int. J. Cancer 118(11), 2721-2726 (2006
-
(2006)
Int. J. Cancer
, vol.118
, Issue.11
, pp. 2721-2726
-
-
Bonfil, R.D.1
Sabbota, A.2
Nabha, S.3
-
98
-
-
18144370787
-
Antimetastatic activity of a novel mechanism-based gelatinase inhibitor
-
Kruger A, Arlt MJ, Gerg M et al. Antimetastatic activity of a novel mechanism-based gelatinase inhibitor. Cancer Res. 65(9), 3523-3526 (2005
-
(2005)
Cancer Res
, vol.65
, Issue.9
, pp. 3523-3526
-
-
Kruger, A.1
Arlt, M.J.2
Gerg, M.3
-
99
-
-
78650780565
-
New strategies for the next generation of matrix-metalloproteinase inhibitors: Selectively targeting membrane-Anchored mmps with therapeutic antibodies
-
Devy L, Dransfield DT. New strategies for the next generation of matrix-metalloproteinase inhibitors: Selectively targeting membrane-Anchored mmps with therapeutic antibodies. Biochem. Res. Int. 2011, 191670 (2011
-
(2011)
Biochem. Res. Int
, vol.2011
, pp. 191670
-
-
Devy, L.1
Dransfield, D.T.2
-
100
-
-
60649108677
-
Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis
-
Devy L, Huang L, Naa L et al. Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis. Cancer Res. 69(4), 1517-1526 (2009
-
(2009)
Cancer Res
, vol.69
, Issue.4
, pp. 1517-1526
-
-
Devy, L.1
Huang, L.2
Naa, L.3
-
101
-
-
77956279673
-
Development of a novel tumor-Targeted vascular disrupting agent activated by membrane-Type matrix metalloproteinases
-
Atkinson JM, Falconer RA, Edwards DR et al. Development of a novel tumor-Targeted vascular disrupting agent activated by membrane-Type matrix metalloproteinases. Cancer Res. 70(17), 6902-6912 (2010
-
(2010)
Cancer Res
, vol.70
, Issue.17
, pp. 6902-6912
-
-
Atkinson, J.M.1
Falconer, R.A.2
Edwards, D.R.3
-
102
-
-
62849099048
-
Circulating tumour cells as prognostic markers in progressive, castration-resistant prostate cancer: A reanalysis of IMMC38 trial data
-
Scher HI, Jia X, De Bono JS et al. Circulating tumour cells as prognostic markers in progressive, castration-resistant prostate cancer: A reanalysis of IMMC38 trial data. Lancet Oncol. 10(3), 233-239 (2009
-
(2009)
Lancet Oncol
, vol.10
, Issue.3
, pp. 233-239
-
-
Scher, H.I.1
Jia, X.2
De Bono, J.S.3
-
103
-
-
84863792455
-
Nanobiotechnology for the capture and manipulation of circulating tumor cells
-
Hughes AD, King MR. Nanobiotechnology for the capture and manipulation of circulating tumor cells. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 4(3), 291-309 (2012
-
(2012)
Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol
, vol.4
, Issue.3
, pp. 291-309
-
-
Hughes, A.D.1
King, M.R.2
-
104
-
-
79551693066
-
Circulating tumor cells: Approaches to isolation and characterization
-
Yu M, Stott S, Toner M, Maheswaran S, Haber DA. Circulating tumor cells: Approaches to isolation and characterization. J. Cell Biol. 192(3), 373-382 (2011
-
(2011)
J. Cell Biol
, vol.192
, Issue.3
, pp. 373-382
-
-
Yu, M.1
Stott, S.2
Toner, M.3
Maheswaran, S.4
Haber, D.A.5
-
105
-
-
22344455007
-
Clinical effects of a chimeric anti-EpCAM monoclonal antibody in combination with granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma
-
Liljefors M, Nilsson B, Fagerberg J, Ragnhammar P, Mellstedt H, Frodin JE. Clinical effects of a chimeric anti-EpCAM monoclonal antibody in combination with granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma. Int. J. Oncol. 26(6), 1581-1589 (2005
-
(2005)
Int. J. Oncol
, vol.26
, Issue.6
, pp. 1581-1589
-
-
Liljefors, M.1
Nilsson, B.2
Fagerberg, J.3
Ragnhammar, P.4
Mellstedt, H.5
Frodin, J.E.6
-
106
-
-
77649342617
-
Targeting hematogenous spread of circulating tumor cells by a chemotactic drug-eluting IVC filter to prevent pulmonary and systemic metastasis
-
Faltas B. Targeting hematogenous spread of circulating tumor cells by a chemotactic drug-eluting IVC filter to prevent pulmonary and systemic metastasis. Med. Hypotheses 74(4), 668-669 (2010
-
(2010)
Med. Hypotheses
, vol.74
, Issue.4
, pp. 668-669
-
-
Faltas, B.1
-
107
-
-
62549090127
-
CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts
-
Marangoni E, Lecomte N, Durand L et al. CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts. Br. J. Cancer 100(6), 918-922 (2009
-
(2009)
Br. J. Cancer
, vol.100
, Issue.6
, pp. 918-922
-
-
Marangoni, E.1
Lecomte, N.2
Durand, L.3
-
108
-
-
36049048637
-
Suppression of human colon cancer tumors in nude mice by siRNA CD44 gene therapy
-
Subramaniam V, Vincent IR, Gilakjan M, Jothy S. Suppression of human colon cancer tumors in nude mice by siRNA CD44 gene therapy. Exp. Mol. Pathol. 83(3), 332-340 (2007
-
(2007)
Exp. Mol. Pathol
, vol.83
, Issue.3
, pp. 332-340
-
-
Subramaniam, V.1
Vincent, I.R.2
Gilakjan, M.3
Jothy, S.4
-
109
-
-
77951871638
-
Changes in bone health and skeletal-related events following implementation of a multidisciplinary consensus statement guiding surveillance and treatment of men undergoing androgen deprivation therapy for prostate cancer
-
Nelson DM, Peterson AC. Changes in bone health and skeletal-related events following implementation of a multidisciplinary consensus statement guiding surveillance and treatment of men undergoing androgen deprivation therapy for prostate cancer. Aging Male 13(2), 120-123 (2010
-
(2010)
Aging Male
, vol.13
, Issue.2
, pp. 120-123
-
-
Nelson, D.M.1
Peterson, A.C.2
-
110
-
-
0034984095
-
The role of zoledronic acid in cancer: Clinical studies in the treatment and prevention of bone metastases
-
Coleman RE, Seaman JJ. The role of zoledronic acid in cancer: Clinical studies in the treatment and prevention of bone metastases. Semin. Oncol. 28(2 Suppl. 6), 11-16 (2001
-
(2001)
Semin. Oncol
, vol.28
, Issue.2 SUPPL. 6
, pp. 11-16
-
-
Coleman, R.E.1
Seaman, J.J.2
-
111
-
-
10744229392
-
Approval summary for zoledronic acid for treatment of multiple myeloma and cancer bone metastases
-
Ibrahim A, Scher N, Williams G et al. Approval summary for zoledronic acid for treatment of multiple myeloma and cancer bone metastases. Clin. Cancer Res. 9(7), 2394-2399 (2003
-
(2003)
Clin. Cancer Res
, vol.9
, Issue.7
, pp. 2394-2399
-
-
Ibrahim, A.1
Scher, N.2
Williams, G.3
-
112
-
-
14444272043
-
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-Terminal kinase in T cells
-
Wong BR, Rho J, Arron J et al. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-Terminal kinase in T cells. J. Biol. Chem. 272(40), 25190-25194 (1997
-
(1997)
J. Biol. Chem
, vol.272
, Issue.40
, pp. 25190-25194
-
-
Wong, B.R.1
Rho, J.2
Arron, J.3
-
113
-
-
78149284013
-
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer
-
Schramek D, Leibbrandt A, Sigl V et al. Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature 468(7320), 98-102 (2010
-
(2010)
Nature
, vol.468
, Issue.7320
, pp. 98-102
-
-
Schramek, D.1
Leibbrandt, A.2
Sigl, V.3
-
114
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
Lacey DL, Timms E, Tan HL et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93(2), 165-176 (1998
-
(1998)
Cell
, vol.93
, Issue.2
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.L.3
-
115
-
-
77953672623
-
Denosumab
-
Pageau SC. Denosumab. MAbs 1(3), 210-215 (2009
-
(2009)
MAbs
, vol.1
, Issue.3
, pp. 210-215
-
-
Pageau, S.C.1
-
116
-
-
67649791971
-
Denosumab treatment of prostate cancer with bone metastases and increased urine N-Telopeptide levels after therapy with intravenous bisphosphonates: Results of a randomized Phase II trial
-
discussion 515-516
-
Fizazi K, Bosserman L, Gao G, Skacel T, Markus R. Denosumab treatment of prostate cancer with bone metastases and increased urine N-Telopeptide levels after therapy with intravenous bisphosphonates: Results of a randomized Phase II trial. J. Urol. 182(2), 509-515; discussion 515-516 (2009
-
(2009)
J. Urol
, vol.182
, Issue.2
, pp. 509-515
-
-
Fizazi, K.1
Bosserman, L.2
Gao, G.3
Skacel, T.4
Markus, R.5
-
117
-
-
79952360832
-
Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: A randomised, double-blind study
-
Fizazi K, Carducci M, Smith M et al. Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: A randomised, double-blind study. Lancet 377(9768), 813-822 (2011
-
(2011)
Lancet
, vol.377
, Issue.9768
, pp. 813-822
-
-
Fizazi, K.1
Carducci, M.2
Smith, M.3
-
118
-
-
84855516339
-
Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: Results of a Phase 3, randomised, placebo-controlled trial
-
Smith MR, Saad F, Coleman R et al. Denosumab and bone-metastasis-free survival in men with castration-resistant prostate cancer: Results of a Phase 3, randomised, placebo-controlled trial. Lancet 379(9810), 39-46 (2012
-
(2012)
Lancet
, vol.379
, Issue.9810
, pp. 39-46
-
-
Smith, M.R.1
Saad, F.2
Coleman, R.3
-
119
-
-
75749116783
-
Pharmacokinetic assessment of the uptake of 16b-18F-fluoro-5a- dihydrotestosterone (FDHT) in prostate tumors as measured by PET
-
Beattie BJ, Smith-Jones PM, Jhanwar YS et al. Pharmacokinetic assessment of the uptake of 16b-18F-fluoro-5a-dihydrotestosterone (FDHT) in prostate tumors as measured by PET. J. Nucl. Med. 51(2), 183-192 (2010
-
(2010)
J. Nucl. Med
, vol.51
, Issue.2
, pp. 183-192
-
-
Beattie, B.J.1
Smith-Jones, P.M.2
Jhanwar, Y.S.3
-
120
-
-
79956327484
-
Detection of recurrent prostate carcinoma with anti-1-Amino-3-18F- fluorocyclobutane-1-carboxylic acid PET/CT and 111In-capromab pendetide SPECT/CT
-
Schuster DM, Savir-Baruch B, Nieh PT et al. Detection of recurrent prostate carcinoma with anti-1-Amino-3-18F-fluorocyclobutane-1-carboxylic acid PET/CT and 111In-capromab pendetide SPECT/CT. Radiology 259(3), 852-861 (2011
-
(2011)
Radiology
, vol.259
, Issue.3
, pp. 852-861
-
-
Schuster, D.M.1
Savir-Baruch, B.2
Nieh, P.T.3
|