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Volumn 21, Issue 11, 2010, Pages 1810-1824

Involvement of the cytoskeleton in controlling leading-edge function during chemotaxis

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOATTRACTANT; CYCLIC AMP; F ACTIN; GREEN FLUORESCENT PROTEIN; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; MYOSIN II; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN CDC42; PROTEIN KINASE B; RAC1 PROTEIN; RAS PROTEIN; TOR COMPLEX 2; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; CTXA PROTEIN, DICTYOSTELIUM DISCOIDEUM; CTXB PROTEIN, DICTYOSTELIUM DISCOIDEUM; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HYBRID PROTEIN; PROTOZOAL PROTEIN;

EID: 77952925797     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E10-01-0009     Document Type: Article
Times cited : (43)

References (84)
  • 1
    • 0030926552 scopus 로고    scopus 로고
    • Dictyostelium IQGAP-related protein specifically involved in the completion of cytokinesis
    • Adachi, H., Takahashi, Y., Hasebe, T., Shirouzu, M., Yokoyama, S., and Sutoh, K. (1997). Dictyostelium IQGAP-related protein specifically involved in the completion of cytokinesis. J. Cell Biol. 137, 891-898.
    • (1997) J. Cell Biol. , vol.137 , pp. 891-898
    • Adachi, H.1    Takahashi, Y.2    Hasebe, T.3    Shirouzu, M.4    Yokoyama, S.5    Sutoh, K.6
  • 3
    • 33749472179 scopus 로고    scopus 로고
    • Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum
    • Bolourani, P., Spiegelman, G. B., and Weeks, G. (2006). Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum. Mol. Biol. Cell 17, 4543-4550.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 4543-4550
    • Bolourani, P.1    Spiegelman, G.B.2    Weeks, G.3
  • 4
    • 0037009436 scopus 로고    scopus 로고
    • A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium
    • Bosgraaf, L., Russcher, H., Smith, J. L., Wessels, D., Soll, D. R., and Van Haastert, P. J. (2002). A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium. EMBO J. 21, 4560-4570.
    • (2002) EMBO J. , vol.21 , pp. 4560-4570
    • Bosgraaf, L.1    Russcher, H.2    Smith, J.L.3    Wessels, D.4    Soll, D.R.5    Van Haastert, P.J.6
  • 5
    • 33748256486 scopus 로고    scopus 로고
    • The regulation of myosin II in Dictyostelium
    • Bosgraaf, L., and Van Haastert, P. J. (2006). The regulation of myosin II in Dictyostelium. Eur. J. Cell Biol. 85, 969-979.
    • (2006) Eur. J. Cell Biol. , vol.85 , pp. 969-979
    • Bosgraaf, L.1    Van Haastert, P.J.2
  • 6
    • 59149089007 scopus 로고    scopus 로고
    • PI3-kinase signaling contributes to orientation in shallow gradients and enhances speed in steep chemoattractant gradients
    • Bosgraaf, L., Keizer-Gunnink, I., and Van Haastert, P. J. (2008). PI3-kinase signaling contributes to orientation in shallow gradients and enhances speed in steep chemoattractant gradients. J. Cell Sci. 121, 3589-3597.
    • (2008) J. Cell Sci. , vol.121 , pp. 3589-3597
    • Bosgraaf, L.1    Keizer-Gunnink, I.2    Van Haastert, P.J.3
  • 7
    • 54249137797 scopus 로고    scopus 로고
    • Feedback loops shape cellular signals in space and time
    • Brandman, O., and Meyer, T. (2008). Feedback loops shape cellular signals in space and time. Science 322, 390-395.
    • (2008) Science , vol.322 , pp. 390-395
    • Brandman, O.1    Meyer, T.2
  • 8
    • 35748946040 scopus 로고    scopus 로고
    • Get to grips: Steering local actin dynamics with IQGAPs
    • Brandt, D. T., and Grosse, R. (2007). Get to grips: steering local actin dynamics with IQGAPs. EMBO Rep. 8, 1019-1023.
    • (2007) EMBO Rep. , vol.8 , pp. 1019-1023
    • Brandt, D.T.1    Grosse, R.2
  • 9
    • 0043093686 scopus 로고    scopus 로고
    • IQGAP proteins are integral components of cytoskeletal regulation
    • Briggs, M. W., and Sacks, D. B. (2003). IQGAP proteins are integral components of cytoskeletal regulation. EMBO Rep. 4, 571-574.
    • (2003) EMBO Rep. , vol.4 , pp. 571-574
    • Briggs, M.W.1    Sacks, D.B.2
  • 10
    • 33745607882 scopus 로고    scopus 로고
    • Feedback signaling controls leading-edge formation during chemotaxis
    • Charest, P. G., and Firtel, R. A. (2006). Feedback signaling controls leading-edge formation during chemotaxis. Curr. Opin. Genet. Dev. 16, 339-347.
    • (2006) Curr. Opin. Genet. Dev. , vol.16 , pp. 339-347
    • Charest, P.G.1    Firtel, R.A.2
  • 12
    • 0034625002 scopus 로고    scopus 로고
    • Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells
    • Chung, C. Y., Lee, S., Briscoe, C., Ellsworth, C., and Firtel, R. A. (2000). Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells. Proc. Natl. Acad. Sci. USA 97, 5225-5230.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 5225-5230
    • Chung, C.Y.1    Lee, S.2    Briscoe, C.3    Ellsworth, C.4    Firtel, R.A.5
  • 13
    • 0035869375 scopus 로고    scopus 로고
    • Regulation of Dictyostelium myosin I and II
    • de la Roche, M. A., and Cote, G. P. (2001). Regulation of Dictyostelium myosin I and II. Biochim. Biophys. Acta 1525, 245-261.
    • (2001) Biochim. Biophys. Acta , vol.1525 , pp. 245-261
    • De La Roche, M.A.1    Cote, G.P.2
  • 16
    • 0027372314 scopus 로고
    • Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo
    • Egelhoff, T. T., Lee, R. J., and Spudich, J. A. (1993). Dictyostelium myosin heavy chain phosphorylation sites regulate myosin filament assembly and localization in vivo. Cell 75, 363-371.
    • (1993) Cell , vol.75 , pp. 363-371
    • Egelhoff, T.T.1    Lee, R.J.2    Spudich, J.A.3
  • 17
    • 0029945399 scopus 로고    scopus 로고
    • Myosin-based cortical tension in Dictyostelium resolved into heavy and light chain-regulated components
    • Egelhoff, T. T., Naismith, T. V., and Brozovich, F. V. (1996). Myosin-based cortical tension in Dictyostelium resolved into heavy and light chain-regulated components. J. Muscle Res. Cell Motil. 17, 269-274.
    • (1996) J. Muscle Res. Cell Motil. , vol.17 , pp. 269-274
    • Egelhoff, T.T.1    Naismith, T.V.2    Brozovich, F.V.3
  • 18
    • 0032554902 scopus 로고    scopus 로고
    • Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body
    • Eng, K., Naqvi, N. I., Wong, K. C., and Balasubramanian, M. K. (1998). Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body. Curr. Biol. 8, 611-621.
    • (1998) Curr. Biol. , vol.8 , pp. 611-621
    • Eng, K.1    Naqvi, N.I.2    Wong, K.C.3    Balasubramanian, M.K.4
  • 19
    • 0031768407 scopus 로고    scopus 로고
    • The IQGAP-related protein DGAP1 interacts with Rac and is involved in the modulation of the F-actin cytoskeleton and control of cell motility
    • Faix, J., Clougherty, C., Konzok, A., Mintert, U., Murphy, J., Albrecht, R., Muhlbauer, B., and Kuhlmann, J. (1998). The IQGAP-related protein DGAP1 interacts with Rac and is involved in the modulation of the F-actin cytoskeleton and control of cell motility. J. Cell Sci. 111, 3059-3071.
    • (1998) J. Cell Sci. , vol.111 , pp. 3059-3071
    • Faix, J.1    Clougherty, C.2    Konzok, A.3    Mintert, U.4    Murphy, J.5    Albrecht, R.6    Muhlbauer, B.7    Kuhlmann, J.8
  • 20
    • 0035898686 scopus 로고    scopus 로고
    • Recruitment of cortexillin into the cleavage furrow is controlled by Rac1 and IQGAP-related proteins
    • Faix, J., Weber, I., Mintert, U., Kohler, J., Lottspeich, F., and Marriott, G. (2001). Recruitment of cortexillin into the cleavage furrow is controlled by Rac1 and IQGAP-related proteins. EMBO J. 20, 3705-3715.
    • (2001) EMBO J. , vol.20 , pp. 3705-3715
    • Faix, J.1    Weber, I.2    Mintert, U.3    Kohler, J.4    Lottspeich, F.5    Marriott, G.6
  • 21
    • 0033924129 scopus 로고    scopus 로고
    • Dictyostelium: A model for regulated cell movement during morphogenesis
    • Firtel, R. A., and Meili, R. (2000). Dictyostelium: a model for regulated cell movement during morphogenesis. Curr. Opin. Genet. Dev. 10, 421-427.
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 421-427
    • Firtel, R.A.1    Meili, R.2
  • 22
    • 0037205265 scopus 로고    scopus 로고
    • Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis
    • Funamoto, S., Meili, R., Lee, S., Parry, L., and Firtel, R. A. (2002). Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell 109, 611-623.
    • (2002) Cell , vol.109 , pp. 611-623
    • Funamoto, S.1    Meili, R.2    Lee, S.3    Parry, L.4    Firtel, R.A.5
  • 23
    • 0035858886 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in Dictyostelium
    • Funamoto, S., Milan, K., Meili, R., and Firtel, R. A. (2001). Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in Dictyostelium. J. Cell Biol. 153, 795-810.
    • (2001) J. Cell Biol. , vol.153 , pp. 795-810
    • Funamoto, S.1    Milan, K.2    Meili, R.3    Firtel, R.A.4
  • 24
    • 3342968642 scopus 로고    scopus 로고
    • Phg2 a kinase involved in adhesion and focal site modeling in Dictyostelium
    • Gebbie, L., et al. (2004). Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium. Mol. Biol. Cell 15, 3915-3925.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 3915-3925
    • Gebbie, L.1
  • 25
    • 2342648911 scopus 로고    scopus 로고
    • Dynacortin contributes to cortical viscoelasticity and helps define the shape changes of cytokinesis
    • Girard, K., Chaney, C., Delannoy, M., Kuo, S., and Robinson, D. (2004). Dynacortin contributes to cortical viscoelasticity and helps define the shape changes of cytokinesis. EMBO J. 23, 1536-1546.
    • (2004) EMBO J. , vol.23 , pp. 1536-1546
    • Girard, K.1    Chaney, C.2    Delannoy, M.3    Kuo, S.4    Robinson, D.5
  • 26
    • 33144468161 scopus 로고    scopus 로고
    • Dictyostelium myosin-II mechanochemistry promotes active behavior of the cortex on long time-scales
    • Girard, K., Kuo, S., and Robinson, D. (2006). Dictyostelium myosin-II mechanochemistry promotes active behavior of the cortex on long time-scales. Proc. Natl. Acad. Sci. USA 103, 2103-2108.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2103-2108
    • Girard, K.1    Kuo, S.2    Robinson, D.3
  • 27
    • 0024044667 scopus 로고
    • Relationship of pseudopod extension to chemotactic hormone-induced actin polymerization in amoeboid cells
    • Hall, A. L., Schlein, A., and Condeelis, J. (1988). Relationship of pseudopod extension to chemotactic hormone-induced actin polymerization in amoeboid cells. J. Cell. Biochem. 37, 285-299.
    • (1988) J. Cell. Biochem. , vol.37 , pp. 285-299
    • Hall, A.L.1    Schlein, A.2    Condeelis, J.3
  • 29
    • 0037205230 scopus 로고    scopus 로고
    • Tumor suppressor PTEN mediates sensing of chemoattractant gradients
    • Iijima, M., and Devreotes, P. (2002). Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell 109, 599-610.
    • (2002) Cell , vol.109 , pp. 599-610
    • Iijima, M.1    Devreotes, P.2
  • 30
    • 0028287369 scopus 로고
    • Two cAMP receptors activate common signaling pathways in Dictyostelium
    • Insall, R. H., Soede, R. D., Schaap, P., and Devreotes, P. N. (1994). Two cAMP receptors activate common signaling pathways in Dictyostelium. Mol. Biol. Cell 5, 703-711.
    • (1994) Mol. Biol. Cell , vol.5 , pp. 703-711
    • Insall, R.H.1    Soede, R.D.2    Schaap, P.3    Devreotes, P.N.4
  • 31
    • 44449172361 scopus 로고    scopus 로고
    • Directional sensing during chemotaxis
    • Janetopoulos, C., and Firtel, R. A. (2008). Directional sensing during chemotaxis. FEBS Lett. 582, 2075-2085.
    • (2008) FEBS Lett. , vol.582 , pp. 2075-2085
    • Janetopoulos, C.1    Firtel, R.A.2
  • 32
    • 33947718091 scopus 로고    scopus 로고
    • Rap1 controls cell adhesion and cell motility through the regulation of myosin II
    • DOI 10.1083/jcb.200607072
    • Jeon, T. J., Lee, D. J., Merlot, S., Weeks, G., and Firtel, R. A. (2007). Rap1 controls cell adhesion and cell motility through the regulation of myosin II. J. Cell Biol. 176, 1021-1033. (Pubitemid 46506974)
    • (2007) Journal of Cell Biology , vol.176 , Issue.7 , pp. 1021-1033
    • Jeon, T.J.1    Lee, D.-J.2    Merlot, S.3    Weeks, G.4    Firtel, R.A.5
  • 33
    • 53149136171 scopus 로고    scopus 로고
    • Chemotaxis, chemokine receptors and human disease
    • Jin, T., Xu, X., and Hereld, D. (2008). Chemotaxis, chemokine receptors and human disease. Cytokine 44, 1-8.
    • (2008) Cytokine , vol.44 , pp. 1-8
    • Jin, T.1    Xu, X.2    Hereld, D.3
  • 35
    • 34247884549 scopus 로고    scopus 로고
    • Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs
    • Kae, H., Kortholt, A., Rehmann, H., Insall, R. H., Van Haastert, P. J., Spiegelman, G. B., and Weeks, G. (2007). Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs. EMBO Rep. 8, 477-482.
    • (2007) EMBO Rep. , vol.8 , pp. 477-482
    • Kae, H.1    Kortholt, A.2    Rehmann, H.3    Insall, R.H.4    Van Haastert, P.J.5    Spiegelman, G.B.6    Weeks, G.7
  • 36
    • 47049110588 scopus 로고    scopus 로고
    • PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis
    • Kamimura, Y., Xiong, Y., Iglesias, P. A., Hoeller, O., Bolourani, P., and Devreotes, P. N. (2008). PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis. Curr. Biol. 18, 1034-1043.
    • (2008) Curr. Biol. , vol.18 , pp. 1034-1043
    • Kamimura, Y.1    Xiong, Y.2    Iglesias, P.A.3    Hoeller, O.4    Bolourani, P.5    Devreotes, P.N.6
  • 37
    • 33746911971 scopus 로고    scopus 로고
    • Chemoattractant receptor signaling and the control of lymphocyte migration
    • Kehrl, J. H. (2006). Chemoattractant receptor signaling and the control of lymphocyte migration. Immunol. Res. 34, 211-227.
    • (2006) Immunol. Res. , vol.34 , pp. 211-227
    • Kehrl, J.H.1
  • 38
    • 70349428806 scopus 로고    scopus 로고
    • Chemotaxis: Finding the way forward with Dictyostelium
    • King, J. S., and Insall, R. H. (2009). Chemotaxis: finding the way forward with Dictyostelium. Trends Cell Biol. 19, 523-530.
    • (2009) Trends Cell Biol. , vol.19 , pp. 523-530
    • King, J.S.1    Insall, R.H.2
  • 39
    • 42149177825 scopus 로고    scopus 로고
    • The regulation of cell motility and chemotaxis by phospholipid signaling
    • Koelsch, V., Charest, P. G., and Firtel, R. A. (2008). The regulation of cell motility and chemotaxis by phospholipid signaling. J. Cell Sci. 121, 551-559.
    • (2008) J. Cell Sci. , vol.121 , pp. 551-559
    • Koelsch, V.1    Charest, P.G.2    Firtel, R.A.3
  • 41
    • 45449120580 scopus 로고    scopus 로고
    • Highlighting the role of Ras and Rap during Dictyostelium chemotaxis
    • Kortholt, A., and Van Haastert, P. J. (2008). Highlighting the role of Ras and Rap during Dictyostelium chemotaxis. Cell Signal. 20, 1415-1422.
    • (2008) Cell Signal , vol.20 , pp. 1415-1422
    • Kortholt, A.1    Van Haastert, P.J.2
  • 42
    • 0141502119 scopus 로고    scopus 로고
    • Cross-linking of actin filaments by myosin II is a major contributor to cortical integrity and cell motility in restrictive environments
    • Laevsky, G., and Knecht, D. A. (2003). Cross-linking of actin filaments by myosin II is a major contributor to cortical integrity and cell motility in restrictive environments. J. Cell Sci. 116, 3761-3770.
    • (2003) J. Cell Sci. , vol.116 , pp. 3761-3770
    • Laevsky, G.1    Knecht, D.A.2
  • 44
    • 0030934487 scopus 로고    scopus 로고
    • A Ras GAP is essential for cytokinesis and spatial patterning in Dictyostelium
    • Lee, S., Escalante, R., and Firtel, R. A. (1997). A Ras GAP is essential for cytokinesis and spatial patterning in Dictyostelium. Development 124, 983-996.
    • (1997) Development , vol.124 , pp. 983-996
    • Lee, S.1    Escalante, R.2    Firtel, R.A.3
  • 45
    • 0032849043 scopus 로고    scopus 로고
    • A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium
    • Lee, S., Parent, C. A., Insall, R., and Firtel, R. A. (1999). A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium. Mol. Biol. Cell 10, 2829-2845.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 2829-2845
    • Lee, S.1    Parent, C.A.2    Insall, R.3    Firtel, R.A.4
  • 46
    • 0036837846 scopus 로고    scopus 로고
    • Myosin II dynamics in Dictyostelium: Determinants for filament assembly and translocation to the cell cortex during chemoattractant responses
    • Levi, S., Polyakov, M. V., and Egelhoff, T. T. (2002). Myosin II dynamics in Dictyostelium: determinants for filament assembly and translocation to the cell cortex during chemoattractant responses. Cell Motil. Cytoskelet. 53, 177-188.
    • (2002) Cell Motil. Cytoskelet. , vol.53 , pp. 177-188
    • Levi, S.1    Polyakov, M.V.2    Egelhoff, T.T.3
  • 48
    • 0041352963 scopus 로고    scopus 로고
    • Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42
    • Li, Z., et al. (2003). Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42. Cell 114, 215-227.
    • (2003) Cell , vol.114 , pp. 215-227
    • Li, Z.1
  • 49
    • 34249649748 scopus 로고    scopus 로고
    • Traction force microscopy in Dictyostelium reveals distinct roles for myosin II motor and actin-crosslinking activity in polarized cell movement
    • Lombardi, M. L., Knecht, D. A., Dembo, M., and Lee, J. (2007). Traction force microscopy in Dictyostelium reveals distinct roles for myosin II motor and actin-crosslinking activity in polarized cell movement. J. Cell Sci. 120, 1624-1634.
    • (2007) J. Cell Sci. , vol.120 , pp. 1624-1634
    • Lombardi, M.L.1    Knecht, D.A.2    Dembo, M.3    Lee, J.4
  • 51
    • 76049104121 scopus 로고    scopus 로고
    • Myosin II Is essential for the spatiotemporal organization of traction forces during cell motility
    • Meili, R., Alonso-Latorre, B., del Alamo, J. C., Firtel, R. A., and Lasheras, J. C. (2010) Myosin II Is essential for the spatiotemporal organization of traction forces during cell motility. Mol. Biol. Cell 21, 405-417.
    • (2010) Mol. Biol. Cell , vol.21 , pp. 405-417
    • Meili, R.1    Alonso-Latorre, B.2    Del Alamo, J.C.3    Firtel, R.A.4    Lasheras, J.C.5
  • 52
    • 0034659225 scopus 로고    scopus 로고
    • A novel Akt/PKB-related kinase is essential for morphogenesis in Dictyostelium. Curr
    • Meili, R., Ellsworth, C., and Firtel, R. A. (2000). A novel Akt/PKB-related kinase is essential for morphogenesis in Dictyostelium. Curr. Biol. 10, 708-717.
    • (2000) Biol. , vol.10 , pp. 708-717
    • Meili, R.1    Ellsworth, C.2    Firtel, R.A.3
  • 53
    • 0033560747 scopus 로고    scopus 로고
    • Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium
    • Meili, R., Ellsworth, C., Lee, S., Reddy, T. B., Ma, H., and Firtel, R. A. (1999). Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J. 18, 2092-2105.
    • (1999) EMBO J. , vol.18 , pp. 2092-2105
    • Meili, R.1    Ellsworth, C.2    Lee, S.3    Reddy, T.B.4    Ma, H.5    Firtel, R.A.6
  • 55
    • 0035092686 scopus 로고    scopus 로고
    • A myosin II mutation uncouples ATPase activity from motility and shortens step size
    • Murphy, C., Rock, R., and Spudich, J. (2001a). A myosin II mutation uncouples ATPase activity from motility and shortens step size. Nat. Cell Biol. 3, 311-315.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 311-315
    • Murphy, C.1    Rock, R.2    Spudich, J.3
  • 56
    • 0035092686 scopus 로고    scopus 로고
    • A myosin II mutation uncouples ATPase activity from motility and shortens step size
    • Murphy, C. T., Rock, R. S., and Spudich, J. A. (2001b). A myosin II mutation uncouples ATPase activity from motility and shortens step size. Nat. Cell Biol. 3, 311-315.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 311-315
    • Murphy, C.T.1    Rock, R.S.2    Spudich, J.A.3
  • 57
    • 0032572583 scopus 로고    scopus 로고
    • Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton
    • Osman, M. A., and Cerione, R. A. (1998). Iqg1p, a yeast homologue of the mammalian IQGAPs, mediates cdc42p effects on the actin cytoskeleton. J. Cell Biol. 142, 443-455.
    • (1998) J. Cell Biol. , vol.142 , pp. 443-455
    • Osman, M.A.1    Cerione, R.A.2
  • 58
    • 0032475863 scopus 로고    scopus 로고
    • G protein signaling events are activated at the leading edge of chemotactic cells
    • Parent, C. A., Blacklock, B. J., Froehlich, W. M., Murphy, D. B., and Devreotes, P. N. (1998). G protein signaling events are activated at the leading edge of chemotactic cells. Cell 95, 81-91.
    • (1998) Cell , vol.95 , pp. 81-91
    • Parent, C.A.1    Blacklock, B.J.2    Froehlich, W.M.3    Murphy, D.B.4    Devreotes, P.N.5
  • 59
    • 8444247968 scopus 로고    scopus 로고
    • Rac regulation of chemotaxis and morphogenesis in Dictyostelium
    • Park, K. C., Rivero, F., Meili, R., Lee, S., Apone, F., and Firtel, R. A. (2004). Rac regulation of chemotaxis and morphogenesis in Dictyostelium. EMBO J. 23, 4177-4189.
    • (2004) EMBO J. , vol.23 , pp. 4177-4189
    • Park, K.C.1    Rivero, F.2    Meili, R.3    Lee, S.4    Apone, F.5    Firtel, R.A.6
  • 60
    • 67649464358 scopus 로고    scopus 로고
    • PTEN is a mechanosensing signal transducer for myosin II localization in Dictyostelium cells
    • Pramanik, M. K., Iijima, M., Iwadate, Y., and Yumura, S. (2009). PTEN is a mechanosensing signal transducer for myosin II localization in Dictyostelium cells. Genes Cells 14, 821-834.
    • (2009) Genes Cells , vol.14 , pp. 821-834
    • Pramanik, M.K.1    Iijima, M.2    Iwadate, Y.3    Yumura, S.4
  • 61
    • 0031569406 scopus 로고    scopus 로고
    • Mutational analysis of the role of Rap1 in regulating cytoskeletal function in Dictyostelium
    • Rebstein, P. J., Cardelli, J., Weeks, G., and Spiegelman, G. B. (1997). Mutational analysis of the role of Rap1 in regulating cytoskeletal function in Dictyostelium. Exp. Cell Res. 231, 276-283.
    • (1997) Exp. Cell Res. , vol.231 , pp. 276-283
    • Rebstein, P.J.1    Cardelli, J.2    Weeks, G.3    Spiegelman, G.B.4
  • 63
    • 69949183991 scopus 로고    scopus 로고
    • Mechanosensing through cooperative interactions between myosin II and the actin crosslinker cortexillin I
    • Ren, Y., Effler, J. C., Norstrom, M., Luo, T., Firtel, R. A., Iglesias, P. A., Rock, R. S., and Robinson, D. N. (2009). Mechanosensing through cooperative interactions between myosin II and the actin crosslinker cortexillin I. Curr. Biol. 19, 1421-1428.
    • (2009) Curr. Biol. , vol.19 , pp. 1421-1428
    • Ren, Y.1    Effler, J.C.2    Norstrom, M.3    Luo, T.4    Firtel, R.A.5    Iglesias, P.A.6    Rock, R.S.7    Robinson, D.N.8
  • 64
    • 0037184025 scopus 로고    scopus 로고
    • Polarization of myosin II heavy chain-protein kinase C in chemotaxing Dictyostelium cells
    • Rubin, H., and Ravid, S. (2002). Polarization of myosin II heavy chain-protein kinase C in chemotaxing Dictyostelium cells. J. Biol. Chem. 277, 36005-36008.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36005-36008
    • Rubin, H.1    Ravid, S.2
  • 65
    • 50049123401 scopus 로고    scopus 로고
    • Chemokines and leukocyte traffic
    • Sallusto, F., and Baggiolini, M. (2008). Chemokines and leukocyte traffic. Nat. Immunol. 9, 949-952.
    • (2008) Nat. Immunol. , vol.9 , pp. 949-952
    • Sallusto, F.1    Baggiolini, M.2
  • 66
    • 8444221934 scopus 로고    scopus 로고
    • Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement
    • Sasaki, A. T., Chun, C., Takeda, K., and Firtel, R. A. (2004). Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J. Cell Biol. 167, 505-518.
    • (2004) J. Cell Biol. , vol.167 , pp. 505-518
    • Sasaki, A.T.1    Chun, C.2    Takeda, K.3    Firtel, R.A.4
  • 69
    • 0031972805 scopus 로고    scopus 로고
    • Phosphorylation of the Dictyostelium myosin II heavy chain is necessary for maintaining cellular polarity and suppressing turning during chemotaxis
    • Stites, J., Wessels, D., Uhl, A., Egelhoff, T., Shutt, D., and Soll, D. R. (1998). Phosphorylation of the Dictyostelium myosin II heavy chain is necessary for maintaining cellular polarity and suppressing turning during chemotaxis. Cell Motil. Cytoskeleton 39, 31-51.
    • (1998) Cell Motil. Cytoskeleton , vol.39 , pp. 31-51
    • Stites, J.1    Wessels, D.2    Uhl, A.3    Egelhoff, T.4    Shutt, D.5    Soll, D.R.6
  • 70
    • 34247372469 scopus 로고    scopus 로고
    • Role of phosphatidylinositol 3-kinases in chemotaxis in Dictyostelium
    • Takeda, K., Sasaki, A. T., Ha, H., Seung, H. A., and Firtel, R. A. (2007). Role of phosphatidylinositol 3-kinases in chemotaxis in Dictyostelium. J. Biol. Chem. 282, 11874-11884.
    • (2007) J. Biol. Chem. , vol.282 , pp. 11874-11884
    • Takeda, K.1    Sasaki, A.T.2    Ha, H.3    Seung, H.A.4    Firtel, R.A.5
  • 72
    • 34548459788 scopus 로고    scopus 로고
    • Chemotaxis: Navigating by multiple signaling pathways
    • Van Haastert, P. J., and Veltman, D. M. (2007). Chemotaxis: navigating by multiple signaling pathways. Sci. STKE 2007, pe40.
    • (2007) Sci. STKE , vol.2007
    • Van Haastert, P.J.1    Veltman, D.M.2
  • 73
    • 33746648129 scopus 로고    scopus 로고
    • To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front
    • Van Keymeulen, A., Wong, K., Knight, Z. A., Govaerts, C., Hahn, K. M., Shokat, K. M., and Bourne, H. R. (2006). To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front. J. Cell Biol. 174, 437-445.
    • (2006) J. Cell Biol. , vol.174 , pp. 437-445
    • Van Keymeulen, A.1    Wong, K.2    Knight, Z.A.3    Govaerts, C.4    Hahn, K.M.5    Shokat, K.M.6    Bourne, H.R.7
  • 74
    • 33746225428 scopus 로고    scopus 로고
    • Regulation of PTEN function as a PIP3 gatekeeper through membrane interaction
    • Vazquez, F., and Devreotes, P. (2006). Regulation of PTEN function as a PIP3 gatekeeper through membrane interaction. Cell Cycle 5, 1523-1527. (Pubitemid 44091972)
    • (2006) Cell Cycle , vol.5 , Issue.14 , pp. 1523-1527
    • Vazquez, F.1    Devreotes, P.2
  • 75
    • 13744250304 scopus 로고    scopus 로고
    • Long-distance propagation of forces in a cell
    • Wang, N., and Suo, Z. (2005). Long-distance propagation of forces in a cell. Biochem. Biophys. Res. Comm. 328, 1133-1138.
    • (2005) Biochem. Biophys. Res. Comm. , vol.328 , pp. 1133-1138
    • Wang, N.1    Suo, Z.2
  • 76
    • 0033081026 scopus 로고    scopus 로고
    • Cytokinesis mediated through the recruitment of cortexillins into the cleavage furrow
    • Weber, I., Gerisch, G., Heizer, C., Murphy, J., Badelt, K., Stock, A., Schwartz, J. M., and Faix, J. (1999). Cytokinesis mediated through the recruitment of cortexillins into the cleavage furrow. EMBO J. 18, 586-594.
    • (1999) EMBO J. , vol.18 , pp. 586-594
    • Weber, I.1    Gerisch, G.2    Heizer, C.3    Murphy, J.4    Badelt, K.5    Stock, A.6    Schwartz, J.M.7    Faix, J.8
  • 78
    • 0023924075 scopus 로고
    • Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain
    • Wessels, D., Soll, D. R., Knecht, D., Loomis, W. F., De Lozanne, A., and Spudich, J. (1988). Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain. Dev. Biol. 128, 164-177.
    • (1988) Dev. Biol. , vol.128 , pp. 164-177
    • Wessels, D.1    Soll, D.R.2    Knecht, D.3    Loomis, W.F.4    De Lozanne, A.5    Spudich, J.6
  • 79
    • 67349209489 scopus 로고    scopus 로고
    • Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC
    • Wu, D., Asiedu, M., and Wei, Q. (2009). Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC. Oncogene 28, 2219-2230.
    • (2009) Oncogene , vol.28 , pp. 2219-2230
    • Wu, D.1    Asiedu, M.2    Wei, Q.3
  • 81
    • 0035313171 scopus 로고    scopus 로고
    • During multicellular migration, myosin ii serves a structural role independent of its motor function
    • Xu, X. S., Lee, E., Chen, T., Kuczmarski, E., Chisholm, R. L., and Knecht, D. A. (2001). During multicellular migration, myosin ii serves a structural role independent of its motor function. Dev. Biol. 232, 255-264.
    • (2001) Dev. Biol. , vol.232 , pp. 255-264
    • Xu, X.S.1    Lee, E.2    Chen, T.3    Kuczmarski, E.4    Chisholm, R.L.5    Knecht, D.A.6
  • 82
    • 0031670169 scopus 로고    scopus 로고
    • Spatiotemporal dynamics of actin concentration during cytokinesis and locomotion in Dictyostelium
    • Yumura, S., and Fukui, Y. (1998). Spatiotemporal dynamics of actin concentration during cytokinesis and locomotion in Dictyostelium. J. Cell Sci. 111, 2097-2108.
    • (1998) J. Cell Sci. , vol.111 , pp. 2097-2108
    • Yumura, S.1    Fukui, Y.2
  • 83
    • 24344452910 scopus 로고    scopus 로고
    • Multiple myosin II heavy chain kinases: Roles in filament assembly control and proper cytokinesis in Dictyostelium
    • Yumura, S., Yoshida, M., Betapudi, V., Licate, L. S., Iwadate, Y., Nagasaki, A., Uyeda, T. Q., and Egelhoff, T. T. (2005). Multiple myosin II heavy chain kinases: roles in filament assembly control and proper cytokinesis in Dictyostelium. Mol. Biol. Cell 16, 4256-4266.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4256-4266
    • Yumura, S.1    Yoshida, M.2    Betapudi, V.3    Licate, L.S.4    Iwadate, Y.5    Nagasaki, A.6    Uyeda, T.Q.7    Egelhoff, T.T.8
  • 84
    • 54149103045 scopus 로고    scopus 로고
    • Spatiotemporal regulation of Ras activity provides directional sensing
    • Zhang, S., Charest, P. G., and Firtel, R. A. (2008). Spatiotemporal regulation of Ras activity provides directional sensing. Curr. Biol. 18, 1587-1593.
    • (2008) Curr. Biol. , vol.18 , pp. 1587-1593
    • Zhang, S.1    Charest, P.G.2    Firtel, R.A.3


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