D-pinitol inhibits prostate cancer metastasis through inhibition of αVβ3 integrin by modulating FAK, c-Src and NF-κB pathways

International Journal of Molecular Sciences

Volumn 14, Issue 5, 2013, Pages 9790-9802

  Lin, Tien Huang ^a,b   Tan, Tzu Wei ^a,c   Tsai, Tsung Hsun ^b   Chen, Chi Cheng ^b   Hsieh, Teng Fu ^b   Lee, Shang Sen ^b   Liu, Hsin Ho ^b   Chen, Wen Chi ^a,d   Tang, Chih Hsin ^a,c,e  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b Buddhist Tzu Chi General Hospital Taichung Branch   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e ASIA UNIVERSITY   (Taiwan)

Author keywords

D pinitol; FAK; Integrin; Migration; Prostate cancer

Indexed keywords

CASPASE 3; DEXTRO PINITOL; FOCAL ADHESION KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INOSITOL DERIVATIVE; INTEGRIN; MESSENGER RNA; PROTEIN KINASE P60; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR; ANTINEOPLASTIC AGENT; CSK TYROSINE-PROTEIN KINASE; FOCAL ADHESION KINASE 1; INOSITOL; PINITOL; PROTEIN TYROSINE KINASE;

ARTICLE; CANCER CELL CULTURE; CELL INVASION; CELL MIGRATION; CELL SURFACE; CONCENTRATION RESPONSE; DRUG CYTOTOXICITY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MALE; METASTASIS INHIBITION; PROSTATE CANCER; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANALOGS AND DERIVATIVES; DRUG EFFECTS; IMMUNOLOGY; NEOPLASM METASTASIS; PATHOLOGY; PROSTATE; PROSTATIC NEOPLASMS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; FOCAL ADHESION KINASE 1; HUMANS; INOSITOL; INTEGRIN ALPHAVBETA3; MALE; NEOPLASM METASTASIS; NF-KAPPA B; PROSTATE; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84877697461     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14059790     Document Type: Article

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