-
1
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N, Levine B, Cuervo AM and Klionsky DJ: Autophagy fights disease through cellular self-digestion. Nature 451: 1069-1075, 2008.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
2
-
-
69349087479
-
Anti- And pro-tumor functions of autophagy
-
Morselli E, Galluzzi L, Kepp O, Vicencio JM, Criollo A, Maiuri MC and Kroemer G: Anti- and pro-tumor functions of autophagy. Biochim Biophys Acta 1793: 1524-1532, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 1524-1532
-
-
Morselli, E.1
Galluzzi, L.2
Kepp, O.3
Vicencio, J.M.4
Criollo, A.5
Maiuri, M.C.6
Kroemer, G.7
-
3
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D and Weinberg RA: Hallmarks of cancer: The next generation. Cell 144: 646-674, 2011.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X, Yu J, Bhagat G, Furuya N, Furuya N, Hibshoosh H, Troxel A, Rosen J, Eskelinen EL, Mizushima N, Ohsumi Y, Cattoretti G and Levine B: Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 112: 1809-2180, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 1809-2180
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Furuya, N.5
Hibshoosh, H.6
Troxel, A.7
Rosen, J.8
Eskelinen, E.L.9
Mizushima, N.10
Ohsumi, Y.11
Cattoretti, G.12
Levine, B.13
-
6
-
-
79955377420
-
Autophagy-deficient mice develop multiple liver tumors
-
Takamura A, Komatsu M, Hara T, Sakamoto A, Kishi C, Waguri S, Eishi Y, Hino O, Tanaka and Mizushima N: Autophagy-deficient mice develop multiple liver tumors. Genes Dev 25: 795-800, 2011.
-
(2011)
Genes Dev
, vol.25
, pp. 795-800
-
-
Takamura, A.1
Komatsu, M.2
Hara, T.3
Sakamoto, A.4
Kishi, C.5
Waguri, S.6
Eishi, Y.7
Tanaka, H.O.8
Mizushima, N.9
-
7
-
-
34547132328
-
Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
-
Mariño G, Salvador-Montoliu N, Fueyo A, Knecht E, Mizushima N and López-Otín C: Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J Biol Chem 282: 18573-18583, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 18573-18583
-
-
Mariño, G.1
Salvador-Montoliu, N.2
Fueyo, A.3
Knecht, E.4
Mizushima, N.5
López-Otín, C.6
-
8
-
-
80052350645
-
Potential role of p62 in tumor development
-
Komatsu M: Potential role of p62 in tumor development. Autophagy 7: 1088-1090, 2011.
-
(2011)
Autophagy
, vol.7
, pp. 1088-1090
-
-
Komatsu, M.1
-
9
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G, Mukherjee C, Shi Y, Gélinas C, Fan Y, Nelson DA, Jin San and White E: Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 10: 51-64, 2006.
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
Bray, K.4
Anderson, D.5
Chen, G.6
Mukherjee, C.7
Shi, Y.8
Gélinas, C.9
Fan, Y.10
Nelson, D.A.11
San, J.12
White, E.13
-
10
-
-
33846244269
-
Role of autophagy in cancer: Management of metabolic stress
-
Jin S and White E: Role of autophagy in cancer: Management of metabolic stress. Autophagy 3: 28-31, 2007.
-
(2007)
Autophagy
, vol.3
, pp. 28-31
-
-
Jin, S.1
White, E.2
-
11
-
-
76049100577
-
HIF-1: Upstream and downstream of cancer metabolism
-
Semenza GL: HIF-1: upstream and downstream of cancer metabolism. Curr Opin Genet Dev 20: 51-56, 2010.
-
(2010)
Curr Opin Genet Dev
, vol.20
, pp. 51-56
-
-
Semenza, G.L.1
-
12
-
-
20144381544
-
Essential roles of ATG5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death
-
Pyo JO, Jang MH, Kwon YK, Lee HJ, Jun JI, Woo HN, Cho DH, Choi B, Lee H, Kim JH, Mizushima N, Oshumi Y and Jung YK: Essential roles of ATG5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem 280: 20722-20729, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 20722-20729
-
-
Pyo, J.O.1
Jang, M.H.2
Kwon, Y.K.3
Lee, H.J.4
Jun, J.I.5
Woo, H.N.6
Cho, D.H.7
Choi, B.8
Lee, H.9
Kim, J.H.10
Mizushima, N.11
Oshumi, Y.12
Jung, Y.K.13
-
13
-
-
33749162486
-
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
-
Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L, Brunner T and Simon HU: Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 8: 1124-1132, 2006.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1124-1132
-
-
Yousefi, S.1
Perozzo, R.2
Schmid, I.3
Ziemiecki, A.4
Schaffner, T.5
Scapozza, L.6
Brunner, T.7
Simon, H.U.8
-
14
-
-
77954274211
-
Up-regulation of SPRR3 promotes colorectal tumorigenesis
-
Cho DH, Jo YK, Roh SA, Na YS, Kim TW, Jang SJ, Kim YS, Kim JC: Up-regulation of SPRR3 promotes colorectal tumorigenesis. Mol Med 16: 271-277, 2010.
-
(2010)
Mol Med
, vol.16
, pp. 271-277
-
-
Cho, D.H.1
Jo, Y.K.2
Roh, S.A.3
Na, Y.S.4
Kim, T.W.5
Jang, S.J.6
Kim, Y.S.7
Kim, J.C.8
-
15
-
-
79957883170
-
The multiple roles of autophagy in cancer
-
Rosenfeldt MT and Ryan KM: The multiple roles of autophagy in cancer. Carcinogenesis 32: 955-963, 2011.
-
(2011)
Carcinogenesis
, vol.32
, pp. 955-963
-
-
Rosenfeldt, M.T.1
Ryan, K.M.2
-
16
-
-
80053634368
-
The dynamic nature of autophagy in cancer
-
Kimmelman AC: The dynamic nature of autophagy in cancer. Genes Dev 25: 1999-2010, 2011.
-
(2011)
Genes Dev
, vol.25
, pp. 1999-2010
-
-
Kimmelman, A.C.1
-
17
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H and Levine B: Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402: 672-676, 1999.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
Levine, B.7
-
18
-
-
77952272127
-
Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors
-
Li Z, Chen B, Wu Y, Jin F, Xia Y and Liu X: Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors. BMC Cancer 10: 98-110, 2010.
-
(2010)
BMC Cancer
, vol.10
, pp. 98-110
-
-
Li, Z.1
Chen, B.2
Wu, Y.3
Jin, F.4
Xia, Y.5
Liu, X.6
-
19
-
-
33344454909
-
Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma
-
Pasqualucci L, Compagno M, Houldsworth J, Monti S, Grunn A, Nandula SV, Aster JC, Murty VV, Shipp MA and Dalla-Favera R: Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma. J Exp Med 203: 311-317, 2006.
-
(2006)
J Exp Med
, vol.203
, pp. 311-317
-
-
Pasqualucci, L.1
Compagno, M.2
Houldsworth, J.3
Monti, S.4
Grunn, A.5
Nandula, S.V.6
Aster, J.C.7
Murty, V.V.8
Shipp, M.A.9
Dalla-Favera, R.10
-
20
-
-
75049085554
-
BLIMP-1 is a tumor suppressor gene in lymphoid malignancies
-
Hangaishi A and Kurokawa M: BLIMP-1 is a tumor suppressor gene in lymphoid malignancies. Int J Hematol 91: 46-53, 2010.
-
(2010)
Int J Hematol
, vol.91
, pp. 46-53
-
-
Hangaishi, A.1
Kurokawa, M.2
-
21
-
-
67349138549
-
Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies
-
Iqbal J, Kucuk C, Deleeuw RJ, Srivastava G, Tam W, Geng H, Klinkebiel D, Christman JK, Patel K, Cao K, Shen L, Dybkaer K, Tsui IF, Ali H, Shimizu N, Au WY, Lam WL and Chan WC: Genomic analyses reveal global functional alterations that promote tumor growth and novel tumor suppressor genes in natural killer-cell malignancies. Leukemia 23: 1139-1151, 2009.
-
(2009)
Leukemia
, vol.23
, pp. 1139-1151
-
-
Iqbal, J.1
Kucuk, C.2
Deleeuw, R.J.3
Srivastava, G.4
Tam, W.5
Geng, H.6
Klinkebiel, D.7
Christman, J.K.8
Patel, K.9
Cao, K.10
Shen, L.11
Dybkaer, K.12
Tsui, I.F.13
Ali, H.14
Shimizu, N.15
Au, W.Y.16
Lam, W.L.17
Chan, W.C.18
-
22
-
-
33644846509
-
Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction?
-
Baylin SB and Ohm JE: Epigenetic gene silencing in cancer-a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 6: 107-116, 2006.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 107-116
-
-
Baylin, S.B.1
Ohm, J.E.2
-
23
-
-
79953773106
-
IKK-dependent, NF-κB-independent control of autophagic gene expression
-
Comb WC, Cogswell P, Sitcheran R and Baldwin AS: IKK-dependent, NF-κB-independent control of autophagic gene expression. Oncogene 30: 1727-1732, 2011.
-
(2011)
Oncogene
, vol.30
, pp. 1727-1732
-
-
Comb, W.C.1
Cogswell, P.2
Sitcheran, R.3
Baldwin, A.S.4
-
24
-
-
0442323562
-
NF-kappaB: Tumor promoter or suppressor?
-
Perkins ND: NF-kappaB: Tumor promoter or suppressor? Trends Cell Biol 14: 64-69, 2004.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 64-69
-
-
Perkins, N.D.1
-
25
-
-
34248233678
-
Comparison of outcomes following ileostomy versus colostomy for defunctioning colorectal anastomoses
-
Tilney HS, Sains PS, Lovegrove RE, Reese GE, Heriot AG and Tekkis PP: Comparison of outcomes following ileostomy versus colostomy for defunctioning colorectal anastomoses. World J Surg 31: 1142-1151, 2007.
-
(2007)
World J Surg
, vol.31
, pp. 1142-1151
-
-
Tilney, H.S.1
Sains, P.S.2
Lovegrove, R.E.3
Reese, G.E.4
Heriot, A.G.5
Tekkis, P.P.6
-
26
-
-
38349107307
-
What is the role for the circumferential margin in the modern treatment of rectal cancer?
-
Nagtegaal ID and Quirke P: What is the role for the circumferential margin in the modern treatment of rectal cancer? J Clin Oncol 26: 303-312, 2008.
-
(2008)
J Clin Oncol
, vol.26
, pp. 303-312
-
-
Nagtegaal, I.D.1
Quirke, P.2
-
27
-
-
77956381205
-
Severe tumor budding is a risk factor for lateral lymph node metastasis in early rectal cancers
-
Homma Y, Hamano T, Otsuki Y, Shimizu S, Kobayashi H and Kobayashi Y: Severe tumor budding is a risk factor for lateral lymph node metastasis in early rectal cancers. J Surg Oncol 102: 230-234, 2010.
-
(2010)
J Surg Oncol
, vol.102
, pp. 230-234
-
-
Homma, Y.1
Hamano, T.2
Otsuki, Y.3
Shimizu, S.4
Kobayashi, H.5
Kobayashi, Y.6
-
29
-
-
78651241644
-
Colorectal cancer molecular biology moves into clinical practice
-
Pritchard CC and Grady WM: Colorectal cancer molecular biology moves into clinical practice. Gut 60: 116-129, 2011.
-
(2011)
Gut
, vol.60
, pp. 116-129
-
-
Pritchard, C.C.1
Grady, W.M.2
|