-
1
-
-
79959966626
-
Clofarabine 5'-di and-triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit
-
Aye Y., Stubbe J.: Clofarabine 5'-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit. Proc. Natl. Acad. Sci. USA, 2011;108:9815-9820
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 9815-9820
-
-
Aye, Y.1
Stubbe, J.2
-
2
-
-
84867884697
-
Effect of adenosine modified with a boron cluster pharmacophore on reactive oxygen species production by human neutrophils
-
Bednarska K., Olejniczak A. B., Piskala A., Klink M., Sulowska Z., Lesnikowski Z. J.: Effect of adenosine modified with a boron cluster pharmacophore on reactive oxygen species production by human neutrophils. Bioorg. Med. Chem., 2012;20:6621-6629
-
(2012)
Bioorg. Med. Chem.
, vol.20
, pp. 6621-6629
-
-
Bednarska, K.1
Olejniczak, A.B.2
Piskala, A.3
Klink, M.4
Sulowska, Z.5
Lesnikowski, Z.J.6
-
3
-
-
49649091999
-
Modulation of murine dendritic cell function by adenine nucleotides and adenosine: Involvement of the A (2B) receptor
-
Ben Addi A., Lefort A., Hua X., Libert F., Communi D., Ledent C., Macours P., Tilley S. L., Boeynaems J. M., Robaye B.: Modulation of murine dendritic cell function by adenine nucleotides and adenosine: involvement of the A (2B) receptor. Eur. J. Immunol., 2008;38:1610-1620
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 1610-1620
-
-
Ben Addi, A.1
Lefort, A.2
Hua, X.3
Libert, F.4
Communi, D.5
Ledent, C.6
Macours, P.7
Tilley, S.L.8
Boeynaems, J.M.9
Robaye, B.10
-
4
-
-
34547098277
-
Expression of ectonucleotidase CD39 by Foxp3 (+) Treg cells: Hydrolysis of extracellular ATP and immune suppression
-
Borsellino G., Kleinewietfeld M., Di Mitri D., Sternjak A., Diamantini A., Giometto R., Höpner S., Centonze D., Bernardi G., Dell'Acqua M. L., Rossini P. M., Battistini L., Rötzschke O., Falk K.: Expression of ectonucleotidase CD39 by Foxp3 (+) Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood, 2007;110:1225-1232
-
(2007)
Blood
, vol.110
, pp. 1225-1232
-
-
Borsellino, G.1
Kleinewietfeld, M.2
Di Mitri, D.3
Sternjak, A.4
Diamantini, A.5
Giometto, R.6
Höpner, S.7
Centonze, D.8
Bernardi, G.9
Dell'Acqua, M.L.10
Rossini, P.M.11
Battistini, L.12
Rötzschke, O.13
Falk, K.14
-
5
-
-
38049083924
-
5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A (1) adenosine receptor agonists: Affinity, efficacy, and selectivity for A (1) receptor from different species
-
Cappellacci L., Franchetti P., Vita P., Petrelli R., Lavecchia A., Costa B., Spinetti F., Martini C., Klotz K. N., Grifantini M.: 5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A (1) adenosine receptor agonists: Affinity, efficacy, and selectivity for A (1) receptor from different species. Bioorg. Med. Chem., 2008;16:336-353
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 336-353
-
-
Cappellacci, L.1
Franchetti, P.2
Vita, P.3
Petrelli, R.4
Lavecchia, A.5
Costa, B.6
Spinetti, F.7
Martini, C.8
Klotz, K.N.9
Grifantini, M.10
-
6
-
-
79953165649
-
6- disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents
-
6- disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents. Eur. J. Med. Chem., 2011;46:1499-1504
-
(2011)
Eur. J. Med. Chem.
, vol.46
, pp. 1499-1504
-
-
Cappellacci, L.1
Petrelli, R.2
Franchetti, P.3
Vita, P.4
Kusumanchi, P.5
Kumar, M.6
Jayaram, H.N.7
Zhou, B.8
Yen, Y.9
Grifantini, M.10
-
7
-
-
79851507336
-
2'-Deoxy-2'-α-C-(hydroxymethyl) adenosine as potential anti-HCV agent
-
Chavain N., Herdewijn P.: 2'-Deoxy-2'-α-C-(hydroxymethyl) adenosine as potential anti-HCV agent. Eur. J. Org. Chem., 2011;2011:1140-1147
-
(2011)
Eur. J. Org. Chem.
, vol.2011
, pp. 1140-1147
-
-
Chavain, N.1
Herdewijn, P.2
-
8
-
-
48449098290
-
Bis (sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: Inhibition of inosine monophosphate dehydrogenase
-
Chen L., Petrelli R., Olesiak M., Wilson D. J., Labello N. P., Pankiewicz K. W.: Bis (sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase. Bioorg. Med. Chem., 2008;16:7462-7469
-
(2008)
Bioorg. Med. Chem.
, vol.16
, pp. 7462-7469
-
-
Chen, L.1
Petrelli, R.2
Olesiak, M.3
Wilson, D.J.4
Labello, N.P.5
Pankiewicz, K.W.6
-
9
-
-
0028960866
-
Detection of single-strand breaks and formamidopyrimidine-dna glycosylase-sensitive sites in dna of cultured human fibroblasts
-
Czene S, Harms-Ringdahl M.: Detection of single-strand breaks and formamidopyrimidine-dna glycosylase-sensitive sites in dna of cultured human fibroblasts. Mutat. Res., 1995;336:235-242
-
(1995)
Mutat. Res.
, vol.336
, pp. 235-242
-
-
Czene, S.1
Harms-Ringdahl, M.2
-
10
-
-
34250351459
-
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
-
Deaglio S., Dwyer K. M., Gao W., Fredman D., Usheva A., Reat A., Chen J. F., Enjyoji K., Linden J., Oukka M., Kuchroo V. K., Strom T. B., Robson S. C.: Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J. Exp. Med., 2007;204:1257-1265
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1257-1265
-
-
Deaglio, S.1
Dwyer, K.M.2
Gao, W.3
Fredman, D.4
Usheva, A.5
Reat, A.6
Chen, J.F.7
Enjyoji, K.8
Linden, J.9
Oukka, M.10
Kuchroo, V.K.11
Strom, T.B.12
Robson, S.C.13
-
11
-
-
78650408267
-
Diadenosine 5', 5"-(boranated) polyphosphonate analogues as selective nucleotide pyrophosphatase/phosphodiesterase inhibitors
-
Eliahu S., Lecka J., Reiser G., Haas M., Bigonnesse F., Levesque S. A., Pelletier J., Sevigny J., Fischer B.: Diadenosine 5', 5"-(boranated) polyphosphonate analogues as selective nucleotide pyrophosphatase/ phosphodiesterase inhibitors. J. Med. Chem., 2010;53:8485-8497
-
(2010)
J. Med. Chem.
, vol.53
, pp. 8485-8497
-
-
Eliahu, S.1
Lecka, J.2
Reiser, G.3
Haas, M.4
Bigonnesse, F.5
Levesque, S.A.6
Pelletier, J.7
Sevigny, J.8
Fischer, B.9
-
12
-
-
79958760220
-
Synthesis and antiviral activity of cyclopropyl-spirocarbocyclic adenosine, (4R, 5S, 6R, 7R)-4-(6-amino-9H-purin-9-yl)-7-(hydroxymethyl) spiro [2. 4] heptane-5, 6-diol against hepatitis C virus
-
Gadthula S., Rawal R. K., Sharon A., Wu D., Korba B., Chu C. K.: Synthesis and antiviral activity of cyclopropyl-spirocarbocyclic adenosine, (4R, 5S, 6R, 7R)-4-(6-amino-9H-purin-9-yl)-7-(hydroxymethyl) spiro [2. 4] heptane-5, 6-diol against hepatitis C virus. Bioorg. Med. Chem. Lett., 2011;21:3982-3985
-
(2011)
Bioorg. Med. Chem. Lett.
, vol.21
, pp. 3982-3985
-
-
Gadthula, S.1
Rawal, R.K.2
Sharon, A.3
Wu, D.4
Korba, B.5
Chu, C.K.6
-
13
-
-
79955870587
-
Inhibitors of hepatitis C virus-current standards and status of investigations
-
Godzik P., Komorowski M., Cielecka-Kuszyk J., Madalinski K.: Inhibitors of hepatitis C virus-current standards and status of investigations. Przegl. Epidemiol., 2010;64:473-478
-
(2010)
Przegl. Epidemiol.
, vol.64
, pp. 473-478
-
-
Godzik, P.1
Komorowski, M.2
Cielecka-Kuszyk, J.3
Madalinski, K.4
-
14
-
-
0026456852
-
The measurement of oxidative damage to DNA by HPLC and GC/MS techniques
-
Halliwell B., Dizdaroglu M.: The measurement of oxidative damage to DNA by HPLC and GC/MS techniques. Free Radic. Res. Commun., 1992;16:75-87
-
(1992)
Free Radic. Res. Commun.
, vol.16
, pp. 75-87
-
-
Halliwell, B.1
Dizdaroglu, M.2
-
15
-
-
84865640480
-
Adenosine A2A antagonists in Parkinson's disease: What's next?
-
Hickey P., Stacy M.: Adenosine A2A antagonists in Parkinson's disease: what's next? Curr. Neurol. Neurosci. Rep., 2012;12:376-385
-
(2012)
Curr. Neurol. Neurosci. Rep.
, vol.12
, pp. 376-385
-
-
Hickey, P.1
Stacy, M.2
-
16
-
-
79251469106
-
The role of adenosine receptor agonists in regulation of hematopoiesis
-
Hofer M., Pospisil M., Weiterowa L., Hoferova Z.: The role of adenosine receptor agonists in regulation of hematopoiesis. Molecules, 2011;16:675-685
-
(2011)
Molecules
, vol.16
, pp. 675-685
-
-
Hofer, M.1
Pospisil, M.2
Weiterowa, L.3
Hoferova, Z.4
-
17
-
-
80051826503
-
Mutagenicity of secondary oxidation products of 8-oxo-7, 8-dihydro-2'-deoxyguanosine 5'-triphosphate (8-hydroxy-2'-deoxyguanosine 5'-triphosphate)
-
Hori M., Suzuki T., Minakawa N., Matsuda A., Harashima H., Kamiya H.: Mutagenicity of secondary oxidation products of 8-oxo-7, 8-dihydro-2'- deoxyguanosine 5'-triphosphate (8-hydroxy-2'-deoxyguanosine 5'-triphosphate). Mutat. Res. - Fund. Mol. M, 2011;714:11-16
-
(2011)
Mutat. Res. - Fund. Mol. M
, vol.714
, pp. 11-16
-
-
Hori, M.1
Suzuki, T.2
Minakawa, N.3
Matsuda, A.4
Harashima, H.5
Kamiya, H.6
-
18
-
-
79953776648
-
Coumarin-purine ribofuranoside conjugates as new agents against hepatitis C virus
-
Hwu J. R., Lin S. Y., Tsay S. C., De Clercq E., Leyssen P., Neyts J.: Coumarin-purine ribofuranoside conjugates as new agents against hepatitis C virus. J. Med. Chem., 2011;54:2114-2126
-
(2011)
J. Med. Chem.
, vol.54
, pp. 2114-2126
-
-
Hwu, J.R.1
Lin, S.Y.2
Tsay, S.C.3
De Clercq, E.4
Leyssen, P.5
Neyts, J.6
-
19
-
-
0035038033
-
Sugar-modified nucleosides in past 10 years, a review
-
Ichikawa E., Kato K.: Sugar-modified nucleosides in past 10 years, a review. Curr. Med. Chem., 2001;8:385-423
-
(2001)
Curr. Med. Chem.
, vol.8
, pp. 385-423
-
-
Ichikawa, E.1
Kato, K.2
-
20
-
-
33644770260
-
Adenosine receptors as therapeutic targets
-
Jacobson K., Gao Z. G.: Adenosine receptors as therapeutic targets. Nat. Rev. Drug Discov, 2006;5:247-264
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 247-264
-
-
Jacobson, K.1
Gao, Z.G.2
-
21
-
-
80051527677
-
Modified nucleosides as selective modulators of adenosine receptors for therapeutic use
-
Red. Herdewijn P. D., Wiley-VCH, Weinheim
-
Jacobson K. Joshi B., Wang B., Klutz A., Kim Y., Ivanov A.: Modified nucleosides as selective modulators of adenosine receptors for therapeutic use. W: Modified Nucleosides: in Biochemistry, Biotechnology and Medicine. Red. Herdewijn P. D., Wiley-VCH, Weinheim, 2008, 433-449
-
(2008)
Modified Nucleosides: In Biochemistry, Biotechnology and Medicine
, pp. 433-449
-
-
Jacobson, K.1
Joshi, B.2
Wang, B.3
Klutz, A.4
Kim, Y.5
Ivanov, A.6
-
22
-
-
0034730498
-
A novel pharmacological approach to treating cardiac ischemia. Binary conjugates of A1 and A3 adenosine receptor agonists
-
Jacobson K. A., Xie R. Y., Young L., Chang L., Liang B. T.: A novel pharmacological approach to treating cardiac ischemia. Binary conjugates of A1 and A3 adenosine receptor agonists. J. Biol. Chem., 2000;275:30272-30279
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30272-30279
-
-
Jacobson, K.A.1
Xie, R.Y.2
Young, L.3
Chang, L.4
Liang, B.T.5
-
23
-
-
79957465550
-
Mechanism of action of pentostatin and cladribine in hairy cell leukemia
-
Johnston J. B.: Mechanism of action of pentostatin and cladribine in hairy cell leukemia. Leuk. Lymphoma, 2011;52, Suppl. 2:43-45
-
(2011)
Leuk. Lymphoma
, vol.52
, Issue.SUPPL. 2
, pp. 43-45
-
-
Johnston, J.B.1
-
24
-
-
84861017463
-
Rapid measurement of 8-oxo-7, 8-dihydro-2 '-deoxyguanosine in human biological matrices using ultra-high-performance liquid chromatography-tandem mass spectrometry
-
Lam P. M., Mistry V., Marczylo T. H., Konje J. C., Evans M. D., Cooke M. S.: Rapid measurement of 8-oxo-7, 8-dihydro-2 '-deoxyguanosine in human biological matrices using ultra-high-performance liquid chromatography-tandem mass spectrometry. Free Radic. Biol. Med., 2012;52:2057-2063
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 2057-2063
-
-
Lam, P.M.1
Mistry, V.2
Marczylo, T.H.3
Konje, J.C.4
Evans, M.D.5
Cooke, M.S.6
-
25
-
-
33646550489
-
Pharmacological and clinical studies on purine nucleoside analogs - New anticancer agents
-
Lech-Maranda E., Korycka A., Robak T.: Pharmacological and clinical studies on purine nucleoside analogs - new anticancer agents. Mini Rev. Med. Chem., 2006;6:575-581
-
(2006)
Mini Rev. Med. Chem.
, vol.6
, pp. 575-581
-
-
Lech-Maranda, E.1
Korycka, A.2
Robak, T.3
-
26
-
-
79957519264
-
Synthesis and binding affinity of homologated adenosine analogues as A3 adenosine receptor ligands
-
Lee W. H., Choi W. J. Jacobson K. A., Jeong L. S.: Synthesis and binding affinity of homologated adenosine analogues as A3 adenosine receptor ligands. Bull. Korean Chem. Soc, 2011;32:1620-1624
-
(2011)
Bull. Korean Chem. Soc
, vol.32
, pp. 1620-1624
-
-
Lee, W.H.1
Choi, W.J.2
Jacobson, K.A.3
Jeong, L.S.4
-
27
-
-
79959228146
-
Design, synthesis, and evaluation of 2-diethanolamino-4, 8-diheptamethyleneimino-2-(N-aminoethyl-N-ethanol amino)-6-(N, N-diethanolamino) pyrimido [5, 4-d]pyrimidine-fluorescein (8MDP-fluor), as a novel equilibrative nucleoside transporter probe
-
Lin W., Buolamwini K.: Design, synthesis, and evaluation of 2-diethanolamino-4, 8-diheptamethyleneimino-2-(N-aminoethyl-N-ethanol amino)-6-(N, N-diethanolamino) pyrimido [5, 4-d]pyrimidine-fluorescein (8MDP-fluor), as a novel equilibrative nucleoside transporter probe. Bioconjug. Chem., 2011;22:1221-1227
-
(2011)
Bioconjug. Chem.
, vol.22
, pp. 1221-1227
-
-
Lin, W.1
Buolamwini, K.2
-
28
-
-
0038243600
-
Intravenous adenosine alleviates neuropathic pain: A double blind placebo controlled crossover trial using an enriched enrolment design
-
Lynch M. E., Clark A. J., Sawynok J.: Intravenous adenosine alleviates neuropathic pain: a double blind placebo controlled crossover trial using an enriched enrolment design. Pain, 2003;103:111-117
-
(2003)
Pain
, vol.103
, pp. 111-117
-
-
Lynch, M.E.1
Clark, A.J.2
Sawynok, J.3
-
29
-
-
72049130583
-
Design, synthesis and biological evaluation of a bivalent mu opiate and adenosine A1 receptor antagonist
-
Mathew S. C., Ghosh N., By Y., Berthault A., Virolleaud M. A., Carrega L., Chouraqui G., Commeiras L., Condo J., Attolini M., Gaudel-Siri A., Ruf J., Parrain J. L., Rodriguez J., Guieu R.: Design, synthesis and biological evaluation of a bivalent mu opiate and adenosine A1 receptor antagonist. Bioorg. Med. Chem. Lett., 2009;19:6736-6739
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 6736-6739
-
-
Mathew, S.C.1
Ghosh, N.2
By, Y.3
Berthault, A.4
Virolleaud, M.A.5
Carrega, L.6
Chouraqui, G.7
Commeiras, L.8
Condo, J.9
Attolini, M.10
Gaudel-Siri, A.11
Ruf, J.12
Parrain, J.L.13
Rodriguez, J.14
Guieu, R.15
-
30
-
-
78650151809
-
Synthesis of cyclic adenosine 5'-diphosphate ribose analogues: A C2' endo/syn "southern" ribose confirmation underlies activity at the sea urchin cADPR receptor
-
Moreau C, Ashamu G. A., Bailey V. C., Galione A., Guse A. H., Potter B. V.: Synthesis of cyclic adenosine 5'-diphosphate ribose analogues: a C2' endo/syn "southern" ribose confirmation underlies activity at the sea urchin cADPR receptor. Org. Biomol. Chem., 2011;9:278-290
-
(2011)
Org. Biomol. Chem.
, vol.9
, pp. 278-290
-
-
Moreau, C.1
Ashamu, G.A.2
Bailey, V.C.3
Galione, A.4
Guse, A.H.5
Potter, B.V.6
-
31
-
-
8144226085
-
Boranophosphate salts as an excellent mimic of phosphate salts: Preparation, characterization, and properties
-
Nahum V., Fischer B.: Boranophosphate salts as an excellent mimic of phosphate salts: preparation, characterization, and properties. Eur. J. Inorg. Chem., 2004;2004:4124-4131
-
(2004)
Eur. J. Inorg. Chem.
, vol.2004
, pp. 4124-4131
-
-
Nahum, V.1
Fischer, B.2
-
33
-
-
0037204010
-
Novel mycophenolic adenine bis (phosphonate) analogues as potential differentiation agents against human leukemia
-
Pankiewicz K. W., Lesiak-Watanabe K. B., Watanabe K. A., Patterson S. E., Jayaram H. N., Yalowitz J. A., Miller M. D., Seidman M., Majumdar A., Prehna G., Goldstein B. M.: Novel mycophenolic adenine bis (phosphonate) analogues as potential differentiation agents against human leukemia. J. Med. Chem., 2002;45:703-712
-
(2002)
J. Med. Chem.
, vol.45
, pp. 703-712
-
-
Pankiewicz, K.W.1
Lesiak-Watanabe, K.B.2
Watanabe, K.A.3
Patterson, S.E.4
Jayaram, H.N.5
Yalowitz, J.A.6
Miller, M.D.7
Seidman, M.8
Majumdar, A.9
Prehna, G.10
Goldstein, B.M.11
-
34
-
-
49749093968
-
Synthesis of 3 '-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents
-
Pei X., Choi W. J., Kim Y. M., Zhao L. X., Jeong L. S.: Synthesis of 3 '-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents. Arch. Pharmacol. Res., 2008;31:843-849
-
(2008)
Arch. Pharmacol. Res.
, vol.31
, pp. 843-849
-
-
Pei, X.1
Choi, W.J.2
Kim, Y.M.3
Zhao, L.X.4
Jeong, L.S.5
-
35
-
-
31544467281
-
Recent advances in studies on biochemical and structural properties of equilibrative and concentrative nucleoside transporters
-
Podgórska M., Kocbuch K., Pawełczyk T.: Recent advances in studies on biochemical and structural properties of equilibrative and concentrative nucleoside transporters. Acta Biochim. Pol., 2005;52:749-758
-
(2005)
Acta Biochim. Pol.
, vol.52
, pp. 749-758
-
-
Podgórska, M.1
Kocbuch, K.2
Pawełczyk, T.3
-
36
-
-
84867575872
-
Synthesis and in vitro antitumour screening of 2-(β-d-xylofuranosyl) thiazole-4-carboxamide and two novel tiazofurin analogues with substituted tetrahydrofurodioxol moiety as a sugar mimic
-
Popsavin M., Spaić S., Svirčev M., Kojić V., Bogdanović G., Popsavin V.: Synthesis and in vitro antitumour screening of 2-(β-d-xylofuranosyl) thiazole-4-carboxamide and two novel tiazofurin analogues with substituted tetrahydrofurodioxol moiety as a sugar mimic. Bioorg. Med. Chem. Lett., 2012;22:6700-6704
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 6700-6704
-
-
Popsavin, M.1
Spaić, S.2
Svirčev, M.3
Kojić, V.4
Bogdanović, G.5
Popsavin, V.6
-
37
-
-
0031833150
-
Adenosine receptors: New opportunities for future drugs
-
Poulsen S. A., Quinn R. J.: Adenosine receptors: new opportunities for future drugs. Bioorg. Med. Chem., 1998;6:619-641
-
(1998)
Bioorg. Med. Chem.
, vol.6
, pp. 619-641
-
-
Poulsen, S.A.1
Quinn, R.J.2
-
38
-
-
79952138727
-
Adenosine modulates Toll-like receptor function: Basic mechanisms and translational opportunities
-
Power Coombs M. R., Belderbos M. E., Gallington L. C., Bont L., Levy O.: Adenosine modulates Toll-like receptor function: basic mechanisms and translational opportunities. Expert Rev. Anti Infect. Ther., 2011;9:261-269
-
(2011)
Expert Rev. Anti Infect. Ther.
, vol.9
, pp. 261-269
-
-
Power Coombs, M.R.1
Belderbos, M.E.2
Gallington, L.C.3
Bont, L.4
Levy, O.5
-
39
-
-
50549090633
-
Adenosine-oligoarginine conjugate, a novel bisubstrate inhibitor, effectively dissociates the actin cytoskeleton
-
Raagel H., Lust M., Uri A., Pooga M.: Adenosine-oligoarginine conjugate, a novel bisubstrate inhibitor, effectively dissociates the actin cytoskeleton. FEBS Lett., 2008;275:3608-3624
-
(2008)
FEBS Lett.
, vol.275
, pp. 3608-3624
-
-
Raagel, H.1
Lust, M.2
Uri, A.3
Pooga, M.4
-
40
-
-
0028889564
-
Determination of 8-oxoguanine in dna by gas-chromatography mass-spectrometry and hplc-electrochemical detection - Overestimation of the background level of the oxidized base by the gas-chromatography mass-spectrometry assay
-
Ravanat J. L., Turesky R. J., Gremaud E., Trudel L. J., Stadler R. H.: Determination of 8-oxoguanine in dna by gas-chromatography mass-spectrometry and hplc-electrochemical detection - overestimation of the background level of the oxidized base by the gas-chromatography mass-spectrometry assay. Chem. Res. Toxicol., 1995;8:1039-1045
-
(1995)
Chem. Res. Toxicol.
, vol.8
, pp. 1039-1045
-
-
Ravanat, J.L.1
Turesky, R.J.2
Gremaud, E.3
Trudel, L.J.4
Stadler, R.H.5
-
41
-
-
23844481419
-
Purine nucleoside analogues for the treatment of hematological malignancies: Pharmacology and clinical applications
-
Robak T., Korycka A., Kasznicki M., Wrzesien-Kus A., Smolewski P.: Purine nucleoside analogues for the treatment of hematological malignancies: pharmacology and clinical applications. Curr. Cancer Drug Tar., 2005;5:421-444
-
(2005)
Curr. Cancer Drug Tar.
, vol.5
, pp. 421-444
-
-
Robak, T.1
Korycka, A.2
Kasznicki, M.3
Wrzesien-Kus, A.4
Smolewski, P.5
-
42
-
-
63449116519
-
Current status o folder and new purine nucleoside analogues in the treatment of lymphoproliferative diseases
-
Robak T., Korycka A., Lech-Maranda E., Robak P.: Current status o folder and new purine nucleoside analogues in the treatment of lymphoproliferative diseases. Molecules, 2009;14:1183-1226
-
(2009)
Molecules
, vol.14
, pp. 1183-1226
-
-
Robak, T.1
Korycka, A.2
Lech-Maranda, E.3
Robak, P.4
-
43
-
-
80051495803
-
Therapeutic potential of adenosine analogues and conjugates
-
Samsel M., Dzierzbicka K.: Therapeutic potential of adenosine analogues and conjugates. Pharmacol. Rep., 2011;63:601-617
-
(2011)
Pharmacol. Rep.
, vol.63
, pp. 601-617
-
-
Samsel, M.1
Dzierzbicka, K.2
-
44
-
-
0025981359
-
Insertion of specific bases during DNA-synthesis past the oxidation-damaged base 8-oxoDG
-
Shibutani S., Takeshita M., Grollaman A. P.: Insertion of specific bases during DNA-synthesis past the oxidation-damaged base 8-oxoDG. Nature, 1991;349:431-434
-
(1991)
Nature
, vol.349
, pp. 431-434
-
-
Shibutani, S.1
Takeshita, M.2
Grollaman, A.P.3
-
45
-
-
38149051473
-
Clinical evidence for utilization of the A3 adenosine receptor as a target to treat rheumatoid arthritis: Data from a phase II clinical trial
-
Silverman M. H., Strand V., Markovits D., Nahir M., Reitblat T., Molad Y., Rosner I., Rozenbaum M., Mader R., Adawi M., Caspi D., Tishler M., Langevitz P., Rubinow A., Friedman J. i wsp.: Clinical evidence for utilization of the A3 adenosine receptor as a target to treat rheumatoid arthritis: data from a phase II clinical trial. J. Rheumatol., 2008;35:41-48
-
(2008)
J. Rheumatol.
, vol.35
, pp. 41-48
-
-
Silverman, M.H.1
Strand, V.2
Markovits, D.3
Nahir, M.4
Reitblat, T.5
Molad, Y.6
Rosner, I.7
Rozenbaum, M.8
Mader, R.9
Adawi, M.10
Caspi, D.11
Tishler, M.12
Langevitz, P.13
Rubinow, A.14
Friedman, J.15
-
46
-
-
33646457538
-
Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'- fluoro-2'-C-methylcytidine: A specific inhibitor of hepatitis C virus replication
-
Stuyver L., McBrayer T., Tharnish P., Clark J., Hollecker L., Lostia S., Nachman T., Grier J., Bennett M., Xie M., Schinazi R. F., Morrey J. D., Julander J. L., Furman P. A., Otto M. J.: Inhibition of hepatitis C replicon RNA synthesis by beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine: a specific inhibitor of hepatitis C virus replication. Antivir. Chem. Chemother., 2006;17:79-87
-
(2006)
Antivir. Chem. Chemother.
, vol.17
, pp. 79-87
-
-
Stuyver, L.1
McBrayer, T.2
Tharnish, P.3
Clark, J.4
Hollecker, L.5
Lostia, S.6
Nachman, T.7
Grier, J.8
Bennett, M.9
Xie, M.10
Schinazi, R.F.11
Morrey, J.D.12
Julander, J.L.13
Furman, P.A.14
Otto, M.J.15
-
47
-
-
79953764331
-
Receptor desensitization and blockade of the suppressive effects of prostaglandin E (2) and adenosine on the cytotoxic activity of human melanoma-infiltrating T lymphocytes
-
Su Y. Y., Jackson E. K., Gorelik E.: Receptor desensitization and blockade of the suppressive effects of prostaglandin E (2) and adenosine on the cytotoxic activity of human melanoma-infiltrating T lymphocytes. Cancer Immunol. Immunother., 2011;60:111-122
-
(2011)
Cancer Immunol. Immunother.
, vol.60
, pp. 111-122
-
-
Su, Y.Y.1
Jackson, E.K.2
Gorelik, E.3
-
48
-
-
79955907006
-
Adenosine-1, 3-diazaphenoxazine derivative for selective base pair formation with 8-oxo-2'-deoxyguanosine in DNA
-
Taniguchi Y., Kawaguchi R., Sasaki S.: Adenosine-1, 3-diazaphenoxazine derivative for selective base pair formation with 8-oxo-2'-deoxyguanosine in DNA. J. Am. Chem. Soc., 2011;133:7272-7275
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 7272-7275
-
-
Taniguchi, Y.1
Kawaguchi, R.2
Sasaki, S.3
-
49
-
-
79953167994
-
Normal and abnormal functions of adenosine receptors in the central nervous system revealed by genetic knockout studies
-
Wei C. J., Li W., Chen J. F.: Normal and abnormal functions of adenosine receptors in the central nervous system revealed by genetic knockout studies. Biochim. Biophys. Acta, 2011;1808:1358-1379
-
(2011)
Biochim. Biophys. Acta
, vol.1808
, pp. 1358-1379
-
-
Wei, C.J.1
Li, W.2
Chen, J.F.3
-
50
-
-
17044399698
-
ADP-ribosyl cyclase couples to cyclic AMP signaling in the cardiomyocytes
-
Xie G. H., Rah S. Y., Kim S. J., Nam T. S., Ha K. C., Chae S. W., Im M. J., Kim U. H.: ADP-ribosyl cyclase couples to cyclic AMP signaling in the cardiomyocytes. Biochem. Biophys. Res. Commun., 2005;330:1290-1298
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.330
, pp. 1290-1298
-
-
Xie, G.H.1
Rah, S.Y.2
Kim, S.J.3
Nam, T.S.4
Ha, K.C.5
Chae, S.W.6
Im, M.J.7
Kim, U.H.8
-
51
-
-
34250198261
-
Facile quantification of lesions derived from 2'-deoxyguanosine in DNA
-
Xue L., Greenberg M. M.: Facile quantification of lesions derived from 2'-deoxyguanosine in DNA. J. Am. Chem. Soc., 2007;129:7010-7011
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 7010-7011
-
-
Xue, L.1
Greenberg, M.M.2
-
52
-
-
33745727138
-
Synthesis of 2-C-hydroxymethylribofuranosylpurines as potent anti-hepatitis C virus (HCV) agents
-
Yoo B. N., Kim H. O., Moon H. R., Seol S. K., Jang S. K., Lee K. M., Jeong L. S.: Synthesis of 2-C-hydroxymethylribofuranosylpurines as potent anti-hepatitis C virus (HCV) agents. Bioorg. Med. Chem. Lett., 2006;16:4190-4194
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 4190-4194
-
-
Yoo, B.N.1
Kim, H.O.2
Moon, H.R.3
Seol, S.K.4
Jang, S.K.5
Lee, K.M.6
Jeong, L.S.7
-
53
-
-
79957619755
-
Synthesis of a novel benzoyl adenosine analog containing a 1, 4-dioxane sugar analog and the synthesis of a corresponding uracil adenine dinucleotide
-
Yu Q., Carlsen P.: Synthesis of a novel benzoyl adenosine analog containing a 1, 4-dioxane sugar analog and the synthesis of a corresponding uracil adenine dinucleotide. Molecules, 2011;16:3985-3998
-
(2011)
Molecules
, vol.16
, pp. 3985-3998
-
-
Yu, Q.1
Carlsen, P.2
-
54
-
-
78650674078
-
Safety and pharmacokinetics of IDX184, a liver-targeted nucleotide polymerase inhibitor of hepatitis C virus, in healthy subjects
-
Zhou X. J., Pietropaolo K., Chen J., Khan S., Sullivan-Bolyai J., Mayers D.: Safety and pharmacokinetics of IDX184, a liver-targeted nucleotide polymerase inhibitor of hepatitis C virus, in healthy subjects. Antimicrob. Agents Chemother., 2011;55:76-81
-
(2011)
Antimicrob. Agents Chemother.
, vol.55
, pp. 76-81
-
-
Zhou, X.J.1
Pietropaolo, K.2
Chen, J.3
Khan, S.4
Sullivan-Bolyai, J.5
Mayers, D.6
-
55
-
-
33644985973
-
N-6-Ethyl-2-alkynyl NECAs, selective human A (3) adenosine receptor agonists
-
Zhu R., Frazier C. R., Linden J., Macdonald T. L.: N-6-Ethyl-2-alkynyl NECAs, selective human A (3) adenosine receptor agonists. Bioorg. Med. Chem. Lett., 2006;16:2416-2418
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 2416-2418
-
-
Zhu, R.1
Frazier, C.R.2
Linden, J.3
Macdonald, T.L.4
|