Synthesis of 3'-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents

Archives of Pharmacal Research

Volumn 31, Issue 7, 2008, Pages 843-849

  Pei, Xiaojuan ^a,b   Choi, Won Jun ^a   Kim, Yu Min ^a   Zhao, Long Xuan ^a,b   Jeong, Lak Shin ^a  

^a Ewha Womans University   (South Korea)

^b LIAONING NORMAL UNIVERSITY   (China)

Author keywords

3' C hydroxymethyl nucleosides; Anti hepatitis C virus (HCV) activity; Neighboring group effect; Stereoselective Grignard reaction

Indexed keywords

ANTIVIRUS AGENT; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; PURINE NUCLEOSIDE; PYRIMIDINE NUCLEOSIDE;

ARTICLE; CHEMICAL STRUCTURE; CONFORMATION; DRUG DESIGN; DRUG EFFECT; HEPATITIS C VIRUS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS;

ANTIVIRAL AGENTS; DRUG DESIGN; HEPACIVIRUS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PURINE NUCLEOSIDES; PYRIMIDINE NUCLEOSIDES;

EID: 49749093968     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-001-1236-z     Document Type: Article

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