메뉴 건너뛰기




Volumn 8, Issue 11, 2013, Pages

The extreme variety of genotoxic response to benzo[a]pyrene in three different human cell lines from three different organs

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE;

EID: 84892528833     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078356     Document Type: Article
Times cited : (66)

References (67)
  • 1
    • 41949138917 scopus 로고    scopus 로고
    • Atmospheric polycyclic aromatic hydrocarbons: Source attribution, emission factors and regulation
    • Ravindra K, Sokhi R, Van Grieken R (2008) Atmospheric polycyclic aromatic hydrocarbons: Source attribution, emission factors and regulation. Atmos Environ 42: 2895-2921.
    • (2008) Atmos Environ , vol.42 , pp. 2895-2921
    • Ravindra, K.1    Sokhi, R.2    Van Grieken, R.3
  • 2
    • 82655186734 scopus 로고    scopus 로고
    • PAH diagnostic ratios for the identification of pollution emission sources
    • Tobiszewski M, Namieśnik J (2012) PAH diagnostic ratios for the identification of pollution emission sources. Environment Pollut 162: 110-119.
    • (2012) Environment Pollut , vol.162 , pp. 110-119
    • Tobiszewski, M.1    Namieśnik, J.2
  • 3
    • 0030465240 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons and cancer in man
    • Mastrangelo G, Fadda E, Marzia V (1996) Polycyclic aromatic hydrocarbons and cancer in man. Environ Heath Perspect 104: 1166-1170.
    • (1996) Environ Heath Perspect , vol.104 , pp. 1166-1170
    • Mastrangelo, G.1    Fadda, E.2    Marzia, V.3
  • 4
    • 0030045118 scopus 로고    scopus 로고
    • The use of toxic equivalency factors in assessing occupational and environmental health risk associated with exposure to airborne mixtures of polycyclic aromatic hydrocarbons (PAHs)
    • Petry T, Schmid P, Schlatter C (1996) The use of toxic equivalency factors in assessing occupational and environmental health risk associated with exposure to airborne mixtures of polycyclic aromatic hydrocarbons (PAHs). Chemosphere 32: 639-648.
    • (1996) Chemosphere , vol.32 , pp. 639-648
    • Petry, T.1    Schmid, P.2    Schlatter, C.3
  • 5
    • 0028364672 scopus 로고
    • Replacement of animal procedures: Alternatives in research, education and testing
    • Balls M (1994) Replacement of animal procedures: alternatives in research, education and testing. Lab Anim 28: 193-211.
    • (1994) Lab Anim , vol.28 , pp. 193-211
    • Balls, M.1
  • 6
    • 33847625536 scopus 로고    scopus 로고
    • Occupational exposures to polycyclic aromatic hydrocarbons, and respiratory and urinary tract cancers: A quantitative review to 2005
    • Bosetti C, Boffetta P, La Vecchia C (2007) Occupational exposures to polycyclic aromatic hydrocarbons, and respiratory and urinary tract cancers: a quantitative review to 2005. Ann Oncol 18: 431-446.
    • (2007) Ann Oncol , vol.18 , pp. 431-446
    • Bosetti, C.1    Boffetta, P.2    La Vecchia, C.3
  • 7
    • 84867884450 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse
    • Siddens LK, Larkin A, Krueger SK, Bradfield CA, Waters KM, et al. (2012) Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse. Toxicol Appl Pharmacol 264: 377-386.
    • (2012) Toxicol Appl Pharmacol , vol.264 , pp. 377-386
    • Siddens, L.K.1    Larkin, A.2    Krueger, S.K.3    Bradfield, C.A.4    Waters, K.M.5
  • 8
    • 34547590367 scopus 로고    scopus 로고
    • Bladder cancer incidence and exposure to polycyclic aromatic hydrocarbons among asphalt pavers
    • Burstyn I, Kromhout H, Johansen C, Langard S, Kauppinen T, et al. (2007) Bladder cancer incidence and exposure to polycyclic aromatic hydrocarbons among asphalt pavers. Occup Environ Med 64: 520-526.
    • (2007) Occup Environ Med , vol.64 , pp. 520-526
    • Burstyn, I.1    Kromhout, H.2    Johansen, C.3    Langard, S.4    Kauppinen, T.5
  • 10
    • 20444412643 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: A review
    • Xue W, Warshawsky D (2005) Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: A review. Toxicol Appl Pharmacol 206: 73-93.
    • (2005) Toxicol Appl Pharmacol , vol.206 , pp. 73-93
    • Xue, W.1    Warshawsky, D.2
  • 11
    • 0028897519 scopus 로고
    • Polycyclic aromatic hydrocarbons: Chemistry of DNA adduct formation
    • Peltonen K, Dipple A (1995) Polycyclic aromatic hydrocarbons: chemistry of DNA adduct formation. J Occup Environ Med 37: 52-58.
    • (1995) J Occup Environ Med , vol.37 , pp. 52-58
    • Peltonen, K.1    Dipple, A.2
  • 12
    • 34047243800 scopus 로고    scopus 로고
    • Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons
    • Shimada T (2006) Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons. Drug Metab Pharmacokinet 21: 257-276.
    • (2006) Drug Metab Pharmacokinet , vol.21 , pp. 257-276
    • Shimada, T.1
  • 13
    • 5044245540 scopus 로고    scopus 로고
    • In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism
    • Briede JJ, Godschalk RW, Emans MT, De Kok TM, Van Agen E, et al. (2004) In vitro and in vivo studies on oxygen free radical and DNA adduct formation in rat lung and liver during benzo[a]pyrene metabolism. Free Radic Res 38: 995-1002.
    • (2004) Free Radic Res , vol.38 , pp. 995-1002
    • Briede, J.J.1    Godschalk, R.W.2    Emans, M.T.3    De Kok, T.M.4    Van Agen, E.5
  • 14
    • 34248659644 scopus 로고    scopus 로고
    • The relationship between biomarkers of oxidative DNA damage, polycyclic aromatic hydrocarbon DNA adducts, antioxidant status and genetic susceptibility following exposure to environmental air pollution in humans
    • Singh R, Sram RJ, Binkova B, Kalina I, Popov TA, et al. (2007) The relationship between biomarkers of oxidative DNA damage, polycyclic aromatic hydrocarbon DNA adducts, antioxidant status and genetic susceptibility following exposure to environmental air pollution in humans. Mutat Res 620: 83-92.
    • (2007) Mutat Res , vol.620 , pp. 83-92
    • Singh, R.1    Sram, R.J.2    Binkova, B.3    Kalina, I.4    Popov, T.A.5
  • 15
    • 79952694454 scopus 로고    scopus 로고
    • An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway
    • Tsuji G, Takahara M, Uchi H, Takeuchi S, Mitoma C, et al. (2011) An environmental contaminant, benzo(a)pyrene, induces oxidative stress-mediated interleukin-8 production in human keratinocytes via the aryl hydrocarbon receptor signaling pathway. J Dermatol Sci 62: 42-49.
    • (2011) J Dermatol Sci , vol.62 , pp. 42-49
    • Tsuji, G.1    Takahara, M.2    Uchi, H.3    Takeuchi, S.4    Mitoma, C.5
  • 16
    • 70350536343 scopus 로고    scopus 로고
    • Relative contribution of DNA strand breaks and DNA adducts to the genotoxicity of benzo[a]pyrene as a pure compound and in complex mixtures
    • Tarantini A, Maitre A, Lefebvre E, Marques M, Marie C, et al. (2009) Relative contribution of DNA strand breaks and DNA adducts to the genotoxicity of benzo[a]pyrene as a pure compound and in complex mixtures. Mutat Res 671: 67-75.
    • (2009) Mutat Res , vol.671 , pp. 67-75
    • Tarantini, A.1    Maitre, A.2    Lefebvre, E.3    Marques, M.4    Marie, C.5
  • 17
    • 38549143798 scopus 로고    scopus 로고
    • Changes in gene expression induced by polycyclic aromatic hydrocarbons in the human cell lines HepG2 and A549
    • Castorena-Torres F, de León MB, Cisneros B, Zapata-Pérez O, Salinas JE, et al. (2008) Changes in gene expression induced by polycyclic aromatic hydrocarbons in the human cell lines HepG2 and A549. Toxicol in vitro 22: 411-421.
    • (2008) Toxicol in Vitro , vol.22 , pp. 411-421
    • Castorena-Torres, F.1    De León, M.B.2    Cisneros, B.3    Zapata-Pérez, O.4    Salinas, J.E.5
  • 18
    • 34248637585 scopus 로고    scopus 로고
    • In vitro genotoxicity of PAH mixtures and organic extract from urban air particles: Part II: Human cell lines
    • Sevastyanova O, Binkova B, Topinka J, Sram RJ, Kalina I, et al. (2007) In vitro genotoxicity of PAH mixtures and organic extract from urban air particles: Part II: Human cell lines. Mutat Res 620: 123-134.
    • (2007) Mutat Res , vol.620 , pp. 123-134
    • Sevastyanova, O.1    Binkova, B.2    Topinka, J.3    Sram, R.J.4    Kalina, I.5
  • 19
    • 47549119258 scopus 로고    scopus 로고
    • Influence of the metabolic properties of human cells on the kinetic of formation of the major benzo[a]pyrene DNA adducts
    • Marie C, Maître A, Douki T, Gateau M, Tarantini A, et al. (2008) Influence of the metabolic properties of human cells on the kinetic of formation of the major benzo[a]pyrene DNA adducts. J Appl Toxicol 28: 579-590.
    • (2008) J Appl Toxicol , vol.28 , pp. 579-590
    • Marie, C.1    Maître, A.2    Douki, T.3    Gateau, M.4    Tarantini, A.5
  • 20
    • 0000695308 scopus 로고
    • Measurement of strand breaks by alkaline denaturation and hydroxyapatite chromatography
    • Friedberg EC, Hanawalt PC, editors. New-York: Marcel Dekker
    • Ahnström G, Erixon K (1981) Measurement of strand breaks by alkaline denaturation and hydroxyapatite chromatography. In: Friedberg EC, Hanawalt PC, editors. DNA repair: A Laboratory Manuel Research Procedures. New-York: Marcel Dekker. 403-418.
    • (1981) DNA Repair: A Laboratory Manuel Research Procedures , pp. 403-418
    • Ahnström, G.1    Erixon, K.2
  • 21
    • 0024345179 scopus 로고
    • The initial physical damage produced by ionizing radiations
    • Goodhead DT (1989) The initial physical damage produced by ionizing radiations. Int J Radiat Biol 56: 623-634.
    • (1989) Int J Radiat Biol , vol.56 , pp. 623-634
    • Goodhead, D.T.1
  • 22
    • 0033914527 scopus 로고    scopus 로고
    • DNA damage induced in cells by gamma and UVA radiations as measured by HPLC/GC-MS, HPLC-EC and comet assay
    • Pouget J-P, Douki T, Richard M-J, Cadet J (2000) DNA damage induced in cells by gamma and UVA radiations as measured by HPLC/GC-MS, HPLC-EC and comet assay. Chem Res Toxicol 13: 541-549.
    • (2000) Chem Res Toxicol , vol.13 , pp. 541-549
    • Pouget, J.-P.1    Douki, T.2    Richard, M.-J.3    Cadet, J.4
  • 23
    • 84870702756 scopus 로고    scopus 로고
    • Alzheimer's disease-associated neurotoxic Peptide amyloid-beta impairs base excision repair in human neuroblastoma cells
    • Forestier A, Douki T, Sauvaigo S, Rosa VD, Demeilliers C, et al. (2012) Alzheimer's disease-associated neurotoxic Peptide amyloid-beta impairs base excision repair in human neuroblastoma cells. Int J Mol Sci 13: 14766-14787.
    • (2012) Int J Mol Sci , vol.13 , pp. 14766-14787
    • Forestier, A.1    Douki, T.2    Sauvaigo, S.3    Rosa, V.D.4    Demeilliers, C.5
  • 24
    • 0016275313 scopus 로고
    • Glutathione S-Transferases: The first enzymatic step in mercapturic acid formation
    • Habig WH, Pabst MJ, Jakoby WB (1974) Glutathione S-Transferases: The first enzymatic step in mercapturic acid formation. J Biol Chem 249: 7130-7139.
    • (1974) J Biol Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 25
    • 0027485560 scopus 로고
    • A Fluorescence-Based Protein Assay for Use with a Microplate Reader
    • Lorenzen A, Kennedy SW (1993) A Fluorescence-Based Protein Assay for Use with a Microplate Reader. Anal Biochem 214: 346-348.
    • (1993) Anal Biochem , vol.214 , pp. 346-348
    • Lorenzen, A.1    Kennedy, S.W.2
  • 26
    • 51049119228 scopus 로고    scopus 로고
    • Genotoxic potential of Polycyclic Aromatic Hydrocarbons-coated onto airborne Particulate Matter (PM 2.5) in human lung epithelial A549 cells
    • Billet S, Abbas I, Le Goff J, Verdin A, Andre V, et al. (2008) Genotoxic potential of Polycyclic Aromatic Hydrocarbons-coated onto airborne Particulate Matter (PM 2.5) in human lung epithelial A549 cells. Cancer Lett 270: 144-155.
    • (2008) Cancer Lett , vol.270 , pp. 144-155
    • Billet, S.1    Abbas, I.2    Le Goff, J.3    Verdin, A.4    Andre, V.5
  • 27
    • 36148955117 scopus 로고    scopus 로고
    • Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells
    • Westerink WM, Schoonen WG (2007) Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells. Toxicol In Vitro 21: 1581-1591.
    • (2007) Toxicol in Vitro , vol.21 , pp. 1581-1591
    • Westerink, W.M.1    Schoonen, W.G.2
  • 28
    • 0042065286 scopus 로고    scopus 로고
    • Influence of culture time on the expression of drugmetabolizing enzymes in primary human hepatocytes and hepatoma cell line HepG2
    • Wilkening S, Bader A (2003) Influence of culture time on the expression of drugmetabolizing enzymes in primary human hepatocytes and hepatoma cell line HepG2. J Biochem Mol Toxicol 17: 207-213.
    • (2003) J Biochem Mol Toxicol , vol.17 , pp. 207-213
    • Wilkening, S.1    Bader, A.2
  • 29
    • 0042904900 scopus 로고    scopus 로고
    • Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties
    • Wilkening S, Stahl F, Bader A (2003) Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties. Drug Metab Dispos 31: 1035-1042.
    • (2003) Drug Metab Dispos , vol.31 , pp. 1035-1042
    • Wilkening, S.1    Stahl, F.2    Bader, A.3
  • 30
    • 0037439497 scopus 로고    scopus 로고
    • Quantitation of CYP1A1 and 1B1 mRNA in polycyclic aromatic hydrocarbon-treated human T-47D and HepG2 cells by a modified bDNA assay using fluorescence detection
    • Wu SJ, Spink DC, Spink BC, Kaminsky LS (2003) Quantitation of CYP1A1 and 1B1 mRNA in polycyclic aromatic hydrocarbon-treated human T-47D and HepG2 cells by a modified bDNA assay using fluorescence detection. Anal Biochem 312: 162-166.
    • (2003) Anal Biochem , vol.312 , pp. 162-166
    • Wu, S.J.1    Spink, D.C.2    Spink, B.C.3    Kaminsky, L.S.4
  • 31
    • 0035699984 scopus 로고    scopus 로고
    • Dosedependent differences in the profile of mutations induced by carcinogenic (R,S,S,R) bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons
    • Conney AH, Chang RL, Cui XX, Schiltz M, Yagi H, et al. (2001) Dosedependent differences in the profile of mutations induced by carcinogenic (R,S,S,R) bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons. Adv Exp Med Biol 500: 697-707.
    • (2001) Adv Exp Med Biol , vol.500 , pp. 697-707
    • Conney, A.H.1    Chang, R.L.2    Cui, X.X.3    Schiltz, M.4    Yagi, H.5
  • 32
    • 0033385163 scopus 로고    scopus 로고
    • Characterization of the mutational profile of (+)-7R,8S-dihydroxy-9S, 10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene at the hypoxanthine (guanine) phosphoribosyltransferase gene in repair-deficient Chinese hamster V-H1 cells
    • Schiltz M, Cui XX, Lu YP, Yagi H, Jerina DM, et al. (1999) Characterization of the mutational profile of (+)-7R,8S-dihydroxy-9S, 10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene at the hypoxanthine (guanine) phosphoribosyltransferase gene in repair-deficient Chinese hamster V-H1 cells. Carcinogenesis 20: 2279-2286.
    • (1999) Carcinogenesis , vol.20 , pp. 2279-2286
    • Schiltz, M.1    Cui, X.X.2    Lu, Y.P.3    Yagi, H.4    Jerina, D.M.5
  • 33
    • 84855831273 scopus 로고    scopus 로고
    • Aldo-keto reductases protect lung adenocarcinoma cells from the acute toxicity of B[a]P-7,8-trans-dihydrodiol
    • Abedin Z, Sen S, Field J (2012) Aldo-keto reductases protect lung adenocarcinoma cells from the acute toxicity of B[a]P-7,8-trans-dihydrodiol. Chem Res Toxicol 25: 113-121.
    • (2012) Chem Res Toxicol , vol.25 , pp. 113-121
    • Abedin, Z.1    Sen, S.2    Field, J.3
  • 34
    • 71749120759 scopus 로고    scopus 로고
    • DNA damage in A549 cells exposed to different extracts of PM(2.5) from industrial, urban and highway sites
    • Bonetta S, Gianotti V, Gosetti F, Oddone M, Gennaro MC, et al. (2009) DNA damage in A549 cells exposed to different extracts of PM(2.5) from industrial, urban and highway sites. Chemosphere 77: 1030-1034.
    • (2009) Chemosphere , vol.77 , pp. 1030-1034
    • Bonetta, S.1    Gianotti, V.2    Gosetti, F.3    Oddone, M.4    Gennaro, M.C.5
  • 35
    • 79951822391 scopus 로고    scopus 로고
    • Oxidative stress, DNA damage, and inflammation induced by ambient air and wood smoke particulate matter in human A549 and THP-1 cell lines
    • Danielsen PH, Moller P, Jensen KA, Sharma AK, Wallin H, et al. (2011) Oxidative stress, DNA damage, and inflammation induced by ambient air and wood smoke particulate matter in human A549 and THP-1 cell lines. Chem Res Toxicol 24: 168-184.
    • (2011) Chem Res Toxicol , vol.24 , pp. 168-184
    • Danielsen, P.H.1    Moller, P.2    Jensen, K.A.3    Sharma, A.K.4    Wallin, H.5
  • 36
    • 1542376626 scopus 로고    scopus 로고
    • The genotoxic effect of carcinogenic PAHs, their artificial and environmental mixtures (EOM) on human diploid lung fibroblasts
    • Binkova B, Sram RJ (2004) The genotoxic effect of carcinogenic PAHs, their artificial and environmental mixtures (EOM) on human diploid lung fibroblasts. Mutat Res 547: 109-121.
    • (2004) Mutat Res , vol.547 , pp. 109-121
    • Binkova, B.1    Sram, R.J.2
  • 37
    • 0032402090 scopus 로고    scopus 로고
    • Human-derived cell lines to study xenobiotic metabolism
    • Urani C, Doldi M, Crippa S, Camatini M (1998) Human-derived cell lines to study xenobiotic metabolism. Chemosphere 37: 2785-2795.
    • (1998) Chemosphere , vol.37 , pp. 2785-2795
    • Urani, C.1    Doldi, M.2    Crippa, S.3    Camatini, M.4
  • 38
    • 37249077516 scopus 로고    scopus 로고
    • Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size
    • Pushparajah DS, Umachandran M, Nazir T, Plant KE, Plant N, et al. (2008) Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size. Toxicol in vitro 22: 128-145.
    • (2008) Toxicol in Vitro , vol.22 , pp. 128-145
    • Pushparajah, D.S.1    Umachandran, M.2    Nazir, T.3    Plant, K.E.4    Plant, N.5
  • 39
    • 17044423833 scopus 로고    scopus 로고
    • Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action
    • Baird WM, Hooven LA, Mahadevan B (2005) Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action. Environ Mol Mutagen 45: 106-114.
    • (2005) Environ Mol Mutagen , vol.45 , pp. 106-114
    • Baird, W.M.1    Hooven, L.A.2    Mahadevan, B.3
  • 40
    • 78651471875 scopus 로고    scopus 로고
    • Regulation of benzo[a]pyrene-mediated DNA-and glutathione-adduct formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in human lung cells
    • Gelhaus SL, Harvey RG, Penning TM, Blair IA (2011) Regulation of benzo[a]pyrene-mediated DNA-and glutathione-adduct formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in human lung cells. Chem Res Toxicol 24: 89-98.
    • (2011) Chem Res Toxicol , vol.24 , pp. 89-98
    • Gelhaus, S.L.1    Harvey, R.G.2    Penning, T.M.3    Blair, I.A.4
  • 41
    • 84907034868 scopus 로고
    • The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part II
    • Hayes JD, Pulford DJ (1995) The Glut athione S-Transferase Supergene Family: Regulation of GST and the Contribution of the lsoenzymes to Cancer Chemoprotection and Drug Resistance Part II. Critical Rev Biochem Molec Biol 30: 521-600.
    • (1995) Critical Rev Biochem Molec Biol , vol.30 , pp. 521-600
    • Hayes, J.D.1    Pulford, D.J.2
  • 42
    • 0038730945 scopus 로고    scopus 로고
    • Quantitative analysis of the Ah receptor/cytochrome P450 CYP1B1/CYP1A1 signalling pathway
    • McFadyen MCE, Rooney PH, Melvin WT, Murray GI (2003) Quantitative analysis of the Ah receptor/cytochrome P450 CYP1B1/CYP1A1 signalling pathway. Biochem Pharmacol 65: 1663-1674.
    • (2003) Biochem Pharmacol , vol.65 , pp. 1663-1674
    • McFadyen, M.C.E.1    Rooney, P.H.2    Melvin, W.T.3    Murray, G.I.4
  • 43
    • 1142275258 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1
    • Shimada T, Fujii-Kuriyama Y (2004) Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1. Cancer Sci 95: 1-6.
    • (2004) Cancer Sci , vol.95 , pp. 1-6
    • Shimada, T.1    Fujii-Kuriyama, Y.2
  • 44
    • 0036016866 scopus 로고    scopus 로고
    • Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: Chemical-, cytochrome P450 isoform-, and cell-specific differences
    • Iwanari M, Nakajima M, Kizu R, Hayakawa K, Yokoi T (2002) Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences. Arch Toxicol 76: 287-298.
    • (2002) Arch Toxicol , vol.76 , pp. 287-298
    • Iwanari, M.1    Nakajima, M.2    Kizu, R.3    Hayakawa, K.4    Yokoi, T.5
  • 45
    • 33645240574 scopus 로고    scopus 로고
    • Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene
    • Harrigan JA, McGarrigle BP, Sutter TR, Olson JR (2006) Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene. Toxicol In Vitro 20: 426-438.
    • (2006) Toxicol in Vitro , vol.20 , pp. 426-438
    • Harrigan, J.A.1    McGarrigle, B.P.2    Sutter, T.R.3    Olson, J.R.4
  • 46
    • 1342310142 scopus 로고    scopus 로고
    • DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene
    • Harrigan JA, Vezina CM, McGarrigle BP, Ersing N, Box HC, et al. (2004) DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene. Toxicol Sci 77: 307-314.
    • (2004) Toxicol Sci , vol.77 , pp. 307-314
    • Harrigan, J.A.1    Vezina, C.M.2    McGarrigle, B.P.3    Ersing, N.4    Box, H.C.5
  • 47
    • 0034876318 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella Typhimurium NM2009
    • Shimada T, Oda Y, Gillam EMJ, Guengerich FP, Inoue K (2001) Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella Typhimurium NM2009. Drug Metab Dispos 29: 1176-1182.
    • (2001) Drug Metab Dispos , vol.29 , pp. 1176-1182
    • Shimada, T.1    Oda, Y.2    Gillam, E.M.J.3    Guengerich, F.P.4    Inoue, K.5
  • 48
    • 0034671583 scopus 로고    scopus 로고
    • The human cytochrome P450 1A1 mRNA is rapidly degraded in HepG2 cells
    • Lekas P, Tin KL, Lee C, Prokipcak RD (2000) The human cytochrome P450 1A1 mRNA is rapidly degraded in HepG2 cells. Arch Biochem Biophys 384: 311-318.
    • (2000) Arch Biochem Biophys , vol.384 , pp. 311-318
    • Lekas, P.1    Tin, K.L.2    Lee, C.3    Prokipcak, R.D.4
  • 49
    • 0029956983 scopus 로고    scopus 로고
    • Glutathione Stransferase A1-1-catalysed conjugation of bay and fjord region diol epoxides or polycyclic aromatic hydrocarbons with glutathione
    • Jernstrom B, Funk M, Frank H, Mannervik B, Seidel A (1996) Glutathione Stransferase A1-1-catalysed conjugation of bay and fjord region diol epoxides or polycyclic aromatic hydrocarbons with glutathione. Carcinogenesis 17: 1491-1498.
    • (1996) Carcinogenesis , vol.17 , pp. 1491-1498
    • Jernstrom, B.1    Funk, M.2    Frank, H.3    Mannervik, B.4    Seidel, A.5
  • 50
    • 0036174215 scopus 로고    scopus 로고
    • Glutathione conjugation and DNA adduct formation of dibenzo[a,l]pyrene and benzo[a]pyrene diol epoxides in V79 cells stably expressing different human glutathione transferases
    • Sundberg K, Dreij K, Seidel A, Jernstrom B (2002) Glutathione conjugation and DNA adduct formation of dibenzo[a,l]pyrene and benzo[a]pyrene diol epoxides in V79 cells stably expressing different human glutathione transferases. Chem Res Toxicol 15: 170-179.
    • (2002) Chem Res Toxicol , vol.15 , pp. 170-179
    • Sundberg, K.1    Dreij, K.2    Seidel, A.3    Jernstrom, B.4
  • 51
    • 0035998281 scopus 로고    scopus 로고
    • Catalytic activities of human alpha class glutathione transferases toward carcinogenic dibenzo[a,l]pyrene diol epoxides
    • Dreij K, Sundberg K, Johansson AS, Nordling E, Seidel A, et al. (2002) Catalytic activities of human alpha class glutathione transferases toward carcinogenic dibenzo[a,l]pyrene diol epoxides. Chem Res Toxicol 15: 825-831.
    • (2002) Chem Res Toxicol , vol.15 , pp. 825-831
    • Dreij, K.1    Sundberg, K.2    Johansson, A.S.3    Nordling, E.4    Seidel, A.5
  • 52
    • 0031767266 scopus 로고    scopus 로고
    • Detoxication of carcinogenic fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferase P1-1 variants and glutathione
    • Sundberg K, Seidel A, Mannervik B, Jernstrom B (1998) Detoxication of carcinogenic fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferase P1-1 variants and glutathione. FEBS Lett 438: 206-210.
    • (1998) FEBS Lett , vol.438 , pp. 206-210
    • Sundberg, K.1    Seidel, A.2    Mannervik, B.3    Jernstrom, B.4
  • 53
    • 46349100716 scopus 로고    scopus 로고
    • Upregulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung
    • Pushparajah DS, Umachandran M, Plant KE, Plant N, Ioannides C (2008) Upregulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung. Mutagenesis 23: 299-308.
    • (2008) Mutagenesis , vol.23 , pp. 299-308
    • Pushparajah, D.S.1    Umachandran, M.2    Plant, K.E.3    Plant, N.4    Ioannides, C.5
  • 54
    • 0037025386 scopus 로고    scopus 로고
    • Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells
    • Palackal NT, Lee SH, Harvey RG, Blair IA, Penning TM (2002) Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells. J Biol Chem 277: 24799-24808.
    • (2002) J Biol Chem , vol.277 , pp. 24799-24808
    • Palackal, N.T.1    Lee, S.H.2    Harvey, R.G.3    Blair, I.A.4    Penning, T.M.5
  • 55
    • 47549097394 scopus 로고    scopus 로고
    • Comparisons of (±α)-benzo[a]pyrene-trans-7,8-dihydrodiol activation by human cytochrome P450 and aldo-keto reductase enzymes: Effect of redox state and expression levels
    • Quinn AM, Penning TM (2008) Comparisons of (±α)-benzo[a] pyrene-trans-7,8-dihydrodiol activation by human cytochrome P450 and aldo-keto reductase enzymes: Effect of redox state and expression levels. Chem Res Toxicol 21: 1086-1094.
    • (2008) Chem Res Toxicol , vol.21 , pp. 1086-1094
    • Quinn, A.M.1    Penning, T.M.2
  • 56
    • 0028918121 scopus 로고
    • Estimation of risk of developing bladder cancer among workers exposed to coal tar pitch volatiles in the primary aluminum industry
    • Tremblay C, Armstrong B, Theriault G, Brodeur J (1995) Estimation of risk of developing bladder cancer among workers exposed to coal tar pitch volatiles in the primary aluminum industry. Am J Indiv Med 27: 335-348.
    • (1995) Am J Indiv Med , vol.27 , pp. 335-348
    • Tremblay, C.1    Armstrong, B.2    Theriault, G.3    Brodeur, J.4
  • 57
    • 0033794510 scopus 로고    scopus 로고
    • Cytochrome P450 isoenzyme mRNA expression pattern in human urinary bladder malignancies and normal urothelium
    • Brauers A, Manegold E, Buettner R, Baron JM, Merk HF, et al. (2000) Cytochrome P450 isoenzyme mRNA expression pattern in human urinary bladder malignancies and normal urothelium. Cancer Detec Prev 24: 356-363.
    • (2000) Cancer Detec Prev , vol.24 , pp. 356-363
    • Brauers, A.1    Manegold, E.2    Buettner, R.3    Baron, J.M.4    Merk, H.F.5
  • 58
    • 10444275098 scopus 로고    scopus 로고
    • The effect of benzo(a)pyrene on porcine urinary bladder epithelial cells analyzed for the expression of selected genes and cellular toxicological endpoints
    • Wolf A, Kutz A, Plottner S, Behm C, Bolt HM, et al. (2005) The effect of benzo(a)pyrene on porcine urinary bladder epithelial cells analyzed for the expression of selected genes and cellular toxicological endpoints. Toxicology 207: 255-269.
    • (2005) Toxicology , vol.207 , pp. 255-269
    • Wolf, A.1    Kutz, A.2    Plottner, S.3    Behm, C.4    Bolt, H.M.5
  • 59
    • 84871212796 scopus 로고    scopus 로고
    • Exposure of primary porcine urothelial cells to benzo(a)pyrene: In vitro uptake, intracellular concentration, and biological response
    • Verma N, Pink M, Petrat F, Rettenmeier AW, Schmitz-Spanke S (2012) Exposure of primary porcine urothelial cells to benzo(a)pyrene: in vitro uptake, intracellular concentration, and biological response. Arch Toxicol 86: 1861-1871.
    • (2012) Arch Toxicol , vol.86 , pp. 1861-1871
    • Verma, N.1    Pink, M.2    Petrat, F.3    Rettenmeier, A.W.4    Schmitz-Spanke, S.5
  • 60
    • 47349122451 scopus 로고    scopus 로고
    • Evaluation of time dependence and interindividual differences in benzo[a]pyrene-mediated CYP1A1 induction and genotoxicity in porcine urinary bladder cell cultures
    • Plottner S, Borza A, Wolf A, Bolt HM, Kuhlmann J, et al. (2008) Evaluation of time dependence and interindividual differences in benzo[a]pyrene-mediated CYP1A1 induction and genotoxicity in porcine urinary bladder cell cultures. J Toxicol Environ Health A 71: 969-975.
    • (2008) J Toxicol Environ Health A , vol.71 , pp. 969-975
    • Plottner, S.1    Borza, A.2    Wolf, A.3    Bolt, H.M.4    Kuhlmann, J.5
  • 61
    • 60449106714 scopus 로고    scopus 로고
    • Distinct subtypes of urinary bladder epithelial cells with inducible and non-inducible cytochrome P450 1A1
    • Plottner S, Selinski S, Bolt HM, Degen GH, Hengstler JG, et al. (2009) Distinct subtypes of urinary bladder epithelial cells with inducible and non-inducible cytochrome P450 1A1. Arch Toxicol 83: 131-138.
    • (2009) Arch Toxicol , vol.83 , pp. 131-138
    • Plottner, S.1    Selinski, S.2    Bolt, H.M.3    Degen, G.H.4    Hengstler, J.G.5
  • 62
    • 0020529117 scopus 로고
    • Interspecies comparisons of benzo(a)pyrene metabolism and DNA-adduct formation in cultured human and animal bladder and tracheobronchial tissues
    • Daniel FB, Schut HA, Sandwisch DW, Schenck KM, Hoffmann CO, et al. (1983) Interspecies comparisons of benzo(a)pyrene metabolism and DNA-adduct formation in cultured human and animal bladder and tracheobronchial tissues. Cancer Res 43: 4723-4729.
    • (1983) Cancer Res , vol.43 , pp. 4723-4729
    • Daniel, F.B.1    Schut, H.A.2    Sandwisch, D.W.3    Schenck, K.M.4    Hoffmann, C.O.5
  • 63
    • 0020035873 scopus 로고
    • Metabolism and binding of benzo(a)pyrene and 2-acetylaminofluorene by short-term organ cultures of human and rat bladder
    • Moore BP, Hicks RM, Knowles MA, Redgrave S (1982) Metabolism and binding of benzo(a)pyrene and 2-acetylaminofluorene by short-term organ cultures of human and rat bladder. Cancer Res 42: 642-648.
    • (1982) Cancer Res , vol.42 , pp. 642-648
    • Moore, B.P.1    Hicks, R.M.2    Knowles, M.A.3    Redgrave, S.4
  • 64
    • 70350351227 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2′-deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8-dione
    • Park JH, Mangal D, Frey AJ, Harvey RG, Blair IA, et al. (2009) Aryl hydrocarbon receptor facilitates DNA strand breaks and 8-oxo-2′- deoxyguanosine formation by the aldo-keto reductase product benzo[a]pyrene-7,8- dione. J Biol Chem 284: 29725-29734.
    • (2009) J Biol Chem , vol.284 , pp. 29725-29734
    • Park, J.H.1    Mangal, D.2    Frey, A.J.3    Harvey, R.G.4    Blair, I.A.5
  • 65
    • 67649949088 scopus 로고    scopus 로고
    • Analysis of 7,8-dihydro-8-oxo-2′-deoxyguanosine in cellular DNA during oxidative stress
    • Mangal D, Vudathala D, Park JH, Lee SH, Penning TM, et al. (2009) Analysis of 7,8-dihydro-8-oxo-2′-deoxyguanosine in cellular DNA during oxidative stress. Chem Res Toxicol 22: 788-797.
    • (2009) Chem Res Toxicol , vol.22 , pp. 788-797
    • Mangal, D.1    Vudathala, D.2    Park, J.H.3    Lee, S.H.4    Penning, T.M.5
  • 66
    • 84866022253 scopus 로고    scopus 로고
    • Internal exposure to carcinogenic polycyclic aromatic hydrocarbons and DNA damage: A null result in brief
    • Käfferlein HU, Marczynski B, Simon P, Angerer J, Rihs HP, et al. (2012) Internal exposure to carcinogenic polycyclic aromatic hydrocarbons and DNA damage: a null result in brief. Arch Toxicol 86: 1317-1321.
    • (2012) Arch Toxicol , vol.86 , pp. 1317-1321
    • Käfferlein, H.U.1    Marczynski, B.2    Simon, P.3    Angerer, J.4    Rihs, H.P.5
  • 67
    • 60849098209 scopus 로고    scopus 로고
    • Urinary levels of oxidative DNA and RNA damage among workers exposed to polycyclic aromatic hydrocarbons in silicon production: Comparison with 1-hydroxypyrene
    • Marie C, Ravanat JL, Badouard C, Marques M, Balducci F, et al. (2009) Urinary levels of oxidative DNA and RNA damage among workers exposed to polycyclic aromatic hydrocarbons in silicon production: comparison with 1-hydroxypyrene. Environ Mol Mutagen 50: 88-95.
    • (2009) Environ Mol Mutagen , vol.50 , pp. 88-95
    • Marie, C.1    Ravanat, J.L.2    Badouard, C.3    Marques, M.4    Balducci, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.