Exposure of primary porcine urothelial cells to benzo(a)pyrene: In vitro uptake, intracellular concentration, and biological response

Archives of Toxicology

Volumn 86, Issue 12, 2012, Pages 1861-1871

  Verma, Nisha ^a   Pink, Mario ^a   Petrat, Frank ^a   Rettenmeier, Albert W ^a   Schmitz Spanke, Simone ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Benzo(a)pyrene (BaP); Confocal laser microscopy; Cytosolic medium; Pig; Polycyclic aromatic hydrocarbon; Primary urinary bladder epithelial cells (PUBEC); Quantification; Subcellular distribution; Uptake

Indexed keywords

BENZO[A]PYRENE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLADDER CANCER; BLADDER EPITHELIUM; CALIBRATION; CELL LEVEL; CELL MEMBRANE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CHEMICAL CARCINOGENESIS; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOSOL; EPITHELIUM CELL; FLUORESCENCE ANALYSIS; IN VITRO STUDY; INCUBATION TIME; INTRACELLULAR TRANSPORT; MASS FRAGMENTOGRAPHY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPECTROFLUOROMETRY; SWINE; TRANSITIONAL CELL CARCINOMA;

ANIMALS; BENZO(A)PYRENE; CARCINOGENS; CELL LINE; DNA FRAGMENTATION; EPITHELIAL CELLS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; IN SITU NICK-END LABELING; INDICATORS AND REAGENTS; KINETICS; MICROSCOPY, CONFOCAL; SUBCELLULAR FRACTIONS; SWINE; UROTHELIUM;

SUIDAE; SUS;

EID: 84871212796     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-012-0899-y     Document Type: Article

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