Curcumin inhibits lung cancer cell migration and invasion through Rac1-dependent signaling pathway

Journal of Nutritional Biochemistry

Volumn 25, Issue 2, 2014, Pages 177-185

  Chen, Qing yong ^a   Zheng, Ying ^a,b   Jiao, De min ^a   Chen, Fang yuan ^c   Hu, Hui zhen ^a   Wu, Yu quan ^a   Song, Jia ^a   Yan, Jie ^a   Wu, Li jun ^a   Lv, Gui yuan ^b  

^a The 117th Hospital of Chinese PLA   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^c SHAANXI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Actin cytoskeleton; Curcumin; Invasion; Migration; MMP 2 9; Rac1

Indexed keywords

CURCUMIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE A; GELATINASE B; RAC1 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL ADHESION; CELL INVASION; CELL MIGRATION; CELL MOTILITY; COMPARATIVE STUDY; CONTROLLED STUDY; EPITHELIUM CELL; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; LUNG CANCER; LUNG PARENCHYMA; METASTASIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION INITIATION; TUMOR INVASION;

ACTIN CYTOSKELETON; CURCUMIN; INVASION; MIGRATION; MMP-2/9; RAC1;

CELL LINE, TUMOR; CELL MOVEMENT; CURCUMIN; HUMANS; LUNG NEOPLASMS; NEOPLASM INVASIVENESS; P21-ACTIVATED KINASES; PHOSPHORYLATION; RAC1 GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 84892524801     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2013.10.004     Document Type: Article

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