Curcumin induces apoptosis in human lung adenocarcinoma A549 cells through a reactive oxygen species-dependent mitochondrial signaling pathway

Oncology Reports

Volumn 23, Issue 2, 2010, Pages 397-403

  Chen, Qingyong ^a,b   Wang, Yanyi ^c   Xu, Kedi ^d   Lu, Guohua ^a   Ying, Zheng ^b   Wu, Lijun ^b   Zhan, Jianwei ^b   Fang, Rui ^b   Wu, Yuquan ^b   Zhou, Jianying ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b The 117th Hospital of Chinese PLA   (China)

^c GUIZHOU UNIVERSITY   (China)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

Apoptosis; Curcumin; Lung cancer; MAPK; Mitochondrial membrane potential; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CURCUMIN; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CELL DEATH; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG EFFECT; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ADENOCARCINOMA; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CURCUMIN; DRUG EVALUATION, PRECLINICAL; HUMANS; LUNG NEOPLASMS; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 76649091631     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00000648     Document Type: Article

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