Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit cancer cell invasion through the down-regulation of MMPs and uPA

Journal of Nutritional Biochemistry

Volumn 20, Issue 2, 2009, Pages 87-95

  Yodkeeree, Supachai ^a   Chaiwangyen, Wittaya ^a   Garbisa, Spiridione ^b   Limtrakul, Pornngarm ^a  

^a Faculty of Medicine Chiang Mai University   (Thailand)

^b UNIVERSITY OF PADOVA   (Italy)

Author keywords

Bisdemethoxycurcumin; Cancer invasion; Curcuminoids; Matrix metalloproteinases (MMPs)

Indexed keywords

CURCUMIN; DEMETHOXYCURCUMIN; DIDEMETHOXYCURCUMIN; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; PROTEIN MT1 MMP; PROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG; UROKINASE;

ARTICLE; CANCER INHIBITION; CANCER INVASION; CELL MIGRATION; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG INHIBITION; DRUG STRUCTURE; ENZYME ACTIVATION; FIBROSARCOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; WESTERN BLOTTING; ZYMOGRAPHY;

3T3 CELLS; ANIMALS; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; CURCUMIN; FIBROSARCOMA; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MATRIX METALLOPROTEINASES; MICE; NEOPLASM INVASIVENESS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

CURCUMA LONGA;

EID: 58149119999     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2007.12.003     Document Type: Article

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