1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) facilitates curcumin-induced melanoma cell apoptosis by enhancing ceramide accumulation, JNK activation, and inhibiting PI3K/AKT activation.

Molecular and cellular biochemistry

Volumn 361, Issue 1-2, 2012, Pages 47-54

  Yu, Teng ^a   Li, Jinchao ^b   Qiu, Ying ^b   Sun, Hui ^b  

^a JINING MEDICAL UNIVERSITY   (China)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

2 DECANOYLAMINO 3 MORPHOLINO 1 PHENYL 1 PROPANOL; ANTINEOPLASTIC AGENT; CERAMIDE; CURCUMIN; MORPHOLINE DERIVATIVE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; HUMAN; MELANOMA; METABOLISM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CERAMIDES; CURCUMIN; DRUG SYNERGISM; ENZYME ACTIVATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MELANOMA; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 85027936281     PISSN: None     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-1086-9     Document Type: Article

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