메뉴 건너뛰기




Volumn 60, Issue 1, 2014, Pages 1-7

Effects of interleukin-1 on cardiac fibroblast function: Relevance to post-myocardial infarction remodelling

Author keywords

Cardiac fibroblast; Interleukin 1; Myocardial infarction; Signal transduction pathways; Therapies

Indexed keywords

GELATINASE A; GELATINASE B; INTERLEUKIN 1; INTERLEUKIN 33; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE 16; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 84892506135     PISSN: 15371891     EISSN: 18793649     Source Type: Journal    
DOI: 10.1016/j.vph.2013.06.002     Document Type: Review
Times cited : (42)

References (85)
  • 1
    • 77951665667 scopus 로고    scopus 로고
    • Interleukin-1 blockade with Anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study)
    • Abbate A., Kontos M.C., Grizzard J.D., Biondi-Zoccai G.G., Van Tassell B.W., Robati R., et al. Interleukin-1 blockade with Anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study). Am J Cardiol 2010, 105:1371-1377.
    • (2010) Am J Cardiol , vol.105 , pp. 1371-1377
    • Abbate, A.1    Kontos, M.C.2    Grizzard, J.D.3    Biondi-Zoccai, G.G.4    Van Tassell, B.W.5    Robati, R.6
  • 2
    • 84876981024 scopus 로고    scopus 로고
    • Effects of interleukin-1 blockade with Anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial 2 (VCU-ART2) Pilot Study]
    • Abbate A., Van Tassell B.W., Biondi-Zoccai G., Kontos M.C., Grizzard J.D., Spillman D.W., et al. Effects of interleukin-1 blockade with Anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial 2 (VCU-ART2) Pilot Study]. Am J Cardiol 2013, 111:1394-1400.
    • (2013) Am J Cardiol , vol.111 , pp. 1394-1400
    • Abbate, A.1    Van Tassell, B.W.2    Biondi-Zoccai, G.3    Kontos, M.C.4    Grizzard, J.D.5    Spillman, D.W.6
  • 3
    • 84863459500 scopus 로고    scopus 로고
    • Blocking interleukin-1 as a novel therapeutic strategy for secondary prevention of cardiovascular events
    • Abbate A., Van Tassell B.W., Biondi-Zoccai G.G. Blocking interleukin-1 as a novel therapeutic strategy for secondary prevention of cardiovascular events. BioDrugs 2012, 26:217-233.
    • (2012) BioDrugs , vol.26 , pp. 217-233
    • Abbate, A.1    Van Tassell, B.W.2    Biondi-Zoccai, G.G.3
  • 4
    • 77950279969 scopus 로고    scopus 로고
    • Interleukin-1beta modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse
    • Abbate A., Van Tassell B.W., Seropian I.M., Toldo S., Robati R., Varma A., et al. Interleukin-1beta modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse. Eur J Heart Fail 2010, 12:319-322.
    • (2010) Eur J Heart Fail , vol.12 , pp. 319-322
    • Abbate, A.1    Van Tassell, B.W.2    Seropian, I.M.3    Toldo, S.4    Robati, R.5    Varma, A.6
  • 5
    • 0032127279 scopus 로고    scopus 로고
    • Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
    • Adachi O., Kawai T., Takeda K., Matsumoto M., Tsutsui H., Sakagami M., et al. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 1998, 9:143-150.
    • (1998) Immunity , vol.9 , pp. 143-150
    • Adachi, O.1    Kawai, T.2    Takeda, K.3    Matsumoto, M.4    Tsutsui, H.5    Sakagami, M.6
  • 6
    • 47249089097 scopus 로고    scopus 로고
    • IL-1, IL-18, and IL-33 families of cytokines
    • Arend W.P., Palmer G., Gabay C. IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 2008, 223:20-38.
    • (2008) Immunol Rev , vol.223 , pp. 20-38
    • Arend, W.P.1    Palmer, G.2    Gabay, C.3
  • 8
    • 34548423254 scopus 로고    scopus 로고
    • Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse
    • Banerjee I., Fuseler J.W., Price R.L., Borg T.K., Baudino T.A. Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse. Am J Physiol Heart Circ Physiol 2007, 293:H1883-H1891.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Banerjee, I.1    Fuseler, J.W.2    Price, R.L.3    Borg, T.K.4    Baudino, T.A.5
  • 9
    • 70350741514 scopus 로고    scopus 로고
    • Myeloid differentiation factor-88/interleukin-1 signaling controls cardiac fibrosis and heart failure progression in inflammatory dilated cardiomyopathy
    • Blyszczuk P., Kania G., Dieterle T., Marty R.R., Valaperti A., Berthonneche C., et al. Myeloid differentiation factor-88/interleukin-1 signaling controls cardiac fibrosis and heart failure progression in inflammatory dilated cardiomyopathy. Circ Res 2009, 105:912-920.
    • (2009) Circ Res , vol.105 , pp. 912-920
    • Blyszczuk, P.1    Kania, G.2    Dieterle, T.3    Marty, R.R.4    Valaperti, A.5    Berthonneche, C.6
  • 10
    • 34848844641 scopus 로고    scopus 로고
    • Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components
    • Brikos C., Wait R., Begum S., O'Neill L.A., Saklatvala J. Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components. Mol Cell Proteomics 2007, 6:1551-1559.
    • (2007) Mol Cell Proteomics , vol.6 , pp. 1551-1559
    • Brikos, C.1    Wait, R.2    Begum, S.3    O'Neill, L.A.4    Saklatvala, J.5
  • 11
    • 13844312743 scopus 로고    scopus 로고
    • The cardiac fibroblast: therapeutic target in myocardial remodeling and failure
    • Brown R.D., Ambler S.K., Mitchell M.D., Long C.S. The cardiac fibroblast: therapeutic target in myocardial remodeling and failure. Annu Rev Pharmacol Toxicol 2005, 45:657-687.
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 657-687
    • Brown, R.D.1    Ambler, S.K.2    Mitchell, M.D.3    Long, C.S.4
  • 12
  • 13
    • 46749144616 scopus 로고    scopus 로고
    • Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling
    • Bujak M., Dobaczewski M., Chatila K., Mendoza L.H., Li N., Reddy A., et al. Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling. Am J Pathol 2008, 173:57-67.
    • (2008) Am J Pathol , vol.173 , pp. 57-67
    • Bujak, M.1    Dobaczewski, M.2    Chatila, K.3    Mendoza, L.H.4    Li, N.5    Reddy, A.6
  • 14
  • 15
    • 41649102599 scopus 로고    scopus 로고
    • Differential behaviors of atrial versus ventricular fibroblasts: a potential role for platelet-derived growth factor in atrial-ventricular remodeling differences
    • Burstein B., Libby E., Calderone A., Nattel S. Differential behaviors of atrial versus ventricular fibroblasts: a potential role for platelet-derived growth factor in atrial-ventricular remodeling differences. Circulation 2008, 117:1630-1641.
    • (2008) Circulation , vol.117 , pp. 1630-1641
    • Burstein, B.1    Libby, E.2    Calderone, A.3    Nattel, S.4
  • 16
    • 33744457045 scopus 로고    scopus 로고
    • Structural and functional coupling of cardiac myocytes and fibroblasts
    • Camelliti P., Green C.R., Kohl P. Structural and functional coupling of cardiac myocytes and fibroblasts. Adv Cardiol 2006, 42:132-149.
    • (2006) Adv Cardiol , vol.42 , pp. 132-149
    • Camelliti, P.1    Green, C.R.2    Kohl, P.3
  • 17
    • 34447116244 scopus 로고    scopus 로고
    • Identification of a key pathway required for the sterile inflammatory response triggered by dying cells
    • Chen C.J., Kono H., Golenbock D., Reed G., Akira S., Rock K.L. Identification of a key pathway required for the sterile inflammatory response triggered by dying cells. Nat Med 2007, 13:851-856.
    • (2007) Nat Med , vol.13 , pp. 851-856
    • Chen, C.J.1    Kono, H.2    Golenbock, D.3    Reed, G.4    Akira, S.5    Rock, K.L.6
  • 18
    • 84875069394 scopus 로고    scopus 로고
    • Fibroblasts in post-infarction inflammation and cardiac repair
    • Chen W., Frangogiannis N.G. Fibroblasts in post-infarction inflammation and cardiac repair. Biochim Biophys Acta 2013, 1833(4):945-953.
    • (2013) Biochim Biophys Acta , vol.1833 , Issue.4 , pp. 945-953
    • Chen, W.1    Frangogiannis, N.G.2
  • 19
    • 84871914561 scopus 로고    scopus 로고
    • Endogenous IRAK-M attenuates postinfarction remodeling through effects on macrophages and fibroblasts
    • Chen W., Saxena A., Li N., Sun J., Gupta A., Lee D.W., et al. Endogenous IRAK-M attenuates postinfarction remodeling through effects on macrophages and fibroblasts. Arterioscler Thromb Vasc Biol 2012, 32:2598-2608.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 2598-2608
    • Chen, W.1    Saxena, A.2    Li, N.3    Sun, J.4    Gupta, A.5    Lee, D.W.6
  • 20
    • 42349111723 scopus 로고    scopus 로고
    • Investigation of the effect of interleukin-1 receptor antagonist (IL-1ra) on markers of inflammation in non-ST elevation acute coronary syndromes (The MRC-ILA-HEART Study)
    • Crossman D.C., Morton A.C., Gunn J.P., Greenwood J.P., Hall A.S., Fox K.A., et al. Investigation of the effect of interleukin-1 receptor antagonist (IL-1ra) on markers of inflammation in non-ST elevation acute coronary syndromes (The MRC-ILA-HEART Study). Trials 2008, 9:8.
    • (2008) Trials , vol.9 , pp. 8
    • Crossman, D.C.1    Morton, A.C.2    Gunn, J.P.3    Greenwood, J.P.4    Hall, A.S.5    Fox, K.A.6
  • 21
    • 33644523710 scopus 로고    scopus 로고
    • MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics
    • Davis C.N., Mann E., Behrens M.M., Gaidarova S., Rebek M., Rebek J., et al. MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics. Proc Natl Acad Sci U S A 2006, 103:2953-2958.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2953-2958
    • Davis, C.N.1    Mann, E.2    Behrens, M.M.3    Gaidarova, S.4    Rebek, M.5    Rebek, J.6
  • 22
    • 84877011334 scopus 로고    scopus 로고
    • Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature
    • Demyanets S., Kaun C., Pentz R., Krychtiuk K.A., Rauscher S., Pfaffenberger S., et al. Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature. J Mol Cell Cardiol 2013, 60:16-26.
    • (2013) J Mol Cell Cardiol , vol.60 , pp. 16-26
    • Demyanets, S.1    Kaun, C.2    Pentz, R.3    Krychtiuk, K.A.4    Rauscher, S.5    Pfaffenberger, S.6
  • 23
    • 0036063690 scopus 로고    scopus 로고
    • Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats
    • Deten A., Volz H.C., Briest W., Zimmer H.G. Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats. Cardiovasc Res 2002, 55:329-340.
    • (2002) Cardiovasc Res , vol.55 , pp. 329-340
    • Deten, A.1    Volz, H.C.2    Briest, W.3    Zimmer, H.G.4
  • 24
    • 1542319857 scopus 로고    scopus 로고
    • Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction
    • Dewald O., Ren G., Duerr G.D., Zoerlein M., Klemm C., Gersch C., et al. Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction. Am J Pathol 2004, 164:665-677.
    • (2004) Am J Pathol , vol.164 , pp. 665-677
    • Dewald, O.1    Ren, G.2    Duerr, G.D.3    Zoerlein, M.4    Klemm, C.5    Gersch, C.6
  • 25
    • 22244475444 scopus 로고    scopus 로고
    • The many worlds of reducing interleukin-1
    • Dinarello C.A. The many worlds of reducing interleukin-1. Arthritis Rheum 2005, 52:1960-1967.
    • (2005) Arthritis Rheum , vol.52 , pp. 1960-1967
    • Dinarello, C.A.1
  • 26
    • 79953813107 scopus 로고    scopus 로고
    • Interleukin-1 in the pathogenesis and treatment of inflammatory diseases
    • Dinarello C.A. Interleukin-1 in the pathogenesis and treatment of inflammatory diseases. Blood 2011, 117:3720-3732.
    • (2011) Blood , vol.117 , pp. 3720-3732
    • Dinarello, C.A.1
  • 27
    • 84864545087 scopus 로고    scopus 로고
    • Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
    • Dinarello C.A., Simon A., van der Meer J.W. Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases. Nat Rev Drug Discov 2012, 11:633-652.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 633-652
    • Dinarello, C.A.1    Simon, A.2    van der Meer, J.W.3
  • 28
    • 84866521651 scopus 로고    scopus 로고
    • NOD1 activation induces cardiac dysfunction and modulates cardiac fibrosis and cardiomyocyte apoptosis
    • Fernandez-Velasco M., Prieto P., Terron V., Benito G., Flores J.M., Delgado C., et al. NOD1 activation induces cardiac dysfunction and modulates cardiac fibrosis and cardiomyocyte apoptosis. PLoS One 2012, 7:e45260.
    • (2012) PLoS One , vol.7
    • Fernandez-Velasco, M.1    Prieto, P.2    Terron, V.3    Benito, G.4    Flores, J.M.5    Delgado, C.6
  • 29
    • 78049431237 scopus 로고    scopus 로고
    • The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling
    • Flannery S., Bowie A.G. The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling. Biochem Pharmacol 2010, 80:1981-1991.
    • (2010) Biochem Pharmacol , vol.80 , pp. 1981-1991
    • Flannery, S.1    Bowie, A.G.2
  • 30
    • 53249095498 scopus 로고    scopus 로고
    • The immune system and cardiac repair
    • Frangogiannis N.G. The immune system and cardiac repair. Pharmacol Res 2008, 58:88-111.
    • (2008) Pharmacol Res , vol.58 , pp. 88-111
    • Frangogiannis, N.G.1
  • 31
    • 79955605472 scopus 로고    scopus 로고
    • Multiple facets of NF-κB in the heart: to be or not to NF-κB
    • Gordon J.W., Shaw J.A., Kirshenbaum L.A. Multiple facets of NF-κB in the heart: to be or not to NF-κB. Circ Res 2011, 108:1122-1132.
    • (2011) Circ Res , vol.108 , pp. 1122-1132
    • Gordon, J.W.1    Shaw, J.A.2    Kirshenbaum, L.A.3
  • 32
    • 0028835969 scopus 로고
    • Cytokine signaling during myocardial infarction: sequential appearance of IL-1 beta and IL-6
    • Guillen I., Blanes M., Gomez-Lechon M.J., Castell J.V. Cytokine signaling during myocardial infarction: sequential appearance of IL-1 beta and IL-6. Am J Physiol 1995, 269:R229-R235.
    • (1995) Am J Physiol , vol.269
    • Guillen, I.1    Blanes, M.2    Gomez-Lechon, M.J.3    Castell, J.V.4
  • 33
    • 43049159105 scopus 로고    scopus 로고
    • Imidaprilat inhibits matrix metalloproteinase-2 activity in human cardiac fibroblasts induced by interleukin-1β via NO-dependent pathway
    • Guo X.G., Uzui H., Mizuguchi T., Ueda T., Chen J.Z., Lee J.D. Imidaprilat inhibits matrix metalloproteinase-2 activity in human cardiac fibroblasts induced by interleukin-1β via NO-dependent pathway. Int J Cardiol 2008, 126:414-420.
    • (2008) Int J Cardiol , vol.126 , pp. 414-420
    • Guo, X.G.1    Uzui, H.2    Mizuguchi, T.3    Ueda, T.4    Chen, J.Z.5    Lee, J.D.6
  • 34
    • 18844458509 scopus 로고    scopus 로고
    • The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning
    • Hausenloy D.J., Tsang A., Yellon D.M. The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning. Trends Cardiovasc Med 2005, 15:69-75.
    • (2005) Trends Cardiovasc Med , vol.15 , pp. 69-75
    • Hausenloy, D.J.1    Tsang, A.2    Yellon, D.M.3
  • 35
    • 80054917317 scopus 로고    scopus 로고
    • A physiological concentration of glucocorticoid inhibits the pro-inflammatory cytokine-induced proliferation of adult rat cardiac fibroblasts: roles of extracellular signal-regulated kinase 1/2 and nuclear factor-kappaB
    • He Y.H., Zhang H.N., Zhang G.P., Hou N., Xiao Q., Huang Y., et al. A physiological concentration of glucocorticoid inhibits the pro-inflammatory cytokine-induced proliferation of adult rat cardiac fibroblasts: roles of extracellular signal-regulated kinase 1/2 and nuclear factor-kappaB. Clin Exp Pharmacol Physiol 2011, 38:739-746.
    • (2011) Clin Exp Pharmacol Physiol , vol.38 , pp. 739-746
    • He, Y.H.1    Zhang, H.N.2    Zhang, G.P.3    Hou, N.4    Xiao, Q.5    Huang, Y.6
  • 36
    • 0035654297 scopus 로고    scopus 로고
    • Myocardial hypertrophy in transgenic mice overexpressing human interleukin 1α
    • Isoda K., Kamezawa Y., Tada N., Sato M., Ohsuzu F. Myocardial hypertrophy in transgenic mice overexpressing human interleukin 1α. J Card Fail 2001, 7:355-364.
    • (2001) J Card Fail , vol.7 , pp. 355-364
    • Isoda, K.1    Kamezawa, Y.2    Tada, N.3    Sato, M.4    Ohsuzu, F.5
  • 37
    • 0141653901 scopus 로고    scopus 로고
    • Ventricular remodeling after infarction and the extracellular collagen matrix: when is enough enough?
    • Jugdutt B.I. Ventricular remodeling after infarction and the extracellular collagen matrix: when is enough enough?. Circulation 2003, 108:1395-1403.
    • (2003) Circulation , vol.108 , pp. 1395-1403
    • Jugdutt, B.I.1
  • 38
    • 79951679204 scopus 로고    scopus 로고
    • Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury
    • Kawaguchi M., Takahashi M., Hata T., Kashima Y., Usui F., Morimoto H., et al. Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury. Circulation 2011, 123:594-604.
    • (2011) Circulation , vol.123 , pp. 594-604
    • Kawaguchi, M.1    Takahashi, M.2    Hata, T.3    Kashima, Y.4    Usui, F.5    Morimoto, H.6
  • 39
    • 78649526043 scopus 로고    scopus 로고
    • Interleukin-32α production is regulated by MyD88-dependent and independent pathways in IL-1β-stimulated human alveolar epithelial cells
    • Ko N.Y., Mun S.H., Lee S.H., Kim J.W., Kim d.K., Kim H.S., et al. Interleukin-32α production is regulated by MyD88-dependent and independent pathways in IL-1β-stimulated human alveolar epithelial cells. Immunobiology 2011, 216:32-40.
    • (2011) Immunobiology , vol.216 , pp. 32-40
    • Ko, N.Y.1    Mun, S.H.2    Lee, S.H.3    Kim, J.W.4    Kim, D.5    Kim, H.S.6
  • 40
    • 0032476045 scopus 로고    scopus 로고
    • Cardiac fibroblasts arrest at the G1/S restriction point in response to interleukin (IL)-1β. Evidence for IL-1β-induced hypophosphorylation of the retinoblastoma protein
    • Koudssi F., Lopez J.E., Villegas S., Long C.S. Cardiac fibroblasts arrest at the G1/S restriction point in response to interleukin (IL)-1β. Evidence for IL-1β-induced hypophosphorylation of the retinoblastoma protein. J Biol Chem 1998, 273:25796-25803.
    • (1998) J Biol Chem , vol.273 , pp. 25796-25803
    • Koudssi, F.1    Lopez, J.E.2    Villegas, S.3    Long, C.S.4
  • 41
    • 77957729712 scopus 로고    scopus 로고
    • The origin of fibroblasts and mechanism of cardiac fibrosis
    • Krenning G., Zeisberg E.M., Kalluri R. The origin of fibroblasts and mechanism of cardiac fibrosis. J Cell Physiol 2010, 225:631-637.
    • (2010) J Cell Physiol , vol.225 , pp. 631-637
    • Krenning, G.1    Zeisberg, E.M.2    Kalluri, R.3
  • 43
    • 79952159132 scopus 로고    scopus 로고
    • Emerging inflammasome effector mechanisms
    • Lamkanfi M. Emerging inflammasome effector mechanisms. Nat Rev Immunol 2011, 11:213-220.
    • (2011) Nat Rev Immunol , vol.11 , pp. 213-220
    • Lamkanfi, M.1
  • 44
    • 0034925481 scopus 로고    scopus 로고
    • Decreased p38 MAPK activity in end-stage failing human myocardium: p38 MAPK α is the predominant isoform expressed in human heart
    • Lemke L.E., Bloem L.J., Fouts R., Esterman M., Sandusky G., Vlahos C.J. Decreased p38 MAPK activity in end-stage failing human myocardium: p38 MAPK α is the predominant isoform expressed in human heart. J Mol Cell Cardiol 2001, 33:1527-1540.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 1527-1540
    • Lemke, L.E.1    Bloem, L.J.2    Fouts, R.3    Esterman, M.4    Sandusky, G.5    Vlahos, C.J.6
  • 45
    • 0035063678 scopus 로고    scopus 로고
    • The role of interleukin-1 in the failing heart
    • Long C.S. The role of interleukin-1 in the failing heart. Heart Fail Rev 2001, 6:81-94.
    • (2001) Heart Fail Rev , vol.6 , pp. 81-94
    • Long, C.S.1
  • 46
    • 84876856286 scopus 로고    scopus 로고
    • Interleukin-1 has opposing effects on connective tissue growth factor and tenascin-C expression in human cardiac fibroblasts
    • Maqbool A., Hemmings K.E., O'Regan D.J., Ball S.G., Porter K.E., Turner N.A. Interleukin-1 has opposing effects on connective tissue growth factor and tenascin-C expression in human cardiac fibroblasts. Matrix Biol 2013, 32:208-214.
    • (2013) Matrix Biol , vol.32 , pp. 208-214
    • Maqbool, A.1    Hemmings, K.E.2    O'Regan, D.J.3    Ball, S.G.4    Porter, K.E.5    Turner, N.A.6
  • 47
    • 80052787378 scopus 로고    scopus 로고
    • The p38 mitogen-activated protein kinase pathway-A potential target for intervention in infarction, hypertrophy, and heart failure
    • Marber M.S., Rose B., Wang Y. The p38 mitogen-activated protein kinase pathway-A potential target for intervention in infarction, hypertrophy, and heart failure. J Mol Cell Cardiol 2011, 51:485-490.
    • (2011) J Mol Cell Cardiol , vol.51 , pp. 485-490
    • Marber, M.S.1    Rose, B.2    Wang, Y.3
  • 48
  • 50
    • 84872494961 scopus 로고    scopus 로고
    • Investigation of IL-1 inhibition in patients presenting with non-ST elevation myocardial infarction acute coronary syndromes (the MRC ILA Heart Study)
    • [abstract]
    • Morton A.C., Foley C., Rothman A., Gunn J., Greenwood J.P., Hall A., et al. Investigation of IL-1 inhibition in patients presenting with non-ST elevation myocardial infarction acute coronary syndromes (the MRC ILA Heart Study). Heart 2011, 97:A13. [abstract]. 10.1136/heartjnl-2011-300198.15.
    • (2011) Heart , vol.97
    • Morton, A.C.1    Foley, C.2    Rothman, A.3    Gunn, J.4    Greenwood, J.P.5    Hall, A.6
  • 51
    • 65349122338 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ-independent effects of thiazolidinediones on human cardiac myofibroblast function
    • Mughal R.S., Warburton P., O'Regan D.J., Ball S.G., Turner N.A., Porter K.E. Peroxisome proliferator-activated receptor γ-independent effects of thiazolidinediones on human cardiac myofibroblast function. Clin Exp Pharmacol Physiol 2009, 36:478-486.
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , pp. 478-486
    • Mughal, R.S.1    Warburton, P.2    O'Regan, D.J.3    Ball, S.G.4    Turner, N.A.5    Porter, K.E.6
  • 53
    • 46749136412 scopus 로고    scopus 로고
    • When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction
    • O'Neill L.A. When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction. Immunity 2008, 29:12-20.
    • (2008) Immunity , vol.29 , pp. 12-20
    • O'Neill, L.A.1
  • 54
    • 0028990133 scopus 로고
    • Interleukin-1β induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture
    • Palmer J.N., Hartogensis W.E., Patten M., Fortuin F.D., Long C.S. Interleukin-1β induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture. J Clin Invest 1995, 95:2555-2564.
    • (1995) J Clin Invest , vol.95 , pp. 2555-2564
    • Palmer, J.N.1    Hartogensis, W.E.2    Patten, M.3    Fortuin, F.D.4    Long, C.S.5
  • 55
    • 0032587449 scopus 로고    scopus 로고
    • Expression of Gi-2 alpha and Gs alpha in myofibroblasts localized to the infarct scar in heart failure due to myocardial infarction
    • Peterson D.J., Ju H., Hao J., Panagia M., Chapman D.C., Dixon I.M. Expression of Gi-2 alpha and Gs alpha in myofibroblasts localized to the infarct scar in heart failure due to myocardial infarction. Cardiovasc Res 1999, 41:575-585.
    • (1999) Cardiovasc Res , vol.41 , pp. 575-585
    • Peterson, D.J.1    Ju, H.2    Hao, J.3    Panagia, M.4    Chapman, D.C.5    Dixon, I.M.6
  • 57
    • 67249152096 scopus 로고    scopus 로고
    • Cardiac fibroblasts: at the heart of myocardial remodeling
    • Porter K.E., Turner N.A. Cardiac fibroblasts: at the heart of myocardial remodeling. Pharmacol Ther 2009, 123:255-278.
    • (2009) Pharmacol Ther , vol.123 , pp. 255-278
    • Porter, K.E.1    Turner, N.A.2
  • 59
    • 0034705240 scopus 로고    scopus 로고
    • Interleukin-1β and tumor necrosis factor-α decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro
    • Siwik D.A., Chang D.L., Colucci W.S. Interleukin-1β and tumor necrosis factor-α decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro. Circ Res 2000, 86:1259-1265.
    • (2000) Circ Res , vol.86 , pp. 1259-1265
    • Siwik, D.A.1    Chang, D.L.2    Colucci, W.S.3
  • 60
    • 84877711612 scopus 로고    scopus 로고
    • Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart
    • Strand M.E., Herum K.M., Rana Z.A., Skrbic B., Askevold E.T., Dahl C.P., et al. Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart. FEBS J 2013, 280:2228-2247.
    • (2013) FEBS J , vol.280 , pp. 2228-2247
    • Strand, M.E.1    Herum, K.M.2    Rana, Z.A.3    Skrbic, B.4    Askevold, E.T.5    Dahl, C.P.6
  • 61
    • 84857956806 scopus 로고    scopus 로고
    • Regression of cardiac hypertrophy by granulocyte colony-stimulating factor-stimulated interleukin-1β synthesis
    • Szardien S., Nef H.M., Voss S., Troidl C., Liebetrau C., Hoffmann J., et al. Regression of cardiac hypertrophy by granulocyte colony-stimulating factor-stimulated interleukin-1β synthesis. Eur Heart J 2012, 33:595-605.
    • (2012) Eur Heart J , vol.33 , pp. 595-605
    • Szardien, S.1    Nef, H.M.2    Voss, S.3    Troidl, C.4    Liebetrau, C.5    Hoffmann, J.6
  • 62
    • 41149165830 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction
    • Timmers L., Sluijter J.P., van Keulen J.K., Hoefer I.E., Nederhoff M.G., Goumans M.J., et al. Toll-like receptor 4 mediates maladaptive left ventricular remodeling and impairs cardiac function after myocardial infarction. Circ Res 2008, 102:257-264.
    • (2008) Circ Res , vol.102 , pp. 257-264
    • Timmers, L.1    Sluijter, J.P.2    van Keulen, J.K.3    Hoefer, I.E.4    Nederhoff, M.G.5    Goumans, M.J.6
  • 64
    • 80053098655 scopus 로고    scopus 로고
    • Therapeutic regulation of cardiac fibroblast function: targeting stress-activated protein kinase pathways
    • Turner N.A. Therapeutic regulation of cardiac fibroblast function: targeting stress-activated protein kinase pathways. Future Cardiol 2011, 7:673-691.
    • (2011) Future Cardiol , vol.7 , pp. 673-691
    • Turner, N.A.1
  • 65
    • 80052264672 scopus 로고    scopus 로고
    • Human cardiac fibroblasts express ICAM-1, E-selectin and CXC chemokines in response to proinflammatory cytokine stimulation
    • Turner N.A., Das A., O'Regan D.J., Ball S.G., Porter K.E. Human cardiac fibroblasts express ICAM-1, E-selectin and CXC chemokines in response to proinflammatory cytokine stimulation. Int J Biochem Cell Biol 2011, 43:1450-1458.
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 1450-1458
    • Turner, N.A.1    Das, A.2    O'Regan, D.J.3    Ball, S.G.4    Porter, K.E.5
  • 67
    • 34548452154 scopus 로고    scopus 로고
    • Mechanism of TNFα-induced IL-1α, IL-1β and IL-6 expression in human cardiac fibroblasts: effects of statins and thiazolidinediones
    • Turner N.A., Mughal R.S., Warburton P., O'Regan D.J., Ball S.G., Porter K.E. Mechanism of TNFα-induced IL-1α, IL-1β and IL-6 expression in human cardiac fibroblasts: effects of statins and thiazolidinediones. Cardiovasc Res 2007, 76:81-90.
    • (2007) Cardiovasc Res , vol.76 , pp. 81-90
    • Turner, N.A.1    Mughal, R.S.2    Warburton, P.3    O'Regan, D.J.4    Ball, S.G.5    Porter, K.E.6
  • 68
    • 84855871250 scopus 로고    scopus 로고
    • Regulation of myocardial matrix metalloproteinase expression and activity by cardiac fibroblasts
    • Turner N.A., Porter K.E. Regulation of myocardial matrix metalloproteinase expression and activity by cardiac fibroblasts. IUBMB Life 2012, 64:143-150.
    • (2012) IUBMB Life , vol.64 , pp. 143-150
    • Turner, N.A.1    Porter, K.E.2
  • 69
    • 84874958737 scopus 로고    scopus 로고
    • Function and fate of myofibroblasts after myocardial infarction
    • Turner N.A., Porter K.E. Function and fate of myofibroblasts after myocardial infarction. Fibrogenesis Tissue Repair 2013, 6:5.
    • (2013) Fibrogenesis Tissue Repair , vol.6 , pp. 5
    • Turner, N.A.1    Porter, K.E.2
  • 70
    • 77957752656 scopus 로고    scopus 로고
    • Modulatory effect of interleukin-1α on expression of structural matrix proteins, MMPs and TIMPs in human cardiac myofibroblasts: role of p38 MAP kinase
    • Turner N.A., Warburton P., O'Regan D.J., Ball S.G., Porter K.E. Modulatory effect of interleukin-1α on expression of structural matrix proteins, MMPs and TIMPs in human cardiac myofibroblasts: role of p38 MAP kinase. Matrix Biol 2010, 29:613-620.
    • (2010) Matrix Biol , vol.29 , pp. 613-620
    • Turner, N.A.1    Warburton, P.2    O'Regan, D.J.3    Ball, S.G.4    Porter, K.E.5
  • 72
    • 84889086804 scopus 로고    scopus 로고
    • Combined effects of interleukin-1α and transforming growth factor-β1 on modulation of human cardiac fibroblast function
    • [in press]
    • van Nieuwenhoven F.A., Hemmings K.E., Porter K.E., Turner N.A. Combined effects of interleukin-1α and transforming growth factor-β1 on modulation of human cardiac fibroblast function. Matrix Biol 2013, [in press]. 10.1016/j.matbio.2013.03.008.
    • (2013) Matrix Biol
    • van Nieuwenhoven, F.A.1    Hemmings, K.E.2    Porter, K.E.3    Turner, N.A.4
  • 73
    • 84874969415 scopus 로고    scopus 로고
    • The role of cardiac fibroblasts in the transition from inflammation to fibrosis following myocardial infarction
    • van Nieuwenhoven F.A., Turner N.A. The role of cardiac fibroblasts in the transition from inflammation to fibrosis following myocardial infarction. Vascul Pharmacol 2013, 58:182-188.
    • (2013) Vascul Pharmacol , vol.58 , pp. 182-188
    • van Nieuwenhoven, F.A.1    Turner, N.A.2
  • 74
    • 77649290682 scopus 로고    scopus 로고
    • Interleukin-1 trap attenuates cardiac remodeling after experimental acute myocardial infarction in mice
    • Van Tassell B.W., Varma A., Salloum F.N., Das A., Seropian I.M., Toldo S., et al. Interleukin-1 trap attenuates cardiac remodeling after experimental acute myocardial infarction in mice. J Cardiovasc Pharmacol 2010, 55:117-122.
    • (2010) J Cardiovasc Pharmacol , vol.55 , pp. 117-122
    • Van Tassell, B.W.1    Varma, A.2    Salloum, F.N.3    Das, A.4    Seropian, I.M.5    Toldo, S.6
  • 77
    • 34547096488 scopus 로고    scopus 로고
    • Endotoxin-activated cultured neonatal rat cardiomyocytes express functional surface-associated interleukin-1α
    • Westphal E., Li C., Pilowski C., Koch S., Ebelt H., Muller-Werdan U., et al. Endotoxin-activated cultured neonatal rat cardiomyocytes express functional surface-associated interleukin-1α. J Endotoxin Res 2007, 13:25-34.
    • (2007) J Endotoxin Res , vol.13 , pp. 25-34
    • Westphal, E.1    Li, C.2    Pilowski, C.3    Koch, S.4    Ebelt, H.5    Muller-Werdan, U.6
  • 78
    • 0028173386 scopus 로고
    • The alpha-smooth muscle actin-positive cells in healing human myocardial scars
    • Willems I.E., Havenith M.G., De Mey J.G., Daemen M.J. The alpha-smooth muscle actin-positive cells in healing human myocardial scars. Am J Pathol 1994, 145:868-875.
    • (1994) Am J Pathol , vol.145 , pp. 868-875
    • Willems, I.E.1    Havenith, M.G.2    De Mey, J.G.3    Daemen, M.J.4
  • 79
    • 67249143445 scopus 로고    scopus 로고
    • Interleukin-1β inhibits collagen synthesis and promotes its decomposition in cultured cardiac fibroblasts
    • Xiao H., Ji A.M., Li Z.L., Song X.D., Su D., Chen A.H. Interleukin-1β inhibits collagen synthesis and promotes its decomposition in cultured cardiac fibroblasts. Sheng Li Xue Bao 2008, 60:355-361.
    • (2008) Sheng Li Xue Bao , vol.60 , pp. 355-361
    • Xiao, H.1    Ji, A.M.2    Li, Z.L.3    Song, X.D.4    Su, D.5    Chen, A.H.6
  • 80
    • 4544281016 scopus 로고    scopus 로고
    • Differential regulation of matrix metalloproteinase-2 and -9 expression and activity in adult rat cardiac fibroblasts in response to interleukin-1β
    • Xie Z., Singh M., Singh K. Differential regulation of matrix metalloproteinase-2 and -9 expression and activity in adult rat cardiac fibroblasts in response to interleukin-1β. J Biol Chem 2004, 279:39513-39519.
    • (2004) J Biol Chem , vol.279 , pp. 39513-39519
    • Xie, Z.1    Singh, M.2    Singh, K.3
  • 81
    • 77951702276 scopus 로고    scopus 로고
    • Distinctive ERK and p38 signaling in remote and infarcted myocardium during post-MI remodeling in the mouse
    • Yeh C.C., Li H., Malhotra D., Turcato S., Nicholas S., Tu R., et al. Distinctive ERK and p38 signaling in remote and infarcted myocardium during post-MI remodeling in the mouse. J Cell Biochem 2010, 109:1185-1191.
    • (2010) J Cell Biochem , vol.109 , pp. 1185-1191
    • Yeh, C.C.1    Li, H.2    Malhotra, D.3    Turcato, S.4    Nicholas, S.5    Tu, R.6
  • 82
    • 78650358123 scopus 로고    scopus 로고
    • Origins of cardiac fibroblasts
    • Zeisberg E.M., Kalluri R. Origins of cardiac fibroblasts. Circ Res 2010, 107:1304-1312.
    • (2010) Circ Res , vol.107 , pp. 1304-1312
    • Zeisberg, E.M.1    Kalluri, R.2
  • 83
    • 0035204105 scopus 로고    scopus 로고
    • Differential vulnerability to oxidative stress in rat cardiac myocytes versus fibroblasts
    • Zhang X., Azhar G., Nagano K., Wei J.Y. Differential vulnerability to oxidative stress in rat cardiac myocytes versus fibroblasts. J Am Coll Cardiol 2001, 38:2055-2062.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 2055-2062
    • Zhang, X.1    Azhar, G.2    Nagano, K.3    Wei, J.Y.4
  • 84
    • 0035938195 scopus 로고    scopus 로고
    • Release of pro- and anti-angiogenic factors by human cardiac fibroblasts: effects on DNA synthesis and protection under hypoxia in human endothelial cells
    • Zhao L., Eghbali-Webb M. Release of pro- and anti-angiogenic factors by human cardiac fibroblasts: effects on DNA synthesis and protection under hypoxia in human endothelial cells. Biochim Biophys Acta 2001, 1538:273-282.
    • (2001) Biochim Biophys Acta , vol.1538 , pp. 273-282
    • Zhao, L.1    Eghbali-Webb, M.2
  • 85
    • 81755161381 scopus 로고    scopus 로고
    • Cell death, damage-associated molecular patterns, and sterile inflammation in cardiovascular disease
    • Zheng Y., Gardner S.E., Clarke M.C. Cell death, damage-associated molecular patterns, and sterile inflammation in cardiovascular disease. Arterioscler Thromb Vasc Biol 2011, 31:2781-2786.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2781-2786
    • Zheng, Y.1    Gardner, S.E.2    Clarke, M.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.