Myeloid differentiation factor-88/interleukin-1 signaling controls cardiac fibrosis and heart failure progression in inflammatory dilated cardiomyopathy

Circulation Research

Volumn 105, Issue 9, 2009, Pages 912-920

  Blyszczuk, Przemyslaw ^a,b   Kania, Gabriela ^a,b   Dieterle, Thomas ^c   Marty, Rene R ^a,b   Valaperti, Alan ^a,b   Berthonneche, Corinne ^d   Pedrazzini, Thierry ^d   Berger, Christoph T ^a,b   Dirnhofer, Stephan ^e   Matter, Christian M ^a,b   Penninger, Josef M ^f   Lüscher, Thomas F ^a,b   Eriksson, Urs ^a,b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c Department of Internal Medicine   (Bulgaria)

^d UNIVERSITY HOSPITAL BASEL   (Switzerland)

^e UNIVERSITY OF LAUSANNE   (Switzerland)

^f ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

Autoimmune myocarditis; Fibrosis; Heart failure; Innate immunity

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR TYPE I; MYELOID DIFFERENTIATION FACTOR 88; ENHANCED GREEN FLUORESCENT PROTEIN; FREUND ADJUVANT; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 1BETA; MYD88 PROTEIN, MOUSE; MYOSIN HEAVY CHAIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DISEASE COURSE; FIBROBLAST; HEART FAILURE; HEART MUSCLE FIBROSIS; MOUSE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; ANIMAL; AUTOIMMUNITY; BAGG ALBINO MOUSE; BONE MARROW TRANSPLANTATION; C57BL MOUSE; CELL CULTURE; DENDRITIC CELL; DISEASE MODEL; FIBROSIS; GENETICS; HEART MUSCLE; HISTOCOMPATIBILITY; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MOUSE MUTANT; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; TRANSGENIC MOUSE; TRANSPLANTATION;

ANIMALS; AUTOIMMUNITY; BONE MARROW TRANSPLANTATION; CARDIOMYOPATHY, DILATED; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FIBROBLASTS; FIBROSIS; FREUND'S ADJUVANT; GREEN FLUORESCENT PROTEINS; HEART FAILURE; IMMUNITY, INNATE; INTERLEUKIN-1BETA; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYELOID DIFFERENTIATION FACTOR 88; MYOCARDITIS; MYOCARDIUM; MYOSIN HEAVY CHAINS; PHENOTYPE; RECEPTORS, INTERLEUKIN-1 TYPE I; SIGNAL TRANSDUCTION; TRANSPLANTATION CHIMERA;

EID: 70350741514     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.199802     Document Type: Article

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