-
1
-
-
74549206702
-
How the noninflammasome NLRs function in the innate immune system
-
Ting JP, Duncan JA, Lei Y, (2010) How the noninflammasome NLRs function in the innate immune system. Science 327: 286-290.
-
(2010)
Science
, vol.327
, pp. 286-290
-
-
Ting, J.P.1
Duncan, J.A.2
Lei, Y.3
-
2
-
-
33845595623
-
Innate immunity and inflammation: New frontiers in comparative cardiovascular pathology
-
Linde A, Mosier D, Blecha F, Melgarejo T, (2007) Innate immunity and inflammation: New frontiers in comparative cardiovascular pathology. Cardiovasc Res 73: 26-36.
-
(2007)
Cardiovasc Res
, vol.73
, pp. 26-36
-
-
Linde, A.1
Mosier, D.2
Blecha, F.3
Melgarejo, T.4
-
3
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway CA Jr, (1997) A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388: 394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
4
-
-
0035910010
-
Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL
-
Xu XH, Shah PK, Faure E, Equils O, Thomas L, et al. (2001) Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation 104: 3103-3108.
-
(2001)
Circulation
, vol.104
, pp. 3103-3108
-
-
Xu, X.H.1
Shah, P.K.2
Faure, E.3
Equils, O.4
Thomas, L.5
-
5
-
-
57749177662
-
The role of Toll-like receptors 3 and 9 in the development of autoimmune diabetes in NOD mice
-
Wong FS, Hu C, Zhang L, Du W, Alexopoulou L, et al. (2008) The role of Toll-like receptors 3 and 9 in the development of autoimmune diabetes in NOD mice. Ann N Y Acad Sci 1150: 146-148.
-
(2008)
Ann N Y Acad Sci
, vol.1150
, pp. 146-148
-
-
Wong, F.S.1
Hu, C.2
Zhang, L.3
Du, W.4
Alexopoulou, L.5
-
6
-
-
0037066041
-
Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation
-
Edfeldt K, Swedenborg J, Hansson GK, Yan ZQ, (2002) Expression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activation. Circulation 105: 1158-1161.
-
(2002)
Circulation
, vol.105
, pp. 1158-1161
-
-
Edfeldt, K.1
Swedenborg, J.2
Hansson, G.K.3
Yan, Z.Q.4
-
7
-
-
70450189795
-
Inflammation in atherosclerosis: from pathophysiology to practice
-
Libby P, Ridker PM, Hansson GK, (2009) Inflammation in atherosclerosis: from pathophysiology to practice. J Am Coll Cardiol 54: 2129-2138.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. 2129-2138
-
-
Libby, P.1
Ridker, P.M.2
Hansson, G.K.3
-
8
-
-
0032701642
-
Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium
-
Frantz S, Kobzik L, Kim YD, Fukazawa R, Medzhitov R, et al. (1999) Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium. J Clin Invest 104: 271-280.
-
(1999)
J Clin Invest
, vol.104
, pp. 271-280
-
-
Frantz, S.1
Kobzik, L.2
Kim, Y.D.3
Fukazawa, R.4
Medzhitov, R.5
-
9
-
-
0842285548
-
Increased toll-like receptor 4 in the myocardium of patients requiring left ventricular assist devices
-
Birks EJ, Felkin LE, Banner NR, Khaghani A, Barton PJ, et al. (2004) Increased toll-like receptor 4 in the myocardium of patients requiring left ventricular assist devices. J Heart Lung Transplant 23: 228-235.
-
(2004)
J Heart Lung Transplant
, vol.23
, pp. 228-235
-
-
Birks, E.J.1
Felkin, L.E.2
Banner, N.R.3
Khaghani, A.4
Barton, P.J.5
-
10
-
-
33746028777
-
Intracellular pattern recognition receptors in the host response
-
Meylan E, Tschopp J, Karin M, (2006) Intracellular pattern recognition receptors in the host response. Nature 442: 39-44.
-
(2006)
Nature
, vol.442
, pp. 39-44
-
-
Meylan, E.1
Tschopp, J.2
Karin, M.3
-
11
-
-
35348932070
-
Intracellular NOD-like receptors in host defense and disease
-
Kanneganti TD, Lamkanfi M, Nunez G, (2007) Intracellular NOD-like receptors in host defense and disease. Immunity 27: 549-559.
-
(2007)
Immunity
, vol.27
, pp. 549-559
-
-
Kanneganti, T.D.1
Lamkanfi, M.2
Nunez, G.3
-
12
-
-
33846330896
-
Nod-like proteins in immunity, inflammation and disease
-
Fritz JH, Ferrero RL, Philpott DJ, Girardin SE, (2006) Nod-like proteins in immunity, inflammation and disease. Nat Immunol 7: 1250-1257.
-
(2006)
Nat Immunol
, vol.7
, pp. 1250-1257
-
-
Fritz, J.H.1
Ferrero, R.L.2
Philpott, D.J.3
Girardin, S.E.4
-
13
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara N, Ogura Y, Fontalba A, Gutierrez O, Pons F, et al. (2003) Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 278: 5509-5512.
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
Gutierrez, O.4
Pons, F.5
-
14
-
-
32444445124
-
Nod1-dependent control of tumor growth
-
da Silva Correia J, Miranda Y, Austin-Brown N, Hsu J, Mathison J, et al. (2006) Nod1-dependent control of tumor growth. Proc Natl Acad Sci USA 103: 1840-1845.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 1840-1845
-
-
da Silva Correia, J.1
Miranda, Y.2
Austin-Brown, N.3
Hsu, J.4
Mathison, J.5
-
15
-
-
33947379719
-
Regulation of Nod1-mediated signaling pathways
-
da Silva Correia J, Miranda Y, Leonard N, Hsu J, Ulevitch RJ, (2007) Regulation of Nod1-mediated signaling pathways. Cell Death Differ 14: 830-839.
-
(2007)
Cell Death Differ
, vol.14
, pp. 830-839
-
-
da Silva Correia, J.1
Miranda, Y.2
Leonard, N.3
Hsu, J.4
Ulevitch, R.J.5
-
16
-
-
0038824980
-
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
-
Chamaillard M, Hashimoto M, Horie Y, Masumoto J, Qiu S, et al. (2003) An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol 4: 702-707.
-
(2003)
Nat Immunol
, vol.4
, pp. 702-707
-
-
Chamaillard, M.1
Hashimoto, M.2
Horie, Y.3
Masumoto, J.4
Qiu, S.5
-
17
-
-
17644366913
-
NOD-LRR proteins: role in host-microbial interactions and inflammatory disease
-
Inohara N, Chamaillard M, McDonald C, Nunez G, (2005) NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu Rev Biochem 74: 355-383.
-
(2005)
Annu Rev Biochem
, vol.74
, pp. 355-383
-
-
Inohara, N.1
Chamaillard, M.2
McDonald, C.3
Nunez, G.4
-
18
-
-
34247239745
-
Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines
-
Uehara A, Fujimoto Y, Fukase K, Takada H, (2007) Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines. Mol Immunol 44: 3100-3111.
-
(2007)
Mol Immunol
, vol.44
, pp. 3100-3111
-
-
Uehara, A.1
Fujimoto, Y.2
Fukase, K.3
Takada, H.4
-
19
-
-
31944437924
-
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo
-
Masumoto J, Yang K, Varambally S, Hasegawa M, Tomlins SA, et al. (2006) Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo. J Exp Med 203: 203-213.
-
(2006)
J Exp Med
, vol.203
, pp. 203-213
-
-
Masumoto, J.1
Yang, K.2
Varambally, S.3
Hasegawa, M.4
Tomlins, S.A.5
-
20
-
-
77953707119
-
Nod proteins link bacterial sensing and autophagy
-
Travassos LH, Carneiro LA, Girardin S, Philpott DJ, (2010) Nod proteins link bacterial sensing and autophagy. Autophagy 6: 409-411.
-
(2010)
Autophagy
, vol.6
, pp. 409-411
-
-
Travassos, L.H.1
Carneiro, L.A.2
Girardin, S.3
Philpott, D.J.4
-
21
-
-
33947318655
-
Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo
-
Cartwright N, Murch O, McMaster SK, Paul-Clark MJ, van Heel DA, et al. (2007) Selective NOD1 agonists cause shock and organ injury/dysfunction in vivo. Am J Respir Crit Care Med 175: 595-603.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 595-603
-
-
Cartwright, N.1
Murch, O.2
McMaster, S.K.3
Paul-Clark, M.J.4
van Heel, D.A.5
-
22
-
-
80053628512
-
NOD-like receptors and RIG-I-like receptors in human eosinophils: activation by NOD1 and NOD2 agonists
-
Kvarnhammar AM, Petterson T, Cardell LO, (2011) NOD-like receptors and RIG-I-like receptors in human eosinophils: activation by NOD1 and NOD2 agonists. Immunology 134: 314-325.
-
(2011)
Immunology
, vol.134
, pp. 314-325
-
-
Kvarnhammar, A.M.1
Petterson, T.2
Cardell, L.O.3
-
23
-
-
59849125934
-
Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia
-
Fernandez-Velasco M, Rueda A, Rizzi N, Benitah JP, Colombi B, et al. (2009) Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia. Circ Res 104: 201-209.
-
(2009)
Circ Res
, vol.104
, pp. 201-209
-
-
Fernandez-Velasco, M.1
Rueda, A.2
Rizzi, N.3
Benitah, J.P.4
Colombi, B.5
-
24
-
-
11144346203
-
Structural and functional characterisation of cardiac fibroblasts
-
Camelliti P, Borg TK, Kohl P, (2005) Structural and functional characterisation of cardiac fibroblasts. Cardiovasc Res 65: 40-51.
-
(2005)
Cardiovasc Res
, vol.65
, pp. 40-51
-
-
Camelliti, P.1
Borg, T.K.2
Kohl, P.3
-
25
-
-
1942494484
-
Organization of fibroblasts in the heart
-
Goldsmith EC, Hoffman A, Morales MO, Potts JD, Price RL, et al. (2004) Organization of fibroblasts in the heart. Dev Dyn 230: 787-794.
-
(2004)
Dev Dyn
, vol.230
, pp. 787-794
-
-
Goldsmith, E.C.1
Hoffman, A.2
Morales, M.O.3
Potts, J.D.4
Price, R.L.5
-
26
-
-
0035951792
-
Human Nod1 confers responsiveness to bacterial lipopolysaccharides
-
Inohara N, Ogura Y, Chen FF, Muto A, Nunez G, (2001) Human Nod1 confers responsiveness to bacterial lipopolysaccharides. J Biol Chem 276: 2551-2554.
-
(2001)
J Biol Chem
, vol.276
, pp. 2551-2554
-
-
Inohara, N.1
Ogura, Y.2
Chen, F.F.3
Muto, A.4
Nunez, G.5
-
27
-
-
29644441714
-
NF-κB and activator protein 1 response elements and the role of histone modifications in IL-1β-induced TGF-β1 gene transcription
-
Lee KY, Ito K, Hayashi R, Jazrawi EP, Barnes PJ, et al. (2006) NF-κB and activator protein 1 response elements and the role of histone modifications in IL-1β-induced TGF-β1 gene transcription. J Immunol 176: 603-615.
-
(2006)
J Immunol
, vol.176
, pp. 603-615
-
-
Lee, K.Y.1
Ito, K.2
Hayashi, R.3
Jazrawi, E.P.4
Barnes, P.J.5
-
28
-
-
36448936383
-
TGFβ-SMAD signal transduction: molecular specificity and functional flexibility
-
Schmierer B, Hill CS, (2007) TGFβ-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol 8: 970-982.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 970-982
-
-
Schmierer, B.1
Hill, C.S.2
-
29
-
-
0033591330
-
Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-κB
-
Inohara N, Koseki T, del Peso L, Hu Y, Yee C, et al. (1999) Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-κB. J Biol Chem 274: 14560-14567.
-
(1999)
J Biol Chem
, vol.274
, pp. 14560-14567
-
-
Inohara, N.1
Koseki, T.2
del Peso, L.3
Hu, Y.4
Yee, C.5
-
30
-
-
73349122017
-
Cardiac fibroblast: the renaissance cell
-
Souders CA, Bowers SL, Baudino TA, (2009) Cardiac fibroblast: the renaissance cell. Circ Res 105: 1164-1176.
-
(2009)
Circ Res
, vol.105
, pp. 1164-1176
-
-
Souders, C.A.1
Bowers, S.L.2
Baudino, T.A.3
-
31
-
-
39349099135
-
Atrial fibrosis: mechanisms and clinical relevance in atrial fibrillation
-
Burstein B, Nattel S, (2008) Atrial fibrosis: mechanisms and clinical relevance in atrial fibrillation. J Am Coll Cardiol 51: 802-809.
-
(2008)
J Am Coll Cardiol
, vol.51
, pp. 802-809
-
-
Burstein, B.1
Nattel, S.2
-
32
-
-
34547535297
-
Mechanisms of disease: Toll-like receptors in cardiovascular disease
-
Frantz S, Ertl G, Bauersachs J, (2007) Mechanisms of disease: Toll-like receptors in cardiovascular disease. Nat Clin Pract Cardiovasc Med 4: 444-454.
-
(2007)
Nat Clin Pract Cardiovasc Med
, vol.4
, pp. 444-454
-
-
Frantz, S.1
Ertl, G.2
Bauersachs, J.3
-
33
-
-
0032988969
-
Early activation of transcription factor NF-κB during ischemia in perfused rat heart
-
Li C, Browder W, Kao RL, (1999) Early activation of transcription factor NF-κB during ischemia in perfused rat heart. Am J Physiol 276: H543-552.
-
(1999)
Am J Physiol
, vol.276
-
-
Li, C.1
Browder, W.2
Kao, R.L.3
-
34
-
-
0030855813
-
In vivo transfection of cis element "decoy" against nuclear factor-κB binding site prevents myocardial infarction
-
Morishita R, Sugimoto T, Aoki M, Kida I, Tomita N, et al. (1997) In vivo transfection of cis element "decoy" against nuclear factor-κB binding site prevents myocardial infarction. Nat Med 3: 894-899.
-
(1997)
Nat Med
, vol.3
, pp. 894-899
-
-
Morishita, R.1
Sugimoto, T.2
Aoki, M.3
Kida, I.4
Tomita, N.5
-
35
-
-
1142309739
-
Modulating Toll-like receptor mediated signaling by (1->3)-β-D-glucan rapidly induces cardioprotection
-
Li C, Ha T, Kelley J, Gao X, Qiu Y, et al. (2004) Modulating Toll-like receptor mediated signaling by (1->3)-β-D-glucan rapidly induces cardioprotection. Cardiovasc Res 61: 538-547.
-
(2004)
Cardiovasc Res
, vol.61
, pp. 538-547
-
-
Li, C.1
Ha, T.2
Kelley, J.3
Gao, X.4
Qiu, Y.5
-
36
-
-
34249787873
-
Protection against myocardial ischemia/reperfusion injury in TLR4-deficient mice is mediated through a phosphoinositide 3-kinase-dependent mechanism
-
Hua F, Ha T, Ma J, Li Y, Kelley J, et al. (2007) Protection against myocardial ischemia/reperfusion injury in TLR4-deficient mice is mediated through a phosphoinositide 3-kinase-dependent mechanism. J Immunol 178: 7317-7324.
-
(2007)
J Immunol
, vol.178
, pp. 7317-7324
-
-
Hua, F.1
Ha, T.2
Ma, J.3
Li, Y.4
Kelley, J.5
-
37
-
-
79955591866
-
Nod1 ligands induce site-specific vascular inflammation
-
Nishio H, Kanno S, Onoyama S, Ikeda K, Tanaka T, et al. (2011) Nod1 ligands induce site-specific vascular inflammation. Arterioscler Thromb Vasc Biol 31: 1093-1099.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 1093-1099
-
-
Nishio, H.1
Kanno, S.2
Onoyama, S.3
Ikeda, K.4
Tanaka, T.5
-
38
-
-
77954882468
-
Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages
-
Moreno L, McMaster SK, Gatheral T, Bailey LK, Harrington LS, et al. (2010) Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages. Br J Pharmacol 160: 1997-2007.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 1997-2007
-
-
Moreno, L.1
McMaster, S.K.2
Gatheral, T.3
Bailey, L.K.4
Harrington, L.S.5
-
39
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, et al. (2010) NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 464: 1357-1361.
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
-
40
-
-
20244364812
-
NOD1 variation, immunoglobulin E and asthma
-
Hysi P, Kabesch M, Moffatt MF, Schedel M, Carr D, et al. (2005) NOD1 variation, immunoglobulin E and asthma. Hum Mol Genet 14: 935-941.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 935-941
-
-
Hysi, P.1
Kabesch, M.2
Moffatt, M.F.3
Schedel, M.4
Carr, D.5
-
41
-
-
21344448610
-
Association of NOD1 polymorphisms with atopic eczema and related phenotypes
-
Weidinger S, Klopp N, Rummler L, Wagenpfeil S, Novak N, et al. (2005) Association of NOD1 polymorphisms with atopic eczema and related phenotypes. J Allergy Clin Immunol 116: 177-184.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 177-184
-
-
Weidinger, S.1
Klopp, N.2
Rummler, L.3
Wagenpfeil, S.4
Novak, N.5
-
42
-
-
17944380130
-
CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
-
Girardin SE, Tournebize R, Mavris M, Page AL, Li X, et al. (2001) CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri. EMBO Rep 2: 736-742.
-
(2001)
EMBO Rep
, vol.2
, pp. 736-742
-
-
Girardin, S.E.1
Tournebize, R.2
Mavris, M.3
Page, A.L.4
Li, X.5
-
43
-
-
34250888664
-
Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells
-
Park JH, Kim YG, Shaw M, Kanneganti TD, Fujimoto Y, et al. (2007) Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells. J Immunol 179: 514-521.
-
(2007)
J Immunol
, vol.179
, pp. 514-521
-
-
Park, J.H.1
Kim, Y.G.2
Shaw, M.3
Kanneganti, T.D.4
Fujimoto, Y.5
-
44
-
-
70149099161
-
XIAP mediates NOD signaling via interaction with RIP2
-
Krieg A, Correa RG, Garrison JB, Le Negrate G, Welsh K, et al. (2009) XIAP mediates NOD signaling via interaction with RIP2. Proc Natl Acad Sci U S A 106: 14524-14529.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14524-14529
-
-
Krieg, A.1
Correa, R.G.2
Garrison, J.B.3
Le Negrate, G.4
Welsh, K.5
-
45
-
-
33645806742
-
Fibrosis in heart disease: understanding the role of transforming growth factor-β in cardiomyopathy, valvular disease and arrhythmia
-
Khan R, Sheppard R, (2006) Fibrosis in heart disease: understanding the role of transforming growth factor-β in cardiomyopathy, valvular disease and arrhythmia. Immunology 118: 10-24.
-
(2006)
Immunology
, vol.118
, pp. 10-24
-
-
Khan, R.1
Sheppard, R.2
-
46
-
-
0032227612
-
Role of matrix proteases in processing enamel proteins
-
Woessner JF Jr, (1998) Role of matrix proteases in processing enamel proteins. Connect Tissue Res 39: 69-73.
-
(1998)
Connect Tissue Res
, vol.39
, pp. 69-73
-
-
Woessner Jr., J.F.1
|