Combined effects of interleukin-1α and transforming growth factor-β1 on modulation of human cardiac fibroblast function

Matrix Biology

Volumn 32, Issue 7-8, 2013, Pages 399-406

  van Nieuwenhoven, Frans A ^a   Hemmings, Karen E ^b   Porter, Karen E ^b   Turner, Neil A ^b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Cardiac fibroblasts; Cytokines; Extracellular matrix; Fibrosis; Inflammation; Remodeling

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN GEL; COLLAGEN TYPE 3; CONNECTIVE TISSUE GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; RECOMBINANT INTERLEUKIN 1ALPHA; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; SMAD3 PROTEIN; STROMELYSIN;

ARTICLE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FIBROBLAST; HEART ATRIUM APPENDAGE; HEART FUNCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALPHA-SMOOTH MUSCLE ACTIN; CARDIAC FIBROBLAST; CARDIAC FIBROBLASTS; CARDIAC MYOFIBROBLAST; CF; CMF; COL1A1; COL3A1; COLLAGEN I; COLLAGEN III; CONNECTIVE TISSUE GROWTH FACTOR; CTGF; CYTOKINES; ECM; EXTRACELLULAR MATRIX; FIBROSIS; IL; INFLAMMATION; INTERLEUKIN; MATRIX METALLOPROTEINASE; MMP; REMODELING; TGFΒ1; TNFΑ; TRANSFORMING GROWTH FACTOR Β1; TUMOR NECROSIS FACTOR Α; ΑSMA;

BLOTTING, WESTERN; COLLAGEN TYPE III; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1ALPHA; INTERLEUKIN-6; INTERLEUKIN-8; MATRIX METALLOPROTEINASE 3; MYOCARDIUM; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84889086804     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2013.03.008     Document Type: Article

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