Mechanism of TNFα-induced IL-1α, IL-1β and IL-6 expression in human cardiac fibroblasts: Effects of statins and thiazolidinediones

Cardiovascular Research

Volumn 76, Issue 1, 2007, Pages 81-90

  Turner, Neil A ^a   Mughal, Romana S ^a   Warburton, Philip ^a   O'Regan, David J ^b   Ball, Stephen G ^a   Porter, Karen E ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS GENERAL INFIRMARY   (United Kingdom)

Author keywords

Cytokines; Interleukins; Receptors; Signal transduction; Statins

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; CIGLITAZONE; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOSPECIFIC ANTIBODY; PROTEIN KINASE B; ROSIGLITAZONE; SIMVASTATIN; TROGLITAZONE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; CHROMAN DERIVATIVE; INDOLE DERIVATIVE; INTERLEUKIN DERIVATIVE; MONOCLONAL ANTIBODY; MONOUNSATURATED FATTY ACID;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CYTOKINE RELEASE; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; HEART; HEART ATRIUM APPENDAGE; HEART MUSCLE; HEART MUSCLE BIOPSY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; INTROSPECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; STIMULATION; ANALYSIS OF VARIANCE; BIOSYNTHESIS; CORONARY ARTERY DISEASE; DOSE RESPONSE; GENETICS; HEART MUSCLE CELL; IMMUNOLOGY; METHODOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANALYSIS OF VARIANCE; ANTIBODIES, MONOCLONAL; CELLS, CULTURED; CHROMANS; CORONARY DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FATTY ACIDS, MONOUNSATURATED; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INDOLES; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; INTERLEUKIN-6; INTERLEUKINS; MYOCYTES, CARDIAC; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SIMVASTATIN; STIMULATION, CHEMICAL; THIAZOLIDINEDIONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34548452154     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2007.06.003     Document Type: Article

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