Cisplatin associated with LY294002 increases cytotoxicity and induces changes in transcript profiles of glioblastoma cells

Molecular Biology Reports

Volumn 41, Issue 1, 2014, Pages 165-177

  Carminati, P O ^a   Donaires, F S ^a   Marques, M M ^a   Donadi, E A ^a   Passos, G A S ^a   Sakamoto Hojo, E T ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Cisplatin; DNA repair; DNA PK; Glioblastoma; LY294002; Microarrays

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ATM PROTEIN; ATR PROTEIN; CHECKPOINT KINASE 1; CISPLATIN; DNA DEPENDENT PROTEIN KINASE; HISTONE H2AX; PROTEIN P53;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER RESISTANCE; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG POTENTIATION; DRUG SENSITIVITY; GENE EXPRESSION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; PROTEIN PHOSPHORYLATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHROMONES; CISPLATIN; DNA DAMAGE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; GENE EXPRESSION PROFILING; GLIOBLASTOMA; HUMANS; MORPHOLINES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; TRANSCRIPTOME;

EID: 84891908024     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-013-2849-z     Document Type: Article

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