Sensitization of glioma cells by X-linked inhibitor of apoptosis protein knockdown

Oncology (Switzerland)

Volumn 83, Issue 2, 2012, Pages 75-82

  Lopez, Patricia L C ^a   Filippi Chiela, Eduardo C ^a   Silva, Andrew O ^a   Cordero, Elvira A A ^a   Garcia Santos, Daniel ^a   Pelegrini, Alessandra L ^a   Reder, Gleice M ^b   Barbieri, Nicolle L ^a   Lenz, Guido ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Apoptosis; Doxorubicin; Gliomas; Senescence; shRNA; Vincristine; XIAP

Indexed keywords

CARMUSTINE; CISPLATIN; DOXORUBICIN; ETOPOSIDE; PACLITAXEL; RESVERATROL; TEMOZOLOMIDE; VINCRISTINE; X LINKED INHIBITOR OF APOPTOSIS;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CELL VIABILITY; CHEMOTHERAPY; CONTROLLED STUDY; DNA DAMAGE; GENE OVEREXPRESSION; GENE SILENCING; GLIOMA CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; SENESCENCE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CELL AGING; CENTRAL NERVOUS SYSTEM NEOPLASMS; DNA DAMAGE; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; ETOPOSIDE; GENE KNOCKDOWN TECHNIQUES; GLIOMA; HUMANS; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; VINCRISTINE; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84863109641     PISSN: 00302414     EISSN: 14230232     Source Type: Journal    
DOI: 10.1159/000337978     Document Type: Article

References (44)

1. Van Meir EG, Hadjipanayis CG, Norden AD, Shu HK, Wen PY, Olson JJ: Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin 2010; 60: 166-193.
2. Cohen MH, Johnson JR, Pazdur R: Food and Drug Administration drug approval summary: temozolomide plus radiation therapy for the treatment of newly diagnosed glioblastoma multiforme. Clin Cancer Res 2005; 11: 6767-6771. (Pubitemid 41428729)
3. Gunther W, Pawlak E, Damasceno R, Arnold H, Terzis AJ: Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids. Br J Cancer 2003; 88: 463-469. (Pubitemid 36308160)
4. Natsumeda M, Aoki H, Miyahara H, Yajima N, Uzuka T, Toyoshima Y, Kakita A, Takahashi H, Fujii Y: Induction of autophagy in temozolomide treated malignant gliomas. Neuropathology 2011; 31: 486-493.
5. Gagnon V, Van Themsche C, Turner S, Leblanc V, Asselin E: Akt and XIAP regulate the sensitivity of human uterine cancer cells to cisplatin, doxorubicin and taxol. Apoptosis 2008; 13: 259-271.
6. Lima RT, Martins LM, Guimaraes JE, Sambade C, Vasconcelos MH: Specific downregulation of bcl-2 and xIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells. Cancer Gene Ther 2004; 11: 309-316. (Pubitemid 38586086)
7. Ma JJ, Chen BL, Xin XY: XIAP gene downregulation by small interfering RNA inhibits proliferation, induces apoptosis, and reverses the cisplatin resistance of ovarian carcinoma. Eur J Obstet Gynecol Reprod Biol 2009; 146: 222-226.
8. Pavet V, Portal MM, Moulin JC, Herbrecht R, Gronemeyer H: Towards novel paradigms for cancer therapy. Oncogene 2010; 30: 1-20.
9. Cancer Genome Atlas Research Network: Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008; 455: 1061-1068.
10. Vousden KH, Prives C: Blinded by the light: the growing complexity of p53. Cell 2009; 137: 413-431.
11. Molchadsky A, Rivlin N, Brosh R, Rotter V, Sarig R: p53 is balancing development, differentiation and de-differentiation to assure cancer prevention. Carcinogenesis 2010; 31: 1501-1508.
12. Cotter TG: Apoptosis and cancer: the genesis of a research field. Nat Rev Cancer 2009; 9: 501-507.
13. Nakamura H, Kumei Y, Morita S, Shimokawa H, Ohya K, Shinomiya K: Antagonism between apoptotic (Bax/Bcl-2) and antiapo- ptotic (IAP) signals in human osteoblastic cells under vector-averaged gravity condition. Ann NY Acad Sci 2003; 1010: 143-147. (Pubitemid 38264964)
14. Hunter AM, LaCasse EC, Korneluk RG: The inhibitors of apoptosis (IAPs) as cancer targets. Apoptosis 2007; 12: 1543-1568. (Pubitemid 47106887)
15. Wagenknecht B, Glaser T, Naumann U, Kugler S, Isenmann S, Bahr M, Korneluk R, Liston P, Weller M: Expression and biological activity of X-linked inhibitor of apoptosis (XIAP) in human malignant glioma. Cell Death Differ 1999; 6: 370-376. (Pubitemid 29186881)
16. Deveraux QL, Takahashi R, Salvesen GS, Reed JC: X-linked IAP is a direct inhibitor of cell-death proteases. Nature 1997; 388: 300-304. (Pubitemid 27317977)
17. Harlin H, Reffey SB, Duckett CS, Lindsten T, Thompson CB: Characterization of XIAPdeficient mice. Mol Cell Biol 2001; 21: 3604-3608.
18. Fulda S: Tumor resistance to apoptosis. Int J Cancer 2009; 124: 511-515.
19. Holcik M, Korneluk RG: XIAP, the guardian angel. Nat Rev Mol Cell Biol 2001; 2: 550-556. (Pubitemid 33673406)
20. Altieri DC: Survivin and apoptosis control. Adv Cancer Res 2003; 88: 31-52. (Pubitemid 36343278)
21. Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L: A third-generation lentivirus vector with a conditional packaging system. J Virol 1998; 72: 8463-8471. (Pubitemid 28471781)
22. Zamin LL, Filippi-Chiela EC, Dillenburg- Pilla P, Horn F, Salbego C, Lenz G: Resveratrol and quercetin cooperate to induce senescence- like growth arrest in C6 rat glioma cells. Cancer Sci 2009; 100: 1655-1662.
23. Baltes S, Freund I, Lewis AL, Nolte I, Brinker T: Doxorubicin and irinotecan drug-eluting beads for treatment of glioma: a pilot study in a rat model. J Mater Sci Mater Med 2010; 21: 1393-1402.
24. Lesniak MS, Upadhyay U, Goodwin R, Tyler B, Brem H: Local delivery of doxorubicin for the treatment of malignant brain tumors in rats. Anticancer Res 2005; 25: 3825-3831. (Pubitemid 41665151)
25. Kikuchi T, Saito R, Sugiyama S, Yamashita Y, Kumabe T, Krauze M, Bankiewicz K, Tominaga T: Convection-enhanced delivery of polyethylene glycol-coated liposomal doxorubicin: characterization and efficacy in rat intracranial glioma models. J Neurosurg 2008; 109: 867-873.
26. Verreault M, Strutt D, Masin D, Anantha M, Yung A, Kozlowski P, Waterhouse D, Bally MB, Yapp DT: Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C TM ), doxorubicin (Caelyx ) or vincristine. BMC Cancer 2011; 11: 124.
27. Rebbaa A, Zheng X, Chou PM, Mirkin BL: Caspase inhibition switches doxorubicin-induced apoptosis to senescence. Oncogene 2003; 22: 2805-2811. (Pubitemid 36609594)
28. Lenz G: The RNA interference revolution. Braz J Med Biol Res 2005; 38: 1749-1757. (Pubitemid 43078604)
29. Huszthy PC, Giroglou T, Tsinkalovsky O, Euskirchen P, Skaftnesmo KO, Bjerkvig R, von Laer D, Miletic H: Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy. PLoS One 2009; 4:e6314.
30. Miletic H, Fischer YH, Neumann H, Hans V, Stenzel W, Giroglou T, Hermann M, Deckert M, Von Laer D: Selective transduction of malignant glioma by lentiviral vectors pseudotyped with lymphocytic choriomeningitis virus glycoproteins. Hum Gene Ther 2004; 15: 1091-1100. (Pubitemid 39552290)
31. Carter BZ, Milella M, Tsao T, McQueen T, Schober WD, Hu W, Dean NM, Steelman L, McCubrey JA, Andreeff M: Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia. Leukemia 2003; 17: 2081-2089. (Pubitemid 37428371)
32. Spee B, Jonkers MD, Arends B, Rutteman GR, Rothuizen J, Penning LC: Specific down-regulation of XIAP with RNA interference enhances the sensitivity of canine tumor cell-lines to TRAIL and doxorubicin. Mol Cancer 2006; 5: 34.
33. McManus DC, Lefebvre CA, Cherton-Horvat G, St-Jean M, Kandimalla ER, Agrawal S, Morris SJ, Durkin JP, Lacasse EC: Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics. Oncogene 2004; 23: 8105-8117. (Pubitemid 39531851)
34. Vellanki SH, Grabrucker A, Liebau S, Proepper C, Eramo A, Braun V, Boeckers T, Debatin KM, Fulda S: Small-molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma. Neoplasia 2009; 11: 743-752.
35. Jeong JC, Kim MS, Kim TH, Kim YK: Kaempferol induces cell death through ERK and Akt-dependent down-regulation of XIAP and survivin in human glioma cells. Neurochem Res 2009; 34: 991-1001.
36. Kang DW, Choi CH, Park JY, Kang SK, Kim YK: Ciglitazone induces caspase-independent apoptosis through down-regulation of XIAP and survivin in human glioma cells. Neurochem Res 2008; 33: 551-561. (Pubitemid 351230459)
37. Kim EH, Kim SU, Shin DY, Choi KS: Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP. Oncogene 2004; 23: 446-456. (Pubitemid 38174999)
38. Kim EH, Kim HS, Kim SU, Noh EJ, Lee JS, Choi KS: Sodium butyrate sensitizes human glioma cells to TRAIL-mediated apoptosis through inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP. Oncogene 2005; 24: 6877-6889. (Pubitemid 41509411)
39. Tong QS, Zheng LD, Wang L, Zeng FQ, Chen FM, Dong JH, Lu GC: Downregulation of XIAP expression induces apoptosis and enhances chemotherapeutic sensitivity in human gastric cancer cells. Cancer Gene Ther 2005; 12: 509-514. (Pubitemid 40629341)
40. Carter BZ, Mak DH, Schober WD, Koller E, Pinilla C, Vassilev LT, Reed JC, Andreeff M: Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML. Blood 2010; 115: 306-314.
41. Mohapatra S, Chu B, Zhao X, Pledger WJ: Accumulation of p53 and reductions in XIAP abundance promote the apoptosis of prostate cancer cells. Cancer Res 2005; 65: 7717-7723. (Pubitemid 41297246)
42. Vaughn AE, Deshmukh M: Essential postmitochondrial function of p53 uncovered in DNA damage-induced apoptosis in neurons. Cell Death Differ 2007; 14: 973-981. (Pubitemid 46629835)
43. Dan HC, Sun M, Kaneko S, Feldman RI, Nicosia SV, Wang HG, Tsang BK, Cheng JQ: Akt phosphorylation and stabilization of Xlinked inhibitor of apoptosis protein (XIAP). J Biol Chem 2004; 279: 5405-5412. (Pubitemid 38220563)
44. Shingu T, Yamada K, Hara N, Moritake K, Osago H, Terashima M, Uemura T, Yamasaki T, Tsuchiya M: Synergistic augmentation of antimicrotubule agent-induced cytotoxicity by a phosphoinositide 3-kinase inhibitor in human malignant glioma cells. Cancer Res 2003; 63: 4044-4047. (Pubitemid 36917925)