SCOPUS 정보 검색 플랫폼

Volumn 12, Issue 5, 2014, Pages 801-814

Design, synthesis and evaluation of novel tacrine-rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease

(6) Li, Su Yi a Jiang, Neng a Xie, Sai Sai a Wang, Kelvin D G a Wang, Xiao Bing a Kong, Ling Yi a

a CHINA PHARMACEUTICAL UNIVERSITY (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; HEPATOTOXICITY; HYBRID COMPOUNDS; INHIBITORY ACTIVITY; MOLECULAR MODELING STUDIES; MULTIFUNCTIONAL AGENTS; NANOMOLAR RANGE; POTENT INHIBITOR;

CHEMISTRY; POSITIVE IONS;

BINDING SITES;

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; ANTHRAQUINONE DERIVATIVE; CHOLINESTERASE INHIBITOR; METAL; PEPTIDE FRAGMENT; RHEIN; TACRINE;

ALZHEIMER DISEASE; ANIMAL; ARTICLE; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; KINETICS; LIVER; MOLECULAR DOCKING; MOUSE; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; SYNTHESIS;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ANTHRAQUINONES; CHEMISTRY TECHNIQUES, SYNTHETIC; CHOLINESTERASE INHIBITORS; DRUG DESIGN; KINETICS; LIVER; METALS; MICE; MOLECULAR DOCKING SIMULATION; PEPTIDE FRAGMENTS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; TACRINE;

EID: 84891877160 PISSN: 14770520 EISSN: None Source Type: Journal
DOI: 10.1039/c3ob42010h Document Type: Article

Times cited : (85)

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