Synthesis and biological activity of new 2,3-dihydro-1H-cyclopenta[b]- quinoline derivatives as acetylcholinesterase inhibitors

Letters in Drug Design and Discovery

Volumn 9, Issue 7, 2012, Pages 645-654

  Szymański, Paweł ^a   Markowicz, Magdalena ^a   Bajda, Marek ^b   Malawska, Barbara ^b   Mikiciuk Olasik, Elzbieta ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Acetylcholinesterase inhibitors; Alzheimer's disease; Cyclopenta b quinoline; Ellman method; Fluorobenzoic acid; Molecular docking

Indexed keywords

2,3 DIHYDRO 1H CYCLOPENTA[B]QUINOLINE DERIVATIVE; ACETYLCHOLINESTERASE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; N [2 (2,3 DIHYDRO 1H CYCLOPENTA[B]QUINOLIN 9 YLAMINO)ETHYL] 4 FLUOROBENZAMIDE; N [3 (2,3 DIHYDRO 1H CYCLOPENTA[B]QUINOLIN 9 YLAMINO)PROPYL] 4 FLUOROBENZAMIDE; N [4 (2,3 DIHYDRO 1H CYCLOPENTA[B]QUINOLIN 9 YLAMINO)BUTYL] 4 FLUOROBENZAMIDE; N [5 (2,3 DIHYDRO 1H CYCLOPENTA[B]QUINOLIN 9 YLAMINO)PENTYL] 4 FLUOROBENZAMIDE; N [6 (2,3 DIHYDRO 1H CYCLOPENTA[B]QUINOLIN 9 YLAMINO)HEXYL] 4 FLUOROBENZAMIDE; N [7 (2,3 DIHYDRO 1H CYCLOPENTA[B]QUINOLIN 9 YLAMINO)HEPTYL] 4 FLUOROBENZAMIDE; N [8 (2,3 DIHYDRO 1H CYCLOPENTA[B]QUINOLIN 9 YLAMINO)OCTYL] 4 FLUOROBENZAMIDE; N [9 (2,3 DIHYDRO 1H CYCLOPENTA[B]QUINOLIN 9 YLAMINO)NONYL] 4 FLUOROBENZAMIDE; TACRINE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; DRUG ACTIVITY; DRUG MECHANISM; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; MOLECULAR MODEL; PRIORITY JOURNAL; SPECTROPHOTOMETRY;

EID: 84863702839     PISSN: 15701808     EISSN: 1875628X     Source Type: Journal    
DOI: 10.2174/157018012801319454     Document Type: Article

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