Brown drug substance color investigation in cell culture manufacturing using chemically defined media: A case study

Process Biochemistry

Volumn 49, Issue 1, 2014, Pages 130-139

  Xu, Jianlin ^a   Jin, Mi ^a   Song, Hangtian ^b   Huang, Chao ^a   Xu, Xuankuo ^a   Tian, Jun ^a   Qian, Nan Xin ^a   Steger, Kirby ^b   Lewen, Nancy S ^b   Tao, Li ^b   Li, Zheng Jian ^a  

^a BRISTOL MYERS SQUIBB COMPANY   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

Chemically defined media; CHO cell culture; Iron; Kynurenine; N formylkynurenine; Protein drug substance color

Indexed keywords

CHEMICALLY DEFINED MEDIAS; CHO CELL CULTURES; KYNURENINE; N-FORMYLKYNURENINE; PROTEIN DRUGS;

AMINO ACIDS; CELL CULTURE; IRON; MANUFACTURE; PROTEINS;

COLOR;

EID: 84891834855     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2013.10.015     Document Type: Article

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