Effect of cell culture medium components on color of formulated monoclonal antibody drug substance

Biotechnology Progress

Volumn 29, Issue 5, 2013, Pages 1270-1277

  Vijayasankaran, Natarajan ^a   Varma, Sharat ^a   Yang, Yi ^a   Mun, Melissa ^a   Arevalo, Silvana ^a   Gawlitzek, Martin ^a   Swartz, Trevor ^a   Lim, Amy ^a   Li, Feng ^a   Zhang, Boyan ^a   Meier, Steve ^a   Kiss, Robert ^a  

^a GENENTECH INC   (United States)

Author keywords

Antibody; B12; B2; B6; B9; Cell culture; CHO; Fed batch; Ferrous sulfate; Iron; Medium optimization; Protein color

Indexed keywords

B12; B2; B6; B9; CHO; FED BATCHES; FERROUS SULFATE; MEDIUM OPTIMIZATION;

ANTIBODIES; BATCH CELL CULTURE; CELL CULTURE; IRON; MONOCLONAL ANTIBODIES; OPTIMIZATION;

COLOR;

CULTURE MEDIUM; CYANOCOBALAMIN; FOLIC ACID; IRON; MONOCLONAL ANTIBODY; PYRIDOXAL; PYRIDOXINE; RIBOFLAVIN; VITAMIN B COMPLEX;

ANIMAL; BIOREACTOR; CHEMISTRY; CHO CELL LINE; COLOR; CRICETULUS; CULTURE MEDIUM; CULTURE TECHNIQUE; ION EXCHANGE CHROMATOGRAPHY;

ANIMALS; ANTIBODIES, MONOCLONAL; BIOREACTORS; CELL CULTURE TECHNIQUES; CHO CELLS; CHROMATOGRAPHY, ION EXCHANGE; COLOR; CRICETULUS; CULTURE MEDIA; FOLIC ACID; IRON; PYRIDOXAL; PYRIDOXINE; RIBOFLAVIN; VITAMIN B 12; VITAMIN B COMPLEX;

EID: 84886753050     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1772     Document Type: Article

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