Characterization of the basic charge variants of a human IgG1: Effect of copper concentration in cell culture media

mAbs

Volumn 3, Issue 6, 2011, Pages 577-583

  Kaschak, Timothy ^a   Boyd, Daniel ^a   Lu, Franklin ^a   Derfus, Gayle ^a   Kluck, Brian ^a   Nogal, Bartek ^a   Emery, Craig ^a   Summers, Christie ^a   Zheng, Kai ^a   Bayer, Robert ^a   Amanullah, Ashraf ^a   Yan, Boxu ^a  

^a GENENTECH INC   (United States)

Author keywords

Antibody; Basic charge variants; Copper; Mass spectrometry; Proline amidation

Indexed keywords

COPPER ION; IMMUNOGLOBULIN G1; PROLINE; AMIDE; COPPER; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY;

AMIDATION; ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CAPILLARY ISOELECTRIC FOCUSING; CULTURE MEDIUM; HEAVY CHAIN; ION EXCHANGE CHROMATOGRAPHY; NONHUMAN; PEPTIDE MAPPING; PROTEIN VARIANT; ANIMAL; CHEMISTRY; CHO CELL; GENETICS; HAMSTER; HUMAN; ISOELECTRIC FOCUSING; METABOLISM; PROTON MOTIVE FORCE;

AMIDES; ANIMALS; ANTIBODIES, MONOCLONAL; CHO CELLS; CHROMATOGRAPHY, ION EXCHANGE; COPPER; CRICETINAE; CULTURE MEDIA; HUMANS; IMMUNOGLOBULIN G; ISOELECTRIC FOCUSING; PEPTIDE MAPPING; PROLINE; PROTON-MOTIVE FORCE;

EID: 81255210860     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.3.6.17959     Document Type: Article

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