Hydroxocobalamin association during cell culture results in pink therapeutic proteins

mAbs

Volumn 5, Issue 6, 2013, Pages 974-981

  Prentice, Kenneth M ^a   Gillespie, Ronald ^a   Lewis, Nathan ^a   Fujimori, Kiyoshi ^b   McCoy, Rebecca ^a   Bach, Julia ^a   Connell Crowley, Lisa ^a   Eakin, Catherine M ^a  

^a AMGEN INC   (United States)

^b AMGEN INC   (United States)

Author keywords

Cobalamin; Color; Monoclonal antibody; Process control; Vitamin B12

Indexed keywords

CYANOCOBALAMIN; HYBRID PROTEIN; HYDROXOCOBALAMIN; MONOCLONAL ANTIBODY; POTASSIUM CYANIDE; PROTEIN;

ARTICLE; CELL CULTURE; COLOR; CONTROLLED STUDY; HUMAN; LIGHT; PROCESS DEVELOPMENT; PRODUCT DEVELOPMENT; PROTEIN PURIFICATION; PURIFICATION; ANIMAL; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL LINE; COLORIMETRY; CRICETULUS; CULTURE TECHNIQUE; PROTEIN ENGINEERING;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL CULTURE TECHNIQUES; CHEMISTRY TECHNIQUES, ANALYTICAL; CHO CELLS; COLOR; COLORIMETRY; CRICETULUS; HYDROXOCOBALAMIN; LIGHT; MOLECULAR STRUCTURE; PROTEIN ENGINEERING; PROTEINS;

EID: 84889871265     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.25921     Document Type: Article

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