Recurrent implantation failure: Definition and management

Reproductive BioMedicine Online

Volumn 28, Issue 1, 2014, Pages 14-38

  Coughlan, C ^a   Ledger, W ^b   Wang, Q ^c   Liu, Fenghua ^d   Demirol, Aygul ^e   Gurgan, Timur ^e   Cutting, R ^a   Ong, K ^f   Sallam, H ^g   Li, T C ^a  

^a JESSOP HOSPITAL FOR WOMEN   (United Kingdom)

^b ROYAL HOSPITAL FOR WOMEN   (Australia)

^c THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^d Women and Children Hospital of Guangdong Province   (China)

^e Infertility and IVF Center   (Turkey)

^f MONASH IVF   (Australia)

^g ALEXANDRIA UNIVERSITY   (Egypt)

Author keywords

embryo; failure; fibroids; hysterosalpingogram; implantation; IVF

Indexed keywords

ACETYLSALICYLIC ACID; FOLLITROPIN; GRANULOCYTE COLONY STIMULATING FACTOR; HEPARIN; MUELLERIAN INHIBITING FACTOR; SILDENAFIL;

ALCOHOL CONSUMPTION; BLASTOCYST; BODY MASS; CHROMOSOME ABERRATION; CONGENITAL MALFORMATION; DNA FRAGMENTATION; ECHOGRAPHY; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; ENDOMETRIUM POLYP; ESTROGEN THERAPY; FERTILIZATION IN VITRO; FETUS ECHOGRAPHY; FREEZE THAWING; HATCHING; HYDROSALPINX; HYSTEROGRAPHY; HYSTEROSALPINGOGRAPHY; HYSTEROSCOPY; INFERTILITY THERAPY; INTRAMURAL FIBROID; INTRAUTERINE ADHESION; KARYOTYPING; LAPAROSCOPY; LIFESTYLE MODIFICATION; LUTEAL PHASE; MATERNAL AGE; METABOLOMICS; NIDATION; OOCYTE; OVARIAN FUNCTION TEST; OVARY FOLLICLE CELL; OVARY FUNCTION; PREGNANCY DISORDER; PREIMPLANTATION GENETIC DIAGNOSIS; RECURRENT IMPLANTATION FAILURE; REVIEW; SALPINGECTOMY; SALPINGOSTOMY; SMOKING CESSATION; SONOHYSTEROGRAPHY; SPERM; SUBMUCOUS FIBROID; THROMBOPHILIA; UTERINE CERVIX MUCUS; UTERINE TUBE; UTERUS DISEASE; UTERUS MALFORMATION; UTERUS MYOMA;

EMBRYO; FAILURE; FIBROIDS; HYSTEROSALPINGOGRAM; IMPLANTATION; IVF;

ADULT; DISEASE MANAGEMENT; EMBRYO IMPLANTATION; EMBRYO TRANSFER; FEMALE; HUMANS; HYSTEROSALPINGOGRAPHY; INFERTILITY; KARYOTYPING; MALE; OOCYTES; OVARY; PREGNANCY; PREGNANCY OUTCOME; RECURRENCE; SPERMATOZOA; TREATMENT FAILURE; UTERUS;

EID: 84891735858     PISSN: 14726483     EISSN: 14726491     Source Type: Journal    
DOI: 10.1016/j.rbmo.2013.08.011     Document Type: Review

References (291)

1. American Society Reproductive Medicine The role of assisted hatching in in vitro fertilization: a review of the literature Fertil. Steril. 90 2008
2. American Society Reproductive Medicine Obesity and reproduction: an educational bulletin Fertil. Steril. 90 2008 S21 S29
3. A.M. Abou-Setta, H.G. Al-Inany, R.T. Mansour, G.I. Serour, and M.A. Aboulghar Soft versus firm embryo transfer catheters for assisted reproduction: a systematic review and meta-analysis Hum. Reprod. 20 2005 3114 3121
4. A.M. Abou-Setta, R.T. Mansour, H.G. Al-Inany, M.M. Aboulghar, M.A. Aboulghar, and G.I. Serour Among women undergoing embryo transfer, is the probability of pregnancy and live birth improved with ultrasound guidance over clinical touch alone? A systemic review and meta-analysis of prospective randomized trials Fertil. Steril. 88 2007 333 341
5. F. Absalan, A. Ghannadi, M. Kazerooni, R. Parifar, F. Jamalzadeh, and S. Amiri Value of sperm chromatin dispersion test in couples with unexplained recurrent abortion J. Assist. Reprod. Genet. 29 2012 11 14
6. R.J. Aitken, and G.N. De Iuliis Origins and consequences of DNA damage in male germ cells Reprod. Biomed. Online 14 2007 727 733
7. B. Almog, I. Levin, I. Wagman, R. Kapustiansky, T. Schwartz, N. Mey-Raz, A. Amit, and F. Azem Interval double transfer improves treatment success in patients with repeated IVF/ET failures J. Assist. Reprod. Genet. 25 2008 353 357
8. S.M. Ascher, L.L. Arnold, R.H. Patt, J.J. Schruefer, A.S. Bagley, R.C. Semelka, R.K. Zeman, and J.A. Simon Adenomyosis: prospective comparison of MR imaging and transvaginal sonography Radiology 190 1994 803 806
9. J. Ashkenazi, R. Yoeli, R. Orvieto, J. Shalev, Z. Ben-Rafael, and I. Bar-Hava Double (consecutive) transfer of early embryos and blastocysts: aims and results Fertil. Steril. 74 2000 936 940
10. S. Assou, D. Haouzi, J. De Vos, and S. Hamamah Human cumulus cells as biomarkers for embryo and pregnancy outcomes Mol. Hum. Reprod. 16 2010 531 538
11. E. Atzori, C. Tronci, and L. Sionis Transvaginal ultrasound in the diagnosis of diffuse adenomyosis Gynecol. Obstet. Invest. 42 1996 39 41
12. G. Ayida, P. Chamberlain, D. Barlow, and S. Kennedy Uterine cavity assessment prior to in-vitro fertilization: comparison of transvaginal scanning, saline contrast hysterosonography and hysteroscopy Ultrasound Obstet. Gynecol. 10 1997 59 62
13. F. Azem, A. Many, I. Ben Ami, I. Yovel, A. Amit, J.B. Lessing, and M.J. Kupferminc Increased rates of thrombophilia in women with repeated IVF failures Hum. Reprod. 19 2004 368 370
14. E.B. Baart, E. Martini, I. van den Berg, N.S. Macklon, R.J. Galjaard, B.C. Fauser, and D. Van Opstal Preimplantation genetic screening reveals a high incidence of aneuploidy and mosaicism in embryos from young women undergoing IVF Hum. Reprod. 21 2006 223 233
15. E.B. Baart, E. Martini, M.J. Eijkemans, D. Van Opstal, N.G. Beckers, A. Verhoeff, N.S. Macklon, and B.C. Fauser Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: a randomized controlled trial Hum. Reprod. 22 2007 980 988
16. J. Balasch, E. Vidal, J. Penarrubia, R. Casamitjana, F. Carmona, M. Creus, F. Fabreques, and J.A. Vanrell Suppression of LH during ovarian stimulation: analysing threshold values and effects on ovarian response and the outcome of assisted reproduction in down-regulated women stimulated with recombinant FSH Hum. Reprod. 16 2001 1636 1643
17. H. Ban-Frangez, T. Tomazevic, I. Virant-Klun, I. Verdenik, M. Ribic-Pucelj, and E.V. Bokal The outcome of singleton pregnancies after IVF/ICSI in women before and after hysteroscopic resection of a uterine septum compared to normal controls Eur. J. Obstet. Gynecol. Reprod. Biol. 146 2009 184 187
18. I. Bar-Hava, R. Kerner, R. Yoeli, J. Ashkenazi, Y. Shalev, and R. Orvieto Immediate ambulation after embryo transfer: a prospective study Fertil. Steril. 83 2005 594 597
19. A. Barash, N. Dekel, S. Fieldust, I. Segal, E. Schechtman, and I. Granot Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilisation Fertil. Steril. 79 2003 1317 1322
20. C.L. Barratt, R.J. Aitken, L. Bjorndahl, D.T. Carrell, P. de Boer, U. Kvist, S.E. Lewis, S.D. Perreault, M.J. Perry, L. Ramos, B. Robaire, S. Ward, and A. Zini Sperm DNA: organization, protection and vulnerability: from basic science to clinical applications-a position report Hum. Reprod. 25 2010 824 838
21. B. Bartoov, A. Berkovitz, F. Eltes, A. Kogosovsky, A. Yagoda, H. Lederman, S. Artzi, M. Gross, and Y. Barak Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection Fertil. Steril. 80 2003 1413 1419
22. M. Bazot, E. Darai, J. Rouger, R. Detchev, A. Cortez, and S. Uzan Limitations of transvaginal sonography for the diagnosis of adenomyosis, with histopathological correlation Ultrasound Obstet. Gynecol. 20 2002 605 611
23. M. Benkhalifa, A. Demirol, T. Sari, E. Balashova, M. Tsouroupaki, Y. Giakoumakis, and T. Gurgan Autologous embryo-cumulus cells co-culture and blastocyst transfer in repeated implantation failures: a collaborative prospective randomized study Zygote 20 2012 173 180
24. G. Bernard, E. Darai, C. Poncelet, J.L. Benifla, and P. Madelenat Fertility after hysteroscopic myomectomy: effect of intramural myomas associated Eur. J. Obstet. Gynecol. Reprod. Biol. 88 2000 85 90
25. I. Bildirici, O. Bukulmez, A. Ensari, H. Yarali, and T. Gurgan A prospective evaluation of the effect of salpingectomy on endometrial receptivity in cases of women with communicating hydrosalpinges Hum. Reprod. 16 2001 2422 2426
26. A. Birkenfeld, T. Mukaida, L. Minichiello, M. Jackson, N.G. Kase, and M. Yemini Incidence of autoimmune antibodies in failed embryo transfer cycles Am. J. Reprod. Immunol. 31 1994 65 68
27. D. Blake, C. Farquhar, N. Johnson, and M. Proctor Cleavage stage versus blastocyst stage embryo transfer in assisted conception Cochrane Database Syst. Rev. 2007 CD002118
28. M. Bloechle What is a hydrosalpinx? A plea for the use of a proper terminology in scientific discussion Hum. Reprod. 14 1999 578
29. S.M. Blois, B.F. Klapp, and G. Barrientos Decidualisation and angiogenesis in early pregnancy: unravelling the functions of DC and NK cells J. Reprod. Immunol. 88 2011 86 92
30. A. Borini, N. Tarozzi, D. Bizzaro, M.A. Bonu, L. Fava, C. Flamigni, and G. Coticchio Sperm DNA fragmentation: paternal effect on early post-implantation embryo development in ART Hum. Reprod. 21 2006 2876 2881
31. J. Bosteels, S. Weyers, P. Puttemans, C. Panayotidis, B. Van Herendael, V. Gomel, B.W. Mol, C. Mathieu, and T. D'Hooghe The effectiveness of hysteroscopy in improving pregnancy rates in subfertile women without other gynaecological symptoms: a systematic review Hum. Reprod. Update 16 2010 1 11
32. S. Brahem, M. Mehdi, H. Landolsi, S. Mougou, H. Elghezal, and A. Saad Semen parameters and sperm DNA fragmentation as causes of recurrent pregnancy loss Urology 78 2011 792 796
33. D.R. Brison, F. Houghton, D. Falconer, S.A. Roberts, J. Hawkhead, P.G. Humpherson, B.A. Lieberman, and H.J. Leese Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover Hum. Reprod. 19 2004 2319 2324
34. B. Bromley, T. Shipp, and B. Benacerraf Adenomyosis: sonographic findings and diagnostic accuracy J. Ultrasound Med. 19 2000 529 534
35. J. Brown, K. Buckingham, A.M. Abou-Setta, and W. Buckett Ultrasound versus 'clinical touch' for catheter guidance during embryo transfer in women Cochrane Database Syst. Rev. 20 2010 CD006107
36. M. Bungum, P. Humaidan, M. Spano, K. Jepson, L. Bungum, and A. Giwercman The predictive value of sperm chromatin structure assay (SCSA) parameters for the outcome of intrauterine insemination, IVF and ICSI Hum. Reprod. 19 2004 1401 1408
37. M. Bungum, P. Humaidan, A. Axmon, M. Spano, L. Bungum, J. Erenpreiss, and A. Giwercman Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome Hum. Reprod. 22 2007 174 179
38. V.C. Buttram Jr., and R. Reiter Uterine leiomyomata: etiology, symptomatology, and management Fertil. Steril. 36 1981 433 445
39. M. Campana, A. Serra, and G. Neri Role of chromosome aberrations in recurrent abortion: a study of 269 balanced translocations Am. J. Med. Genet. 24 1986 341 356
40. E. Camus, C. Poncelet, F. Goffinet, B. Wainer, F. Merlet, I. Nisand, and H.J. Philippe Pregnancy rates after in-vitro fertilization in cases of tubal infertility with and without hydrosalpinx: a meta-analysis of published comparative studies Hum. Reprod. 14 1999 1243 1249
41. M. Canis, G. Mage, J.L. Pouly, H. Manhes, A. Wattiez, and M.A. Bruhat Laparoscopic distal tuboplasty: report of 87 cases and a 4-year experience Fertil. Steril. 56 1991 616 621
42. D.A. Clark, and R.B. Stricker Is intravenous immunoglobulins (IVIG) efficacious in early pregnancy failure? A critical review and meta-analysis for patients who fail in vitro fertilisation and embryo transfer (IVF) J. Assist. Reprod. Genet. 23 2006 113
43. J. Cohen, D. Wellis, and S. Munné Removal of 2 cells from cleavage stage embryos is likely to reduce the efficacy of chromosomal tests that are used to enhance implantation rates Fertil. Steril. 87 2007 496 503
44. J. Collins Mild stimulation for in vitro fertilization: making progress downward Hum. Reprod. Update 15 2009 1 3
45. J.A. Collins, K. Barnhart, and P.N. Schlegel Do sperm DNA integrity tests predict pregnancy with in vitro fertilization? Fertil. Steril. 89 2008 823 831
46. J. Conaghan, K. Hardy, A.H. Handyside, R.M. Winston, and H.J. Leese Selection criteria for human embryo transfer: a comparison of pyruvate uptake and morphology J. Assist. Reprod. Genet. 10 1993 21 30
47. G.S. Cooper, D. Baird, B.S. Hulka, C.R. Weinberg, D.A. Savitz, and C.L. Hughes Jr. Follicle-stimulating hormone concentrations in relation to active and passive smoking Obstet. Gynecol. 85 1995 407 411
48. Coughlan, C., Yuan, Xi, Demirol, A., Ledger, W., Li, T.C. Factors affecting the outcome of 'Endometrial Scratch' in women with recurrent implantation failure. J. Reprod. Med., in press.
49. C. Coulam, B. Kaider, A.S. Kaider, P. Janowicz, and R.G. Roussev Antiphospholipid antibodies associated with implantation failure after IVF.ET J. Assist. Reprod. Genet. 14 1997 603 606
50. Crosignani, and Rubin Genetic Control of Gamete Production and Function 1982 Academic Press New York
51. J.R. Cruz, A.K. Dubey, J. Patel, D. Peak, B. Hartog, and P.R. Gindoff Is blastocyst transfer useful as an alternative treatment for patients with multiple in vitro fertilization failures? Fertil. Steril. 72 1999 218 220
52. R. Cutting, D. Morroll, S.A. Roberts, S. Pickering, and A. Rutherford Elective single embryo transfer: guidelines for practice British Fertility Society and Association of Clinical Embryologists Hum. Fertil. (Camb.) 11 2008 131 146
53. G.S. Daftary, and H.S. Taylor Implantation in the human: the role of HOX genes Semin. Reprod. Med. 18 2000 311 320
54. M. Das, and H.E. Holzer Recurrent implantation failure: gamete and embryo factors Fertil. Steril. 97 2012 1021 1027
55. S. Das, D. Blake, C. Farquhar, and M.M. Seif Assisted hatching on assisted conception (IVF and ICSI) Cochrane Database Syst. Rev. 2009 CD001894
56. A. Dawood, A. Al-Talib, and T. Tulandi Predisposing factors and treatment outcome of different stages of intrauterine adhesions J. Obstet. Gynaecol. Can. 32 2010 767 770
57. A. Demirol, and T. Gurgan Effect of treatment of intrauterine pathologies with office hysteroscopy in patients with recurrent IVF failure Reprod. Biomed. Online 2004 590 594
58. A. Demirol, and T. Gurgan Effect of treatment of intrauterine pathologies with office hysteroscopy in patients with recurrent IVF failure Reprod. Biomed. Online 8 2004 590 594
59. P. Devroey, H. Godoy, J. Smitz, M. Camus, H. Tournaye, M.P. Derde, and A. Van Steirteghem Female age predicts embryonic implantation after ICSI: a case-controlled study Hum. Reprod. 11 1996 1324 1327
60. K. Dirckx, P. Cabri, A. Merien, L. Galajdova, J. Gerris, M. Dhont, and P. De Sutter Does low-dose aspirin improve pregnancy rate in IVF/ICSI? A randomized double-blind placebo controlled trial Hum. Reprod. 24 2009 856 860
61. J. Donnez, and P. Jadoul What are the implications of myomas on fertility? A need for a debate? Hum. Reprod. 17 2002 1424 1430
62. P. Donoso, C. Staessen, B.C. Fauser, and P. Devroey Current value of preimplantation genetic aneuploidy screening in IVF Hum. Reprod. Update 13 2007 15 25
63. H. Du, and H.S. Taylor Molecular regulation of Müllerian development by Hox genes Ann. N. Y. Acad. Sci. 1034 2004 152 165
64. J.B. Dubuisson, C. Chapron, P. Morice, F.X. Aubriot, H. Foulot, and J. Bouquet de Joliniere Laparoscopic salpingostomy: fertility results according to the tubal mucosal appearance Hum. Reprod. 9 1994 334 339
65. E.H. Duran, M. Morshedi, S. Taylor, and S. Oehninger Sperm DNA quality predicts intrauterine insemination outcome: a prospective cohort study Hum. Reprod. 17 2002 3122 3128
66. E. Edi-Osagie, L. Hooper, and M.W. Seif The impact of assisted hatching on live birth rates and outcomes of assisted conception: a systematic review Hum. Reprod. 18 2003 1828 1835
67. P.E. Egbase, M. al-Sharhan, S. al-Othman, M. al-Mutawa, E.E. Udo, and J.G. Grudzinskas Incidence of microbial growth from the tip of the embryo transfer catheter after embryo transfer in relation to clinical pregnancy rate following in-vitro fertilization and embryo transfer Hum. Reprod. 11 1996 1687 1689
68. T. Eldar-Geva, S. Meagher, D.L. Healy, V. MacLachlan, S. Breheny, and C. Wood Effect of intramural, subserosal, and submucosal uterine fibroids on the outcome of assisted reproductive technology treatment Fertil. Steril. 70 1998 687 691
69. T. El-Toukhy, S. Sunkara, and Y. Khalaf Local endometrial injury and IVF outcome: a systematic review and meta-analysis Reprod. Biomed. Online. 25 2012 345 354
70. J. Erenpreiss, S. Hlevicka, J. Zalkalns, and J. Erenpreisa Effect of leukocytospermia on sperm DNA integrity: a negative effect in abnormal semen samples J. Androl. 23 2002 717 723
71. J. Erenpreiss, M. Bungum, M. Spano, S. Elzanaty, J. Orbidans, and A. Giwercman Intra-individual variation in sperm chromatin structure assay parameters in men from infertile couples: clinical implications Hum. Reprod. 21 2006 2061 2064
72. D.P. Evenson Flow cytometric analysis of male germ cell quality Methods Cell Biol. 33 1990 401 410
73. D.P. Evenson, K.L. Larson, and L.K. Jost Sperm chromatin structure assay: its clinical use for detecting sperm DNA fragmentation in male infertility and comparisons with other techniques J. Androl. 23 2002 25 43
74. D.P. Evenson, and R. Wixon Data analysis of two in vivo fertility studies using Sperm Chromatin Structure Assay-derived DNA fragmentation index vs. pregnancy outcome Fertil. Steril. 90 2008 1229 1231
75. J. Farhi, J. Ashkenazi, D. Feldberg, D. Dicker, R. Orvieto, and Z. Ben Rafael Effect of uterine leiomyomata on the results of in-vitro fertilization treatment Hum. Reprod. 10 1995 2576 2578
76. L. Fedele, S. Bianchi, M. Dorta, L. Arcaini, F. Zanotti, and S. Carinelli Transvaginal ultrasonography in the diagnosis of diffuse adenomyosis Fertil. Steril. 58 1992 94 97
77. L. Fedele, L. Arcaini, F. Parazzini, P. Vercellini, and G. Di Nola Reproductive prognosis after hysteroscopic metroplasty in 102 women: life-table analysis Fertil. Steril. 59 1993 768 772
78. L. Fedele, S. Bianchi, B. Agnoli, L. Tozzi, and M. Vignali Urinary tract anomalies associated with unicornuate uterus J. Urol. 155 1996 847 848
79. W. Feichtinger, K. Papalambrou, M. Poehl, U. Krischker, and K. Neumann Smoking and in vitro fertilization: a meta-analysis J. Assist. Reprod. Genet. 14 1997 596 599
80. J.L. Fernandez, F. Vazquez-Gundin, A. Delgado, V.J. Goyanes, J. Ramiro-Diaz, J. de la Torre, and J. Gosalvez DNA breakage detection-FISH (DBD-FISH) in human spermatozoa: technical variants evidence different structural features Mutat. Res. 453 2000 77 82
81. H. Fernandez, O. Sefrioui, C. Virelizier, A. Gervaise, V. Gomel, and R. Frydman Hysteroscopic resection of submucosal myomas in patients with infertility Hum. Reprod. 16 2001 1489 1492
82. J.L. Fernandez, L. Muriel, M.T. Rivero, V. Goyanes, R. Vazquez, and J.G. Alvarez The sperm chromatin dispersion test: a simple method for the determination of sperm DNA fragmentation J. Androl. 24 2003 59 66
83. R. Fernandez-Gonzalez, P.N. Moreira, M. Perez-Crespo, M. Sanchez-Martin, M.A. Ramirez, E. Pericuesta, A. Bilbao, P. Bermejo-Alvarez, J. de Dios Hourcade, F.R. de Fonseca, and A. Gutierrez-Adan Long-term effects of mouse intracytoplasmic sperm injection with DNA-fragmented sperm on health and behavior of adult offspring Biol. Reprod. 78 2008 761 772
84. A.P. Ferraretti, A. La Marca, B.C. Fauser, B. Tarlatzis, G. Nargund, and L. Gianaroli ESHRE consensus on the definition of 'poor response' to ovarian stimulation for in vitro fertilization: the Bologna criteria Hum. Reprod. 26 2011 1616 1624
85. M.R. Fluker, C.G. Zouves, and M.W. Bebbington A prospective randomized comparison of zygote intrafallopian transfer and in vitro fertilisation-embryo transfer for nontubal factor infertility Fertil. Steril. 60 1993 519
86. E. Fragouli, M. Lenzi, R. Ross, M. Katz-Jaffe, W.R. Schoolcraft, and D. Wells Comprehensive molecular cytogenetic analysis of the human blastocyst stage Hum. Reprod. 2008 2008 2596 2608
87. E. Fragouli, M. Katz-Jaffe, S. Alfarawati, J. Stevens, P. Colls, N. Goodall, S. Tormasi, C. Gutierrez-Mateo, R. Prates, W.B. Schoolcraft, S. Munné, and D. Wells Comprehensive chromosome screening of polar bodies and blastocysts from couples experiencing repeated implantation failure Fertil. Steril. 94 2010 875 887
88. E. Fragouli, S. Alfarawati, D. Daphnis, N. Goodall, A. Mania, T. Griffiths, A. Gordon, and D. Wells Cytogenetic analysis of human blastocysts with the use of FISH, CGH and aCGH: scientific data and technical evaluation Hum. Reprod. 26 2011 480 490
89. D.I. Galen, N. Khan, and K.S. Richter Essure multicentre off-label treatment for hydrosalpinx before in vitro fertilization J. Minim. Invasive Gynecol. 18 2011 338 342
90. L. Gandini, F. Lombardo, D. Paoli, F. Caruso, P. Eleuteri, G. Leter, R. Ciriminna, F. Culasso, F. Dondero, A. Lenzi, and M. Spano Full-term pregnancies achieved with ICSI despite high levels of sperm chromatin damage Hum. Reprod. 19 2004 1409 1417
91. C.R. Garcia, and R.W. Tureck Submucosal leiomyomas and infertility Fertil. Steril. 42 1984 16 19
92. D.K. Gardner, M. Lane, J. Stevens, T. Schlenker, and W.B. Schoolcraft Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer Fertil. Steril. 73 2000 1155 1158
93. D.K. Gardner, M. Lane, J. Stevens, and W.B. Schoolcraft Noninvasive assessment of human embryo nutrient consumption as a measure of developmental potential Fertil. Steril. 76 2001 1175 1180
94. D.K. Gardner, E. Surrey, D. Minjarez, A. Leitz, J. Stevens, and W.B. Schoolcraft Single blastocyst transfer: a prospective randomized trial Fertil. Steril. 81 2004 551 555
95. T.A. Gelbaya, M. Kyrgiou, T.C. Li, C. Stern, and L.G. Nardo Low-dose aspirin for in vitro fertilization: a systematic review and meta-analysis Hum. Reprod. Update 13 2007 357 364
96. B. Gellersen, I.A. Brosens, and J.J. Brosens Decidualisation of the human endometrium: mechanisms, functions and clinical perspectives Semin. Reprod. Med. 25 2007 445 453
97. T.S. Ghobara, D.J. Cahill, W.C. Ford, H.M. Collyer, P.E. Wilson, L. Al-Nuaim, and J.M. Jenkins Effects of assisted hatching method and age on implantation rates of IVF and ICSI Reprod. Biomed. Online 13 2006 261 267
98. L. Gianaroli, M.C. Magli, A.P. Ferraretti, and S. Munné Preimplantation diagnosis for aneuploidies in patients undergoing in vitro fertilization with a poor prognosis: identification of the categories for which it should be proposed Fertil. Steril. 72 1999 837 844
99. L. Gianaroli, S. Gordts, A. D'Angelo, M.C. Magli, I. Brosens, C. Cetera, R. Campo, and A.P. Ferraretti Effect of inner myometrium fibroid on reproductive outcome after IVF Reprod. Biomed. Online 10 2005 473 477
100. K.B. Glass, C. Green, M.R. Fluker, W.B. Schoolcraft, R.T. McNamee, and D.R. Meldrum Multicenter randomized controlled trial of cervical irrigation at the time of embryo transfer Fertil. Steril. 73 Suppl. 1 2000 S31
101. N. Gleicher, A. Vidali, and D.H. Barad Successful treatment of unresponsive thin endometrium Fertil. Steril. 95 2011 e2113 e2127
102. M. Goldenberg, E. Sivan, Z. Sharabi, D. Bider, J. Rabinovici, and D.S. Seidman Outcome of hysteroscopic resection of submucous myomas for infertility Fertil. Steril. 64 1995 714 716
103. V. Goossens, M. De Rycke, A. De Vos, C. Staessen, A. Michiels, W. Verpoest, A. Van Steirteghem, C. Bertrand, I. Liebaers, P. Devroey, and K. Sermon Diagnostic efficiency, embryonic development and clinical outcome after the biopsy of one or two blastomeres for preimplantation genetic diagnosis Hum. Reprod. 23 2008 481 492
104. W. Gorczyca, F. Traganos, H. Jesionowska, and Z. Darzynkiewicz Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells: analogy to apoptosis of somatic cells Exp. Cell Res. 207 1993 202 205
105. S. Goto, K. Takebayashi, M. Shiotani, M. Fujiwara, M. Hirose, and Y. Noda Effectiveness of 2-step (consecutive) embryo transfer. Comparison with cleavage-stage transfer J. Reprod. Med. 48 2003 370 374
106. A.L. Gott, K. Hardy, R.M. Winston, and H.J. Leese Non-invasive measurement of pyruvate and glucose uptake and lactate production by single human preimplantation embryos Hum. Reprod. 5 1990 104 108
107. E. Grandone, D. Colaizzo, A. Lo Bue, M.G. Checola, E. Cittadini, and M. Margaglione Inherited thrombophilia and in vitro fertilization implantation failure Fertil. Steril. 76 2001 201 202
108. E. Greco, M. Iacobelli, L. Rienzi, F. Ubaldi, S. Ferrero, and J. Tesarik Reduction of the incidence of sperm DNA fragmentation by oral antioxidant treatment J. Androl. 26 2005 349 353
109. E. Greco, F. Scarselli, M. Iacobelli, L. Rienzi, F. Ubaldi, S. Ferrero, G. Franco, N. Anniballo, C. Mendoza, and J. Tesarik Efficient treatment of infertility due to sperm DNA damage by ICSI with testicular spermatozoa Hum. Reprod. 20 2005 226 230
110. G.F. Grimbizis, M. Camus, B.C. Tarlatzis, J.N. Bontis, and P. Devroey Clinical implications of uterine malformations and hysteroscopic treatment results Hum. Reprod. Update 7 2001 161 174
111. G.F. Grimbizis, D. Tsolakidis, T. Mikos, E. Anagnostou, E. Asimakopoulos, P. Stamatopoulos, and B.C. Tarlatzis A prospective comparison of transvaginal ultrasound, saline infusion sonohysterography, and diagnostic hysteroscopy in the evaluation of endometrial pathology Fertil. Steril. 94 2010 2720 2725
112. F. Guerif, R. Bidault, O. Gasnier, M.L. Couet, O. Gervereau, J. Lansac, and D. Royere Efficacy of blastocyst transfer after implantation failure Reprod. Biomed. Online 9 2004 630 636
113. A. Habana, and S.F. Palter Is tubal embryo transfer of any value? A meta analysis and comparison with the society for assisted reproductive technology database Fertil. Steril. 76 2001 293
114. N. Hammadieh, A. Coomarasamy, B. Ola, S. Papaioannou, M. Afnan, and K. Sharif Ultrasound-guided hydrosalpinx aspiration during oocyte collection improves pregnancy outcome in IVF: a randomized controlled trial Hum. Reprod. 23 2008 1113 1117
115. K. Hardy, M.A. Hooper, A.H. Handyside, A.J. Rutherford, R.M. Winston, and H.J. Leese Non-invasive measurement of glucose and pyruvate uptake by individual human oocytes and preimplantation embryos Hum. Reprod. 4 1989 188 191
116. J.C. Harper, E. Coonen, A.H. Handyside, R.M. Winston, A.H. Hopman, and J.D. Delhanty Mosaicism of autosomes and sex chromosomes in morphologically normal, monospermic preimplantation human embryos Prenat. Diagn. 15 1995 41 49
117. R. Hart, Y. Khalaf, C.T. Yeong, P. Seed, A. Taylor, and P. Braude A prospective controlled study of the effect of intramural uterine fibroids on the outcome of assisted conception Hum. Reprod. 16 2001 2411 2417
118. I. Hernandez-Gonzalez, I. Gonzalez-Robayna, M. Shimada, C.M. Wayne, S.A. Ochsner, L. White, and J.S. Richards Gene expression profiles of cumulus cell oocyte complexes during ovulation reveal cumulus cells express neuronal and immune-related genes: does this expand their role in the ovulation process? Mol. Endocrinol. 20 2006 1300 1321
119. A. Hershlag, T. Paine, G.W. Cooper, G.M. Scholl, K. Rawlinson, and G. Kvapil Monozygotic twinning associated with mechanical assisted hatching Fertil. Steril. 71 1999 144 146
120. J.A. Hill, and R.T. Scott Immunologic tests and IVF: 'Please, enough already' Fertil. Steril. 74 2000 439 442
121. H.A. Homer, T.C. Li, and I.D. Cooke The septate uterus: a review of management and reproductive outcome Fertil. Steril. 73 2000 1 14
122. G. Horne, J.D. Critchlow, M.C. Newman, L. Edozien, P.L. Matson, and B.A. Lieberman A prospective evaluation of cryopreservation strategies in a two-embryo transfer programme Hum. Reprod. 12 1997 542 547
123. M.D. Hornstein, O.K. Davis, J.B. Massey, R.J. Paulson, and J.A. Collins Antiphospholipid antibodies and in vitro fertilization success: a meta-analysis Fertil. Steril. 73 2000 330 333
124. F.D. Houghton, J.A. Hawkhead, P.G. Humpherson, J.E. Hogg, A.H. Balen, A.J. Rutherford, and H.J. Leese Non-invasive amino acid turnover predicts human embryo developmental capacity Hum. Reprod. 17 2002 999 1005
125. E.G. Hughes, and B.G. Brennan Does cigarette smoking impair natural or assisted fecundity? Fertil. Steril. 66 1996 679 689
126. C.M. Hughes, S.E. Lewis, V.J. McKelvey-Martin, and W. Thompson A comparison of baseline and induced DNA damage in human spermatozoa from fertile and infertile men, using a modified comet assay Mol. Hum. Reprod. 2 1996 613 619
127. J.E. Hunt, and E.E. Wallach Uterine factors in infertility-an overview Clin. Obstet. Gynecol. 17 1974 44 64
128. A.M. Isidori, C. Pozza, D. Ganfrilli, and A. Isidori Medical treatment to improve sperm quality Reprod. Biomed. Online 12 2006 704 714
129. A. Jakab, D. Sakkas, E. Delpiano, S. Cayli, E. Kovanci, D. Ward, A. Revelli, and G. Huszar Intracytoplasmic sperm injection: a novel selection method for sperm with normal frequency of chromosomal aneuploidies Fertil. Steril. 84 2005 1665 1673
130. R. Jansen Endocrine response in the fallopian tube Endocr. Rev. 5 1984 551
131. N. Johnson, S. van Voorst, M.C. Sowter, A. Strandell, and B.W. Mol Surgical treatment for tubal disease in women due to undergo in vitro fertilisation Cochrane Database Syst Rev. 20 2010 CD002125
132. B.D. Kaider, D.E. Price, R.G. Roussev, and C.B. Coulam Antiphospholipid antibody prevalence in patients with IVF failure Am. J. Reprod. Immunol. 35 1996 388 393
133. M.A. Karimzade, H. Oskouian, S. Ahmadi, and L. Oskouian Local injury to the endometrium on the day of oocyte retrieval has a negative impact on implantation in assisted reproductive cycles: a randomized controlled trial Arch. Gynecol. Obstet. 281 2010 499 503
134. M.A. Karimzadeh, M. Ayazi Rozbahani, and N. Tabibnejad Endometrial local injury improves the pregnancy rate among recurrent implantation failure patients undergoing in vitro fertilisation/intra cytoplasmic sperm injection: a randomised clinical trial Aust. N. Z. J. Obstet. Gynaecol. 49 2009 677 680
135. Z. Katz, A. Ben-Arie, S. Lurie, M. Manor, and V. Insler Reproductive outcome following hysteroscopic adhesiolysis in Asherman's syndrome Int. J. Fertil. Menopausal Stud. 41 1996 462 465
136. P.C. Klatsky, D.E. Lane, I.P. Ryan, and V.Y. Fujimoto The effect of fibroids without cavity involvement on ART outcomes independent of ovarian age Hum. Reprod. 22 2007 521 526
137. H. Klonoff-Cohen, L. Natarajan, R. Marrs, and B. Yee Effects of female and male smoking on success rates of IVF and gamete intra-Fallopian transfer Hum. Reprod. 16 2001 1382 1390
138. A. Kontoravdis, E. Makrakis, K. Pantos, D. Botsis, E. Deligeoroglou, and G. Creatsas Proximal tubal occlusion and salpingectomy result in similar improvement in in vitro fertilization outcome in patients with hydrosalpinx Fertil. Steril. 86 2006 1642 1649
139. Y. Koot, G. Teklenburg, M. Salker, J. Brosens, and N. Macklon Molecular aspects of implantation failure Biochim. Biophys. Acta 1822 2012 1943 1950
140. A. Kowalik, M. Vichnin, H.C. Liu, W. Branch, and A.S. Berkeley Midfollicular anticardiolipin and antiphosphatidylserine antibody titers do not correlate with in vitro fertilization outcome Fertil. Steril. 68 1997 298 304
141. K.L. Larson, C.J. DeJonge, A.M. Barnes, L.K. Jost, and D.P. Evenson Sperm chromatin structure assay parameters as predictors of failed pregnancy following assisted reproductive techniques Hum. Reprod. 15 2000 1717 1722
142. K.L. Larson-Cook, J.D. Brannian, K.A. Hansen, K.M. Kasperson, E.T. Aamold, and D.P. Evenson Relationship between the outcomes of assisted reproductive techniques and sperm DNA fragmentation as measured by the sperm chromatin structure assay Fertil. Steril. 80 2003 895 902
143. N. Laufer, and A. Simon Recurrent implantation failure: current update and clinical approach to an ongoing challenge Fertil. Steril. 97 2012 1019 1020
144. N. Lavergne, J. Aristizabal, V. Zarka, R. Erny, and B. Hedon Uterine anomalies and in vitro fertilization: what are the results? Eur. J. Obstet. Gynecol. Reprod. Biol. 68 1996 29 34
145. P. Lesny, S.R. Killick, J. Robinson, G. Raven, and S.D. Maguiness Junctional zone contractions and embryo transfer: is it safe to use a tenaculum? Hum. Reprod. 14 1999 2367 2370
146. G. Letterie, L. Marshall, and M. Angle Intrauterine reflux of media during cervical irrigation at embryo transfer Fertil. Steril. 79 2003 1444 1445
147. E. Levitas, E. Lunenfeld, I. Har-Vardi, S. Albotiano, Y. Sonin, R. Hackmon-Ram, and G. Potashnik Blastocyst-stage embryo transfer in patients who failed to conceive in three or more day 2-3 embryo transfer cycles: a prospective, randomized study Fertil. Steril. 81 2004 567 571
148. D. Levran, S. Mashiach, J. Dor, J. Levron, and J. Farhi Zygote intrafallopian transfer may imnprove pregnancy rate in patients with repeated failure of implantation Fertil. Steril. 69 1998 30
149. D. Levran, J. Farhi, H. Nahum, M. Royburt, M. Glezerman, and A. Weissman Prospective evaluation of blastocyst stage transfer vs. zygote intrafallopian tube transfer in patients with repeated implantation failure Fertil. Steril. 77 2002 971 977
150. S.A. Liatsikos, G.F. Grimbizis, I. Georgiou, N. Papadopoulos, L. Lazaros, J.N. Bontis, and B.C. Tarlatzis HOX A10 and HOX A11 mutation scan in congenital malformations of the female genital tract Reprod. Biomed. Online 21 2010 126 132
151. B.A. Lieberman, S.A. Troup, and P.L. Matson Cryopreservation of embryos and pregnancy rates after IVF Lancet 340 1992 116
152. A.S. Lopes, T. Greve, and H. Callesen Quantification of embryo quality by respirometry Theriogenology 67 2007 21 31
153. D. Loutradis, P. Drakakis, K. Dallianidis, S.R. Bletsa, S. Milingos, N. Doumplis, N. Sofikitis, A. Asteriou-Dionyssiou, L. Michalas, and S. Michalas A double embryo transfer on days 2 and 4 or 5 improves pregnancy outcome in patients with good embryos but repeated failures in IVF or ICSI Clin. Exp. Obstet. Gynecol. 31 2004 63 66
154. R. Machtinger, J. Dor, M. Margolin, J. Levron, M. Baum, B. Ferber, A. Shulman, D. Bider, and D.S. Seidman Sequential transfer of day 3 embryos and blastocysts after previous IVF failures despite adequate ovarian response Reprod. Biomed. Online 13 2006 376 379
155. A. Maheshwari, S. Gurunath, F. Fatima, and S. Bhattacharya Adenomyosis and subfertility: a systematic review of prevalence, diagnosis, treatment and fertility outcomes Hum. Reprod. Update 18 2012 374 392
156. L. Mains, and B.J. Van Voorhis Optimizing the technique of embryo transfer Fertil. Steril. 94 2010 785 790
157. E. Makrakis, and K. Pantos The outcomes of hysteroscopy in women with implantation failures after in-vitro fertilization: findings and effect on subsequent pregnancy rates Curr. Opin. Obstet. Gynecol. 22 2010 339 343
158. A. Makrigiannakis, G. Petsas, B. Toth, K. Relakis, and U. Jeschke Recent advances in understanding immunology of reproductive failure J. Reprod. Immunol. 90 2011 96 104
159. G.C. Manicardi, P.G. Bianchi, S. Pantano, P. Azzoni, D. Bizzaro, U. Bianchi, and D. Sakkas Presence of endogenous nicks in DNA of ejaculated human spermatozoa and its relationship to chromomycin A3 accessibility Biol. Reprod. 52 1995 864 867
160. R.T. Mansour, C.A. Rhodes, M.A. Aboulghar, G.I. Serour, and A. Kamal Transfer of zona-free embryos improves outcome in poor prognosis patients: a prospective randomized controlled study Hum. Reprod. 15 2000 1061 1064
161. P. Marceau, D. Kaufman, S. Biron, F.S. Hould, S. Lebel, S. Marceau, and J.G. Kral Outcome of pregnancies after biliopancreatic diversion Obes. Surg. 14 2004 318 324
162. C.M. March Management of Asherman's syndrome Reprod. Biomed. Online 23 2011 63 76
163. D. Marek, M. Langley, D.K. Gardner, N. Confer, K.M. Doody, and K.J. Doody Introduction of blastocyst culture and transfer for all patients in an in vitro fertilization program Fertil. Steril. 72 1999 1035 1040
164. E.J. Margalioth, A. Ben-Chetrit, M. Gal, and T. Eldar-Geva Investigation and treatment of repeated implantation failure following IVF-ET Hum. Reprod. 21 2006 3036 3043
165. R. Marrs, D. Meldrum, S. Muasher, W. Schoolcraft, L. Werlin, and E. Kelly Randomized trial to compare the effect of recombinant human FSH (follitropin alfa) with or without recombinant human LH in women undergoing assisted reproduction treatment Reprod. Biomed. Online 8 2004 175 182
166. I. Martinelli, E. Taioli, G. Ragni, P. Levi-Setti, S.M. Passamonti, T. Battaglioli, C. Lodigiani, and P.M. Mannucci Embryo implantation after assisted reproductive procedures and maternal thrombophilia Haematologica 88 2003 789 793
167. W.P. Martins, I.A. Rocha, R.A. Ferriani, and C.O. Nastri Assisted hatching of human embryos: a systematic review and meta-analysis of randomized controlled trials Hum. Reprod. Update 17 2011 438 453
168. P.F. McComb, and A. Paleologou The intussusception salpingostomy technique for the therapy of distal oviductal occlusion at laparoscopy Obstet. Gynecol. 78 1991 443 447
169. M. McIlveen, and T.C. Li Myomectomy: a review of surgical technique Hum. Fertil. (Camb.) 8 2005 27 33
170. P. McNamee, T. Huang, A. Carwile, B. Chun, T. Kosasa, C. Morton, and F. Terada Significant increase in pregnancy rate achieved by vigorous irrigation of endocervical mucus prior to embryo transfer with the Wallace catheter in an IVF-ET program Fertil. Steril. 68 Suppl. 1 1997 S208 S209
171. L. Mettler, S. Irani, A. Kapamadzija, and K. Semm Pelviscopic tubal surgery: the acceptable vogue Hum. Reprod. 5 1990 971 974
172. M. Metwally, C.M. Farquhar, and T.C. Li Is another meta-analysis on the effects of intramural fibroids on reproductive outcomes needed? Reprod. Biomed. Online 23 2011 2 14
173. V. Mijatovic, S. Veersema, Mh. Emanuel, R. Schats, and P.G. Hompes Essure hysteroscopic tubal occlusion device for the treatment of hydrosalpinx prior to in-vitro fertilization-embryo transfer in patients with a contraindication for laparoscopy Fertil. Steril. 93 2010 1338 1342
174. V. Mijatovic, K. Dreyer, M.H. Emanuel, R. Schats, and P.G. Hompes Essure hydrosalpinx occlusion prior to IVF-ET as an alternative to laparoscopic salpingectomy Eur. J. Obstet. Gynecol. Reprod. Biol. 161 2012 42 45
175. I.D. Morris Sperm DNA damage and cancer treatment Int. J. Androl. 25 2002 255 261
176. P.M. Motta, S.A. Nottola, G. Familiari, G. Macchiarelli, E. Vizza, and S. Correr Ultrastructure of human reproduction from folliculogenesis to early embryo development. A review Ital. J. Anat. Embryol. 100 1995 9 72
177. P.M. Motta, S.A. Nottola, J. Pereda, H.B. Croxatto, and G. Familiari Ultrastructure of human cumulus oophorus: a transmission electron microscopic study on oviductal oocytes and fertilized eggs Hum. Reprod. 10 1995 2361 2367
178. R.A. Mukherjee, S. Hollins, M.T. Abou-Saleh, and J. Turk Low level alcohol consumption and the fetus BMJ 330 2005 375 376
179. S. Munné, C. Magli, A. Adler, G. Wright, K. de Boer, D. Mortimer, M. Tucker, J. Cohen, and L. Gianaroli Treatment-related chromosome abnormalities in human embryos Hum. Reprod. 12 1997 780 784
180. L. Muriel, M. Meseguer, J.L. Fernandez, J. Alvarez, J. Remohi, A. Pellicer, and N. Garrido Value of the sperm chromatin dispersion test in predicting pregnancy outcome in intrauterine insemination: a blind prospective study Hum. Reprod. 21 2006 738 744
181. R. Narayan, and Rajat K. Goswamy Treatment of submucous fibroids, and outcome of assisted conception J. Am. Assoc. Gynecol. Laparosc. 1 1994 307 311
182. S.A. Narvekar, N. Gupta, N. Shetty, A. Kottur, M. Srinivas, and K.A. Rao Does local endometrial injury in the nontransfer cycle improve the IVF-ET outcome in the subsequent cycle in patients with previous unsuccessful IVF? A randomized controlled pilot study J. Hum. Reprod. Sci. 3 2010 15 19
183. National Institute for Health and Care Excellence, 2013. Fertility: assessment and treatment for people with fertility problems. Clinical Guidelines CG156.
184. H.C.o.t. Netherlands Preconception Care: A Good Beginning 2007 Health Council of the Netherlands The Hague
185. L.E. Northrop, N.R. Treff, B. Levy, and R.T. Scott Jr. SNP microarray-based 24 chromosome aneuploidy screening demonstrates that cleavage stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts Mol. Hum. Reprod. 16 2010 590 600
186. S.A. Nottola, G. Familiari, G. Micara, C. Aragona, and P.M. Motta The ultrastructure of human cumulus-corona cells at the time of fertilization and early embryogenesis. A scanning and transmission electron microscopic study in an in vitro fertilization program Arch. Histol. Cytol. 54 1991 145 161
187. F.G. Oliveira, V.G. Abdelmassih, M.P. Diamond, D. Dozortsev, N.R. Melo, and R. Abdelmassih Impact of subserosal and intramural uterine fibroids that do not distort the endometrial cavity on the outcome of in vitro fertilization-intracytoplasmic sperm injection Fertil. Steril. 81 2004 582 587
188. J.B. Oliveira, M. Cavagna, C.G. Petersen, A.L. Mauri, F.C. Massaro, L.F. Silva, R.L. Baruffi, and J.G. Franco Jr. Pregnancy outcomes in women with repeated implantation failures after intracytoplasmic morphologically selected sperm injection (IMSI) Reprod. Biol. Endocrinol. 9 2011 99
189. R. Pabuccu, and V. Gomel Reproductive outcome after hysteroscopic metroplasty in women with septate uterus and otherwise unexplained infertility Fertil. Steril. 81 2004 1675 1678
190. S. Pace, P. Stentella, R. Catania, P.L. Palazzetti, and A. Frega Endoscopic treatment of intrauterine adhesions Clin. Exp. Obstet. Gynecol. 30 2003 26 28
191. E.G. Papanikolaou, E.M. Kolibianakis, H. Tournaye, C.A. Venetis, H. Fatemi, B. Tarlatzis, and P. Devroey Live birth rates after transfer of equal number of blastocysts or cleavage-stage embryos in IVF. A systematic review and meta-analysis Hum. Reprod. 23 2008 91 99
192. R.J. Paulson, M.V. Sauer, and R.A. Lobo Factors affecting embryo implantation after human in vitro fertilization: a hypothesis Am. J. Obstet. Gynecol. 163 1990 2020 2023
193. T. Pehlivan, C. Rubio, L. Rodrigo, J. Romero, J. Remohi, C. Simon, and A. Pellicer Impact of preimplantation genetic diagnosis on IVF outcome in implantation failure patients Reprod. Biomed. Online 6 2003 232 237
194. A.S. Penzias Recurrent IVF failure: other factors Fertil. Steril. 97 2012 1033 1038
195. C.G. Petersen, A.L. Mauri, R.L. Baruffi, J.B. Oliveira, F.C. Massaro, K. Elder, and J.G. Franco Jr. Implantation failures: success of assisted hatching with quarter-laser zona thinning Reprod. Biomed. Online 10 2005 224 229
196. J.Y. Phelps, L. Figueira-Armada, A.S. Levine, N.P. Vlahos, D. Roshanfekr, H.A. Zacur, and J.E. Garcia Exogenous luteinizing hormone (LH) increases estradiol response patterns in poor responders with low serum LH concentrations J. Assist. Reprod. Genet. 16 1999 363 368
197. N. Potdar, T. Gelbaya, and L.G. Nardo Endometrial injury to overcome recurrent embryo implantation failure: a systematic review and meta-analysis Reprod. Biomed. Online. 25 2012 561 571
198. R.J. Potts, C.J. Newbury, G. Smith, L.J. Notarianni, and T.M. Jefferies Sperm chromatin damage associated with male smoking Mutat. Res. 423 1999 103 111
199. K.J. Printen, and D. Scott Pregnancy following gastric bypass for the treatment of morbid obesity Am. Surg. 48 1982 363 365
200. E.A. Pritts, W.H. Parker, and D.L. Olive Fibroids and infertility: an updated systematic review of the evidence Fertil. Steril. 91 2009 1215 1223
201. H.S. Qublan, S.S. Eid, H.A. Ababneh, Z.O. Amarin, A.Z. Smadi, F.F. Al-Khafaji, and Y.S. Khader Acquired and inherited thrombophilia: implication in recurrent IVF and embryo transfer failure Hum. Reprod. 21 2006 2694 2698
202. H. Qublan, Z. Amarin, M. Al-Qudah, F. Diab, M. Nawasreh, S. Malkawi, and M. Balawneh Luteal phase support with GnRH-a improves implantation and pregnancy rates in IVF cycles with endometrium of < or = 7 mm on day of egg retrieval Hum. Fertil. (Camb.) 11 2008 43 47
203. J. Rabinovici, M. David, H. Fukunishi, Y. Morita, B.S. Gostout, E.A. Stewart MRgFUS Study Group Pregnancy outcome after magnetic resonance-guided focused ultrasound surgery (MRgFUS) for conservative treatment of uterine fibroids Fertil. Steril. 93 2010 199 209
204. C. Racowsky, K.V. Jackson, N.A. Cekleniak, J.H. Fox, M.D. Hornstein, and E.S. Ginsburg The number of eight-cell embryos is a key determinant for selecting day 3 or day 5 transfer Fertil. Steril. 73 2000 558 564
205. F. Raga, C. Bauset, J. Remohi, F. Bonilla-Musoles, C. Simon, and A. Pellicer Reproductive impact of congenital Müllerian anomalies Hum. Reprod. 12 1997 2277 2281
206. G.A. Rama Raju, G. Shashi Kumari, K.M. Krishna, G.J. Prakash, and K. Madan Assessment of uterine cavity by hysteroscopy in assisted reproduction programme and its influence on pregnancy outcome Arch. Gynecol. Obstet. 2006 160 164
207. A. Raziel, S. Friedler, M. Schachter, E. Kasterstein, D. Strassburger, and R. Ron-EI Increased frequency of female partner chromosomal abnormalities in patients with high-order implantation failure after in vitro fertilization Fertil. Steril. 78 2002 515 519
208. A. Raziel, M. Schachter, D. Strassburger, O. Bern, R. Ron-EI, and S. Friedler Favorable influence of local injury to the endometrium in intracytoplasmic sperm injection patients with high-order implantation failure Fertil. Steril. 87 2007 198 201
209. C. Reinhold, S. McCarthy, P.M. Bret, A. Mehio, M. Atri, R. Zakarian, Y. Glaude, L. Liang, and R.J. Seymour Diffuse adenomyosis: comparison of endovaginal US and MR imaging with histopathologic correlation Radiology 199 1996 151 158
210. S.S. Richlin, S. Ramachandran, A. Shanti, A.A. Murphy, and S. Parthasarathy Glycodelin levels in uterine flushings and in plasma of patients with leiomyomas and polyps: implications for implantation Hum. Reprod. 17 2002 2742 2747
211. Royal College of Obstetricians and Gynaecologists. Greentop Guidelines. Classification of Evidence Levels. www.rcog.org.uk/guidelines.
212. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group, 2004. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS).
213. A.W. Sagoskin, B.A. Lessey, G.L. Mottla, K.S. Richter, R.J. Chetkowski, A.S. Chang, M.J. Levy, and R.J. Stillman Salpingectomy or proximal tubal occlusion of unilateral hydrosalpinx increases the potential for spontaneous pregnancy Hum. Reprod. 18 2003 2634 2637
214. T. Said, A. Agarwal, S. Grunewald, M. Rasch, T. Baumann, C. Kriegel, L. Li, H.J. Glander, A.J. Thomas Jr., and U. Paasch Selection of nonapoptotic spermatozoa as a new tool for enhancing assisted reproduction outcomes: an in vitro model Biol. Reprod. 74 2006 530 537
215. T.M. Said, S. Grunewald, U. Paasch, H.J. Glander, T. Baumann, C. Kriegel, L. Li, and A. Agarwal Advantage of combining magnetic cell separation with sperm preparation techniques Reprod. Biomed. Online 10 2005 740 746
216. D. Sakkas, and J.G. Alvarez Sperm DNA fragmentation: mechanisms of origin, impact on reproductive outcome, and analysis Fertil. Steril. 93 2010 1027 1036
217. D. Sakkas, and D.K. Gardner Noninvasive methods to assess embryo quality Curr. Opin. Obstet. Gynecol. 17 2005 283 288
218. H.N. Sallam, A.F. Agameya, A.F. Rahman, F. Ezzeldin, and A.N. Sallam Impact of technical difficulties, choice of catheter, and the presence of blood on the success of embryo transfer-experience from a single provider J. Assist. Reprod. Genet. 20 2003 135 142
219. H.N. Sallam, Y. El-Kassar, A. Hany Abdel-Rahman, A. Agameya, A. Farraq, and A. Shams Glucose consumption and total protein production by preimplantation embryos in women with the polycystic ovary syndrome Fertil. Steril. 86 Suppl. 3 2006 S462 S463
220. H.N. Sallam, J.A. Garcia-Velasco, S. Dias, and A. Arici Long-term pituitary down-regulation before in vitro fertilization (IVF) for women with endometriosis Cochrane Database Syst. Rev. 2006 CD004635
221. L.A. Schieve, S.F. Meikle, H.B. Peterson, G. Jeng, N.M. Burnett, and L.S. Wilcox Does assisted hatching pose a risk for monozygotic twinning in pregnancies conceived through in vitro fertilization? Fertil. Steril. 74 2000 288 294
222. W.R. Schoolcraft, E. Fragouli, I. Stevens, S. Munné, M. Katz-Jaffe, and D. Wells Clinical application of comprehensive chromosomal screening at the blastocyst stage Fertil. Steril. 94 2010 1700 1706
223. L. Scott, J. Berntsen, D. Davies, J. Gundersen, J. Hill, and N. Ramsing Symposium: innovative techniques in human embryo viability assessment. Human oocyte respiration-rate measurement-potential to improve oocyte and embryo selection? Reprod. Biomed. Online 17 2008 461 469
224. M.M. Seif, E.C. Edi-Osagie, C. Farquhar, L. Hooper, D. Blake, and P. McGinlay Assisted hatching on assisted conception (IVF and ICSI) Cochrane Database Syst. Rev. 2005 CD001894
225. E. Seli, U.A. Kayisli, H. Cakmak, O. Bukulmez, I. Bildirici, O. Guzeloglu-Kayisli, and A. Arici Removal of hydrosalpinges increases endometrial leukaemia inhibitory factor (LIF) expression at the time of the implantation window Hum. Reprod. 20 2005 3012 3017
226. K. Sharif, M. Afnan, and W. Lenton Mock embryo transfer with a full bladder immediately before the real transfer for in-vitro fertilization treatment: the Birmingham experience of 113 cases Hum. Reprod. 10 1995 1715 1718
227. K. Sharif, M. Afnan, W. Lenton, D. Bilalis, M. Hunjan, and Y. Khalaf Transmyometrial embryo transfer after difficult immediate mock transcervical transfer Fertil. Steril. 65 1996 1071 1074
228. E. Sheiner, A. Levy, D. Silverberg, T.S. Menes, I. Levy, M. Katz, and M. Mazor Pregnancy after bariatric surgery is not associated with adverse perinatal outcome Am. J. Obstet. Gynecol. 190 2004 1335 1340
229. G. Sher, and J.D. Fisch Vaginal sildenafil (Viagra): a preliminary report of a novel method to improve uterine artery blood flow and endometrial development in patients undergoing IVF Hum. Reprod. 15 2000 806 809
230. G. Sher, and J.D. Fisch Effect of vaginal sildenafil on the outcome of in vitro fertilization (IVF) after multiple IVF failures attributed to poor endometrial development Fertil. Steril. 78 2002 1073 1076
231. T. Shokeir, and M. Abdelshaheed Sonohysterography as a first-line evaluation for uterine abnormalities in women with recurrent failed in vitro fertilization-embryo transfer Fertil. Steril. 91 2009 1321 1322
232. T.A. Shokeir, H.M. Shalan, and M.M. El-Shafei Significance of endometrial polyps detected hysteroscopically in eumenorrheic infertile women J. Obstet. Gynaecol. Res. 30 2004 84 89
233. T. Shokeir, M. El-Shafei, H. Yousef, A.F. Allam, and E. Sadek Submucous myomas and their implications in the pregnancy rates of patients with otherwise unexplained primary infertility undergoing hysteroscopic myomectomy: a randomized matched control study Fertil. Steril. 94 2010 724 729
234. A. Simon, and N. Laufer Assessment and treatment of repeated implantation failure (RIF) J. Assist. Reprod. Genet. 29 2012 1227 1239
235. A. Simon, and N. Laufer Repeated implantation failure: clinical approach Fertil. Steril. 97 2012 1039 1043
236. A. Simur, S. Ozdemir, H. Acar, M.C. Colakoglu, H. Gorkemli, O. Balci, and S. Nergis Repeated in vitro fertilization failure and its relation with thrombophilia Gynecol. Obstet. Invest. 67 2009 109 112
237. V. Singhal, T.C. Li, and I.D. Cooke An analysis of factors influencing the outcome of 232 consecutive tubal microsurgery cases Br. J. Obstet. Gynaecol. 98 1991 628 636
238. S.R. Soares, M.M. Barbosa dos Reis, and A.F. Camargos Diagnostic accuracy of sonohysterography, transvaginal sonography, and hysterosalpingography in patients with uterine cavity diseases Fertil. Steril. 73 2000 406 411
239. A. Souza Setti, R.C. Ferreira, D. Paes de Almeida Ferreira Braga, R. de Cassia Savio Figueira, A. Iaconelli Jr., and E. Borges Jr. Intracytoplasmic sperm injection outcome versus intracytoplasmic morphologically selected sperm injection outcome: a meta-analysis Reprod. Biomed. Online 21 2010 450 455
240. M.C. Sowter, V.A. Akande, J.A. Williams, and M.G. Hull Is the outcome of in-vitro fertilization and embryo transfer treatment improved by spontaneous or surgical drainage of a hydrosalpinx? Hum. Reprod. 12 1997 2147 2150
241. S.D. Spandorfer, P.H. Chung, I. Kligman, H.C. Liu, O.K. Davis, and Z. Rosenwaks An analysis of the effect of age on implantation rates J. Assist. Reprod. Genet. 17 2000 303 306
242. B. Spiewankiewicz, J. Stelmachow, W. Sawicki, K. Cendrowski, P. Wypych, and K. Swiderska The effectiveness of hysteroscopic polypectomy in cases of female infertility Clin. Exp. Obstet. Gynecol. 30 2003 23 25
243. E.K. Steele, N. McClure, R.J. Maxwell, and S.E. Lewis A comparison of DNA damage in testicular and proximal epididymal spermatozoa in obstructive azoospermia Mol. Hum. Reprod. 5 1999 831 835
244. M.D. Stephenson, and M.R. Fluker Treatment of repeated unexplained in vitro fertilization failure with intravenous immunoglobulin: a randomized, placebo-controlled Canadian trial Fertil. Steril. 74 2000 1108 1113
245. C. Stern, L. Chamley, L. Hale, M. Kloss, A. Speirs, and H.W. Baker Antibodies to beta2 glycoprotein I are associated with in vitro fertilization implantation failure as well as recurrent miscarriage: results of a prevalence study Fertil. Steril. 70 1998 938 944
246. C. Stern, M. Pertile, H. Norris, L. Hale, and H.W. Baker Chromosome translocations in couples with in-vitro fertilization implantation failure Hum. Reprod. 14 1999 2097 2101
247. C. Stern, L. Chamley, H. Norris, L. Hale, and H.W. Baker A randomized, double-blind, placebo-controlled trial of heparin and aspirin for women with in vitro fertilization implantation failure and antiphospholipid or antinuclear antibodies Fertil. Steril. 80 2003 376 383
248. K. Sterzik, E. Strehler, M. De Santo, N. Trumpp, M. Abt, B. Rosenbusch, and A. Schneider Influence of smoking on fertility in women attending an in vitro fertilization program Fertil. Steril. 65 1996 810 814
249. D.W. Stovall, S.B. Parrish, B.J. Van Voorhis, S.J. Hahn, A.E. Sparks, and C.H. Syrop Uterine leiomyomas reduce the efficacy of assisted reproduction cycles: results of a matched follow-up study Hum. Reprod. 13 1998 192 197
250. A. Strandell, A. Lindhard, U. Waldenstrom, J. Thorburn, P.O. Janson, and L. Hamberger Hydrosalpinx and IVF outcome: a prospective, randomized multicentre trial in Scandinavia on salpingectomy prior to IVF Hum. Reprod. 14 1999 2762 2769
251. A. Strandell, A. Lindhard, and I. Eckerlund Cost-effectiveness analysis of salpingectomy prior to IVF, based on a randomized controlled trial Hum. Reprod. 20 2005 3284 3292
252. R. Suganuma, R. Yanagimachi, and M.L. Meistrich Decline in fertility of mouse sperm with abnormal chromatin during epididymal passage as revealed by ICSI Hum. Reprod. 20 2005 3101 3108
253. S.K. Sunkara, and K.S. Khan Adenomyosis and female fertility: a critical review of the evidence J. Obstet. Gynaecol. 32 2012 113 116
254. S.K. Sunkara, M. Khairy, T. El-Toukhy, Y. Khalaf, and A. Coomarasamy The effect of intramural fibroids without uterine cavity involvement on the outcome of IVF treatment: a systematic review and meta-analysis Hum. Reprod. 25 2010 418 429
255. E.S. Surrey, and W.B. Schoolcraft Evaluating strategies for improving ovarian response of the poor responder undergoing assisted reproductive techniques Fertil. Steril. 73 2000 667 676
256. E.S. Surrey, A.K. Lietz, and W.B. Schoolcraft Impact of intramural leiomyomata in patients with a normal endometrial cavity on in vitro fertilization-embryo transfer cycle outcome Fertil. Steril. 75 2001 405 410
257. B.K. Tan, P. Vandekerckhove, R. Kennedy, and S.D. Keay Investigation and current management of recurrent IVF treatment failure in the UK BJOG 112 2005 773 780
258. H. Taylor The role of HOX genes in human implantation Hum. Reprod. Update 6 2000 75 79
259. E. Taylor, and V. Gomel The uterus and fertility Fertil. Steril. 89 2008 1 16
260. N. Thebault, P.L. Broux, L. Moy, and J. Vialard Utilization of Essure micro-insert for hydrosalpinx occlusion in infertile women J. Gynecol. Obstet. Biol. Reprod. 41 2012 145 150
261. C. Tomas, K. Tikkinen, L. Tuomivaara, J.S. Tapanainen, and H. Martikainen The degree of difficulty of embryo transfer is an independent factor for predicting pregnancy Hum. Reprod. 17 2002 2632 2635
262. M.J. Tomlinson, O. Moffatt, G.C. Manicardi, D. Bizzaro, M. Afnan, and D. Sakkas Interrelationships between seminal parameters and sperm nuclear DNA damage before and after density gradient centrifugation: implications for assisted conception Hum. Reprod. 16 2001 2160 2165
263. T.L. Toth, S. Oehninger, J.P. Toner, R.G. Brzyski, A.A. Acosta, and S.J. Muasher Embryo transfer to the uterus or the fallopian tube after in vitro fertilisation yields similar results Fertil. Steril. 52 1992 1113
264. K. Tremellen, and P. Russell Adenomyosis is a potential cause of recurrent implantation failure during IVF treatment Aust. N. Z. J. Obstet. Gynaecol. 51 2011 280 283
265. H. Tournaye, P. Devroey, M. Camus, M. Valkenburg, N. Bollen, and A.C. Van Steirteghem Zygote intrafallopian transfer or in vitro fertilisation and embryo transfer for the treatment of male factor infertility: a prospective randomised trial Fertil. Steril. 58 1992 350
266. B. Urman, K. Yakin, and B. Balaban Recurrent implantation failure in assisted reproduction: how to counsel and manage. B. Treatment options that have not been proven to benefit the couple Reprod. Biomed. Online 11 2005 382 391
267. B.J. Van Voorhis, J.D. Dawson, D.W. Stovall, A.E. Sparks, and C.H. Syrop The effects of smoking on ovarian function and fertility during assisted reproduction cycles Obstet. Gynecol. 88 1996 785 791
268. N.N. Varasteh, R.S. Neuwirth, B. Levin, and M.D. Keltz Pregnancy rates after hysteroscopic polypectomy and myomectomy in infertile women Obstet. Gynecol. 94 1999 168 171
269. M.F. Verberg, M.J. Eijkemans, N.S. Macklon, E.M. Heijnen, E.B. Baart, F.P. Hohmann, B.C. Fauser, and F.J. Broekmans The clinical significance of the retrieval of a low number of oocytes following mild ovarian stimulation for IVF: a meta-analysis Hum. Reprod. Update 15 2009 5 12
270. P. Vercellini, I. Cortesi, O. De Giorgi, D. Merlo, S.G. Carinelli, and P.G. Crosignani Transvaginal ultrasonography versus uterine needle biopsy in the diagnosis of diffuse adenomyosis Hum. Reprod. 13 1998 2884 2887
271. L. Voullaire, H. Slater, R. Williamson, and L. Wilton Chromosome analysis of blastomeres from human embryos by using comparative genomic hybridization Hum. Genet. 106 2000 210 217
272. T.A. Wadden, and G.D. Foster Behavioral treatment of obesity Med. Clin. North Am. 84 2000 441 461 vii
273. W. Wang, and J.H. Check Effect of corporal fibroids on outcome following embryo transfer in donor-oocyte recipients Clin. Exp. Obstet. Gynecol. 31 2004 263 264
274. L.Y. Wang, D.H. Wang, X.Y. Zou, and C.M. Xu Mitochondrial functions on oocytes and preimplantation embryos J. Zhejiang Univ. Sci. B 10 2009 483 492
275. A. Weissman, I. Eldar, A. Ravhon, G. Biran, J. Farhi, H. Nahum, A. Golan, and D. Levran Timing intra-fallopian transfer procedures Reprod. Biomed. Online 15 2007 445 450
276. A. Weissman, E. Horowitz, A. Ravhon, H. Nahum, A. Golan, and D. Levran Pregnancies and livebirths following ICSI with testicular spermatozoa after repeated implantation failure using ejaculated spermatozoa Reprod. Biomed. Online 17 2008 605 609
277. A. Weissman, E. Horowitz, A. Ravhon, H. Nahum, A. Golan, and D. Levran Zygote intrafallopian transfer among patients with repeated implantation failure Int. J. Gynaecol. Obstet. 120 2013 70 73
278. L. Werlin, I. Rodi, A. DeCherney, E. Marello, D. Hill, and S. Munné Preimplantation genetic diagnosis as both a therapeutic and diagnostic tool in assisted reproductive technology Fertil. Steril. 80 2003 467 468
279. L. Wilton, A. Thornhill, J. Traeger-Synodinos, K.D. Sermon, and J.C. Harper The causes of misdiagnosis and adverse outcomes in PGD Hum. Reprod. 24 2009 1221 1228
280. G.C. Windham, L. Fenster, and S.H. Swan Moderate maternal and paternal alcohol consumption and the risk of spontaneous abortion Epidemiology 3 1992 364 370
281. R.M. Winston, and R.A. Margara Microsurgical salpingostomy is not an obsolete procedure Br. J. Obstet. Gynaecol. 98 1991 637 642
282. C. Wood, R. McMaster, G. Rennie, A. Trounson, and J. Leeton Factors influencing pregnancy rates following in vitro fertilization and embryo transfer Fertil. Steril. 43 1985 245 250
283. Y.S. Yang, S. Melinda, H.N. Ho, J.L. Hwang, S.U. Chen, H.R. Lin, S.C. Huang, and T.Y. Lee Effect of the number and depth of embryos transferred and unilateral or bilateral transfer in tubal embryo transfer (TET) J. Assist. Reprod. Genet. 9 1992 534 538
284. H. Yarali, and O. Bukulmez The effect of intramural and subserous uterine fibroids on implantation and clinical pregnancy rates in patients having intracytoplasmic sperm injection Arch. Gynecol. Obstet. 266 2002 30 33
285. H. Yasmin, A. Nasir, and K.J. Noorani Hystroscopic management of Ashermans syndrome J. Pak. Med. Assoc. 57 2007 553 555
286. D. Yu, Y.M. Wong, Y. Cheong, E. Xia, and T.C. Li Asherman syndrome-one century later Fertil. Steril. 89 2008 759 779
287. F. Zegers-Hochschild, G.D. Adamson, J. de Mouzon, O. Ishihara, R. Mansour, K. Nygren, E. Sullivan, and S. Vanderpoel International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology Fertil. Steril. 92 2009 1520 1524
288. H.B. Zeyneloglu, A. Arici, and D.L. Olive Adverse effects of hydrosalpinx on pregnancy rates after in vitro fertilization-embryo transfer Fertil. Steril. 70 1998 492 499
289. L. Zhou, R. Li, R. Wang, H.X. Huang, and K. Zhong Local injury to the endometrium in controlled ovarian hyperstimulation cycles improves implantation rates Fertil. Steril. 89 2008 1166 1176
290. K.A. Zikopoulos, E.M. Kolibianakis, P. Platteau, L. de Munck, H. Tournaye, P. Devroey, and M. Camus Live delivery rates in subfertile women with Asherman's syndrome after hysteroscopic adhesiolysis using the resectoscope or the Versapoint system Reprod. Biomed. Online 8 2004 720 725
291. M. Zinger, J.H. Liu, and M.A. Thomas Successful use of vaginal sildenafil citrate in two infertility patients with Asherman's syndrome J. Womens Health (Larchmt) 15 2006 442 444