Identification of viable embryos in IVF by non-invasive measurement of amino acid turnover

Human Reproduction

Volumn 19, Issue 10, 2004, Pages 2319-2324

  Brison, Daniel R ^a   Houghton, F D ^b   Falconer, D ^c   Roberts, S A ^d   Hawkhead, J ^b   Humpherson, P G ^b   Lieberman, B A ^a,c   Leese, H J ^b  

^a ST MARY S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

^c BUPA Hospitals   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Amino acid; Developmental potential; Human preimplantation embryo selection; IVF

Indexed keywords

ASPARAGINE; CHORIONIC GONADOTROPIN; FOLLITROPIN; GLYCINE; LEUCINE;

ADULT; ARTICLE; CELL COUNT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; EMBRYO; EMBRYO CELL; EMBRYO CULTURE; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; FOLLITROPIN BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; OUTCOMES RESEARCH; PREGNANCY RATE; SCORING SYSTEM; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME;

EID: 6444230562     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/deh409     Document Type: Article

References (18)

1. Bergh T, Ericson A, Hillensjo T, Nygren KG and Wennerholm UB (1999) Deliveries and children born after in-vitro fertilisation in Sweden 1982-95: a retrospective cohort study. Lancet 354,1579-1585.
2. Ecker DJ, Stein P, Xu Z, Williams CJ, Kopf GS, Bilker WB, Abel T and Schultz RM (2004) Long-term effects of culture of preimplantation mouse embryos on behavior. Proc Natl Acad Sci USA 101,1595-1600.
3. ESHRE Campus Course Report (2001) Prevention of twin pregnancies after IVF/ICSI by single embryo transfer. Hum Reprod 16,790-800.
4. Gardner DK and Leese HJ (2000) Assessment of embryo metabolism and viability. In Trounson AO and Gardner DK (eds) Handbook of In Vitro Fertilisation, 2nd edn. CRC Press, Boca Raton, pp. 347-371.
5. Gardner DK and Schoolcraft WB (1999) Culture and transfer of human blastocysts. Curr Opin Obstet Gynecol 11,307-311.
6. Hamberger L and Hazekamp J (2002) Towards single embryo transfer in IVF. J Reprod Immunol 55,141-148.
7. Holm S (1979) A simple sequentially rejective multiple test procedure. Scand J Statist 6,65-70.
8. Houghton FD, Hawkhead JA, Humpherson PG, Hogg JE, Balen AH, Rutherford AJ and Leese HJ (2002) Non-invasive amino acid turnover predicts human embryo developmental capacity. Hum Reprod 17,999-1005 [Corrigenda (2003) 18, 1756-1757].
9. Human Fertilisation and Embryology Authority (2002) Patients' Guide to IVF Clinics.
10. Lieberman B (1998) An embryo too many? Hum Reprod 13,2664-2666.
11. Lieberman BA, Falconer D and Brison DR (2001) Presentation of in-vitro fertilisation results. Lancet 357,397.
12. Mugford M and Henderson J (1995) Resource implications of multiple births. In Ward HR and Whittle M (eds) Multiple Births RCOG, London, pp. 334-345.
13. Racowsky C, Jackson KV, Cekleniak NA, Fox JH, Hornstein MD and Ginsburg ES (2000) The number of eight-cell embryos is a key determinant for selecting day 3 or day 5 transfer. Fertil Steril 73,558-564.
14. Steer CV, Mills CL, Tan SL, Campbell S and Edwards RG (1992) The cumulative embryo score: a predictive embryo scoring technique to select the optimal number of embryos to transfer in an in-vitro fertilization and embryo transfer programme. Hum Reprod 7,117-119.
15. Templeton A (2000) Avoiding multiple pregnancies in ART: replace as many embryos as you like - one at a time. Hum Reprod 15,1662.
16. Troendle JF (1995) A stepwise resampling method of multiple hypothesis testing. J Am Statist Assoc 90,370-378.
17. Van Steirteghem AC, Liu J, Joris H, Nagy Z, Janssenswillen C, Tournaye H, Derde MP, Van Assche E and Devroey P (1993) Higher success rate by intracytoplasmic sperm injection than by subzonal insemination. Report of a second series of 300 consecutive treatment cycles. Hum Reprod 8,1055-1060.
18. Young LE, Sinclair KD and Wilmut I (1998) Large offspring syndrome in cattle and sheep. Rev Reprod 3,155-163.