Non-invasive amino acid turnover predicts human embryo developmental capacity

Human Reproduction

Volumn 17, Issue 4, 2002, Pages 999-1005

  Houghton, Franchesca D ^a   Hawkhead, Judith A ^a   Humpherson, Peter G ^a   Hogg, Jan E ^b   Balen, Adam H ^b   Rutherford, Anthony J ^b   Leese, Henry J ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b LEEDS GENERAL INFIRMARY   (United Kingdom)

Author keywords

Amino acids; Developmental potential; Human preimplantation embryo culture; IVF

Indexed keywords

ALANINE; AMINO ACID; ARGININE; ASPARAGINE; GLUTAMINE; LEUCINE; METHIONINE;

AMINO ACID TRANSPORT; ARTICLE; BIRTH RATE; BLASTOCYST; CELL CYCLE PHASE; CELL SELECTION; CELL VIABILITY; CHILDHOOD DISEASE; DEPLETION; DEVELOPMENTAL STABILITY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; FERTILIZATION IN VITRO; FUNCTIONAL MORPHOLOGY; GENE EXPRESSION PROFILING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; MULTIPLE PREGNANCY; NEWBORN MORTALITY; NON INVASIVE MEASUREMENT; PHYSICAL DISABILITY; PREDICTION; PREGNANCY RATE; PREIMPLANTATION EMBRYO; PREMATURITY; SCORING SYSTEM;

EID: 0036115698     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Purine utilisation, de novo synthesis and degradation in mouse preimplantation embryos
2. Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway
3. GnRH agonists and superovulation for assisted conception
4. Regulation of hamster embryo development in vitro by amino acids
5. Development of spare human preimplantation embryos in vitro: An analysis of the correlations among gross morphology, cleavage rates and development to the blastocyst stage
6. Human gene expression first occurs between the four- and eight-cell stages of preimplantation development
7. Selection criteria for human embryo transfer: A comparison of pyruvate uptake and morphology
8. Culture of human preimplantation embryos to the blastocyst stage: A comparison of 3 media
9. Osmolarity dependent glycine accumulation indicates a role for glycine as an organic osmolyte in early preimplantation mouse embryos
10. Glutamine improves human preimplantation development in vitro
11. Effects of taurine on human embryo development in vitro
12. Amino acids promote human blastocyst development
13. Can embryo metabolism be used for selecting bovine embryos before transfer?
14. Taurine acts as an osmolyte in human and mouse oocytes and embryos
15. Intracellular pH of the mouse preimplantation embryo: Amino acids act as buffers of intracellular pH
16. Amino acid uptake and protein synthesis in preimplantation mouse embryos
17. Metabolic regulation
18. Culture and selection of viable blastocysts: A feasible proposition for human IVF
19. Glycine transport by single human and mouse embryos
20. Maternal and fetal demands for nutrients: Significance of protein metabolism
21. Amino caid metabolism of bovine blastocysts derived from parthenogenetically activated or in vitro fertilised oocytes
22. Leucine regulates translation of specific mRNAs in L6 myoblasts through in mTOR-mediated changes in availability of eIF4E and phosphorylation of ribosomal protein S6
23. Differential regulation of mouse embryo development and viability by amino acids
24. Amino acids and vitamins prevent culture-induced metabolic perturbations and associated loss of viability of mouse blastocysts
25. Uptake of a mixture of amino acids by mouse blastocysts
26. Metabolism of the preimplantation mammalian embryo
27. The movement of amino acids into rabbit oviductal fluid
28. Regulation of amino acid-sensitive TOR signaling by leucine analogues in adipocytes
29. Amino acid content of preimplantation rabbit embryos and fluids of the reproductive tract
30. Effects of glucose, glutamine, ethylenediaminetetraacetic acid and oxygen tension on the concentration of reactive oxygen species and on development of the mouse preimplantation embryo in vitro
31. Consumption of amino acids by bovine preimplantation embryos
32. Blastocyst culture and transfer: Analysis of results and parameters affecting outcome in two in vitro fertilization programs
33. The cell biology of preimplantation development
34. Human tubal fluid: Production, nutrient composition and response to adrenergic agents
35. Comparison of pyruvate uptake by emrbyos derived from conception and non-conception natural cycles
36. Amino acid transport regulation and early embryo development
37. Amino acid transport regulation in preimplantation mouse embryos: Effects of amino acid content and pre- and pre-implantation development
38. Glycine protects preimplantation mouse conceptuses from a detrimental effect on development of the inorganic ions in oviductal fluid
39. Characterisation of L-arginine transporters in rat renal inner medullary collecting duct