Human dental pulp stem cells: From biology to clinical applications

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution

Volumn 312, Issue 5, 2009, Pages 408-415

  D'aquino, Riccardo ^a   de Rosa, Alfredo ^b   Laino, Gregorio ^b   Caruso, Filippo ^b   Guida, Luigi ^b   Rullo, Rosario ^b   Checchi, Vittorio ^c   Laino, Luigi ^a   Tirino, Virginia ^a   Papaccio, Gianpaolo ^a  

^a Sezione di Istologia ed Embriologia   (Italy)

^b Dipartimento di Discipline Odontostomatologiche   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BONE; CELL DIFFERENTIATION; CRYOPRESERVATION; CYTOLOGY; EMBRYO DEVELOPMENT; HUMAN; METHODOLOGY; NEURAL CREST; PHYSIOLOGY; PLURIPOTENT STEM CELL; PRENATAL DEVELOPMENT; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING; TOOTH FLORA; TOOTH PULP;

BONE AND BONES; CELL DIFFERENTIATION; CRYOPRESERVATION; DENTAL PULP; EMBRYONIC DEVELOPMENT; HUMANS; NEURAL CREST; PLURIPOTENT STEM CELLS; STEM CELL TRANSPLANTATION; TISSUE ENGINEERING; TOOTH GERM;

EID: 67651236870     PISSN: 15525007     EISSN: 15525015     Source Type: Journal    
DOI: 10.1002/jez.b.21263     Document Type: Article

References (46)

1. Batouli S, Miura M, Brahim J, Tsutsui TW, Fisher LW, Gronthos S, Robey PG, Shi S. 2003. Comparison of stemcell-mediated osteogenesis and dentinogenesis. J Dent Res 82:976-981.
2. Bosshardt DD. 2005. Are cementoblasts a subpopulation of osteoblasts or a unique phenotype? J Dent Res 84:390-406.
3. D'Aquino R, Graziano A, Sampaolesi M, Laino G, Pirozzi G, De Rosa A, Papaccio G. 2007. Human postnatal dental pulp cells co-differentiate into osteoblasts and endotheliocytes: a pivotal synergy leading to adult bone tissue formation. Cell Death Differ 14:1162-1171.
4. Fitzgerald M, Chiego Jr DJ, Heys DR. 1990. Autoradiographic analysis of odontoblast replacement following pulp exposure in primate teeth. Arch Oral Biol 35:707-715.
5. Goldberg M, Smith AJ. 2004. Cells and extracellular matrices of dentin and pulp: a biological basis for repair and tissue engineering. Crit Rev Oral Biol Med 15:13-27.
6. Grando Mattuella L, de Figueiredo JA, Nör JE, de Araujo FB, Fossati AC. 2007a. Vascular endothelial growth factor receptor-2 expression in the pulp of human primary and young permanent teeth. J Endod 33:1408-1412.
7. Grando Mattuella L, Westphalen Bento L, de Figueiredo JA, Nör JE, de Araujo FB, Fossati AC. 2007b. Vascular endothelial growth factor and its relationship with the dental pulp. J Endod 33:524-530. Review.
8. Graziano A, d'Aquino R, Cusella-de Angelis MG, Laino G, Piattelli A, Pacifici M, De Rosa A, Papaccio G. 2007. Concave pit-containing scaffold surfaces improve stem cell-derived osteoblast performance and lead to significant bone tissue formation. PLoS ONE 2:e496.
9. Graziano A, d'Aquino R, Cusella-De Angelis MG, De Francesco F, Giordano A, Laino G, Piattelli A, Traini T, De Rosa A, Papaccio G. 2008. Scaffold's surface geometry significantly affects human stem cell bone tissue engineering. J Cell Physiol 214:166-172.
10. Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. 2000. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA 97:13625-13630.
11. Gronthos S, Brahim J, Li W, Fisher LW, Cherman N, Boyde A, DenBesten P, Robey PG, Shi S. 2002. Stem cell properties of human dental pulp stem cells. J Dent Res 81:531-535.
12. Hosoya A, Nakamura H, Ninomiya T, Hoshi K, Yoshiba K, Yoshiba N, Takahashi M, Okabe T, Sahara N, Yamada H, Kasahara E, Ozawa H. 2007. Hard tissue formation in subcutaneously transplanted rat dental pulp. J Dent Res 86:469-474.
13. Hwang YC, Hwang IN, Oh WM, Park JC, Lee DS, Son HH. 2008. Influence of TGF-beta1 on the expression of BSP, DSP, TGF-beta1 receptor I and Smad proteins during reparative dentinogenesis. J Mol Histol 39:153-160.
14. Iohara K, Zheng L, Ito M, Tomokiyo A, Matsushita K, Nakashima M. 2006. Side population cells isolated from porcine dental pulp tissue with self-renewal and multipotency for dentinogenesis, chondrogenesis, adipogenesis, and neurogenesis. Stem Cells 24:2493-2503.
15. Jo YY, Lee HJ, Kook SY, Choung HW, Park JY, Chung JH, Choung YH, Kim ES, Yang HC, Choung PH. 2007. Isolation and characterization of postnatal stem cells from human dental tissues. Tissue Eng 13:767-773.
16. Kitagawa M, Ueda H, Iizuka S, Sakamoto K, Oka H, Kudo Y, Ogawa I, Miyauchi M, Tahara H, Takata T. 2007. Immortalization and characterization of human dental pulp cells with odontoblastic differentiation. Arch Oral Biol 52:727-731.
17. Laino G, d'Aquino R, Graziano A, Lanza V, Carinci F, Pirozzi G, Naro F, Papaccio G. 2005. Dental pulp stem cells can be detected in aged humans: an useful source f or livingautologous fibrous bone tissue (LAB). J Bone Miner Res 20:1394-1402.
18. Laino G, Graziano A, d'Aquino R, Pirozzi G, Lanza V, Valiante S, De Rosa A, Naro F, Vivarelli E, Papaccio G. 2006. An approachable human adult s tem cell source forhard-tissue engineering. J Cell Physiol 206:693-701.
19. Lesot H, Lisi S, Peterkova R, Peterka M, Mitolo V, Ruch JV. 2001. Epigenetic signals during odontoblast differentiation. Adv Dent Res 15:8-13.
20. Liu J, Jin T, Chang S, Ritchie HH, Smith AJ, Clarkson BH. 2007. Matrix and TGF- beta-related gene expression during human dental pulp stem cell (DPSC) mineralization. In Vitro Cell Dev Biol Anim 43:120-128.
21. Luisi SB, Barbachan JJ, Chies JA, Filho MS. 2007. Behavior of human dental pulp cells exposed to transforming growth factor-beta1 and acidic fibroblast growth factor in culture. J Endod 33:833-835.
22. Mao JJ, Giannobile WV, Helms JA, Hollister SJ, Krebsbach PH, Longaker MT, Shi S. 2006. Craniofacial tissue engineering by stem cells. J Dent Res 85:966-979. Review.
23. Miura M, Gronthos S, Zhao M, Lu B, Fisher LW, Robey PG, Shi S. 2003. SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA 100:5807-5812.
24. Nakashima M, Iohara K, Zheng L. 2006. Gene therapy for dentin regeneration with bone morphogenetic proteins. Curr Gene Ther 6:551-560. Review.
25. Otaki S, Ueshima S, Shiraishi K, Sugiyama K, Hamada S, Yorimoto M, Matsuo O. 2007. Mesenchymal progenitor cells in adult human dental pulp and their ability to form bone when transplanted into immunocompromised mice. Cell Biol Int 31:1191-1197.
26. Papaccio G, Graziano A, d'Aquino R, Graziano MF, Pirozzi G, Menditti D, De Rosa A, Carinci F, Laino G. 2006. Long-term cryopreservation of dental pulp stem cells (SBP-DPSCs) and their differentiated osteoblasts: a cell source for tissue repair. J Cell Physiol 208:319-325.
27. Pierdomenico L, Bonsi L, Calvitti M, Rondelli D, Arpinati M, Chirumbolo G, Becchetti E, Marchionni C, Alviano F, Fossati V, Staffolani N, Franchina M, Grossi A, Bagnara GP. 2005. Multipotent mesenchymal stem cells with immuno-suppressive activity can be easily isolated from dental pulp. Transplantation 80:836-842.
28. Pisterna GV, Siragusa M. 2007. CD44 Presence in inflamed pulp tissue. J Endod 33:1203-1207.
29. Seo BM, Miura M, Sonoyama W, Coppe C, Stanyon R, Shi S. 2005. Recovery of stem cells from cryopreserved periodontal ligament. J Dent Res 84:907-912.
30. Sinanan AC, Hunt NP, Lewis MP. 2004. Human adult craniofacial muscle-derived cells: neural-cell adhesion-molecule (NCAM; CD56)-expressing cells appear to contain multipotential stem cells. Biotechnol Appl Biochem 40:25-34.
31. Srisawasdi S, Pavasant P. 2007. Different roles of dexametha- sone on transforming growth factor-beta1-induced fibronectin and nerve growth factor expression in dental pulp cells. J Endod 33:1057-1060.
32. Tonomura A, Sumita Y, Ando Y, Iejima D, Kagami H, Honda MJ, Ueda M. 2007. Differential inducibility of human and porcine dental pulp-derived cells into odontoblasts. Connect Tissue Res 48:229-238.
33. Tran-Hung L, Mathieu S, About I. 2006. Role of human pulp fibroblasts in angiogenesis. J Dent Res 85:819-823.
34. Tran-Hung L, Laurent P, Camps J, About I. 2007. Quantifica- tion of angiogenic growth factors released by human dental cells after injury. Arch Oral Biol 53:9-13.
35. Trubiani O, Tripodi D, Delle Fratte T, Caputi S, Di Primio R. 2003. Human dental pulp vasculogenesis evaluated by CD34 antigen expression and morphological arrangement. J Dent Res 82:742-747.
36. Ueno A, Yamashita K, Miyoshi K, Horiguchi T, Ruspita I, Abe K, Noma T. 2006. Soluble matrix from osteoblastic cells induces mineralization by dental pulp cells. J Med Invest 53:297-302.
37. Wei X, Ling J, Wu L, Liu L, Xiao Y. 2007. Expression of mineralization markers in dental pulp cells. J Endod 33:703-708.
38. Yang X, van den Dolder J, Walboomers X., Zhang W, Bian Z, Fan, Jansen JA. 2007a. The odontogenic potential of STRO-1 sorted rat dental pulp stem cells in vitro. J Tissue Eng Regen Med 1:66-73.
39. Yang X, van der Kraan PM, van den Dolder J, Walboomers XF, Bian Z, Fan M, Jansen JA. 2007b. STRO-1 selected rat dental pulp stem cells transfected with adenoviral-mediated human bone morphogenetic protein 2 gene show enhanced odontogenic differentiation. Tissue Eng 13:2803-2812.
40. Yildirim S, Yapar M, Sermet U, Sener K, Kubar A. 2008. The role of dental pulp cells in resorption of deciduous teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:113-120.
41. Yu J, Deng Z, Shi J, Zhai H, Nie X, Zhuang H, Li Y, Jin Y. 2006. Differentiation of dental pulp stem cells into regular- shaped dentin-pulp complex induced by tooth germ cell conditioned medium. Tissue Eng 12:3097-3105.
42. Yuasa K, Fukumotom S, Kamasakim Y, Yamadam A, Fukumotom E, Kanaokam K, Saitom K, Harada Hm, Arikawa-Hirasawam E, Miyagoe-Suzukim Y, Takedam S, Okamotom K, Kato Y, Fujiwara T. 2004. Laminin alpha2 is essential for odontoblast differentiation regulating dentinsialoprotein expression. J Biol Chem 279: 10286-10292.
43. Zhang J, Niu C, Ye L, Huang H, He X, Tong WG, Ross J, Haug J, Johnson T, Feng JQ, Harris S, Wiedemann LM, Mishina Y, Li L. 2003. Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425:836-840.
44. Zhang W, Walboomers X, van Kuppevelt TH, Daamen WF, Bian Z, Jansen JA. 2006a. The performance of human dental pulp stem cells on different three-dimensional scaffold materials. Biomaterials 27: 5658-5668.
45. Zhang W, Walboomers XF, Shi S, Fan M, Jansen JA. 2006b. Multilineage differentiation potential of stem cells derived from human dental pulp after cryopreservation. Tissue Eng 12:2813-2823.
46. Zheng L, Iohara K, Ishikawa M, Into T, Takano-Yamamoto T, Matsushita K, Nakashima M. 2007. Runx3 negatively regulates Osterix expression in dental pulp cells. Biochem J 405:69-75.