Pathobiology of cancer chemotherapy-induced peripheral neuropathy (CIPN)

Frontiers in Pharmacology

Volumn 4 DEC, Issue , 2013, Pages

  Han, Yaqin ^a   Smith, Maree T ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Chemotherapy induced peripheral neuropathy (CIPN); Intraepidermal nerve fiber (IENF) degeneration; Loss of heat sensitivity; Mitochondrial dysfunction; Oxidative stress

Indexed keywords

2 AMINO 4 (METHYLSULFONYL)BUTYRYLGLUTAMYLHISTIDYLPHENYLALANYL DEXTRO LYSYLPHENYLALANINE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; ACETYLCYSTEINE; AMIFOSTINE; ANALGESIC AGENT; BORTEZOMIB; CALCIUM; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DOCETAXEL; FLUOROURACIL; FOLINIC ACID; GLUTATHIONE; LEVACECARNINE; MITOCHONDRIAL DNA; MYELIN; OLESOXIME; OXALIPLATIN; PACLITAXEL; PLACEBO; SILIBININ; TAXANE DERIVATIVE; THIOCTIC ACID; VANILLOID RECEPTOR 1; VINCRISTINE;

ADVERSE DRUG REACTION; ANALGESIA; CALCIUM BALANCE; CANCER CHEMOTHERAPY; CELL VACUOLE; CHEMOSENSITIZATION; CHEMOTHERAPY INDUCED PERIPHERAL NEUROPATHY; DESENSITIZATION; DISEASE COURSE; DISEASE SEVERITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; DRUG EFFICACY; DRUG SAFETY; HEAT SENSITIVITY; HUMAN; MITOCHONDRION SWELLING; MYELINATED NERVE; NERVE FIBER DEGENERATION; NEUROANATOMY; NEUROPATHY; NONHUMAN; NONMYELINATED NERVE; OXIDATIVE STRESS; PAIN; PATHOGENESIS; PATHOPHYSIOLOGY; PERIPHERAL NEUROPATHY; PROTEIN STRUCTURE; REVIEW; SENSORY NERVE; SINGLE DRUG DOSE; SPINAL CORD DISEASE; SYMPTOM;

EID: 84891718636     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2013.00156     Document Type: Review

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