Role of MAPKs in platinum-induced neuronal apoptosis

NeuroToxicology

Volumn 30, Issue 2, 2009, Pages 312-319

  Scuteri, Arianna ^a   Galimberti, Alessia ^a   Maggioni, Daniele ^a   Ravasi, Maddalena ^a   Pasini, Silvia ^a   Nicolini, Gabriella ^a   Bossi, Mario ^a   Miloso, Mariarosaria ^a   Cavaletti, Guido ^a   Tredici, Giovanni ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

Cisplatin; Dorsal root Ganglion neurons; MAPK; Neuronal toxicity; Oxaliplatin

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CISPLATIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OXALIPLATIN; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; PLATINUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; IMMUNOBLOTTING; NERVE CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL GANGLION; ANIMAL; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; FEMALE; PHYSIOLOGY; PREGNANCY; SPRAGUE DAWLEY RAT; TOXICITY;

ANIMALS; APOPTOSIS; CELLS, CULTURED; FEMALE; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PLATINUM; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 61849088961     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2009.01.003     Document Type: Article

References (54)

1. Ahn N.G., Nahreini T.S., Tolwinski N.S., and Resing K.A. Pharmacologic inhibitors of MKK1 and MKK2. Methods Enzymol 332 (2001) 417-431
2. Bennett B.L., Sasaki D.T., Murray B.W., O'Leary E.C., Sakata S.T., Xu W., et al. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci USA 20 (2001) 13681-13686
3. Cavaletti G., Miloso M., Nicolini G., Scuteri A., and Tredici G. Emerging role of mitogen-activated protein kinases in peripheral neuropathies. Peripher Nerv Syst 12 (2007) 175-194
4. Cavaletti G., Tredici G., Petruccioli M.G., Dondè E., Tredici P., Marmiroli P., et al. Effects of different schedules of oxaliplatin treatment on the peripheral nervous system of the rat. Eur J Cancer 37 (2001) 257-2463
5. Choi B.K., Choi C.H., Oh H.L., and Kim Y.K. Role of MAPK in ceramide-induced cell death in primary cultured astrocytes from mouse embryonic brain. Neurotoxicology 25 (2004) 915-924
6. Chwang W.B., O'Riordan K.J., Levenson J.M., and Sweatt J.D. ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning. Learn Mem 13 (2006) 322-328
7. Coffey E., Hongisto V., Dickens M., Davis R.J., and Courtney M.J. Dual roles for c-Jun N-terminal kinases in development and stress responses in cerebellar granule neurons. J Neurosci 20 (2000) 7602-7613
8. Colucci-D'Amato L., Perrone-Capano C., and di Porzio U. Chronic activation of ERK and neurodegenerative diseases. Bioassays 25 (2003) 1085-1095
9. Cuenda A., Rouse J., Doza Y.N., Meier R., Cohen P., Gallagher T.F., et al. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett 8 (1995) 229-233
10. Davies A.M. The Bcl-2 family of proteins, and the regulation of neuronal survival. TINS 18 (1995) 355-358
11. Donzelli E., Carfì M., Miloso M., Strada A., Galbiati S., and Tredici G. Neurotoxicity of platinum compounds: comparison of effects of cisplatin and oxaliplatin on the human neuroblastoma cell line SH-SY5Y. J Neurooncol 67 (2004) 65-73
12. Fisher S., McDonald E., Gross L., and Windebank A.J. Alterations in cell cycle regulation underlie cisplatin induced apoptosis of dorsal root ganglion neurons in vivo. Neurobiol Dis 8 (2001) 1027-1035
13. Giasson B.I., Bruening W., Durham H.D., and Mushynski W.E. Activation of stress-activated protein kinases correlates with neurite outgrowth induced by protease inhibition in PC12 cells. J Neurochem 72 (1999) 1081-1087
14. Gill J.S., and Windebank A.J. Cisplatin-induced apoptosis in rat dorsal root ganglion neurons is associated with attempted entry into the cell cycle. J Clin Inv 101 (1998) 2842-2851
15. Gozdz A., Habas J., Jaworski M., Zielinska J., Albrecht M., Chlystun A., et al. Role of N-methyl-d-aspartate receptors in the neuroprotective activation of extracellular signal-regulated kinase 1/2 by cisplatin. J Biol Chem 278 (2003) 43663-43671
16. Grewal S.S., York R.D., and Stork P.J. Extracellular-signal-regulated kinase signalling in neurons. Curr Opin Neurobiol 9 (1999) 544-553
17. Grolleau F., Gamelin L., Boisdron-Celle M., Lapide B., Pelhate M., and Gamelin E. A possible explanation for a neurotoxic effect of the anticancer agent oxaliplatin on neuronal voltage-gated sodium channels. J Neurophysiol 85 (2001) 2293-2297
18. Hao W., Takano T., Guillemette J., Papillon J., Ren G., and Cybulsky A.V. Induction of apoptosis by the Ste20-like kinase SLK, a germinal center kinase that activates apoptosis signal-regulating kinase and p38. J Biol Chem 281 (2006) 3075-3084
19. Hershberger P.A., McGuire T.F., Yu W., Zuhowski E.G., Schellens J.H., Egorin M.J., et al. Cisplatin potentiates 1,25-dihydroxyvitamin D3-induced apoptosis in association with increased mitogen-activated protein kinase kinase kinase 1 (MEKK-1) expression. Mol Cancer Ther 1 (2002) 821-829
20. Ishikawa Y., Kusaka E., Enokido Y., Ikeuchi T., and Hatanaka H. Regulation of Bax translocation through phosphorylation at Ser-70 of Bcl-2 by MAP kinase in NO-induced neuronal apoptosis. Mol Cell Neurosci 24 (2003) 451-459
21. Kenney A.M., and Kocsis J.D. Peripheral axotomy induces long-term c-Jun amino-terminal kinase-1 activation and activator protein-1 binding activity by c-Jun and junD in adult rat dorsal root ganglia in vivo. J Neurosci 18 (1998) 1318-1328
22. Lewis T.S., Shapiro P.S., and Ahn N.G. Signal transduction through MAP kinase cascades. Adv Cancer Res 74 (1998) 49-139
23. McDonald E.S., Randon K.R., Knight A., and Windebank A.J. Cisplatin preferentially binds to DNA in dorsal root ganglion neurons in vitro and in vivo: a potential mechanism for neurotoxicity. Neurobiol Dis 18 (2005) 305-313
24. Middlemas A., Delacroix J.D., Sayers N.M., Tomlinson D.R., and Fernyhough P. Enhanced activation of axonally transported stress-activated protein kinases in peripheral nerve in diabetic neuropathy is prevented by neurotrophin-3. Brain 126 (2003) 1671-1682
25. Miloso M., and Tredici G. MAPKs and their inhibitors in neuronal differentiation. CEI 3 (2007) 298-308
26. Miloso M., Villa D., Crimi M., Galbiati S., Donzelli E., Nicolini G., et al. Retinoic acid-induced neuritogenesis of human neuroblastoma SH-SY5Y cells is ERK independent and PKC dependent. J Neurosci Res 75 (2004) 241-252
27. Misset J.L. Oxaliplatin in practice. Br J Cancer 77 (1998) 4-7
28. Myers R.R., Sekiguchi Y., Kikuchi S., Scott B., Medicherla S., Protter A., et al. Inhibition of p38 MAP kinase activity enhances axonal regeneration. Exp Neurol 2 (2003) 606-614
29. Nakahara S., Yone K., Sakou T., Wada S., Nagamine T., Nuyama T., et al. Induction of apoptosis signal regulating kinase 1 (ASK1) after spinal cord injury in rats: possible involvement of ASK1-JNK and -p38 pathways in neuronal apoptosis. J Neuropathol Exp Neurol 58 (1999) 442-450
30. Nehmé A., Baskaran R., Nebel S., Fink D., Howell S.B., Wang J.Y., et al. Induction of JNK and c-Abl signalling by cisplatin and oxaliplatin in mismatch repair-proficient and -deficient cells. Br J Cancer 7-8 (1999) 1104-1110
31. Nicolini G., Rigolio R., Scuteri A., Miloso M., Saccomanno D., Cavaletti G., et al. Effects of trans-resveratrol on signal transduction pathways involved in paclitaxel-induced apoptosis in human neuroblastoma SH-SY5Y cells. Neurochem Int 42 (2003) 419-429
32. Oh H.L., Seok J.Y., Kwon C.H., Kang S.K., and Kim Y.K. Role of MAPK in ceramide-induced cell death in primary cultured astrocytes from mouse embryonic brain. Neurotoxicology 27 (2006) 31-38
33. Ozaki I., Tani E., Ikemoto H., Kitagawa H., and Fujikawa H. Activation of stress-activated Protein Kinase/c-Jun NH2-terminal Kinase and p38 Kinase in calphostin C-induced apoptosis requires caspase-3-like proteases but is dispensable for cell death. J Biol Chem 274 (1999) 5310-5317
34. Persons D.L., Yazlovitskaya E.M., Cui W., and Pelling J.C. Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin. Clin Cancer Res 5 (1999) 1007-1014
35. Potapova O., Haghighi A., Bost F., Liu C., Birrer M.J., Gjerset R., et al. The jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin. J Biol Chem 272 (1997) 14041-14044
36. Price S.A., Agthong S., Middlemas A., and Thomlinson D.R. Mitogen-activated protein kinase p38 mediates reduced nerve conduction velocity in experimental diabetic neuropathy. Diabetes 53 (2004) 1851-1856
37. Purves T., Middlemas A., Agthong S., Jude E.B., Boulton A.J.M., Fernyhough P., et al. A role for mitogen-activated protein kinases in the etiology of diabetic neuropathy. FASEB 15 (2001) 2508-2513
38. Quasthoff S., and Hartung H.P. Chemotherapy-induced peripheral neuropathy. J Neurol 249 (2002) 9-17
39. Raingeaud J., Gupta S., Rogers J.S., Dickens M., Han J., Ulevitch R.J., et al. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 270 (1995) 7420-7426
40. Ribeiro M.J., Schofield M.G., Kemenes I., O'Shea M., Kemenes G., and Benjamin P.R. Activation of MAPK is necessary for long-term memory consolidation following food-reward conditioning. Learn Mem 12 (2005) 538-545
41. Scuteri A., Cassetti A., and Tredici G. Adult mesenchymal stem cells rescue dorsal root ganglia neurons from dying. Brain Res 20 (2006) 75-81
42. Scuteri A., Nicolini G., Miloso M., Bossi M., Cavaletti G., Windebank A.J., et al. Paclitaxel toxicity in post-mitotic dorsal root ganglion (DRG) cells. Anticancer Res 26 (2006) 1065-1070
43. Scuteri A., Nicolini G., Canta A., Galbiati S., Giardini A., Losa D., et al. MAPK involvement in platinum compounds toxicity on rat DRG neurons. J Peripheral Nervous Syst 10 1 (2005)
44. Segal R.A., and Greenberg M.E. Intracellular signaling pathways activated by neurotrophic factors. Ann Rev Neurosci 19 (1996) 463-489
45. Stoica B.A., Movsesyan V.A., Knoblach S.M., and Faden A.I. Ceramide induces neuronal apoptosis through mitogen-activated protein kinases and causes release of multiple mitochondrial proteins. Mol Cell Neurosci 29 (2005) 355-371
46. Sturla L.M., Cowan C.W., Guenther L., Castellino R.C., Kim J.Y., and Pomeroy S.L. A novel role for extracellular signal-regulated kinase 5 and myocyte enhancer factor 2 in medulloblastoma cell death. Cancer Res 65 (2005) 5683-5689
47. Takeda K., and Ichijo H. Neuronal p38 MAPK signaling: an emergent regulator of cell fate and function in the nervous system. Genes Cells 7 (2002) 1099-1111
48. Thomas M.G., and Huganir R.L. MAPK cascade signalling and synaptic plasticity. Nature Rev 5 (2004) 173-183
49. To K.K., Wang X., Yu C.W., Ho Y.P., and Au-Yeung S.C. Protein phosphatase 2A inhibition and circumvention of cisplatin cross-resistance by novel TCM-platinum anticancer agents containing demethylcantharidin. Bioorg Med Chem 12 (2004) 4565-4573
50. Waetzig V., and Herdegen T. MEKK1 controls neurite regrowth after experimental injury by balancing ERK1/2 and JNK2 signaling. Mol Cell Neurosci 30 (2005) 67-78
51. Wang J., Zhou J.Y., and Wu G.S. ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells. Cancer Res 15 (2007) 11933-11941
52. Wang Z., Xu J., Zhou J.Y., Liu Y., and Wu G.S. Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance. Cancer Res 1 (2006) 8870-8877
53. Williams T.M., Ndifor A.M., Near J.T., and Reams-Brown R.R. Lead enhances NGF-induced neurite outgrowth in PC12 cells by potentiating ERK/MAPK activation. Neurotoxicology 21 (2000) 1081-1089
54. Xiao Y.Q., Malcolm K., Worthen G.S., Gardai S., Schiemann W.P., Fadok V.A., et al. Cross-talk between ERK and p38 MAPK mediates selective suppression of pro-inflammatory cytokines by transforming growth factor-beta. J Biol Chem 17 (2002) 14884-14893