Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial cells: Role of increased dna damage and decreased dna repair capacity in microvascular radiosensitivity

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 68, Issue 12 A, 2013, Pages 1443-1457

  Ungvari, Zoltan ^a,b,c   Podlutsky, Andrej ^a,c   Sosnowska, Danuta ^a   Tucsek, Zsuzsanna ^a   Toth, Peter ^a   Deak, Ferenc ^a   Gautam, Tripti ^a   Csiszar, Anna ^a,b,d   Sonntag, William E ^a,b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

^c UNIVERSITY OF ALASKA FAIRBANKS   (United States)

^d UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Angiogenesis; Capillary; Endothelial; Inflammation; Oxidative stress; Senescence; Vascular cognitive impairment

Indexed keywords

BETA GALACTOSIDASE; CYTOKINE;

ANGIOGENESIS; ANIMAL; APOPTOSIS; CELL CULTURE; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; DEMENTIA, VASCULAR; DNA DAMAGE; DNA REPAIR; ENDOTHELIUM CELL; GAMMA RADIATION; GENETICS; HIPPOCAMPUS; HUMAN; METABOLISM; MICROVASCULATURE; NERVE CELL; OXIDATIVE STRESS; RADIATION RESPONSE; RAT; SECRETORY PATHWAY; TUMOR SUPPRESSOR GENE; UPREGULATION; VASCULARIZATION; ARTICLE; CAPILLARY.; ENDOTHELIAL; INFLAMMATION; MULTIINFARCT DEMENTIA; RADIATION EXPOSURE; SENESCENCE; VASCULAR COGNITIVE IMPAIRMENT;

ANIMALS; APOPTOSIS; BETA-GALACTOSIDASE; CELL PHYSIOLOGICAL PROCESSES; CELLS, CULTURED; CYTOKINES; DEMENTIA, VASCULAR; DNA DAMAGE; DNA REPAIR; ENDOTHELIAL CELLS; GAMMA RAYS; GENES, P16; HIPPOCAMPUS; HUMANS; MICROVESSELS; NEOVASCULARIZATION, PHYSIOLOGIC; NEURONS; OXIDATIVE STRESS; RATS; SECRETORY PATHWAY; UP-REGULATION;

ANGIOGENESIS; CAPILLARY.; ENDOTHELIAL; INFLAMMATION; OXIDATIVE STRESS; SENESCENCE; VASCULAR COGNITIVE IMPAIRMENT;

EID: 84891616477     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glt057     Document Type: Article

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