Aging-induced dysregulation of Dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 68, Issue 8, 2013, Pages 877-891

  Ungvari, Zoltan ^a,b   Tucsek, Zsuzsanna ^a   Sosnowska, Danuta ^a   Toth, Peter ^a   Gautam, Tripti ^a   Podlutsky, Andrej ^a   Csiszar, Agnes ^a,c   Losonczy, Gyorgy ^d   Valcarcel Ares, M Noa ^a,e   Sonntag, William E ^a,b   Csiszar, Anna ^a,b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

^d SEMMELWEIS UNIVERSITY   (Hungary)

^e Aging and Inflammation Research Lab   (Spain)

Author keywords

Angiogenesis; Capillary density; Cardiovascular aging; Cerebrovascular; Epigenetics; Vascular aging

Indexed keywords

DEAD BOX PROTEIN; DICER1 PROTEIN, RAT; MICRORNA; REACTIVE OXYGEN METABOLITE; RIBONUCLEASE III;

AGING; ANGIOGENESIS; ANIMAL; ARTICLE; BRAIN; BROWN NORWAY RAT; CAPILLARY DENSITY; CARDIOVASCULAR AGING; CELL ADHESION; CELL CULTURE; CELL PROLIFERATION; CEREBROVASCULAR; DOWN REGULATION; DRUG ANTAGONISM; ENDOTHELIUM CELL; EPIGENETICS.; FISCHER 344 RAT; GENE SILENCING; GENETICS; MALE; METABOLISM; MICROVASCULATURE; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; RAT; VASCULAR AGING; VASCULARIZATION;

ANGIOGENESIS; CAPILLARY DENSITY; CARDIOVASCULAR AGING; CEREBROVASCULAR; EPIGENETICS.; VASCULAR AGING;

AGING; ANIMALS; BRAIN; CELL ADHESION; CELL PROLIFERATION; CELLS, CULTURED; DEAD-BOX RNA HELICASES; DOWN-REGULATION; ENDOTHELIAL CELLS; GENE KNOCKDOWN TECHNIQUES; MALE; MICRORNAS; MICROVESSELS; NEOVASCULARIZATION, PHYSIOLOGIC; OXIDATIVE STRESS; RATS; RATS, INBRED BN; RATS, INBRED F344; REACTIVE OXYGEN SPECIES; RIBONUCLEASE III;

EID: 84880569509     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/gls242     Document Type: Article

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