Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 68, Issue 6, 2013, Pages 652-660

  Tucsek, Zsuzsanna ^a   Gautam, Tripti ^a   Sonntag, William E ^a,b   Toth, Peter ^a   Saito, Hiroshi ^c   Salomao, Reinaldo ^d   Szabo, Csaba ^e   Csiszar, Anna ^a,b   Ungvari, Zoltan ^a,b  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^e UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Aging; Bacteremia; Endothelial cells; Microcirculation; Microvascular injury; Sepsis; Septic shock; Septicemia

Indexed keywords

RATTUS NORVEGICUS;

CASPASE 3; CASPASE 8; INTERCELLULAR ADHESION MOLECULE 1; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

AGING; ANIMAL; APOPTOSIS; ARTICLE; BACTEREMIA; BROWN NORWAY RAT; COMPARATIVE STUDY; DISEASE MODEL; ENDOTHELIUM CELL; GENETICS; HUMAN; METABOLISM; MICROCIRCULATION; MICROVASCULAR INJURY; MORTALITY; MULTIPLE ORGAN FAILURE; OXIDATIVE STRESS; PATHOLOGY; RAT; SEPSIS; SEPTIC SHOCK; SEPTIC SHOCK.; SEPTICEMIA; VASCULAR ENDOTHELIUM;

AGING; BACTEREMIA; ENDOTHELIAL CELLS; MICROCIRCULATION; MICROVASCULAR INJURY; SEPSIS; SEPTIC SHOCK.; SEPTICEMIA;

AGING; ANIMALS; APOPTOSIS; BACTEREMIA; CASPASE 3; CASPASE 8; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MULTIPLE ORGAN FAILURE; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; RATS; RATS, INBRED BN; SHOCK, SEPTIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84878309609     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/gls232     Document Type: Article

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