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Volumn , Issue , 2006, Pages 101-120

The normal intestinal mucosa: A state of 'controlled inflammation'

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EID: 84891447998     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/0-387-25808-6_5     Document Type: Chapter
Times cited : (12)

References (145)
  • 1
    • 0033152925 scopus 로고    scopus 로고
    • Regional specialization in the mucosal immune system: Primed cells do not always home along the same track
    • Brandtzaeg P, Farstad IN, Haraldsen G. Regional specialization in the mucosal immune system: Primed cells do not always home along the same track. Immunol Today 1999; 20: 267-77
    • (1999) Immunol Today , vol.20 , pp. 267-277
    • Brandtzaeg, P.1    Farstad, I.N.2    Haraldsen, G.3
  • 4
    • 0028233089 scopus 로고
    • Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer
    • Chang S-K, Dohrman AF, Basbaum CB et al Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer. Gastroenterology 1994; 107: 28-36
    • (1994) Gastroenterology , vol.107 , pp. 28-36
    • Chang, S.-K.1    Dohrman, A.F.2    Basbaum, C.B.3
  • 5
    • 0002912871 scopus 로고    scopus 로고
    • Mucus
    • In: Ogra P.L. Mestecky J Lamm ME Strober W Bienenstock J McGhee Jr. 2nd Edn. San Diego Academic Press
    • Cone RA, Mucus. In: Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors. Mucosal Immunity, 2nd edn. San Diego: Academic Press, 1999: 43-64
    • (1999) Mucosal Immunity , pp. 43-64
    • Cone, R.A.1
  • 6
    • 0000451198 scopus 로고    scopus 로고
    • Structure and function of intestinal mucosal epithelium
    • Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors, 2nd edn. San Diego Academic Press
    • Kato T, Owen RL. Structure and function of intestinal mucosal epithelium. In: Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors. Mucosal Immunity, 2nd edn. San Diego: Academic Press, 1999: 115-32
    • (1999) Mucosal Immunity , pp. 115-132
    • Kato, T.1    Owen, R.L.2
  • 7
    • 0029841664 scopus 로고    scopus 로고
    • M cells in peyer's patches of the intestine
    • Gebert A, Rothkotter HJ, Pabst R. M cells in Peyer's patches of the intestine. Int Rev Cytol 1996; 167: 91-159
    • (1996) Int Rev Cytol , vol.167 , pp. 91-159
    • Gebert, A.1    Rothkotter, H.J.2    Pabst, R.3
  • 8
    • 0032875134 scopus 로고    scopus 로고
    • Innate mechanisms of epithelial host defense: Spothght on intestine
    • Hecht G. Innate mechanisms of epithelial host defense: Spothght on intestine. Am J Physiol 1999; 277: C351-68
    • (1999) Am J Physiol , vol.277
    • Hecht, G.1
  • 9
    • 0033061476 scopus 로고    scopus 로고
    • Cytokine regulation of epithelial permeability and ion transport
    • McKay DM, Baird AW. Cytokine regulation of epithelial permeability and ion transport. Gut 1999; 44: 283-9
    • (1999) Gut , vol.44 , pp. 283-289
    • McKay, D.M.1    Baird, A.W.2
  • 10
    • 0028864991 scopus 로고
    • A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
    • Jung HC, Eckmann L, Yang S-K, et al. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Invest 1995; 95: 55-65
    • (1995) J Clin Invest , vol.95 , pp. 55-65
    • Jung, H.C.1    Eckmann, L.2    Yang, S.-K.3
  • 11
    • 0030747245 scopus 로고    scopus 로고
    • Epithehal cells as sensors for microbial infection
    • Kagnoff MF, Eckmann L. Epithehal cells as sensors for microbial infection. J Clin Invest 1997; 100: 6-10
    • (1997) J Clin Invest , vol.100 , pp. 6-10
    • Kagnoff, M.F.1    Eckmann, L.2
  • 13
    • 0033996191 scopus 로고    scopus 로고
    • Antigen processing and presentation by intestinal epithelial cells-polarity and complexity
    • Hershberg RM, Mayer LF. Antigen processing and presentation by intestinal epithelial cells-polarity and complexity. Immunol Today 2000; 21: 123-8
    • (2000) Immunol Today , vol.21 , pp. 123-128
    • Hershberg, R.M.1    Mayer, L.F.2
  • 14
    • 0023612719 scopus 로고
    • Evidence for function of la molecules on gut epithehal cells in man
    • Mayer L, Shlien R. Evidence for function of la molecules on gut epithehal cells in man. J Exp Med 1987; 166: 1471-83
    • (1987) J Exp Med , vol.166 , pp. 1471-1483
    • Mayer, L.1    Shlien, R.2
  • 15
    • 0025286406 scopus 로고
    • Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: Physiological rearrangements of tight junctions
    • Madara JL. Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: Physiological rearrangements of tight junctions. J Membr Biol 1990; 116: 177-84
    • (1990) J Membr Biol , vol.116 , pp. 177-184
    • Madara, J.L.1
  • 17
    • 0032991667 scopus 로고    scopus 로고
    • Epithelial permeability to proteins in the noninflamed ileum of crohn's disease
    • Soderholm JA, Peterson KM, Olaison G et al. Epithelial permeability to proteins in the noninflamed ileum of crohn's disease? Gastroenterology 1999; 117: 65-72
    • (1999) Gastroenterology , vol.117 , pp. 65-72
    • Soderholm, J.A.1    Peterson, K.M.2    Olaison, G.3
  • 18
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher EC, Picker LJ. Lymphocyte homing and homeostasis. Science 1996; 272: 60-6
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 19
    • 0026686561 scopus 로고
    • T cell differentiation antigens on lymphocytes in the human intestinal lamina propria
    • Schieferdecker HL, Ullrich R, Hirseland H, Zeitz M. T cell differentiation antigens on lymphocytes in the human intestinal lamina propria. J Immunol 1992; 149: 2816-22
    • (1992) J Immunol , vol.149 , pp. 2816-2822
    • Schieferdecker, H.L.1    Ullrich, R.2    Hirseland, H.3    Zeitz, M.4
  • 20
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
    • Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 1994; 76: 301-14
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 21
    • 0031080895 scopus 로고    scopus 로고
    • Cellular environments and apoptosis: Tissue microenvironments control activated T cell death
    • Akbar AN, Salmon M. Cellular environments and apoptosis: Tissue microenvironments control activated T cell death. Immunol Today 1997; 18: 72-6
    • (1997) Immunol Today , vol.18 , pp. 72-76
    • Akbar, A.N.1    Salmon, M.2
  • 22
  • 23
    • 0031978507 scopus 로고    scopus 로고
    • Leukocyte-endothelial interactions: Molecular mechanisms and implications in gastrointestinal disease
    • Panes J, Granger DN. Leukocyte-endothelial interactions: Molecular mechanisms and implications in gastrointestinal disease. Gastroenterology 1998; 114: 1066-90
    • (1998) Gastroenterology , vol.114 , pp. 1066-1090
    • Panes, J.1    Granger, D.N.2
  • 24
    • 0030802049 scopus 로고    scopus 로고
    • Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue
    • Briskin M, Winsor-Hines D, Shyjan A et al. Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. Am J Pathol 1997; 151: 97-110
    • (1997) Am J Pathol , vol.151 , pp. 97-110
    • Briskin, M.1    Winsor-Hines, D.2    Shyjan, A.3
  • 25
    • 0033044063 scopus 로고    scopus 로고
    • Molecules controlling lymphocyte migration to the gut
    • Salmi M, Jalkanen S. Molecules controlling lymphocyte migration to the gut. Gut 1999; 45: 148-53
    • (1999) Gut , vol.45 , pp. 148-153
    • Salmi, M.1    Jalkanen, S.2
  • 26
    • 0032700593 scopus 로고    scopus 로고
    • Through the looking glass: The diverse in vivo activities of chemokines
    • Kunkel SL. Through the looking glass: The diverse in vivo activities of chemokines. J Chn Invest 1999; 104: 1333-4
    • (1999) J Chn Invest , vol.104 , pp. 1333-1334
    • Kunkel, S.L.1
  • 27
    • 0032797272 scopus 로고    scopus 로고
    • Chemokines and cell migration in secondary lymphoid organs
    • Cyster JG. Chemokines and cell migration in secondary lymphoid organs. Science 1999; 286: 2098-102
    • (1999) Science , vol.286 , pp. 2098-2102
    • Cyster, J.G.1
  • 28
    • 0032509889 scopus 로고    scopus 로고
    • Chemokines-chemotactic cytokines that mediate inflammation
    • Luster AD. Chemokines-chemotactic cytokines that mediate inflammation. N Engl J Med 1998; 338: 436-45
    • (1998) N Engl J Med , vol.338 , pp. 436-445
    • Luster, A.D.1
  • 29
    • 0032476678 scopus 로고    scopus 로고
    • Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells
    • Utgaard JO, Jahnsen FL, Bakka A, Brandtzaeg P. Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells. J Exp Med 1998; 188:1751-6
    • (1998) J Exp Med , vol.188 , pp. 1751-1756
    • Utgaard, J.O.1    Jahnsen, F.L.2    Bakka, A.3    Brandtzaeg, P.4
  • 30
    • 0029856309 scopus 로고    scopus 로고
    • Chemokine receptors: Gateways to inflammation and infection
    • Premack BA, Schall TJ. Chemokine receptors: Gateways to inflammation and infection. Nature Med 1996; 2: 1174-8
    • (1996) Nature Med , vol.2 , pp. 1174-1178
    • Premack, B.A.1    Schall, T.J.2
  • 31
    • 0032127167 scopus 로고    scopus 로고
    • Chemokines and Tlymphocytes: More than an attraction
    • Ward SG, Bacon K, Westwick J. Chemokines and Tlymphocytes: More than an attraction. Immunity 1998; 9: 1-11
    • (1998) Immunity , vol.9 , pp. 1-11
    • Ward, S.G.1    Bacon, K.2    Westwick, J.3
  • 32
    • 0033584358 scopus 로고    scopus 로고
    • The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memeory T cells
    • Campbell JJ, Haraldson G, Pan J et al. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memeory T cells. Nature 1999; 400: 776-80
    • (1999) Nature , vol.400 , pp. 776-780
    • Campbell, J.J.1    Haraldson, G.2    Pan, J.3
  • 33
    • 0033554677 scopus 로고    scopus 로고
    • Dual personality of memory T cells
    • Mackay CR. Dual personality of memory T cells. Nature 1999;401:659-60
    • (1999) Nature , vol.401 , pp. 659-660
    • Mackay, C.R.1
  • 34
    • 0033231492 scopus 로고    scopus 로고
    • Human G proteincoupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis
    • Zabel BA, Agace WA, Campbell JJ et al. Human G proteincoupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis. J Exp Med 1999; 190: 1241-55
    • (1999) J Exp Med , vol.190 , pp. 1241-1255
    • Zabel, B.A.1    Agace, W.A.2    Campbell, J.J.3
  • 35
    • 0034327830 scopus 로고    scopus 로고
    • The role of thymusexpressed chemokine and its receptor CCR9 in the regional specialization of the mucosal immune system
    • Papadakis KA, Prehn J, Nelson V et al. The role of thymusexpressed chemokine and its receptor CCR9 in the regional specialization of the mucosal immune system. J Immunol 2000; 165: 5069-76
    • (2000) J Immunol , vol.165 , pp. 5069-5076
    • Papadakis, K.A.1    Prehn, J.2    Nelson, V.3
  • 36
    • 0031963014 scopus 로고    scopus 로고
    • Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (This) and Th2s
    • Bonecchi R, Bianchi G, Bordignon PP et al. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (This) and Th2s. J Exp Med 1998;187: 129-34
    • (1998) J Exp Med , vol.187 , pp. 129-134
    • Bonecchi, R.1    Bianchi, G.2    Bordignon, P.P.3
  • 37
    • 0034001778 scopus 로고    scopus 로고
    • Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemo kines induced by inflammation
    • Agace WW, Roberts Al, Wu L, Greineder C, Ebert EC, Parker CM. Human intestinal lamina propria and intraepithelial lymphocytes express receptors specific for chemo kines induced by inflammation. Eur J Immunol 2000; 30: 819-26
    • (2000) Eur J Immunol , vol.30 , pp. 819-826
    • Agace, W.W.1    Roberts, A.L.2    Wu, L.3    Greineder, C.4    Ebert, E.C.5    Parker, C.M.6
  • 38
    • 0028158113 scopus 로고
    • Aberrant binding of lamina propria lymphocytes to vascular endothelium in inflammatory bowel disease
    • Salmi M, Granfors K, MacDermott RP, Jalkanen S. Aberrant binding of lamina propria lymphocytes to vascular endothelium in inflammatory bowel disease. Gastroenterology 1994; 106: 596-605
    • (1994) Gastroenterology , vol.106 , pp. 596-605
    • Salmi, M.1    Granfors, K.2    MacDermott, R.P.3    Jalkanen, S.4
  • 39
    • 0031989183 scopus 로고    scopus 로고
    • The central role of chemokines (chemotactic cytokines) in the immunopathogenesis of ulcerative colitis and crohn's disease
    • MacDermott RP, Sanderson IR, Reinecker H-C. The central role of chemokines (chemotactic cytokines) in the immunopathogenesis of ulcerative colitis and crohn's disease. Inflamm Bowel Dis 1998; 4: 54-67
    • (1998) Inflamm Bowel Dis , vol.4 , pp. 54-67
    • MacDermott, R.P.1    Sanderson, I.R.2    Reinecker, H.-C.3
  • 40
    • 0028964136 scopus 로고
    • Defensins in granules of phagocytic and phagocytic cells
    • Selsted ME, Oullette AJ. Defensins in granules of phagocytic and phagocytic cells. Trends Cell Biol 1995; 5: 114-19
    • (1995) Trends Cell Biol , vol.5 , pp. 114-119
    • Selsted, M.E.1    Oullette, A.J.2
  • 41
    • 0030731743 scopus 로고    scopus 로고
    • Paneth cells and innate immunity in the crypt microenvironment
    • Ouellette A J. Paneth cells and innate immunity in the crypt microenvironment. Gastroenterology 1997; 113: 1779-84
    • (1997) Gastroenterology , vol.113 , pp. 1779-1784
    • Ouellette A, J.1
  • 42
    • 0002219910 scopus 로고    scopus 로고
    • Defensins and other antimicrobial peptides
    • Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors, 2nd edn. San Diego Academic Press
    • Lehrer RI, Bevins CL, Ganz T. Defensins and other antimicrobial peptides. In: Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors. Mucosal Immunity, 2nd edn. San Diego: Academic Press, 1999: 89-99
    • (1999) Mucosal Immunity , pp. 89-99
    • Lehrer, R.I.1    Bevins, C.L.2    Ganz, T.3
  • 43
    • 0033569408 scopus 로고    scopus 로고
    • P-Defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6
    • Yang D, Chertov O, Bykovskaia SN et al. P-Defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6. Science 1999; 286: 525-8
    • (1999) Science , vol.286 , pp. 525-528
    • Yang, D.1    Chertov, O.2    Bykovskaia, S.N.3
  • 45
    • 0029987839 scopus 로고    scopus 로고
    • The instructive role of innate immunity in the acquired immune response
    • Fearon DT, Locksley RM. The instructive role of innate immunity in the acquired immune response. Science 1996; 272: 50-3
    • (1996) Science , vol.272 , pp. 50-53
    • Fearon, D.T.1    Locksley, R.M.2
  • 47
    • 0031050034 scopus 로고    scopus 로고
    • Innate immunity: Impact on the adaptive immune response
    • Medzhitov R, Janeway CA. Innate immunity: Impact on the adaptive immune response. Curr Opin Immunol 1997; 9: 4-9
    • (1997) Curr Opin Immunol , vol.9 , pp. 4-9
    • Medzhitov, R.1    Janeway, C.A.2
  • 49
    • 0020694836 scopus 로고
    • Heterogeneity of HLA-DR positive histiocytes of human intestinal lamina propria: A combined histochemical and immunological analysis
    • Selby WS, Poulter LW, Hobbs S, Jewell D, Janossy G. Heterogeneity of HLA-DR positive histiocytes of human intestinal lamina propria: A combined histochemical and immunological analysis. J Clin Pathol 1983; 36: 379-84
    • (1983) J Clin Pathol , vol.36 , pp. 379-384
    • Selby, W.S.1    Poulter, L.W.2    Hobbs, S.3    Jewell, D.4    Janossy, G.5
  • 50
    • 0023763043 scopus 로고
    • Macrophage heterogeneity in normal colonic mucosa and in inflammatory bowel disease
    • Allison MC, Cornwall S, Poulter LW, Dhillon AP, Pounder RE. Macrophage heterogeneity in normal colonic mucosa and in inflammatory bowel disease. Gut 1988; 29: 1531-8
    • (1988) Gut , vol.29 , pp. 1531-1538
    • Allison, M.C.1    Cornwall, S.2    Poulter, L.W.3    Dhillon, A.P.4    Pounder, R.E.5
  • 51
    • 0030787528 scopus 로고    scopus 로고
    • Expression of costimulatory molecules B7-1 anf B7-1 in macrophages and granulomas of crohn's disease: Demonstration of cellto-cell contact with T lymphocytes
    • Hara J, Ohtani H, Matsumoto T et al. Expression of costimulatory molecules B7-1 anf B7-1 in macrophages and granulomas of crohn's disease: Demonstration of cellto-cell contact with T lymphocytes. Lab Invest 1997; 77: 175-84
    • (1997) Lab Invest , vol.77 , pp. 175-184
    • Hara, J.1    Ohtani, H.2    Matsumoto, T.3
  • 52
    • 0020676659 scopus 로고
    • Isolation and preliminary characterization of human intestinal macrophages
    • Golder JP, Doe WF. Isolation and preliminary characterization of human intestinal macrophages. Gastroenterology 1983;84:795-802
    • (1983) Gastroenterology , vol.84 , pp. 795-802
    • Golder, J.P.1    Doe, W.F.2
  • 53
    • 0024453024 scopus 로고
    • Respiratory burst activity of intestinal macrophages in normal and inflammatory bowel disease
    • Mahida YR, Wu KC, Jewell DP. Respiratory burst activity of intestinal macrophages in normal and inflammatory bowel disease. Gut 1989; 30: 1362-70
    • (1989) Gut , vol.30 , pp. 1362-1370
    • Mahida, Y.R.1    Wu, K.C.2    Jewell, D.P.3
  • 54
    • 0030995158 scopus 로고    scopus 로고
    • Cytokine profiles differ in newly recruited and resident subsets of mucosal macrophages from inflammatory bowel disease
    • Rugtveit J, Nilsen EM, Bakka A, Carlsen H, Brandtzaeg P, Scott H. Cytokine profiles differ in newly recruited and resident subsets of mucosal macrophages from inflammatory bowel disease. Gastroenterology 1997; 112: 1493-505
    • (1997) Gastroenterology , vol.112 , pp. 1493-1505
    • Rugtveit, J.1    Nilsen, E.M.2    Bakka, A.3    Carlsen, H.4    Brandtzaeg, P.5    Scott, H.6
  • 56
    • 0026748627 scopus 로고
    • Chemiluminescence assay of mucosal reactive oxygen metabolites in inflammatory bowel disease
    • Simmonds NJ, Allen RE, Stevens TRJ et al. Chemiluminescence assay of mucosal reactive oxygen metabolites in inflammatory bowel disease. Gastroenterology 1992; 103: 186-96
    • (1992) Gastroenterology , vol.103 , pp. 186-196
    • Simmonds, N.J.1    Allen, R.E.2    Stevens, T.R.J.3
  • 57
    • 0027283397 scopus 로고
    • Location of superoxide anion generation in human colonic mucosa obtained by biopsy
    • Oshitani N, Kitano A, Okabe H, Nakamura S, Matsumoto T, Kobayashi K. Location of superoxide anion generation in human colonic mucosa obtained by biopsy. Gut 1993; 34: 936-8
    • (1993) Gut , vol.34 , pp. 936-938
    • Oshitani, N.1    Kitano, A.2    Okabe, H.3    Nakamura, S.4    Matsumoto, T.5    Kobayashi, K.6
  • 58
    • 0028883592 scopus 로고
    • Depleted mucosal antioxidant defences in inflammatory bowel disease
    • Buffington GD, Doe WF. Depleted mucosal antioxidant defences in inflammatory bowel disease. Free Radical Biol Med 1995; 19:911-18
    • (1995) Free Radical Biol Med , vol.19 , pp. 911-918
    • Buffington, G.D.1    Doe, W.F.2
  • 59
    • 0032415840 scopus 로고    scopus 로고
    • Expression of nitric oxide synthases and formation of nitrotyrosine and reactive oxygen species in inflammatory bowel disease
    • Dijkstra G, Moshage H, VanDulleman HM et al. Expression of nitric oxide synthases and formation of nitrotyrosine and reactive oxygen species in inflammatory bowel disease. J Pathol 1998; 186:416-21
    • (1998) J Pathol , vol.186 , pp. 416-421
    • Dijkstra, G.1    Moshage, H.2    VanDulleman, H.M.3
  • 60
    • 0029816226 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease
    • Singer II, Kawka DW, Scott S et al. Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease. Gastroenterology 1996; 111: 871-85
    • (1996) Gastroenterology , vol.111 , pp. 871-885
    • Singer, I.I.1    Kawka, D.W.2    Scott, S.3
  • 61
    • 0033868029 scopus 로고    scopus 로고
    • Nitric oxide in mucosal defense: A little goes a long way
    • Wallace JL, Miller MJS. Nitric oxide in mucosal defense: A little goes a long way. Gastroenterology 2000; 119: 512-20
    • (2000) Gastroenterology , vol.119 , pp. 512-520
    • Wallace, J.L.1    Miller, M.J.S.2
  • 62
    • 0031921084 scopus 로고    scopus 로고
    • The role of complement and complement receptors in induction and regulation of immunity
    • Carroll MC. The role of complement and complement receptors in induction and regulation of immunity. Annu Rev Immunol 1998; 16: 545-68
    • (1998) Annu Rev Immunol , vol.16 , pp. 545-568
    • Carroll, M.C.1
  • 63
    • 0024412083 scopus 로고
    • Persistent complement activation in submucosal vessels of active inflammatory bowel disease: Immunohistochemical evidence
    • Halstensen TS, Mollnes TE, Brandtzaeg P. Persistent complement activation in submucosal vessels of active inflammatory bowel disease: Immunohistochemical evidence. Gastroenterology 1989; 97: 10-19
    • (1989) Gastroenterology , vol.97 , pp. 10-19
    • Halstensen, T.S.1    Mollnes, T.E.2    Brandtzaeg, P.3
  • 64
    • 0025239287 scopus 로고
    • Enhanced local production of complement components in the small intestines of patients with crohn's disease
    • Ahrenstedt O, Knutson L, Nilsson B, Nilsson-Ekdahl K, Odlind B, Hallgren R. Enhanced local production of complement components in the small intestines of patients with crohn's disease. N Engl J Med 1990; 322: 1345-9
    • (1990) N Engl J Med , vol.322 , pp. 1345-1349
    • Ahrenstedt, O.1    Knutson, L.2    Nilsson, B.3    Nilsson-Ekdahl, K.4    Odlind, B.5    Hallgren, R.6
  • 65
    • 0001743458 scopus 로고    scopus 로고
    • Biological activities of iga
    • Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors, 2nd edn. San Diego Academic Press
    • Russell MW, Kilian M, Lamm ME. Biological activities of IgA. In: Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors. Mucosal Immunology, 2nd edn. San Diego: Academic Press, 1999
    • (1999) Mucosal Immunology
    • Russell, M.W.1    Kilian, M.2    Lamm, M.E.3
  • 68
    • 0015515012 scopus 로고
    • Intestinal uptake of macromolecules: Effect of oral immunization
    • Walker WA, Issclbacher KJ, Bloch KJ. Intestinal uptake of macromolecules: Effect of oral immunization. Science 1972; 177:608-10
    • (1972) Science , vol.177 , pp. 608-610
    • Walker, W.A.1    Issclbacher, K.J.2    Bloch, K.J.3
  • 69
    • 0028334420 scopus 로고
    • All forms of human IgA antibodies bound to antigen interfere with complement (C3) fixation induced by IgG or by antigen alone
    • Nikolova EB, Tomana M, Russell MW. All forms of human IgA antibodies bound to antigen interfere with complement (C3) fixation induced by IgG or by antigen alone. Scand J Immunol 1994; 39: 275-80
    • (1994) Scand J Immunol , vol.39 , pp. 275-280
    • Nikolova, E.B.1    Tomana, M.2    Russell, M.W.3
  • 70
    • 0026604788 scopus 로고
    • Oligoclonality of human intestinal intraepithelial T cells
    • VanKerckhove C, Russell GJ, Deusch K et al. Oligoclonality of human intestinal intraepithelial T cells. J Exp Med 1992; 175: 57-63
    • (1992) J Exp Med , vol.175 , pp. 57-63
    • VanKerckhove, C.1    Russell, G.J.2    Deusch, K.3
  • 73
    • 0024331733 scopus 로고
    • Proliferative responses of human intraepithelial lymphocytes to various T cell stimuli
    • Ebert EC. Proliferative responses of human intraepithelial lymphocytes to various T cell stimuli. Gastroenterology 1989; 97: 1372-81
    • (1989) Gastroenterology , vol.97 , pp. 1372-1381
    • Ebert, E.C.1
  • 74
    • 0021908939 scopus 로고
    • Intraepithelial lymphocytes of human gut: Isolation, characterization and study of natural killer activity
    • Cerf-Bensussan N, Guy-Grand D, Griscelli C. Intraepithelial lymphocytes of human gut: Isolation, characterization and study of natural killer activity. Gut 1985; 26: 81-8
    • (1985) Gut , vol.26 , pp. 81-88
    • Cerf-Bensussan, N.1    Guy-Grand, D.2    Griscelli, C.3
  • 75
    • 0026571296 scopus 로고
    • Spontaneous cytotoxicity of human intrapithelial lymphocytes against epithelial cell tumors
    • Taunk J, Roberts Al, Ebert EC. Spontaneous cytotoxicity of human intrapithelial lymphocytes against epithelial cell tumors. Gastroenterology 1992; 102: 69-75
    • (1992) Gastroenterology , vol.102 , pp. 69-75
    • Taunk, J.1    Roberts, A.L.2    Ebert, E.C.3
  • 76
    • 0029080796 scopus 로고    scopus 로고
    • Human intestinal intraepithelial lymphocytes have potent chemotactic activity
    • Ebert EC. Human intestinal intraepithelial lymphocytes have potent chemotactic activity. Gastroenterology 1996; 109: 1154-9
    • (1996) Gastroenterology , vol.109 , pp. 1154-1159
    • Ebert, E.C.1
  • 77
    • 0023024787 scopus 로고
    • Phenotypic analysis of lamina propria lymphocytes predominance of helper-inducer and cytolytic t cell phenotype and deficiency of suppressor-inducer phenotype in crohn's disease and control patients
    • James SP, Fiocchi C, Graeff AS, Strober W. Phenotypic analysis of lamina propria lymphocytes. Predominance of helper-inducer and cytolytic T cell phenotype and deficiency of suppressor-inducer phenotype in crohn's disease and control patients. Gastroenterology 1986; 91: 1483-9
    • (1986) Gastroenterology , vol.91 , pp. 1483-1489
    • James, S.P.1    Fiocchi, C.2    Graeff, A.S.3    Strober, W.4
  • 78
    • 0032920934 scopus 로고    scopus 로고
    • Evidence of T cell receptor p-chain patterns in inflammatory and noninflammatory bowel disease states
    • Saubermann LJ, Probert CSJ, Christ AD et al. Evidence of T cell receptor p-chain patterns in inflammatory and noninflammatory bowel disease states. Am J Physiol 1999; 276: G613-21
    • (1999) Am J Physiol , vol.276
    • Saubermann, L.J.1    Probert, C.S.J.2    Christ, A.D.3
  • 79
    • 0023219626 scopus 로고
    • Activation of peripheral blood and intestinal lamina propria lymphocytes in crohn's disease in vivo state of activation and in vitro response to stimulation as defined by the expression of early activation antigens
    • Pallone F, Fais S, Squarcia O, Biancone L, Pozzilli P, Boirivant M. Activation of peripheral blood and intestinal lamina propria lymphocytes in crohn's disease. In vivo state of activation and in vitro response to stimulation as defined by the expression of early activation antigens. Gut 1987; 28: 745-53
    • (1987) Gut , vol.28 , pp. 745-753
    • Pallone, F.1    Fais, S.2    Squarcia, O.3    Biancone, L.4    Pozzilli, P.5    Boirivant, M.6
  • 81
    • 0030050848 scopus 로고    scopus 로고
    • Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes
    • DeMaria R, Boirivant M, Cifone MG et al. Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. J Clin Invest 1996; 97: 316-22
    • (1996) J Clin Invest , vol.97 , pp. 316-322
    • DeMaria, R.1    Boirivant, M.2    Cifone, M.G.3
  • 82
    • 0029847082 scopus 로고    scopus 로고
    • Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis
    • Boirivant M, Pica R, DeMaria R, Testi R, Paflone F, Strober W. Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis. J Chn Invest 1996; 98: 2616-22
    • (1996) J Chn Invest , vol.98 , pp. 2616-2622
    • Boirivant, M.1    Pica, R.2    DeMaria, R.3    Testi, R.4    Paflone, F.5    Strober, W.6
  • 83
    • 0033565302 scopus 로고    scopus 로고
    • Resistance of crohn's disease T cells to multiple apoptotic stimuli is associated with a Bcl-2/Bax mucosal imbalance
    • Ina K, Itoh J, Fukushima K et al. Resistance of crohn's disease T cells to multiple apoptotic stimuli is associated with a Bcl-2/Bax mucosal imbalance. J Immunol 1999; 163: 1081-90
    • (1999) J Immunol , vol.163 , pp. 1081-1090
    • Ina, K.1    Itoh, J.2    Fukushima, K.3
  • 84
    • 0033011679 scopus 로고    scopus 로고
    • Lamina propria T cells in crohn's disease and other gastrointestinal inflammation show defective CD2 pathway-induced apoptosis
    • Boirivant M, Marini M, DiFelice G et al. Lamina propria T cells in crohn's disease and other gastrointestinal inflammation show defective CD2 pathway-induced apoptosis. Gastroenterology 1999; 116: 557-65
    • (1999) Gastroenterology , vol.116 , pp. 557-565
    • Boirivant, M.1    Marini, M.2    DiFelice, G.3
  • 85
    • 0019489932 scopus 로고
    • Studies on isolated gut mucosal lymphocytes in inflammatory bowel disease detection of activated t cells and enhanced proliferation to staphylococcus areus and lipopolysaccharides
    • Fiocchi C, Battisto JR, Farmer RG. Studies on isolated gut mucosal lymphocytes in inflammatory bowel disease. Detection of activated T cells and enhanced proliferation to Staphylococcus areus and lipopolysaccharides. Dig Dis Sci 1981;26:728-36
    • (1981) Dig Dis Sci , vol.26 , pp. 728-736
    • Fiocchi, C.1    Battisto, J.R.2    Farmer, R.G.3
  • 86
    • 0018920045 scopus 로고
    • Human intestinal mononuclear cells I Investigation of antibody-dependent, Lectin-induced, and spontaneous cell-mediated cytotoxic capabilities
    • MacDermott RP, Franklin GO, Jenkins KM, Kodner IJ, Nash GS, Weinrieb IJ. Human intestinal mononuclear cells. I. Investigation of antibody-dependent, Lectin-induced, and spontaneous cell-mediated cytotoxic capabilities. Gastroenterology 1980; 78: 47-56
    • (1980) Gastroenterology , vol.78 , pp. 47-56
    • MacDermott, R.P.1    Franklin, G.O.2    Jenkins, K.M.3    Kodner, I.J.4    Nash, G.S.5    Weinrieb, I.J.6
  • 87
    • 0021919898 scopus 로고
    • Human intestinal mucosal mononuclear cells exhibit lymphokine-Activated killer ceU activity
    • Fiocchi C, Tubbs RR, Youngman KR. Human intestinal mucosal mononuclear cells exhibit lymphokine-Activated killer ceU activity. Gastroenterology 1985; 88: 625-37
    • (1985) Gastroenterology , vol.88 , pp. 625-637
    • Fiocchi, C.1    Tubbs, R.R.2    Youngman, K.R.3
  • 89
    • 0019445743 scopus 로고
    • Human intestinal mononuclear cells II Demonstration of a naturally occurring subclass of T cells which respond in the allogeneic mixed lymphocyte reaction but do not effect cell-mediated lympholysis
    • MacDermott RP, Bragdon MJ, Jenkins KM, Franklin GO, Shedlofsky S, Kodner IJ. Human intestinal mononuclear cells. II. Demonstration of a naturally occurring subclass of T cells which respond in the allogeneic mixed lymphocyte reaction but do not effect cell-mediated lympholysis. Gastroenterology 1981; 80: 748-57
    • (1981) Gastroenterology , vol.80 , pp. 748-757
    • MacDermott, R.P.1    Bragdon, M.J.2    Jenkins, K.M.3    Franklin, G.O.4    Shedlofsky, S.5    Kodner, I.J.6
  • 90
    • 1842264266 scopus 로고
    • Cytokines
    • Targan S.R Shanahan F editors. From Bench to Bedside. Baltimore: Williams & Wilkins
    • Fiocchi C. Cytokines. In: Targan SR, Shanahan F, editors. Inflammatory Bowel Disease. From Bench to Bedside. Baltimore: Williams & Wilkins, 1994: 106-22
    • (1994) Inflammatory Bowel Disease , pp. 106-122
    • Fiocchi, C.1
  • 91
    • 0030209985 scopus 로고    scopus 로고
    • Disparate CD4+ lamina propria lymphokine secretion profiles in inflammatory bowel disease
    • Fuss IJ, Neurath M, Boirivant M et al. Disparate CD4+ lamina propria lymphokine secretion profiles in inflammatory bowel disease. J Immunol 1996; 157: 1261-70
    • (1996) J Immunol , vol.157 , pp. 1261-1270
    • Fuss, I.J.1    Neurath, M.2    Boirivant, M.3
  • 92
    • 0025027664 scopus 로고
    • Differential responsiveness to CD3-Ti vs CD2-dependent activation of human intestinal lymphocytes
    • Pirzer UC, Schurmann G, Post S, Betzler M, Meuer SC. Differential responsiveness to CD3-Ti vs CD2-dependent activation of human intestinal lymphocytes. Eur J Immunol 1990; 20: 2339-42
    • (1990) Eur J Immunol , vol.20 , pp. 2339-2342
    • Pirzer, U.C.1    Schurmann, G.2    Post, S.3    Betzler, M.4    Meuer, S.C.5
  • 93
    • 0025931643 scopus 로고
    • Activation and signaling status of human lamina propria T lymphocytes
    • Qiao L, Schurmann G, Betzler M, Meuer SC. Activation and signaling status of human lamina propria T lymphocytes. Gastroenterology 1991; 101: 1529-36
    • (1991) Gastroenterology , vol.101 , pp. 1529-1536
    • Qiao, L.1    Schurmann, G.2    Betzler, M.3    Meuer, S.C.4
  • 94
    • 0025939256 scopus 로고
    • Downregulation of protein kinase C activation in human lamina propria T lymphocytes: Influence of intestinal mucosa on T cell reactivity
    • Qiao L, Schurmann G, Betzler M, Meuer SC. Downregulation of protein kinase C activation in human lamina propria T lymphocytes: Influence of intestinal mucosa on T cell reactivity. Eur J Immunol 1991; 21: 2385-9
    • (1991) Eur J Immunol , vol.21 , pp. 2385-2389
    • Qiao, L.1    Schurmann, G.2    Betzler, M.3    Meuer, S.C.4
  • 97
    • 0029033344 scopus 로고
    • CD2 and the regulation of T cell anergy
    • Bell GM, Imboden JB. CD2 and the regulation of T cell anergy. J Immunol 1995; 154: 2805-6
    • (1995) J Immunol , vol.154 , pp. 2805-2806
    • Bell, G.M.1    Imboden, J.B.2
  • 98
    • 0030056870 scopus 로고    scopus 로고
    • Anergy as a mechanims of peripheral T cell tolerance
    • Quill H. Anergy as a mechanims of peripheral T cell tolerance. J Immunol 1996; 156: 1325-7
    • (1996) J Immunol , vol.156 , pp. 1325-1327
    • Quill, H.1
  • 99
    • 0023845341 scopus 로고
    • Mucosal t cells provide helper function but do not proliferate when stimulated by specific antigen in lymphogranuloma venereum proctitis in nonhuman primates
    • Zeitz M, Quinn TC, Graeff AS, James SP. Mucosal T cells provide helper function but do not proliferate when stimulated by specific antigen in lymphogranuloma venereum proctitis in nonhuman primates. Gastroenterology 1988; 94: 353-66
    • (1988) Gastroenterology , vol.94 , pp. 353-366
    • Zeitz, M.1    Quinn, T.C.2    Graeff, A.S.3    James, S.P.4
  • 100
    • 0001237853 scopus 로고    scopus 로고
    • Mucosal immune responses
    • Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors,2nd edn. San Diego Academic Press
    • McGhee JR, Lamm ME, Strober W. Mucosal immune responses. In: Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors. Mucosal Immunity,2nd edn. San Diego: Academic Press, 1999: 485-506
    • (1999) Mucosal Immunity , pp. 485-506
    • McGhee, J.R.1    Lamm, M.E.2    Strober, W.3
  • 101
    • 0032502801 scopus 로고    scopus 로고
    • Homeostasis and self-Tolerance in the immune system: Turning lymphocytes off
    • VanParijs L, Abbas AK. Homeostasis and self-Tolerance in the immune system: Turning lymphocytes off. Science 1998; 280: 243-8
    • (1998) Science , vol.280 , pp. 243-248
    • VanParijs, L.1    Abbas, A.K.2
  • 102
    • 0031091743 scopus 로고    scopus 로고
    • Is CTLA-4 a master switch for peripheral T cell tolerance
    • Bluestone JA. Is CTLA-4 a master switch for peripheral T cell tolerance? J Immunol 1997; 158: 1989-93
    • (1997) J Immunol , vol.158 , pp. 1989-1993
    • Bluestone, J.A.1
  • 103
    • 0032190089 scopus 로고    scopus 로고
    • T cell anergy and altered T cell receptor signaling: Effects on autoimmune disease
    • Salojin KV, Zhang J, Madrenas J, Delovitch XL. T cell anergy and altered T cell receptor signaling: Effects on autoimmune disease. Immunol Today 1998; 19: 468-73
    • (1998) Immunol Today , vol.19 , pp. 468-473
    • Salojin, K.V.1    Zhang, J.2    Madrenas, J.3    Delovitch, X.L.4
  • 104
    • 0029851224 scopus 로고    scopus 로고
    • Costimulatory B7 molecules in the pathogenesis of infections and autoimmune diseases
    • Reiser H, Stadecker MJ. Costimulatory B7 molecules in the pathogenesis of infections and autoimmune diseases. N Engl J Med 1996; 335: 1369-77
    • (1996) N Engl J Med , vol.335 , pp. 1369-1377
    • Reiser, H.1    Stadecker, M.J.2
  • 105
    • 0033407382 scopus 로고    scopus 로고
    • Antigen presentation by parenchymal cells: A route to peripheral tolerance
    • Marelli-Berg FM, Lechler RI. Antigen presentation by parenchymal cells: A route to peripheral tolerance? Immunol Rev 1999; 172:297-314
    • (1999) Immunol Rev , vol.172 , pp. 297-314
    • Marelli Berg, F.M.1    Lechler, R.I.2
  • 106
    • 43949165663 scopus 로고
    • Activation-induced cell death (apoptosis) of mature peripheral blood T lymphocytes
    • Kabelitz D, Pohl T, Pechhold K. Activation-induced cell death (apoptosis) of mature peripheral blood T lymphocytes. Immunol Today 1993; 14: 338-9
    • (1993) Immunol Today , vol.14 , pp. 338-339
    • Kabelitz, D.1    Pohl, T.2    Pechhold, K.3
  • 107
    • 0028802845 scopus 로고
    • Fas and fasl in the homeostatic regulation of immune responses
    • Lynch DH, Ramsdell F, Alderson MR. Fas and FasL in the homeostatic regulation of immune responses. Immunol Today 1995;16:569-74
    • (1995) Immunol Today , vol.16 , pp. 569-574
    • Lynch, D.H.1    Ramsdell, F.2    Alderson, M.R.3
  • 108
    • 0034084162 scopus 로고    scopus 로고
    • Regulatory T cells in autoimmunity
    • Shevach EA. Regulatory T cells in autoimmunity. Annu Rev Immunol 2000; 18:423-49
    • (2000) Annu Rev Immunol , vol.18 , pp. 423-449
    • Shevach, E.A.1
  • 109
    • 0031966706 scopus 로고    scopus 로고
    • Immune responses to dietary antigens: Oral tolerance
    • Strobel S, Mowat AM. Immune responses to dietary antigens: Oral tolerance. Immunol Today 1998; 19: 173-81
    • (1998) Immunol Today , vol.19 , pp. 173-181
    • Strobel, S.1    Mowat, A.M.2
  • 110
    • 0002012185 scopus 로고    scopus 로고
    • Cytokines, chemokines, growth factors, eicosanoids and other bioactive molecules in IBD
    • In: Kirsner JB, editor. Philadelphia: WB. Saunders
    • Podolsky DK, Fiocchi C. Cytokines, chemokines, growth factors, eicosanoids and other bioactive molecules in IBD. In: Kirsner JB, editor. Inflammatory Bowel Disease. Philadelphia: WB. Saunders, 1999: 191-207
    • (1999) Inflammatory Bowel Disease , pp. 191-207
    • Podolsky, D.K.1    Fiocchi, C.2
  • 111
    • 0034041692 scopus 로고    scopus 로고
    • Normal immune responses to ingested foods
    • Husby S. Normal immune responses to ingested foods. J Pediatr Gastroenterol Nutr 2000; 30: SI3-19
    • (2000) J Pediatr Gastroenterol Nutr , vol.30
    • Husby, S.1
  • 112
    • 0032400869 scopus 로고    scopus 로고
    • Mucosal immunity of the gastrointestinal tract and oral tolerance
    • Simecka JW. Mucosal immunity of the gastrointestinal tract and oral tolerance. Adv Drug Deliv Rev 1998; 34: 235-59
    • (1998) Adv Drug Deliv Rev , vol.34 , pp. 235-259
    • Simecka, J.W.1
  • 113
    • 0026042008 scopus 로고
    • Oral tolerance in experimental autoimmune encephalomyelitis III Evidence for clonal anergy
    • Whitaker CC, Gienapp IE, Orosz CG, Bitar D. Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy. J Immunol 1991; 147: 2155-63
    • (1991) J Immunol , vol.147 , pp. 2155-2163
    • Whitaker, C.C.1    Gienapp, I.E.2    Orosz, C.G.3    Bitar, D.4
  • 115
    • 0029659056 scopus 로고    scopus 로고
    • The physiological role of regulatory T cells in the prevention of autoimmunity: The function of the thymus in the generation of the regulatory T cell subset
    • Saoudi A, Seddon B, Heath V, Fowell D, Mason D. The physiological role of regulatory T cells in the prevention of autoimmunity: The function of the thymus in the generation of the regulatory T cell subset. Immunol Rev 1996; 149: 195-216
    • (1996) Immunol Rev , vol.149 , pp. 195-216
    • Saoudi, A.1    Seddon, B.2    Heath, V.3    Fowell, D.4    Mason, D.5
  • 116
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen Y, Kuchroo VK, Inobe J-I, Hafler DA, Weiner HL. Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis. Science 1994; 265: 1237-40
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.-I.3    Hafler, D.A.4    Weiner, H.L.5
  • 117
    • 0030704726 scopus 로고    scopus 로고
    • A CD4'-T ceU subset inhibits antigen-specific T cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M et al. A CD4'-T ceU subset inhibits antigen-specific T cell responses and prevents colitis. Nature 1997; 389: 737-42
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3
  • 118
    • 0031569530 scopus 로고    scopus 로고
    • CD4-T cell down-regulation in human intestinal mucosa. Evidence for intestinal tolerance to luminal bacterial antigens
    • Khoo UY, Proctor IE, Macpherson AJS. CD4-T cell down-regulation in human intestinal mucosa. Evidence for intestinal tolerance to luminal bacterial antigens. J Immunol 1997; 158:3626-34
    • (1997) J Immunol , vol.158 , pp. 3626-3634
    • Khoo, U.Y.1    Proctor, I.E.2    Macpherson, A.J.S.3
  • 119
    • 0032536827 scopus 로고    scopus 로고
    • CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: Increased T helper cell type 1 response and ability to transfer disease
    • Cong BY, Brandwein SL, McCabe RP et al CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: Increased T helper cell type 1 response and ability to transfer disease. J Exp Med 1998; 187: 855-64
    • (1998) J Exp Med , vol.187 , pp. 855-864
    • Cong, B.Y.1    Brandwein, S.L.2    McCabe, R.P.3
  • 120
    • 0034679567 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyteassociated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation
    • Read S, Malmstrom V, Powrie F. Cytotoxic T lymphocyteassociated antigen 4 plays an essential role in the function of CD25+CD4+ regulatory cells that control intestinal inflammation. J Exp Med 2000; 192: 295-302
    • (2000) J Exp Med , vol.192 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 121
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 1999; 190:995-1003
    • (1999) J Exp Med , vol.190 , pp. 995-1003
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 122
    • 0034131557 scopus 로고    scopus 로고
    • Abrogation of tgf(3 signaling in t cells leads to spontaneous t cell differentiation and autoimmune disease
    • Gorelik L, Flavell RA. Abrogation of TGF(3 signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity 2000; 12: 171-81
    • (2000) Immunity , vol.12 , pp. 171-181
    • Gorelik, L.1    Flavell, R.A.2
  • 123
    • 0030847054 scopus 로고    scopus 로고
    • Oral tolerance: Immune mechanisms and treatment of autoimmune diseases
    • Weiner HL. Oral tolerance: Immune mechanisms and treatment of autoimmune diseases. Immunol Today 1997; 18: 335-43
    • (1997) Immunol Today , vol.18 , pp. 335-343
    • Weiner, H.L.1
  • 124
    • 0005000198 scopus 로고    scopus 로고
    • Food allergies
    • Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors, 2nd edn. San Diego Academic Press
    • Crowe SE. Food allergies. In: Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR, editors. Mucosal Immunity, 2nd edn. San Diego: Academic Press, 1999: 1129-39
    • (1999) Mucosal Immunity , pp. 1129-1139
    • Crowe, S.E.1
  • 125
    • 84891398360 scopus 로고
    • The immunological resources of the large bowel
    • In: Kirsner JB, Shorter RG, editors Baltimore: Williams & Wilkins
    • Fiocchi C. The immunological resources of the large bowel. In: Kirsner JB, Shorter RG, editors. Diseases of the Colon, Rectum, and Anal Canal. Baltimore: Williams & Wilkins, 1988:95-117
    • (1988) Diseases of the Colon, Rectum, and Anal Canal , pp. 95-117
    • Fiocchi, C.1
  • 126
    • 84982189058 scopus 로고
    • A review: Probiotics in man and animals
    • Fuller R. A review: Probiotics in man and animals. J Appl Bacteriol 1989; 66: 365-78
    • (1989) J Appl Bacteriol , vol.66 , pp. 365-378
    • Fuller, R.1
  • 127
    • 0033066028 scopus 로고    scopus 로고
    • Cow's milk and type I diabetes: The gut immune system deserves attention
    • Kolb H, Pozzilli P. Cow's milk and type I diabetes: The gut immune system deserves attention. Immunol Today 1999; 20: 108-110
    • (1999) Immunol Today , vol.20 , pp. 108-110
    • Kolb, H.1    Pozzilli, P.2
  • 129
    • 0030752712 scopus 로고    scopus 로고
    • Phylogenetic placement of community members in human colonic biota
    • Wilson KH, Ikeda JS, Blitchington RB. Phylogenetic placement of community members in human colonic biota. Clin Infect Dis 1997; 25: SI 14-16
    • (1997) Clin Infect Dis , vol.25
    • Wilson, K.H.1    Ikeda, J.S.2    Blitchington, R.B.3
  • 130
    • 0001968001 scopus 로고    scopus 로고
    • Stimulation of immunity by probiotics
    • Fuller R, editor. Applications and Practical Aspects. London Chapman & Hall
    • Famularo G, Moretti S, Marcellini S, DeSimone C. Stimulation of immunity by probiotics. In: Fuller R, editor. Probiotics 2. Applications and Practical Aspects. London: Chapman & Hall, 1997: 133-61
    • (1997) Probiotics , vol.2 , pp. 133-161
    • Famularo, G.1    Moretti, S.2    Marcellini, S.3    DeSimone, C.4
  • 132
    • 9544226450 scopus 로고    scopus 로고
    • Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human p2 microglobulin transgenic rats
    • Rath HC, Herfarth HH, Ikeda JS et al. Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human p2 microglobulin transgenic rats. J Clin Invest 1996; 98: 945-53
    • (1996) J Clin Invest , vol.98 , pp. 945-953
    • Rath, H.C.1    Herfarth, H.H.2    Ikeda, J.S.3
  • 134
    • 0032412057 scopus 로고    scopus 로고
    • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
    • Sellon RK, Tonkonogy S, Schultz M et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 1998; 66: 5224-31
    • (1998) Infect Immun , vol.66 , pp. 5224-5231
    • Sellon, R.K.1    Tonkonogy, S.2    Schultz, M.3
  • 135
    • 0025887076 scopus 로고
    • Effect of faecal stream diversion on recurrence of crohn's disease in the neoterminal ileum
    • Rutgeerts P, Geboes K, Peeters M et al. Effect of faecal stream diversion on recurrence of crohn's disease in the neoterminal ileum. Lancet 1991; 2: 771-4
    • (1991) Lancet , vol.2 , pp. 771-774
    • Rutgeerts, P.1    Geboes, K.2    Peeters, M.3
  • 136
    • 0031915148 scopus 로고    scopus 로고
    • Early lesions caused by infusion of intestinal contents in excluded ileum of crohn's disease
    • D'Haens G, Geboes K, Peeters M, Baert F, Penninckx F, Rutgeerts P. Early lesions caused by infusion of intestinal contents in excluded ileum of crohn's disease. Gastroenterology 1998; 114:262-7
    • (1998) Gastroenterology , vol.114 , pp. 262-267
    • D'Haens, G.1    Geboes, K.2    Peeters, M.3    Baert, F.4    Penninckx, F.5    Rutgeerts, P.6
  • 139
    • 0031763109 scopus 로고    scopus 로고
    • Long-Term treatment of ulcerative colitis with ciprofloxacin: A prospective, double-blind, placebo-controlled study
    • Turunen UM, Farkkila MA, Hakala K et al. Long-Term treatment of ulcerative colitis with ciprofloxacin: A prospective, double-blind, placebo-controlled study. Gastroenterology 1998; 115: 1072-8
    • (1998) Gastroenterology , vol.115 , pp. 1072-1078
    • Turunen, U.M.1    Farkkila, M.A.2    Hakala, K.3
  • 140
    • 0033860601 scopus 로고    scopus 로고
    • Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: A double-blind, placebo-controlled trial
    • Gionchelti P, Rizzello F, Venturi A et al. Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: A double-blind, placebo-controlled trial. Gastroenterology 2000; 119: 305-9
    • (2000) Gastroenterology , vol.119 , pp. 305-309
    • Gionchelti, P.1    Rizzello, F.2    Venturi, A.3
  • 141
    • 0029586031 scopus 로고
    • Tolerance exists towards resident intestinal flora but it is broken in active inflammatory bowel disease (IBD
    • Duchmann R, Kaiser I, Hermann E, Mayet W, Ewe K, Meyer Zum Buschenfelde KH. Tolerance exists towards resident intestinal flora but it is broken in active inflammatory bowel disease (IBD). Clin Exp Immunol 1995; 102: 448-55
    • (1995) Clin Exp Immunol , vol.102 , pp. 448-455
    • Duchmann, R.1    Kaiser, I.2    Hermann, E.3    Mayet, W.4    Ewe, K.5    Meyer Zum Buschenfelde, K.H.6
  • 142
    • 0029993786 scopus 로고    scopus 로고
    • Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interlukin-10 or antibodies to interleukin-12
    • Duchmann R, Schmitt E, Knolle P, Meyer Zum Buschenfelde KH, Neurath M. Tolerance towards resident intestinal flora in mice is abrogated in experimental colitis and restored by treatment with interlukin-10 or antibodies to interleukin-12. Eur J Immunol 1996; 26: 934-8
    • (1996) Eur J Immunol , vol.26 , pp. 934-938
    • Duchmann, R.1    Schmitt, E.2    Knolle, P.3    Meyer Zum Buschenfelde, K.H.4    Neurath, M.5
  • 144
    • 0033083260 scopus 로고    scopus 로고
    • Clonal expansion of CD4-T cells in TCR a-chain-deficient mice by gut-derived antigens
    • Takahashi I, Lijima H, Katashima R, Itakura M, Kiyono H. Clonal expansion of CD4-T cells in TCR a-chain-deficient mice by gut-derived antigens. J Immunol 1999; 162: 1843-50
    • (1999) J Immunol , vol.162 , pp. 1843-1850
    • Takahashi, I.1    Lijima, H.2    Katashima, R.3    Itakura, M.4    Kiyono, H.5
  • 145
    • 0033558364 scopus 로고    scopus 로고
    • Chronic intestinal inflammation in STAT-4 transgenic mice: Characterization of disease and adoptive transfer by TNF-plus IFN-yproducing CD4+ T cells that respond to bacterial antigens
    • Wirtz S, Finotto S, Kanzler S et al. Chronic intestinal inflammation in STAT-4 transgenic mice: Characterization of disease and adoptive transfer by TNF-plus IFN-yproducing CD4+ T cells that respond to bacterial antigens. J Immunol 1999; 162: 1884-8
    • (1999) J Immunol , vol.162 , pp. 1884-1888
    • Wirtz, S.1    Finotto, S.2    Kanzler, S.3


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