Genomic mutation rates that neutralize adaptive evolution and natural selection

Journal of the Royal Society Interface

Volumn 10, Issue 85, 2013, Pages

  Gerrish, Philip J ^a,b   Colato, Alexandre ^c   Sniegowski, Paul D ^d  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

^c FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Beneficial mutations; Error threshold; Fisher's fundamental theorem; Mutagenesis; Population genetics

Indexed keywords

BIOPHYSICS; BIOTECHNOLOGY; MUTAGENESIS;

ADAPTIVE EVOLUTION; BENEFICIAL MUTATIONS; ERROR THRESHOLD; FUNDAMENTAL THEOREMS; GENOMIC MUTATION; MATHEMATICAL EXPRESSIONS; NATURAL SELECTION; POPULATION GENETICS;

BIOLOGY;

ADAPTATION; ADAPTIVE EVOLUTION; ARTICLE; ENVIRONMENT; EPISTASIS; EVOLUTION; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MATING; MUTATION RATE; NATURAL SELECTION; NONHUMAN; PHASE TRANSITION; POINT MUTATION; POPULATION SIZE; THEORY; BIOLOGICAL MODEL; GENETIC SELECTION; GENOME; GENOTYPE ENVIRONMENT INTERACTION; MOLECULAR EVOLUTION; MUTATION; PHYSIOLOGY; BENEFICIAL MUTATIONS; ERROR THRESHOLD; FISHER'S FUNDAMENTAL THEOREM; MUTAGENESIS; POPULATION GENETICS;

EVOLUTION, MOLECULAR; GENE-ENVIRONMENT INTERACTION; GENOME; MODELS, GENETIC; MUTATION; SELECTION, GENETIC;

BENEFICIAL MUTATIONS; ERROR THRESHOLD; FISHER'S FUNDAMENTAL THEOREM; MUTAGENESIS; POPULATION GENETICS;

EID: 84891432474     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2013.0329     Document Type: Article

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