-
1
-
-
0030032923
-
Muller's ratchet decreases fitness of a dna-based microbe
-
Andersson, D., and D. Hughes, 1996 Muller's ratchet decreases fitness of a dna-based microbe. Proc. Natl. Acad. Sci. USA 93: 906-907.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 906-907
-
-
Andersson, D.1
Hughes, D.2
-
2
-
-
0006851160
-
Point-mutations, the ratchet, and the initial success of eukaryotic sex: A simulation study
-
Antezana, M., and R. Hudson, 1997 Point-mutations, the ratchet, and the initial success of eukaryotic sex: a simulation study. Evol. Theory Rev. 11: 209-235.
-
(1997)
Evol. Theory Rev.
, vol.11
, pp. 209-235
-
-
Antezana, M.1
Hudson, R.2
-
3
-
-
3543125439
-
Adaptive evolution of asexual populations under Muller's ratchet
-
Bachtrog, D., and I. Gordo, 2004 Adaptive evolution of asexual populations under Muller's ratchet. Evol. Int. J. Org. Evol. 58: 1403-1413.
-
(2004)
Evol. Int. J. Org. Evol.
, vol.58
, pp. 1403-1413
-
-
Bachtrog, D.1
Gordo, I.2
-
4
-
-
77952796777
-
Escherichia coli rpob mutants have increased evolvability in proportion to their fitness defects
-
Barrick, J., M. Kauth, C. Strelioff, and R. Lenski, 2010 Escherichia coli rpob mutants have increased evolvability in proportion to their fitness defects. Mol. Biol. Evol. 27: 1338-1347.
-
(2010)
Mol. Biol. Evol.
, vol.27
, pp. 1338-1347
-
-
Barrick, J.1
Kauth, M.2
Strelioff, C.3
Lenski, R.4
-
5
-
-
0032566768
-
Why sex and recombination?
-
Barton, N., and B. Charlesworth, 1998 Why sex and recombination? Science 281: 1986-1990.
-
(1998)
Science
, vol.281
, pp. 1986-1990
-
-
Barton, N.1
Charlesworth, B.2
-
6
-
-
84993881895
-
Recombination and the immortality of the germ line
-
Bell, G., 1998 Recombination and the immortality of the germ line. J. Evol. Biol. 1: 67-82.
-
(1998)
J. Evol. Biol.
, vol.1
, pp. 67-82
-
-
Bell, G.1
-
7
-
-
0025244957
-
Fitness of RNA virus decreased by Muller's ratchet
-
Chao, L., 1990 Fitness of RNA virus decreased by Muller's ratchet. Nature 348: 454-455.
-
(1990)
Nature
, vol.348
, pp. 454-455
-
-
Chao, L.1
-
8
-
-
84855428748
-
The effects of deleterious mutations on evolution at linked sites
-
Charlesworth, B., 2012 The effects of deleterious mutations on evolution at linked sites. Genetics 190: 5-22.
-
(2012)
Genetics
, vol.190
, pp. 5-22
-
-
Charlesworth, B.1
-
9
-
-
0030668902
-
Rapid fixation of deleterious alleles can be caused by Muller's ratchet
-
Charlesworth, B., and D. Charlesworth, 1997 Rapid fixation of deleterious alleles can be caused by Muller's ratchet. Genet. Res. 70: 63-73.
-
(1997)
Genet. Res.
, vol.70
, pp. 63-73
-
-
Charlesworth, B.1
Charlesworth, D.2
-
10
-
-
33846277942
-
The evolution of sex: Empirical insights into the roles of epistasis and drift
-
De Visser, J., and S. Elena, 2007 The evolution of sex: empirical insights into the roles of epistasis and drift. Nat. Rev. Genet. 8: 139-149.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 139-149
-
-
de Visser, J.1
Elena, S.2
-
11
-
-
33847256353
-
The speed of evolution and maintenance of variation in asexual populations
-
Desai, M. M., D. S. Fisher, and A. W. Murray, 2007 The speed of evolution and maintenance of variation in asexual populations. Curr. Biol. 17: 385-394.
-
(2007)
Curr. Biol.
, vol.17
, pp. 385-394
-
-
Desai, M.M.1
Fisher, D.S.2
Murray, A.W.3
-
12
-
-
0026729636
-
Rapid fitness loss in mammalian RNA virus clones due to Muller's ratchet
-
Duarte, E., D. Clarke, A. Moya, E. Domingo, and J. Holland, 1992 Rapid fitness loss in mammalian RNA virus clones due to Muller's ratchet. Proc. Natl. Acad. Sci. USA 89: 6015-6019.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 6015-6019
-
-
Duarte, E.1
Clarke, D.2
Moya, A.3
Domingo, E.4
Holland, J.5
-
13
-
-
0015133749
-
Self organization of matter and the evolution of biological macromolecules
-
Eigen, M., 1971 Self organization of matter and the evolution of biological macromolecules. Naturwissenschaften 58: 465-523.
-
(1971)
Naturwissenschaften
, vol.58
, pp. 465-523
-
-
Eigen, M.1
-
14
-
-
17144461473
-
Multiple molecular pathways for fitness recovery of an RNA virus debilitated by operation of Muller's ratchet
-
Escarmis, C., M. Davila, and E. Domingo, 1999 Multiple molecular pathways for fitness recovery of an RNA virus debilitated by operation of Muller's ratchet. J. Mol. Biol. 285: 495-505.
-
(1999)
J. Mol. Biol.
, vol.285
, pp. 495-505
-
-
Escarmis, C.1
Davila, M.2
Domingo, E.3
-
15
-
-
0037805770
-
Rapid fitness recovery in mutationally degraded lines of Caenorhabditis elegans
-
Estes, S., and M. Lynch, 2003 Rapid fitness recovery in mutationally degraded lines of Caenorhabditis elegans. Evolution 57: 1022-1030.
-
(2003)
Evolution
, vol.57
, pp. 1022-1030
-
-
Estes, S.1
Lynch, M.2
-
16
-
-
77951561770
-
How often does the ratchet click? Facts, heuristics, asymptotics
-
edited by P. M. Jochen Blath and M. Scheutzow. Cambridge University Press, Cambridge, UK
-
Etheridge, A., P. Pfaffelhuber, and A. Wakolbinger, 2009 How often does the ratchet click? Facts, heuristics, asymptotics, pp. 365-390 in Trends in Stochastic Analysis, edited by P. M. Jochen Blath and M. Scheutzow. Cambridge University Press, Cambridge, UK.
-
(2009)
Trends in Stochastic Analysis
, pp. 365-390
-
-
Etheridge, A.1
Pfaffelhuber, P.2
Wakolbinger, A.3
-
17
-
-
0016110957
-
The evolutionary advantage of recombination
-
Felsenstein, J., 1974 The evolutionary advantage of recombination. Genetics 78: 157-159.
-
(1974)
Genetics
, vol.78
, pp. 157-159
-
-
Felsenstein, J.1
-
18
-
-
0027134973
-
Muller's ratchet and mutational meltdowns
-
Gabriel, W., and R. Burger, 1993 Muller's ratchet and mutational meltdowns. Evolution 47: 1744-1757.
-
(1993)
Evolution
, vol.47
, pp. 1744-1757
-
-
Gabriel, W.1
Burger, R.2
-
19
-
-
84865101054
-
The constraints of finite size in asexual populations and the rate of the ratchet
-
Gessler, D., 1995 The constraints of finite size in asexual populations and the rate of the ratchet. Genet. Res. 49: 135-146.
-
(1995)
Genet. Res.
, vol.49
, pp. 135-146
-
-
Gessler, D.1
-
20
-
-
51849148202
-
Sex and deleterious mutations
-
Gordo, I., and P. Campos, 2008 Sex and deleterious mutations. Genetics 179: 621-626.
-
(2008)
Genetics
, vol.179
, pp. 621-626
-
-
Gordo, I.1
Campos, P.2
-
21
-
-
0034090232
-
The degeneration of asexual haploid populations and the speed of Muller's ratchet
-
Gordo, I., and B. Charlesworth, 2000a The degeneration of asexual haploid populations and the speed of Muller's ratchet. Genetics 154: 1379-1387.
-
(2000)
Genetics
, vol.154
, pp. 1379-1387
-
-
Gordo, I.1
Charlesworth, B.2
-
22
-
-
0034533786
-
On the speed of Muller's ratchet
-
Gordo, I., and B. Charlesworth, 2000b On the speed of Muller's ratchet. Genetics 156: 2137-2140.
-
(2000)
Genetics
, vol.156
, pp. 2137-2140
-
-
Gordo, I.1
Charlesworth, B.2
-
23
-
-
0035989428
-
Muller's ratchet and the pattern of variation at a neutral locus
-
Gordo, I., A. Navarro, and B. Charlesworth, 2002 Muller's ratchet and the pattern of variation at a neutral locus. Genetics 161: 835-848.
-
(2002)
Genetics
, vol.161
, pp. 835-848
-
-
Gordo, I.1
Navarro, A.2
Charlesworth, B.3
-
24
-
-
0018029597
-
The accumulation of deleterious genes in a population
-
Haigh, J., 1978 The accumulation of deleterious genes in a population. Theor. Popul. Biol. 14: 251-267.
-
(1978)
Theor. Popul. Biol.
, vol.14
, pp. 251-267
-
-
Haigh, J.1
-
25
-
-
0030574072
-
Compensatory nearly neutral mutations: Selection without adaptation
-
Hartl, D., and C. Taubes, 1996 Compensatory nearly neutral mutations: selection without adaptation. J. Theor. Biol. 182: 303-309.
-
(1996)
J. Theor. Biol.
, vol.182
, pp. 303-309
-
-
Hartl, D.1
Taubes, C.2
-
26
-
-
41749096136
-
Muller's ratchet and compensatory mutation in Caenorhabditis briggsae mitochondrial genome evolution
-
Howe, D., and D. Denver, 2008 Muller's ratchet and compensatory mutation in Caenorhabditis briggsae mitochondrial genome evolution. BMC Evol. Biol. 8: 62.
-
(2008)
BMC Evol. Biol.
, vol.8
, pp. 62
-
-
Howe, D.1
Denver, D.2
-
27
-
-
84862777341
-
Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes
-
Hughes, J. F., H. Skaletsky, L. G. Brown, T. Pyntikova, T. Graves et al., 2012 Strict evolutionary conservation followed rapid gene loss on human and rhesus Y chromosomes. Nature 483: 82-86.
-
(2012)
Nature
, vol.483
, pp. 82-86
-
-
Hughes, J.F.1
Skaletsky, H.2
Brown, L.G.3
Pyntikova, T.4
Graves, T.5
-
28
-
-
55749093578
-
Loss of least-loaded class in asexual populations due to drift and epistasis
-
Jain, K., 2008 Loss of least-loaded class in asexual populations due to drift and epistasis. Genetics 179(4): 2125-2134.
-
(2008)
Genetics
, vol.179
, Issue.4
, pp. 2125-2134
-
-
Jain, K.1
-
29
-
-
0028294555
-
Muller's ratchet under epistatic selection
-
Kondrashov, A., 1994 Muller's ratchet under epistatic selection. Proc. Natl. Acad. Sci. USA 136: 1469-1473.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.136
, pp. 1469-1473
-
-
Kondrashov, A.1
-
30
-
-
0029130141
-
Contamination of the genome by very slightly deleterious mutations: Why have we not died 100 times over?
-
Kondrashov, A., 1995 Contamination of the genome by very slightly deleterious mutations: Why have we not died 100 times over? J. Theor. Biol. 175: 583-594.
-
(1995)
J Theor. Biol.
, vol.175
, pp. 583-594
-
-
Kondrashov, A.1
-
31
-
-
7344220961
-
Risk of population extinction from fixation of deleterious and reverse mutations
-
Lande, R., 1998 Risk of population extinction from fixation of deleterious and reverse mutations. Genetica 102/103: 21-27.
-
(1998)
Genetica
, vol.102-103
, pp. 21-27
-
-
Lande, R.1
-
32
-
-
79960137718
-
Genetic variation and the fate of beneficial mutations in asexual populations
-
Lang, G. I., D. Botstein, and M. M. Desai, 2011 Genetic variation and the fate of beneficial mutations in asexual populations. Genetics 188: 647-661.
-
(2011)
Genetics
, vol.188
, pp. 647-661
-
-
Lang, G.I.1
Botstein, D.2
Desai, M.M.3
-
33
-
-
33646755364
-
Quantifying the genomic decay paradox due to Muller's ratchet in human mitochondrial DNA
-
Loewe, L., 2006 Quantifying the genomic decay paradox due to Muller's ratchet in human mitochondrial DNA. Genet. Res. Camb. 87: 133-159.
-
(2006)
Genet. Res. Camb.
, vol.87
, pp. 133-159
-
-
Loewe, L.1
-
34
-
-
0030034587
-
Mutation accumulation in transfer RNAs: Molecular evidence for Muller's ratchet in mitochondrial genomes
-
Lynch, M., 1996 Mutation accumulation in transfer RNAs: molecular evidence for Muller's ratchet in mitochondrial genomes. Mol. Biol. Evol. 13: 209-220.
-
(1996)
Mol. Biol. Evol.
, vol.13
, pp. 209-220
-
-
Lynch, M.1
-
35
-
-
0027428093
-
The mutational meltdown in asexual populations
-
Lynch, M., R. Burger, D. Butcher, and W. Gabriel, 1993 The mutational meltdown in asexual populations. J. Hered. 84: 339-344.
-
(1993)
J. Hered.
, vol.84
, pp. 339-344
-
-
Lynch, M.1
Burger, R.2
Butcher, D.3
Gabriel, W.4
-
36
-
-
0028983653
-
Mutation accumulation and the extinction of small populations
-
Lynch, M., J. Conery, and R. Burger, 1995 Mutation accumulation and the extinction of small populations. Am. Nat. 146: 489-518.
-
(1995)
Am. Nat.
, vol.146
, pp. 489-518
-
-
Lynch, M.1
Conery, J.2
Burger, R.3
-
37
-
-
0037590993
-
Fitness distributions in exponentially growing asexual populations
-
Manrubia, S. C., E. Lazaro, and J. Perez-Mercader, 2003 Fitness distributions in exponentially growing asexual populations. Phys. Rev. Lett. 90(18): 188102.
-
(2003)
Phys. Rev. Lett.
, vol.90
, Issue.18
, pp. 188102
-
-
Manrubia, S.C.1
Lazaro, E.2
Perez-Mercader, J.3
-
38
-
-
0034691052
-
The evolution of RNA viruses: A population genetics view
-
Moya, A., S. F. Elena, A. Bracho, R. Miralles, and E. Barrio, 2000 The evolution of RNA viruses: a population genetics view. Proc. Natl. Acad. Sci. USA 97: 6967-6973.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6967-6973
-
-
Moya, A.1
Elena, S.F.2
Bracho, A.3
Miralles, R.4
Barrio, E.5
-
39
-
-
50549201557
-
The relation of recombination to mutational advance
-
Muller, H., 1964 The relation of recombination to mutational advance. Mutat. Res. 1: 2-9.
-
(1964)
Mutat. Res.
, vol.1
, pp. 2-9
-
-
Muller, H.1
-
40
-
-
84865097372
-
Fluctuations of fitness distributions and the rate of Muller's ratchet
-
Neher, R. A., and B. I. Shraiman, 2012 Fluctuations of fitness distributions and the rate of Muller's ratchet. Genetics 191: 1309-1319.
-
(2012)
Genetics
, vol.191
, pp. 1309-1319
-
-
Neher, R.A.1
Shraiman, B.I.2
-
42
-
-
21044438202
-
The rate of compensatory mutation in the DNA bacteriophage fx174
-
Poon, A., and L. Chao, 2005 The rate of compensatory mutation in the DNA bacteriophage fx174. Genetics 170: 989-999.
-
(2005)
Genetics
, vol.170
, pp. 989-999
-
-
Poon, A.1
Chao, L.2
-
43
-
-
0033677913
-
Compensating for our load of mutations: Freezing the meltdown of small populations
-
Poon, A., and S. Otto, 2000 Compensating for our load of mutations: freezing the meltdown of small populations. Evolution 54: 1467-1479.
-
(2000)
Evolution
, vol.54
, pp. 1467-1479
-
-
Poon, A.1
Otto, S.2
-
44
-
-
21044440015
-
The coupon collector and the suppressor mutation: Estimating the number of compensatory mutations by maximum likelihood
-
Poon, A., B. Davis, and L. Chao, 2005 The coupon collector and the suppressor mutation: estimating the number of compensatory mutations by maximum likelihood. Genetics 170: 1323-1332.
-
(2005)
Genetics
, vol.170
, pp. 1323-1332
-
-
Poon, A.1
Davis, B.2
Chao, L.3
-
45
-
-
0028158739
-
Degeneration of a nonrecombining chromosome
-
Rice, W., 1994 Degeneration of a nonrecombining chromosome. Science 263: 230-232.
-
(1994)
Science
, vol.263
, pp. 230-232
-
-
Rice, W.1
-
47
-
-
37848998555
-
The traveling-wave approach to asexual evolution: Muller's ratchet and speed of adaptation
-
Rouzine, I., E. Brunet, and C. Wilke, 2008 The traveling-wave approach to asexual evolution: Muller's ratchet and speed of adaptation. Theor. Popul. Biol. 73: 24-46.
-
(2008)
Theor. Popul. Biol.
, vol.73
, pp. 24-46
-
-
Rouzine, I.1
Brunet, E.2
Wilke, C.3
-
48
-
-
72949085559
-
The properties of adaptive walks in evolving populations of fungus
-
Schoustra, S., T. Bataillon, D. Gifford, and R. Kassen, 2009 The properties of adaptive walks in evolving populations of fungus. PLoS Biol. 7: e1000250.
-
(2009)
PLoS Biol.
, vol.7
-
-
Schoustra, S.1
Bataillon, T.2
Gifford, D.3
Kassen, R.4
-
49
-
-
0030830534
-
Deleterious mutation and extinction: The role of variable mutational effects, synergistic epistasis, beneficial mutations, and degree of outcrossing
-
Schultz, S., and M. Lynch, 1997 Deleterious mutation and extinction: the role of variable mutational effects, synergistic epistasis, beneficial mutations, and degree of outcrossing. Evolution 51: 1363-1371.
-
(1997)
Evolution
, vol.51
, pp. 1363-1371
-
-
Schultz, S.1
Lynch, M.2
-
50
-
-
77749292827
-
Gene genealogies strongly distorted by weakly interfering mutations in constant environments
-
Seger, J., W. A. Smith, J. J. Perry, J. Hunn, Z. A. Kaliszewska et al., 2010 Gene genealogies strongly distorted by weakly interfering mutations in constant environments. Genetics 184: 529-545.
-
(2010)
Genetics
, vol.184
, pp. 529-545
-
-
Seger, J.1
Smith, W.A.2
Perry, J.J.3
Hunn, J.4
Kaliszewska, Z.A.5
-
51
-
-
34247349509
-
Understanding the evolutionary fate of finite populations: The dynamics of mutational effects
-
Silander, O., O. Tenaillon, and L. Chao, 2007 Understanding the evolutionary fate of finite populations: the dynamics of mutational effects. PLoS Biol. 5: e94.
-
(2007)
PLoS Biol.
, vol.5
-
-
Silander, O.1
Tenaillon, O.2
Chao, L.3
-
52
-
-
35549001303
-
Mutational interference and the progression of Muller's ratchet when mutations have a broad range of deleterious effects
-
Soderberg, R., and O. Berg, 2007 Mutational interference and the progression of Muller's ratchet when mutations have a broad range of deleterious effects. Genetics 177: 971-986.
-
(2007)
Genetics
, vol.177
, pp. 971-986
-
-
Soderberg, R.1
Berg, O.2
-
53
-
-
3042684874
-
-
Oxford University Press, Oxford
-
Stephan, W., and Y. Kim, 2002, Recent Applications of Diffusion Theory to Population Genetics. Oxford University Press, Oxford, pp. 72-93.
-
(2002)
Recent Applications of Diffusion Theory to Population Genetics
, pp. 72-93
-
-
Stephan, W.1
Kim, Y.2
-
54
-
-
77951595254
-
Rate and effects of spontaneous mutations that affect fitness in mutator Escherichia coli
-
Trindade, S., L. Perfeito, and I. Gordo, 2010 Rate and effects of spontaneous mutations that affect fitness in mutator Escherichia coli. Philos. Trans. R. Soc. B Biol. Sci. 365: 1177-1186.
-
(2010)
Philos. Trans. R. Soc. B Biol. Sci.
, vol.365
, pp. 1177-1186
-
-
Trindade, S.1
Perfeito, L.2
Gordo, I.3
-
55
-
-
0025588451
-
Quantitative variation in finite parthenogenetic populations: What stops Muller's ratchet in the absence of recombination?
-
Wagner, G., and W. Gabriel, 1990 Quantitative variation in finite parthenogenetic populations: What stops Muller's ratchet in the absence of recombination? Evolution 44: 715-731.
-
(1990)
Evolution
, vol.44
, pp. 715-731
-
-
Wagner, G.1
Gabriel, W.2
-
56
-
-
0034972360
-
Mutational meltdown in laboratory yeast populations
-
Zeyl, C., M. Mizesko, and J. de Visser, 2001 Mutational meltdown in laboratory yeast populations. Evolution 55: 909-917.
-
(2001)
Evolution
, vol.55
, pp. 909-917
-
-
Zeyl, C.1
Mizesko, M.2
de Visser, J.3
|