-
1
-
-
0033840455
-
Human immunodeficiency virus type 1 mutations selected in patients falling efavirenz combination therapy
-
Bacheler, L. T., E. D. Anton, P. Kudish, D. Baker, J. Bunville, K. Krakowski, L. Bolling, M. Aujay, X. V. Wang, D. Ellis, M. F. Becker, A. L. Lasut, H. J. George, D. R. Spalding, G. Hollis, and K. Abremske. 2000. Human immunodeficiency virus type 1 mutations selected in patients falling efavirenz combination therapy. Antimicrob. Agents Chemother. 44:2475-2484.
-
(2000)
Antimicrob. Agents Chemother.
, vol.44
, pp. 2475-2484
-
-
Bacheler, L.T.1
Anton, E.D.2
Kudish, P.3
Baker, D.4
Bunville, J.5
Krakowski, K.6
Bolling, L.7
Aujay, M.8
Wang, X.V.9
Ellis, D.10
Becker, M.F.11
Lasut, A.L.12
George, H.J.13
Spalding, D.R.14
Hollis, G.15
Abremske, K.16
-
2
-
-
1342325435
-
Defining a molecular mechanism of synergy between nucleoside and nonnucleoside AIDS drugs
-
Basarapathruni, A., C. M. Bailey, and K. S. Anderson. 2004. Defining a molecular mechanism of synergy between nucleoside and nonnucleoside AIDS drugs. J. Biol. Chem. 279:6221-6224.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 6221-6224
-
-
Basarapathruni, A.1
Bailey, C.M.2
Anderson, K.S.3
-
3
-
-
0024438889
-
Specificity and mechanism of error-prone replication by human immunodeficiency virus-1 reverse transcriptase
-
Bebenek, K., J. Abbotts, J. D. Roberts, S. H. Wilson, and T. A. Kunkel. 1989. Specificity and mechanism of error-prone replication by human immunodeficiency virus-1 reverse transcriptase. J. Biol. Chem. 264:16948-16956.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 16948-16956
-
-
Bebenek, K.1
Abbotts, J.2
Roberts, J.D.3
Wilson, S.H.4
Kunkel, T.A.5
-
4
-
-
0027215750
-
Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots
-
Bebenek, K., J. Abbotts, S. H. Wilson, and T. A. Kunkel. 1993. Error-prone polymerization by HIV-1 reverse transcriptase. Contribution of template-primer misalignment, miscoding, and termination probability to mutational hot spots. J. Biol. Chem. 268:10324-10334.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 10324-10334
-
-
Bebenek, K.1
Abbotts, J.2
Wilson, S.H.3
Kunkel, T.A.4
-
5
-
-
0026714957
-
The effects of dNTP pool imbalances on frameshift fidelity during DNA replication
-
Bebenek, K., J. D. Roberts, and T. A. Kunkel. 1992. The effects of dNTP pool imbalances on frameshift fidelity during DNA replication. J. Biol. Chem. 267:3589-3596.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 3589-3596
-
-
Bebenek, K.1
Roberts, J.D.2
Kunkel, T.A.3
-
6
-
-
0033934724
-
Effects of amino acid substitutions at position 115 on the fidelity of human immunodeficiency virus type 1 reverse transcriptase
-
Boyer, P. L., and S. H. Hughes. 2000. Effects of amino acid substitutions at position 115 on the fidelity of human immunodeficiency virus type 1 reverse transcriptase. J. Virol. 74:6494-6500.
-
(2000)
J. Virol.
, vol.74
, pp. 6494-6500
-
-
Boyer, P.L.1
Hughes, S.H.2
-
7
-
-
0028228748
-
High rates of frameshift mutations within homo-oligomeric runs during a single cycle of retroviral replication
-
Burns, D. P., and H. M. Temin. 1994. High rates of frameshift mutations within homo-oligomeric runs during a single cycle of retroviral replication. J. Virol. 68:4196-4203.
-
(1994)
J. Virol.
, vol.68
, pp. 4196-4203
-
-
Burns, D.P.1
Temin, H.M.2
-
8
-
-
0028924567
-
Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors
-
Esnouf, R., J. Ren, C. Ross, Y. Jones, D. Stammers, and D. Stuart. 1995. Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors. Struct. Biol. 2:303-308.
-
(1995)
Struct. Biol.
, vol.2
, pp. 303-308
-
-
Esnouf, R.1
Ren, J.2
Ross, C.3
Jones, Y.4
Stammers, D.5
Stuart, D.6
-
9
-
-
0033257958
-
Human immunodeficiency viruses in the developing world
-
Essex, M. 1999. Human immunodeficiency viruses in the developing world. Adv. Virus Res. 53:71-88.
-
(1999)
Adv. Virus Res.
, vol.53
, pp. 71-88
-
-
Essex, M.1
-
10
-
-
0035984019
-
A mutation in the 3′ region of the human immunodeficiency virus type 1 reverse transcriptase (Y318F) associated with nonnucleoside reverase transcriptase inhibitor resistance
-
Harrigan, P. R., M. Salim, D. K. Stammers, B. Wynhoven, Z. L. Brumme, P. McKenna, B. Larder, and S. D. Kemp. 2002. A mutation in the 3′ region of the human immunodeficiency virus type 1 reverse transcriptase (Y318F) associated with nonnucleoside reverase transcriptase inhibitor resistance. J. Virol. 76:6836-6840.
-
(2002)
J. Virol.
, vol.76
, pp. 6836-6840
-
-
Harrigan, P.R.1
Salim, M.2
Stammers, D.K.3
Wynhoven, B.4
Brumme, Z.L.5
McKenna, P.6
Larder, B.7
Kemp, S.D.8
-
11
-
-
0032573488
-
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance
-
Huang, H., R. Chopra, G. L. Verdine, and S. C. Harrison. 1998. Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Science 282:1669-1675.
-
(1998)
Science
, vol.282
, pp. 1669-1675
-
-
Huang, H.1
Chopra, R.2
Verdine, G.L.3
Harrison, S.C.4
-
12
-
-
0037223722
-
Amino acid substitutions at position 190 of human immunodeficiency virus type 1 reverse transcriptase increase susceptibility to delavirdine and impair virus replication
-
Huang, W., A. Gamarnik, K. Limoli, C. J. Petropoulos, and J. M. Whitcomb. 2003. Amino acid substitutions at position 190 of human immunodeficiency virus type 1 reverse transcriptase increase susceptibility to delavirdine and impair virus replication. J. Virol. 77:1512-1523.
-
(2003)
J. Virol.
, vol.77
, pp. 1512-1523
-
-
Huang, W.1
Gamarnik, A.2
Limoli, K.3
Petropoulos, C.J.4
Whitcomb, J.M.5
-
13
-
-
0037388383
-
Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
-
Johnson, S. J., J. S. Taylor, and L. S. Beese. 2003. Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations. Proc. Natl. Acad. Sci. USA 100:3895-3900.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3895-3900
-
-
Johnson, S.J.1
Taylor, J.S.2
Beese, L.S.3
-
14
-
-
0000937442
-
Fidelity analysis of HIV-1 reverse transcriptase mutants with an altered amino-acid sequence at residues Leu74, Olu89, Tyr115, Tyr183 and Met184
-
Jonckheere, H., E. De Clercq, and J. Anne. 2000. Fidelity analysis of HIV-1 reverse transcriptase mutants with an altered amino-acid sequence at residues Leu74, Olu89, Tyr115, Tyr183 and Met184. Eur. J. Biochem. 267:2658-2665.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 2658-2665
-
-
Jonckheere, H.1
De Clercq, E.2
Anne, J.3
-
15
-
-
0032906836
-
Human immunodeficiency virus type 1 subtypes differ in disease progression
-
Kanki, P. J., D. J. Hamel, J. L. Sankale, C. Hsieh, I. Thior, F. Barin, S. A. Woodcock, A. Gueye-Ndiaye, E. Zhang, M. Montano, T. Siby, R. Marlink, I. NDoye, M. E. Essex, and, S. MBoup. 1999. Human immunodeficiency virus type 1 subtypes differ in disease progression. J. Infect. Dis. 179:68-73.
-
(1999)
J. Infect. Dis.
, vol.179
, pp. 68-73
-
-
Kanki, P.J.1
Hamel, D.J.2
Sankale, J.L.3
Hsieh, C.4
Thior, I.5
Barin, F.6
Woodcock, S.A.7
Gueye-Ndiaye, A.8
Zhang, E.9
Montano, M.10
Siby, T.11
Marlink, R.12
Ndoye, I.13
Essex, M.E.14
Mboup, S.15
-
16
-
-
0027092323
-
Mechanism and fidelity of HIV reverse transcriptase
-
Kati, W. M., K. A. Johnson, L. F. Jerva, and K. S. Anderson. 1992. Mechanism and fidelity of HIV reverse transcriptase. J. Biol. Chem. 267:25988-25997.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 25988-25997
-
-
Kati, W.M.1
Johnson, K.A.2
Jerva, L.F.3
Anderson, K.S.4
-
17
-
-
0026562720
-
Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene
-
Kimpton, J., and M. Emerman. 1992. Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene. J. Virol. 66:2232-2239.
-
(1992)
J. Virol.
, vol.66
, pp. 2232-2239
-
-
Kimpton, J.1
Emerman, M.2
-
18
-
-
0026693137
-
Crystal structure at 3.5 a resolution of HIV-1 reverse transcriptase complexed with an inhibitor
-
Kohlstaedt, L. A., J. Wang, J. M. Friedman, P. A. Rice, and T. A. Steitz. 1992. Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science 256:1783-1790.
-
(1992)
Science
, vol.256
, pp. 1783-1790
-
-
Kohlstaedt, L.A.1
Wang, J.2
Friedman, J.M.3
Rice, P.A.4
Steitz, T.A.5
-
20
-
-
0028332029
-
Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2′,3′-didehydro-2′, 3′-dideoxythymidine in cell culture
-
Lacey, S. F., and B. A. Larder. 1994. Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2′,3′-didehydro-2′,3′-dideoxythymidine in cell culture. Antimicrob. Agents Chemother. 38:1428-1432.
-
(1994)
Antimicrob. Agents Chemother.
, vol.38
, pp. 1428-1432
-
-
Lacey, S.F.1
Larder, B.A.2
-
21
-
-
0031861823
-
Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates
-
Li, Y., Y. Kong, S. Korolev, and G. Waksman. 1998. Crystal structures of the Klenow fragment of Thermus aquaticus DNA polymerase I complexed with deoxyribonucleoside triphosphates. Protein Sci. 7:1116-1123.
-
(1998)
Protein Sci.
, vol.7
, pp. 1116-1123
-
-
Li, Y.1
Kong, Y.2
Korolev, S.3
Waksman, G.4
-
22
-
-
0028917760
-
Genetic diversity of the envelope glycoprotein from human immunodeficiency virus type 1 isolates of African origin
-
Louwagie, J., W. Janssens, J. Mascola, L. Heyndrickx, P. Hegerich, G. van der Groen, F. E. McCutchan, and D. S. Burke. 1995. Genetic diversity of the envelope glycoprotein from human immunodeficiency virus type 1 isolates of African origin. J. Virol. 69:263-271.
-
(1995)
J. Virol.
, vol.69
, pp. 263-271
-
-
Louwagie, J.1
Janssens, W.2
Mascola, J.3
Heyndrickx, L.4
Hegerich, P.5
Van Der Groen, G.6
McCutchan, F.E.7
Burke, D.S.8
-
23
-
-
0037343865
-
Mutagenic outcome of combined antiviral drug treatment during human immunodeficiency virus type 1 replication
-
Mansky, L. M. 2003. Mutagenic outcome of combined antiviral drug treatment during human immunodeficiency virus type 1 replication. Virology 307:116-121.
-
(2003)
Virology
, vol.307
, pp. 116-121
-
-
Mansky, L.M.1
-
24
-
-
0033819409
-
3′-azido-3′-deoxythymidine (zidovudine) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency type 1
-
Mansky, L. M., and L. C. Bernard. 2000. 3′-Azido-3′- deoxythymidine (zidovudine) and AZT-resistant reverse transcriptase can increase the in vivo mutation rate of human immunodeficiency type 1. J. Virol. 74:9532-9539.
-
(2000)
J. Virol.
, vol.74
, pp. 9532-9539
-
-
Mansky, L.M.1
Bernard, L.C.2
-
25
-
-
0037302270
-
Influence of reverse transcriptase variants, drugs, and Vpr on human immunodeficiency virus type 1 mutation frequencies
-
Mansky, L. M., E. Le Rouzic, S. Benichou, and L. C. Gajary. 2003. Influence of reverse transcriptase variants, drugs, and Vpr on human immunodeficiency virus type 1 mutation frequencies. J. Virol. 77:2071-2080.
-
(2003)
J. Virol.
, vol.77
, pp. 2071-2080
-
-
Mansky, L.M.1
Le Rouzic, E.2
Benichou, S.3
Gajary, L.C.4
-
26
-
-
0036721138
-
Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutation frequencies
-
Mansky, L. M., D. K. Pearl, and L. C. Gajary. 2002. Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutation frequencies. J. Virol. 76:9253-9259.
-
(2002)
J. Virol.
, vol.76
, pp. 9253-9259
-
-
Mansky, L.M.1
Pearl, D.K.2
Gajary, L.C.3
-
27
-
-
0033925801
-
The interaction of Vpr with uracil DNA glycosylase modulates the human immunodeficiency virus type 1 in vivo mutation rate
-
Mansky, L. M., S. Preveral, L. Selig, R. Benarous, and S. Benichou. 2000. The interaction of Vpr with uracil DNA glycosylase modulates the human immunodeficiency virus type 1 in vivo mutation rate. J. Virol. 74:7039-7047.
-
(2000)
J. Virol.
, vol.74
, pp. 7039-7047
-
-
Mansky, L.M.1
Preveral, S.2
Selig, L.3
Benarous, R.4
Benichou, S.5
-
28
-
-
0029075130
-
Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase
-
Mansky, L. M., and H. M. Temin. 1995. Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. J. Virol. 69:5087-5094.
-
(1995)
J. Virol.
, vol.69
, pp. 5087-5094
-
-
Mansky, L.M.1
Temin, H.M.2
-
29
-
-
0032506228
-
Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism
-
Meyer, P. R., S. E. Matsuura, A. G. So, and W. A. Scott. 1998. Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism. Proc. Natl. Acad. Sci. USA 95:13471-13476.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13471-13476
-
-
Meyer, P.R.1
Matsuura, S.E.2
So, A.G.3
Scott, W.A.4
-
30
-
-
0036233261
-
Effects of specific zidovudine resistance mutations and substrate structure on nucleotide-dependent primer unblocking by human immunodeficiency virus type 1 reverse transcriptase
-
Meyer, P. R., S. E. Matsuura, A. A. Tolun, I. Pfeifer, A. G. So, J. W. Mellors, and W. A. Scott. 2002. Effects of specific zidovudine resistance mutations and substrate structure on nucleotide-dependent primer unblocking by human immunodeficiency virus type 1 reverse transcriptase. Antimicrob. Agents Chemother. 46:1540-1545.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 1540-1545
-
-
Meyer, P.R.1
Matsuura, S.E.2
Tolun, A.A.3
Pfeifer, I.4
So, A.G.5
Mellors, J.W.6
Scott, W.A.7
-
31
-
-
0032545420
-
Mutational analysis of Tyr-318 within the non-nucleoside reverse transcriptase inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase
-
Pelemans, H., R. M. Esnonf, H. Jonckheere, E. De Clercq, and J. Balzarini. 1998. Mutational analysis of Tyr-318 within the non-nucleoside reverse transcriptase inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase. J. Biol. Chem. 273:34234-34239.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34234-34239
-
-
Pelemans, H.1
Esnonf, R.M.2
Jonckheere, H.3
De Clercq, E.4
Balzarini, J.5
-
32
-
-
0141705300
-
Drug resistance profiles of recombinant reverse transcriptases from human immunodeficiency virus type 1 subtypes A/E, B, and C
-
Quan, Y., B. G. Brenner, R. G. Marlink, M. Essex, T. Kurimura, and M. A. Wainberg. 2003. Drug resistance profiles of recombinant reverse transcriptases from human immunodeficiency virus type 1 subtypes A/E, B, and C. AIDS Res. Hum. Retroviruses 19:743-753.
-
(2003)
AIDS Res. Hum. Retroviruses
, vol.19
, pp. 743-753
-
-
Quan, Y.1
Brenner, B.G.2
Marlink, R.G.3
Essex, M.4
Kurimura, T.5
Wainberg, M.A.6
-
33
-
-
0037175023
-
Mechanistic studies to understand the progressive development of resistance in human immunodeficiency virus type 1 reverse transcriptase to abacavir
-
Ray, A. S., A. Basavapathruni, and K. S. Anderson. 2002. Mechanistic studies to understand the progressive development of resistance in human immunodeficiency virus type 1 reverse transcriptase to abacavir. J. Biol. Chem. 277:40479-40490.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40479-40490
-
-
Ray, A.S.1
Basavapathruni, A.2
Anderson, K.S.3
-
34
-
-
0028947588
-
High resolution structures of HIV-1 RT from four RT-inhibitor complexes
-
Ren, J., R. Esnouf, E. Garman, D. Somers, C. Ross, I. Kirby, J. Keeling, G. Darby, Y. Jones, D. Stuart, and D. Stammers. 1995. High resolution structures of HIV-1 RT from four RT-inhibitor complexes. Struct. Biol. 2:293-302.
-
(1995)
Struct. Biol.
, vol.2
, pp. 293-302
-
-
Ren, J.1
Esnouf, R.2
Garman, E.3
Somers, D.4
Ross, C.5
Kirby, I.6
Keeling, J.7
Darby, G.8
Jones, Y.9
Stuart, D.10
Stammers, D.11
-
35
-
-
0029150042
-
Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the mechanism of inhibition by nonnucleoside inhibitors
-
Rittinger, K., G. Divita, and R. S. Goody. 1995. Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the mechanism of inhibition by nonnucleoside inhibitors. Proc. Natl. Acad. Sci. USA 92:8046-8049.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8046-8049
-
-
Rittinger, K.1
Divita, G.2
Goody, R.S.3
-
36
-
-
0034615972
-
HIV-1 nomenclature proposal
-
Robertson, D. L., J. P. Anderson, J. A. Bradac, J. K. Carr, B. Foley, R. K. Funkbouser, F. Gao, B. H. Hahn, M. L. Kalish, C. Kuiken, G. H. Learn, T. Leitner, F. McCutchan, S. Osmanov, M. Peeters, D. Pieniazek, M. Salminen, P. M. Sharp, S. Wolinsky, and B. Korber. 2000. HIV-1 nomenclature proposal. Science 288:55-56.
-
(2000)
Science
, vol.288
, pp. 55-56
-
-
Robertson, D.L.1
Anderson, J.P.2
Bradac, J.A.3
Carr, J.K.4
Foley, B.5
Funkbouser, R.K.6
Gao, F.7
Hahn, B.H.8
Kalish, M.L.9
Kuiken, C.10
Learn, G.H.11
Leitner, T.12
McCutchan, F.13
Osmanov, S.14
Peeters, M.15
Pieniazek, D.16
Salminen, M.17
Sharp, P.M.18
Wolinsky, S.19
Korber, B.20
more..
-
37
-
-
18744365757
-
Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA
-
Sarafianos, S. G., A. D. Clark, Jr., K. Das, S. Tuske, J. J. Birktoft, P. Ilankumaran, A. R. Ramesha, J. M. Sayer, D. M. Jerina, P. L. Boyer, S. H. Hughes, and E. Arnold. 2002. Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA. EMBO J. 21:6614-6624.
-
(2002)
EMBO J.
, vol.21
, pp. 6614-6624
-
-
Sarafianos, S.G.1
Clark Jr., A.D.2
Das, K.3
Tuske, S.4
Birktoft, J.J.5
Ilankumaran, P.6
Ramesha, A.R.7
Sayer, J.M.8
Jerina, D.M.9
Boyer, P.L.10
Hughes, S.H.11
Arnold, E.12
-
38
-
-
0035000024
-
Augmentation of human immunodeficiency virus type 1 subtype E (CRF01_AE) multiple-drug resistance by insertion of a foreign 11-amino-acid fragment into the reverse transcriptase
-
Sato, H., Y. Tomita, K. Ebisawa, A. Hachiya, K. Shibamura, T. Shiino, R. Yang, M. Tatsumi, K. Gushi, H. Umeyama, S. Oka, Y. Takebe, and Y. Nagai. 2001. Augmentation of human immunodeficiency virus type 1 subtype E (CRF01_AE) multiple-drug resistance by insertion of a foreign 11-amino-acid fragment into the reverse transcriptase. J. Virol. 75:5604-5613.
-
(2001)
J. Virol.
, vol.75
, pp. 5604-5613
-
-
Sato, H.1
Tomita, Y.2
Ebisawa, K.3
Hachiya, A.4
Shibamura, K.5
Shiino, T.6
Yang, R.7
Tatsumi, M.8
Gushi, K.9
Umeyama, H.10
Oka, S.11
Takebe, Y.12
Nagai, Y.13
-
39
-
-
0033102304
-
Highly active antiretroviral therapy (HAART) for the treatment of infection with human immunodeficiency virus type 1
-
Shafer, R. W., and D. A. Vuitton. 1999. Highly active antiretroviral therapy (HAART) for the treatment of infection with human immunodeficiency virus type 1. Biomed. Pharmacother. 53:73-86.
-
(1999)
Biomed. Pharmacother.
, vol.53
, pp. 73-86
-
-
Shafer, R.W.1
Vuitton, D.A.2
-
40
-
-
0028271687
-
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1
-
Smerdon, S. J., J. Jager, J. Wang, L. A. Kohlstaedt, A. J. Chirino, J. M. Friedman, P. A. Rice, and T. A. Steitz. 1994. Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA 91:3911-3915.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3911-3915
-
-
Smerdon, S.J.1
Jager, J.2
Wang, J.3
Kohlstaedt, L.A.4
Chirino, A.J.5
Friedman, J.M.6
Rice, P.A.7
Steitz, T.A.8
-
41
-
-
0028925773
-
Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors
-
Spence, R. A., W. M. Kati, K. S. Anderson, and K. A. Johnson. 1995. Mechanism of inhibition of HIV-1 reverse transcriptase by nonnucleoside inhibitors. Science 267:988-993.
-
(1995)
Science
, vol.267
, pp. 988-993
-
-
Spence, R.A.1
Kati, W.M.2
Anderson, K.S.3
Johnson, K.A.4
-
42
-
-
0025950055
-
Resistance to ddl and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase
-
St Clair, M. H., J. L. Martin, G. Tudor-Williams, M. C. Bach, C. L. Vavro, D. M. King, P. Kellam, S. D. Kemp, and B. A. Larder. 1991. Resistance to ddl and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase. Science 253:1557-1559.
-
(1991)
Science
, vol.253
, pp. 1557-1559
-
-
St. Clair, M.H.1
Martin, J.L.2
Tudor-Williams, G.3
Bach, M.C.4
Vavro, C.L.5
King, D.M.6
Kellam, P.7
Kemp, S.D.8
Larder, B.A.9
-
43
-
-
0028172345
-
Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance
-
Tantillo, C., J. Ding, A. Jacobo-Molina, R. G. Nanni, P. L. Boyer, S. H. Hughes, R. Pauwels, K. Andries, P. A. Janssen, and E. Arnold. 1994. Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance. J. Mol. Biol. 243:369-387.
-
(1994)
J. Mol. Biol.
, vol.243
, pp. 369-387
-
-
Tantillo, C.1
Ding, J.2
Jacobo-Molina, A.3
Nanni, R.G.4
Boyer, P.L.5
Hughes, S.H.6
Pauwels, R.7
Andries, K.8
Janssen, P.A.9
Arnold, E.10
-
44
-
-
1642276330
-
Structural basis for substrate selection by 17 RNA polymerase
-
Temiakov, D., V. Patlan, M. Anikin, W. T. McAllister, S. Yokoyama, and D. G. Vassylyev. 2004. Structural basis for substrate selection by 17 RNA polymerase. Cell 116:381-391.
-
(2004)
Cell
, vol.116
, pp. 381-391
-
-
Temiakov, D.1
Patlan, V.2
Anikin, M.3
McAllister, W.T.4
Yokoyama, S.5
Vassylyev, D.G.6
-
45
-
-
0030945276
-
Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89
-
Tisdale, M., T. Alnadaf, and D. Consens. 1997. Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89. Antimicrob. Agents Chemother. 41:1094-1098.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1094-1098
-
-
Tisdale, M.1
Alnadaf, T.2
Consens, D.3
-
46
-
-
1342313235
-
The structural mechanism of translocation and helicase activity in T7 RNA polymerase
-
Yin, Y. W., and T. A. Steitz. 2004. The structural mechanism of translocation and helicase activity in T7 RNA polymerase. Cell 116:393-404.
-
(2004)
Cell
, vol.116
, pp. 393-404
-
-
Yin, Y.W.1
Steitz, T.A.2
|