Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator

Molecular and Cellular Biology

Volumn 20, Issue 16, 2000, Pages 6138-6146

  Bloch, D B ^a   Nakajima, A ^a   Gulick, T ^a   Chiche, J D ^a   Orth, D ^a   De la Monte, S M ^a   Bloch, K D ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; HORMONE RECEPTOR; RETINOIC ACID; TRANSCRIPTION FACTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS INCLUSION BODY; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; EMBRYO; GENE ACTIVATION; GENE CONTROL; GENE DISRUPTION; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENE STRUCTURE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REPORTER GENE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANTIGENS, NUCLEAR; AUTOANTIGENS; CELL NUCLEUS; DNA, COMPLEMENTARY; HL-60 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; NUCLEAR PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

ATRA; MAMMALIA;

EID: 0033860185     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.16.6138-6146.2000     Document Type: Article

References (46)

1. The PHD finger: Implications for chromatin-mediated transcriptional regulation
2. Reporter genes: Application to the study of mammalian gene transcription
3. Identification of a novel nuclear domain
4. Structural and functional hetereogeneity of nuclear bodies
5. Identification and characterization of a leukocyte-specific component of the nuclear body
6. Molecular analysis of acute promyelocytic leukemia breakpoint cluster region on chromosome 17
7. Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds
8. LySp100-associated nuclear domains (LANDS): Description of a new class of subnuclear structures and their relationship to PML nuclear bodies
9. The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor a gene to a novel transcribed locus
10. Structure and ligand of a histone acetyltransferase bromodomain
11. Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling
12. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
13. The APECED polyglandular autoimmune syndrome protein, AIRE-1, contains the SAND domain and is probably a transcription factor
14. Manipulation of adenovirus vectors
15. DEAF-1, a novel protein that binds an essential region in a Deformed response element
16. The bromodomain: A conserved sequence found in human, Drosophila and yeast proteins
17. Structure, organization, and dynamics of promyelocytic leukemia protein nuclear bodies
18. Human cytomegalovirus immediate early interaction with host nuclear structures: Definition of an immediate transcription environment
19. The bromodomain revisited
20. Molecular cloning of two new interferon-induced, highly-related nuclear phosphoproteins
21. Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML
22. Primary biliary cirrhosis
23. Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body
24. NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)
25. A possible involvement of TIF1α and TIF1β in the epigenetic control of transcription by nuclear receptors
26. The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18
27. Chromatin components as part of a putative transcriptional repressing complex
28. Rearrangements and aberrant expression of the retinoic acid receptor α gene in acute promyelocytic leukemias
29. A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2
30. A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex
31. Deconstructing a disease: RARα, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
32. Positional cloning of the APECED gene
33. A novel rapid assay for chloramphenicol acetyltransferase gene expression
34. PML induces a novel caspase-independent death process
35. Determination of nucleotide sequence in DNA
36. Interaction of Sp100 and HP1 proteins: A link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment
37. How proteins enter the nucleus
38. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione-S-transferase
39. Nuclear dots: Actors on many stages
40. Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1
41. Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis
42. TIF1γ, a novel member of the transcriptional intermediary factor 1 family
43. Pml is essential for multiple apoptotic pathways
44. Role of PML in cell growth and the retinoic acid pathway
45. Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1