-
1
-
-
73149115486
-
Aire's partners in the molecular control of immunological tolerance
-
Abramson J, Giraud M, Benoist C, Mathis D (2010) Aire's partners in the molecular control of immunological tolerance. Cell 140:123-135.
-
(2010)
Cell
, vol.140
, pp. 123-135
-
-
Abramson, J.1
Giraud, M.2
Benoist, C.3
Mathis, D.4
-
2
-
-
22344449972
-
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
-
Derbinski J, et al. (2005) Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J Exp Med 202:33-45.
-
(2005)
J Exp Med
, vol.202
, pp. 33-45
-
-
Derbinski, J.1
-
3
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson MS, et al. (2002) Projection of an immunological self shadow within the thymus by the aire protein. Science 298:1395-1401.
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
-
4
-
-
18844362882
-
Chromosomal clustering of genes controlled by the aire transcription factor
-
Johnnidis JB, et al. (2005) Chromosomal clustering of genes controlled by the aire transcription factor. Proc Natl Acad Sci USA 102:7233-7238.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 7233-7238
-
-
Johnnidis, J.B.1
-
5
-
-
38649131259
-
Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism
-
Derbinski J, Pinto S, Rösch S, Hexel K, Kyewski B (2008) Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism. Proc Natl Acad Sci USA 105:657-662.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 657-662
-
-
Derbinski, J.1
Pinto, S.2
Rösch, S.3
Hexel, K.4
Kyewski, B.5
-
6
-
-
33646165128
-
A central role for central tolerance
-
Kyewski B, Klein L (2006) A central role for central tolerance. Annu Rev Immunol 24: 571-606.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 571-606
-
-
Kyewski, B.1
Klein, L.2
-
7
-
-
0003328368
-
Evidence for large domains of similarly expressed genes in the Drosophila genome
-
Spellman PT, Rubin GM (2002) Evidence for large domains of similarly expressed genes in the Drosophila genome. J Biol 1:5.
-
(2002)
J Biol
, vol.1
, pp. 5
-
-
Spellman, P.T.1
Rubin, G.M.2
-
9
-
-
25844496592
-
The role of chromatin structure in regulating the expression of clustered genes
-
Sproul D, Gilbert N, Bickmore WA (2005) The role of chromatin structure in regulating the expression of clustered genes. Nat Rev Genet 6:775-781.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 775-781
-
-
Sproul, D.1
Gilbert, N.2
Bickmore, W.A.3
-
10
-
-
33644618035
-
Gene regulation and large-scale chromatin organization in the nucleus
-
Dillon N (2006) Gene regulation and large-scale chromatin organization in the nucleus. Chromosome Res 14:117-126.
-
(2006)
Chromosome Res
, vol.14
, pp. 117-126
-
-
Dillon, N.1
-
11
-
-
33646872978
-
Chromatin signatures of pluripotent cell lines
-
Azuara V, et al. (2006) Chromatin signatures of pluripotent cell lines. Nat Cell Biol 8: 532-538.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 532-538
-
-
Azuara, V.1
-
12
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein BE, et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125:315-326.
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
-
13
-
-
33646882068
-
Polycomb complexes repress developmental regulators in murine embryonic stem cells
-
Boyer LA, et al. (2006) Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature 441:349-353.
-
(2006)
Nature
, vol.441
, pp. 349-353
-
-
Boyer, L.A.1
-
14
-
-
67349190247
-
Linking DNA methylation and histone modification: Patterns and paradigms
-
Cedar H, Bergman Y (2009) Linking DNA methylation and histone modification: Patterns and paradigms. Nat Rev Genet 10:295-304.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 295-304
-
-
Cedar, H.1
Bergman, Y.2
-
15
-
-
0242300262
-
Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse
-
Tamamaki N, et al. (2003) Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse. J Comp Neurol 467:60-79.
-
(2003)
J Comp Neurol
, vol.467
, pp. 60-79
-
-
Tamamaki, N.1
-
16
-
-
37549071821
-
Promiscuous gene expression and the developmental dynamics of medullary thymic epithelial cells
-
Gäbler J, Arnold J, Kyewski B (2007) Promiscuous gene expression and the developmental dynamics of medullary thymic epithelial cells. Eur J Immunol 37:3363-3372.
-
(2007)
Eur J Immunol
, vol.37
, pp. 3363-3372
-
-
Gäbler, J.1
Arnold, J.2
Kyewski, B.3
-
17
-
-
56749184864
-
Ectopic expression of peripheraltissue antigens in the thymic epithelium: Probabilistic, monoallelic, misinitiated
-
Villaseñor J, Besse W, Benoist C, Mathis D (2008) Ectopic expression of peripheraltissue antigens in the thymic epithelium: Probabilistic, monoallelic, misinitiated. Proc Natl Acad Sci USA 105:15854-15859.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15854-15859
-
-
Villaseñor, J.1
Besse, W.2
Benoist, C.3
Mathis, D.4
-
18
-
-
35748941369
-
Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire
-
Gray D, Abramson J, Benoist C, Mathis D (2007) Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire. J Exp Med 204:2521-2528.
-
(2007)
J Exp Med
, vol.204
, pp. 2521-2528
-
-
Gray, D.1
Abramson, J.2
Benoist, C.3
Mathis, D.4
-
19
-
-
0036384806
-
The human cytomegalovirus immediate-early promoter is transcriptionally active in undifferentiated mouse embryonic stem cells
-
Ward CM, Stern PL (2002) The human cytomegalovirus immediate-early promoter is transcriptionally active in undifferentiated mouse embryonic stem cells. Stem Cells 20: 472-475.
-
(2002)
Stem Cells
, vol.20
, pp. 472-475
-
-
Ward, C.M.1
Stern, P.L.2
-
20
-
-
0033222349
-
Killing of brain tumor cells by hypoxia-responsive element mediated expression of BAX
-
Ruan H, et al. (1999) Killing of brain tumor cells by hypoxia-responsive element mediated expression of BAX. Neoplasia 1:431-437.
-
(1999)
Neoplasia
, vol.1
, pp. 431-437
-
-
Ruan, H.1
-
21
-
-
33845497677
-
Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells
-
Holtkamp S, et al. (2006) Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells. Blood 108:4009-4017.
-
(2006)
Blood
, vol.108
, pp. 4009-4017
-
-
Holtkamp, S.1
-
22
-
-
2942628047
-
Functional expression of connexin57 in horizontal cells of the mouse retina
-
Hombach S, et al. (2004) Functional expression of connexin57 in horizontal cells of the mouse retina. Eur J Neurosci 19:2633-2640.
-
(2004)
Eur J Neurosci
, vol.19
, pp. 2633-2640
-
-
Hombach, S.1
-
23
-
-
0942288397
-
Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters
-
Gotter J, Brors B, Hergenhahn M, Kyewski B (2004) Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters. J Exp Med 199:155-166.
-
(2004)
J Exp Med
, vol.199
, pp. 155-166
-
-
Gotter, J.1
Brors, B.2
Hergenhahn, M.3
Kyewski, B.4
-
24
-
-
1842427830
-
The evolutionary dynamics of eukaryotic gene order
-
Hurst LD, Pál C, Lercher MJ (2004) The evolutionary dynamics of eukaryotic gene order. Nat Rev Genet 5:299-310.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 299-310
-
-
Hurst, L.D.1
Pál, C.2
Lercher, M.J.3
-
25
-
-
45849137524
-
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression
-
Org T, et al. (2008) The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression. EMBO Rep 9:370-376.
-
(2008)
EMBO Rep
, vol.9
, pp. 370-376
-
-
Org, T.1
-
26
-
-
56749174388
-
Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity
-
Koh AS, et al. (2008) Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity. Proc Natl Acad Sci USA 105:15878-15883.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15878-15883
-
-
Koh, A.S.1
-
27
-
-
56749161528
-
Transcriptional regulation by AIRE: Molecular mechanisms of central tolerance
-
Peterson P, Org T, Rebane A (2008) Transcriptional regulation by AIRE: Molecular mechanisms of central tolerance. Nat Rev Immunol 8:948-957.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 948-957
-
-
Peterson, P.1
Org, T.2
Rebane, A.3
-
28
-
-
70450192681
-
AIRE activated tissue specific genes have histone modifications associated with inactive chromatin
-
Org T, et al. (2009) AIRE activated tissue specific genes have histone modifications associated with inactive chromatin. Hum Mol Genet 18:4699-4710.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4699-4710
-
-
Org, T.1
-
29
-
-
77955602966
-
Global relevance of Aire binding to hypomethylated lysine-4 of histone-3
-
Koh AS, Kingston RE, Benoist C, Mathis D (2010) Global relevance of Aire binding to hypomethylated lysine-4 of histone-3. Proc Natl Acad Sci USA 107:13016-13021.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13016-13021
-
-
Koh, A.S.1
Kingston, R.E.2
Benoist, C.3
Mathis, D.4
-
30
-
-
7044220808
-
Regulating self-tolerance by deregulating gene expression
-
Gotter J, Kyewski B (2004) Regulating self-tolerance by deregulating gene expression. Curr Opin Immunol 16:741-745.
-
(2004)
Curr Opin Immunol
, vol.16
, pp. 741-745
-
-
Gotter, J.1
Kyewski, B.2
-
31
-
-
7244227645
-
Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation
-
Gallegos AM, Bevan MJ (2004) Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation. J Exp Med 200:1039-1049.
-
(2004)
J Exp Med
, vol.200
, pp. 1039-1049
-
-
Gallegos, A.M.1
Bevan, M.J.2
-
32
-
-
67650507153
-
The thymic medulla: A unique microenvironment for intercellular self-antigen transfer
-
Koble C, Kyewski B (2009) The thymic medulla: A unique microenvironment for intercellular self-antigen transfer. J Exp Med 206:1505-1513.
-
(2009)
J Exp Med
, vol.206
, pp. 1505-1513
-
-
Koble, C.1
Kyewski, B.2
-
33
-
-
67651158788
-
The impact of negative selection on thymocyte migration in the medulla
-
Le Borgne M, et al. (2009) The impact of negative selection on thymocyte migration in the medulla. Nat Immunol 10:823-830.
-
(2009)
Nat Immunol
, vol.10
, pp. 823-830
-
-
Le Borgne, M.1
-
34
-
-
0033984067
-
Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells
-
Klein L, Klugmann M, Nave KA, Tuohy VK, Kyewski B (2000) Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells. Nat Med 6:56-61.
-
(2000)
Nat Med
, vol.6
, pp. 56-61
-
-
Klein, L.1
Klugmann, M.2
Nave, K.A.3
Tuohy, V.K.4
Kyewski, B.5
|