Mouse thymic epithelial cell lines expressing "Aire" and peripheral tissue-specific antigens reproduce in vitro negative selection of T cells

Experimental Cell Research

Volumn 317, Issue 14, 2011, Pages 2019-2030

  Yamaguchi, Yoshitaka ^a   Takayanagi, Atsushi ^a,b   Chen, Jiabing ^b   Sakai, Kosuke ^b   Kudoh, Jun ^a,b   Shimizu, Nobuyoshi ^a  

^a KEIO UNIVERSITY   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

AIRE; Negative selection; Thymocytes and apoptosis; Tolerance

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; PROTEASOME; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; CELL LINE; CELL SELECTION; COCULTURE; DNA FLANKING REGION; EPITHELIUM CELL; IMMUNOLOGICAL SYNAPSE; IN VITRO STUDY; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; T LYMPHOCYTE; THYMOCYTE; THYMUS DISEASE; TISSUE SPECIFICITY; TRANSGENIC MOUSE;

MUS MUSCULUS;

EID: 79960085650     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2011.05.002     Document Type: Article

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