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Volumn 115, Issue 11, 2005, Pages 3239-3249

Human skin cells support thymus-independent T cell development

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; AUTOIMMUNE REGULATOR PROTEIN; CD14 ANTIGEN; CD3 ANTIGEN; CD34 ANTIGEN; GAMMA INTERFERON; LYMPHOTOXIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXN1; TRANSCRIPTION FACTOR HOXA3; TRANSCRIPTION FACTOR PAX1; UNCLASSIFIED DRUG;

EID: 27644465295     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI24731     Document Type: Article
Times cited : (85)

References (54)
  • 1
    • 0030754129 scopus 로고    scopus 로고
    • Essential role of the thymus to reconstitute naive (CD45RA+) T-helper cells after human allogeneic bone marrow transplantation
    • Heitger, A., et al. 1997. Essential role of the thymus to reconstitute naive (CD45RA+) T-helper cells after human allogeneic bone marrow transplantation. Blood. 90:850-857.
    • (1997) Blood , vol.90 , pp. 850-857
    • Heitger, A.1
  • 2
    • 0016439669 scopus 로고
    • Age involution in the normal human adult thymus
    • Simpson, J.G., Gray, E.S., and Beck, J.S. 1975. Age involution in the normal human adult thymus. Clin. Exp. Immunol. 19:261-265.
    • (1975) Clin. Exp. Immunol. , vol.19 , pp. 261-265
    • Simpson, J.G.1    Gray, E.S.2    Beck, J.S.3
  • 3
    • 0018280378 scopus 로고
    • Ultrastructure of the age-involuted adult human thymus
    • von Gaudecker, B. 1978. Ultrastructure of the age-involuted adult human thymus. Cell Tissue Res. 186:507-525.
    • (1978) Cell Tissue Res. , vol.186 , pp. 507-525
    • Von Gaudecker, B.1
  • 4
    • 0028784287 scopus 로고
    • Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset
    • Galy, A., Travis, M., Cen, D., and Chen, B. 1995. Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset. Immunity. 3:459-473.
    • (1995) Immunity , vol.3 , pp. 459-473
    • Galy, A.1    Travis, M.2    Cen, D.3    Chen, B.4
  • 5
    • 0022401934 scopus 로고
    • A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations
    • Kingston, R., Jenkinson, E.J., and Owen, J.J. 1985. A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations. Nature. 317:811-813.
    • (1985) Nature , vol.317 , pp. 811-813
    • Kingston, R.1    Jenkinson, E.J.2    Owen, J.J.3
  • 6
    • 0037089413 scopus 로고    scopus 로고
    • Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo
    • Weijer, K., et al. 2002. Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo. Blood. 99:2752-2759.
    • (2002) Blood , vol.99 , pp. 2752-2759
    • Weijer, K.1
  • 7
    • 0023753744 scopus 로고
    • The SCID-hu mouse: Murine model for the analysis of human hematolymphoid differentiation and function
    • McCune, J.M., et al. 1988. The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function. Science. 241:1632-1639.
    • (1988) Science , vol.241 , pp. 1632-1639
    • McCune, J.M.1
  • 8
    • 18144448857 scopus 로고    scopus 로고
    • Efficient generation of human T cells from a tissue-engineered thymic organoid
    • Poznansky, M.C., et al. 2000. Efficient generation of human T cells from a tissue-engineered thymic organoid. Nat. Biotechnol. 18:729-734.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 729-734
    • Poznansky, M.C.1
  • 9
    • 0031751321 scopus 로고    scopus 로고
    • T-lymphopoietic capacity of cord blood-derived CD34+ progenitor cells
    • Gardner, J.P., et al. 1998. T-lymphopoietic capacity of cord blood-derived CD34+ progenitor cells. Exp. Hematol. 26:991-999.
    • (1998) Exp. Hematol. , vol.26 , pp. 991-999
    • Gardner, J.P.1
  • 10
    • 0030007288 scopus 로고    scopus 로고
    • In vitro T lymphopoiesis of human and rhesus CD34+ progenitor cells
    • Rosenzweig, M., et al. 1996. In vitro T lymphopoiesis of human and rhesus CD34+ progenitor cells. Blood. 87:4040-4048.
    • (1996) Blood , vol.87 , pp. 4040-4048
    • Rosenzweig, M.1
  • 11
    • 0029958003 scopus 로고    scopus 로고
    • Induction of recombination activating gene expression in a human lymphoid progenitor cell line: Requirement of two separate signals from stromal cells and cytokines
    • Tagoh, H., et al. 1996. Induction of recombination activating gene expression in a human lymphoid progenitor cell line: requirement of two separate signals from stromal cells and cytokines. Blood. 88:4463-4473.
    • (1996) Blood , vol.88 , pp. 4463-4473
    • Tagoh, H.1
  • 12
    • 0030199773 scopus 로고    scopus 로고
    • Development of CD4 and CD8 single positive T cells in human thymus organ culture: IL-7 promotes human T cell production by supporting immature T cells
    • Yeoman, H., Clark, D.R., and DeLuca, D. 1996. Development of CD4 and CD8 single positive T cells in human thymus organ culture: IL-7 promotes human T cell production by supporting immature T cells. Dev. Comp. Immunol. 20:241-263.
    • (1996) Dev. Comp. Immunol. , vol.20 , pp. 241-263
    • Yeoman, H.1    Clark, D.R.2    DeLuca, D.3
  • 13
    • 0027992021 scopus 로고
    • Human CD34+ fetal liver stem cells differentiate to T cells in a mouse thymic microenvironment
    • Plum, J., DeSmedt, M., Defresne, M.P., Leclercq, G., and Vandekerckhove, B. 1994. Human CD34+ fetal liver stem cells differentiate to T cells in a mouse thymic microenvironment. Blood. 84:1587-1593.
    • (1994) Blood , vol.84 , pp. 1587-1593
    • Plum, J.1    DeSmedt, M.2    Defresne, M.P.3    Leclercq, G.4    Vandekerckhove, B.5
  • 14
    • 0025782755 scopus 로고
    • Human T cells in the SCID-hu mouse are phenotypically normal and functionally competent
    • Krowka, J.F., Sarin, S., Namikawa, R., McCune, J.M., and Kaneshima, H. 1991. Human T cells in the SCID-hu mouse are phenotypically normal and functionally competent. J. Immunol. 146:3751-3756.
    • (1991) J. Immunol. , vol.146 , pp. 3751-3756
    • Krowka, J.F.1    Sarin, S.2    Namikawa, R.3    McCune, J.M.4    Kaneshima, H.5
  • 15
    • 0030070265 scopus 로고    scopus 로고
    • Generation of human T lymphocytes from bone marrow CD34+ cells in vitro
    • Freedman, A.R., Zhu, H., Levine, J.D., Kalams, S., and Scadden, D.T. 1996. Generation of human T lymphocytes from bone marrow CD34+ cells in vitro. Nat. Med. 2:46-51.
    • (1996) Nat. Med. , vol.2 , pp. 46-51
    • Freedman, A.R.1    Zhu, H.2    Levine, J.D.3    Kalams, S.4    Scadden, D.T.5
  • 16
    • 0030155109 scopus 로고    scopus 로고
    • In vitro T lymphopoiesis: A model system for stem cell gene therapy for AIDS
    • Rosenzweig, M., Marks, D.F., Hempel, D., and Johnson, R.P. 1996. In vitro T lymphopoiesis: a model system for stem cell gene therapy for AIDS. J. Med. Primatol. 25:192-200.
    • (1996) J. Med. Primatol. , vol.25 , pp. 192-200
    • Rosenzweig, M.1    Marks, D.F.2    Hempel, D.3    Johnson, R.P.4
  • 17
    • 0035496231 scopus 로고    scopus 로고
    • Lymphostromal interactions in thymic development and function
    • Anderson, G., and Jenkinson, E.J. 2001. Lymphostromal interactions in thymic development and function. Nat. Rev. Immunol. 1:31-40.
    • (2001) Nat. Rev. Immunol. , vol.1 , pp. 31-40
    • Anderson, G.1    Jenkinson, E.J.2
  • 18
    • 8544265317 scopus 로고    scopus 로고
    • Forkhead-box transcription factors and their role in the immune system
    • Coffer, P.J., and Burgering, B.M. 2004. Forkhead-box transcription factors and their role in the immune system. Nat. Rev. Immunol. 4:889-899.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 889-899
    • Coffer, P.J.1    Burgering, B.M.2
  • 19
    • 0022595487 scopus 로고
    • The human thymic microenvironment: Thymic epithelium contains specific keratins associated with early and late stages of epidermal keratinocyte maturation
    • Laster, A.J., Itoh, T., Palker, T.J., and Haynes, B.F. 1986. The human thymic microenvironment: thymic epithelium contains specific keratins associated with early and late stages of epidermal keratinocyte maturation. Differentiation. 31:67-77.
    • (1986) Differentiation , vol.31 , pp. 67-77
    • Laster, A.J.1    Itoh, T.2    Palker, T.J.3    Haynes, B.F.4
  • 20
    • 17844384528 scopus 로고    scopus 로고
    • Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
    • Rangarajan, A., et al. 2001. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J. 20:3427-3436.
    • (2001) EMBO J. , vol.20 , pp. 3427-3436
    • Rangarajan, A.1
  • 21
    • 0033735838 scopus 로고    scopus 로고
    • Microenvironmental regulation of T cell development in the thymus
    • Anderson, G., Harman, B.C., Hare, K.J., and Jenkinson, E.J. 2000. Microenvironmental regulation of T cell development in the thymus. Semin. Immunol. 12:457-464.
    • (2000) Semin. Immunol. , vol.12 , pp. 457-464
    • Anderson, G.1    Harman, B.C.2    Hare, K.J.3    Jenkinson, E.J.4
  • 22
    • 0036779662 scopus 로고    scopus 로고
    • Development of alphabeta T cells in the human thymus
    • Spits, H. 2002. Development of alphabeta T cells in the human thymus. Nat. Rev. Immunol. 2:760-772.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 760-772
    • Spits, H.1
  • 23
    • 17444372347 scopus 로고    scopus 로고
    • Changes in thymic function with age and during the treatment of HIV infection
    • Douek, D.C., et al. 1998. Changes in thymic function with age and during the treatment of HIV infection. Nature. 396:690-695.
    • (1998) Nature , vol.396 , pp. 690-695
    • Douek, D.C.1
  • 24
    • 0035476891 scopus 로고    scopus 로고
    • Differential effects of notch Iigands delta-1 and jagged-1 in human lymphoid differentiation
    • Jaleco, A.C., et al. 2001. Differential effects of notch Iigands delta-1 and jagged-1 in human lymphoid differentiation. J. Exp. Med. 194:991-1002.
    • (2001) J. Exp. Med. , vol.194 , pp. 991-1002
    • Jaleco, A.C.1
  • 26
    • 0035313174 scopus 로고    scopus 로고
    • Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells
    • Karanu, F.N., et al. 2001. Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells. Blood. 97:1960-1967.
    • (2001) Blood , vol.97 , pp. 1960-1967
    • Karanu, F.N.1
  • 27
    • 0036916440 scopus 로고    scopus 로고
    • Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
    • Schmitt, T.M., and Zuniga-Pflucker, J.C. 2002. Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. Immunity. 17:749-756.
    • (2002) Immunity , vol.17 , pp. 749-756
    • Schmitt, T.M.1    Zuniga-Pflucker, J.C.2
  • 28
    • 13544262340 scopus 로고    scopus 로고
    • Induction of T cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro
    • LaMotte-Mohs, R.N., Herer, E., and Zuniga-Pflucker, J.C. 2004. Induction of T cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro. Blood. 105:1431-1439.
    • (2004) Blood , vol.105 , pp. 1431-1439
    • LaMotte-Mohs, R.N.1    Herer, E.2    Zuniga-Pflucker, J.C.3
  • 29
    • 0036125096 scopus 로고    scopus 로고
    • Cord blood CD34+ cells differentiate into dermal dendritic cells in co-culture with cutaneous fibroblasts or stromal cells
    • Mollah, Z.U.A., Aiba, S., Manome, H., Yoshino, Y., and Tagami, H. 2002. Cord blood CD34+ cells differentiate into dermal dendritic cells in co-culture with cutaneous fibroblasts or stromal cells. J. Invest. Dermatol. 118:450-460.
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 450-460
    • Mollah, Z.U.A.1    Aiba, S.2    Manome, H.3    Yoshino, Y.4    Tagami, H.5
  • 30
    • 0037112047 scopus 로고    scopus 로고
    • Projection of an immunological self shadow within the thymus by the Aire protein
    • Anderson, M.S., et al. 2002. Projection of an immunological self shadow within the thymus by the Aire protein. Science. 298:1395-1401.
    • (2002) Science , vol.298 , pp. 1395-1401
    • Anderson, M.S.1
  • 31
    • 0037790522 scopus 로고    scopus 로고
    • Autoimmune regulator: From loss of function to autoimmunity
    • Pitkanen, J., and Peterson, P. 2003. Autoimmune regulator: from loss of function to autoimmunity. Genes Immun. 4:12-21.
    • (2003) Genes Immun. , vol.4 , pp. 12-21
    • Pitkanen, J.1    Peterson, P.2
  • 32
    • 0036228844 scopus 로고    scopus 로고
    • Lymphoid organs contain diverse cells expressing self-molecules
    • author reply 336
    • Pugliese, A., and Diez, J. 2002. Lymphoid organs contain diverse cells expressing self-molecules [letter]. Nat. Immunol. 3:335-336; author reply 336.
    • (2002) Nat. Immunol. , vol.3 , pp. 335-336
    • Pugliese, A.1    Diez, J.2
  • 33
    • 0036222578 scopus 로고    scopus 로고
    • Cellular environment and freedom of gene expression
    • author reply 336
    • Pietropaolo, M., Giannoukakis, N., and Trucco, M. 2002. Cellular environment and freedom of gene expression [letter]. Nat. Immunol. 3:335; author reply 336.
    • (2002) Nat. Immunol. , vol.3 , pp. 335
    • Pietropaolo, M.1    Giannoukakis, N.2    Trucco, M.3
  • 34
    • 0242624626 scopus 로고    scopus 로고
    • Lymphotoxin pathway directs thymic Aire expression
    • Chin, R.K., et al. 2003. Lymphotoxin pathway directs thymic Aire expression. Nat. Immunol. 4:1121-1127.
    • (2003) Nat. Immunol. , vol.4 , pp. 1121-1127
    • Chin, R.K.1
  • 35
    • 0022377333 scopus 로고
    • Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon
    • Aggarwal, B.B., Eessalu, T.E., and Hass, P.E. 1985. Characterization of receptors for human tumour necrosis factor and their regulation by gamma-interferon. Nature. 318:665-667.
    • (1985) Nature , vol.318 , pp. 665-667
    • Aggarwal, B.B.1    Eessalu, T.E.2    Hass, P.E.3
  • 36
    • 0034434467 scopus 로고    scopus 로고
    • Expression of lymphotoxin-alpha by keratinocytes: A further mediator for the lichenoid reaction
    • Middel, P., et al. 2000. Expression of lymphotoxin-alpha by keratinocytes: a further mediator for the lichenoid reaction. Pathobiology. 68:291-300.
    • (2000) Pathobiology , vol.68 , pp. 291-300
    • Middel, P.1
  • 37
    • 1142311548 scopus 로고    scopus 로고
    • A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues
    • Adamson, K.A., Pearce, S.H., Lamb, J.R., Seckl, J.R., and Howie, S.E. 2004. A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues. J. Pathol. 202:180-187.
    • (2004) J. Pathol. , vol.202 , pp. 180-187
    • Adamson, K.A.1    Pearce, S.H.2    Lamb, J.R.3    Seckl, J.R.4    Howie, S.E.5
  • 38
    • 0942288397 scopus 로고    scopus 로고
    • Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters
    • Gotter, J., Brors, B., Hergenhahn, M., and Kyewski, B. 2004. Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters. J. Exp. Med. 199:155-166.
    • (2004) J. Exp. Med. , vol.199 , pp. 155-166
    • Gotter, J.1    Brors, B.2    Hergenhahn, M.3    Kyewski, B.4
  • 39
    • 0028000121 scopus 로고
    • New member of the winged-helix protein family disrupted in mouse and rat nude mutations
    • Nehls, M., Pfeifer, D., Schorpp, M., Hedrich, H., and Boehm, T. 1994. New member of the winged-helix protein family disrupted in mouse and rat nude mutations. Nature. 372:103-107.
    • (1994) Nature , vol.372 , pp. 103-107
    • Nehls, M.1    Pfeifer, D.2    Schorpp, M.3    Hedrich, H.4    Boehm, T.5
  • 40
    • 0036174684 scopus 로고    scopus 로고
    • Role of the nude gene in epithelial terminal differentiation
    • Baxter, R.M., and Brissette, J.L. 2002. Role of the nude gene in epithelial terminal differentiation. J. Invest. Dermatol. 118:303-309.
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 303-309
    • Baxter, R.M.1    Brissette, J.L.2
  • 41
    • 3543071500 scopus 로고    scopus 로고
    • Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: Contrasting roles of FOXN1 and Akt
    • Janes, S.M., Ofstad, T.A., Campbell, D.H., Watt, F.M., and Prowse, D.M. 2004. Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt. J. Cell Sci. 117:4157-4168.
    • (2004) J. Cell Sci. , vol.117 , pp. 4157-4168
    • Janes, S.M.1    Ofstad, T.A.2    Campbell, D.H.3    Watt, F.M.4    Prowse, D.M.5
  • 42
    • 0029030722 scopus 로고
    • The role of Hoxa-3 in mouse thymus and thyroid development
    • Manley, N.R., and Capecchi, M.R. 1995. The role of Hoxa-3 in mouse thymus and thyroid development. Development. 121:1989-2003.
    • (1995) Development , vol.121 , pp. 1989-2003
    • Manley, N.R.1    Capecchi, M.R.2
  • 43
    • 21644472188 scopus 로고    scopus 로고
    • HOXA3 induces cell migration in endothelial and epithelial cells promoting angiogenesis and wound repair
    • Mace, K.A., Hansen, S.L., Myers, C., Young, D.M., and Boudreau, N. 2005. HOXA3 induces cell migration in endothelial and epithelial cells promoting angiogenesis and wound repair. J. Cell Sci. 118:2567-2577.
    • (2005) J. Cell Sci. , vol.118 , pp. 2567-2577
    • Mace, K.A.1    Hansen, S.L.2    Myers, C.3    Young, D.M.4    Boudreau, N.5
  • 44
    • 0030069119 scopus 로고    scopus 로고
    • Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation
    • Wallin, J., et al. 1996. Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation. Development. 122:23-30.
    • (1996) Development , vol.122 , pp. 23-30
    • Wallin, J.1
  • 46
    • 0031023770 scopus 로고    scopus 로고
    • Downregulation of CD1 marks acquisition of functional maturation of human thymocytes and defines a control point in late stages of human T cell development
    • Res, P., Blom, B., Hori, T., Weijer, K., and Spits, H. 1997. Downregulation of CD1 marks acquisition of functional maturation of human thymocytes and defines a control point in late stages of human T cell development. J. Exp. Med. 185:141-152.
    • (1997) J. Exp. Med. , vol.185 , pp. 141-152
    • Res, P.1    Blom, B.2    Hori, T.3    Weijer, K.4    Spits, H.5
  • 48
    • 0033042560 scopus 로고    scopus 로고
    • Thymic microenvironments, 3-D versus 2-D?
    • van Ewijk, W., et al. 1999. Thymic microenvironments, 3-D versus 2-D? Semin. Immunol. 11:57-64.
    • (1999) Semin. Immunol. , vol.11 , pp. 57-64
    • Van Ewijk, W.1
  • 49
    • 0032030895 scopus 로고    scopus 로고
    • Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands
    • Manley, N.R., and Capecchi, M.R. 1998. Hox group 3 paralogs regulate the development and migration of the thymus, thyroid, and parathyroid glands. Dev. Biol. 195:1-15.
    • (1998) Dev. Biol. , vol.195 , pp. 1-15
    • Manley, N.R.1    Capecchi, M.R.2
  • 50
    • 2942659675 scopus 로고    scopus 로고
    • Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo
    • Hozumi, K., et al. 2004. Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nat. Immunol. 5:638-644.
    • (2004) Nat. Immunol. , vol.5 , pp. 638-644
    • Hozumi, K.1
  • 51
    • 0034192461 scopus 로고    scopus 로고
    • Stimulation of human epidermal differentiation by Delta-Notch signalling at the boundaries of stem-cell clusters
    • Lowell, S., Jones, P., Le Roux, I., Dunne, J., and Watt, F.M. 2000. Stimulation of human epidermal differentiation by Delta-Notch signalling at the boundaries of stem-cell clusters. Curr. Biol. 10:491-500.
    • (2000) Curr. Biol. , vol.10 , pp. 491-500
    • Lowell, S.1    Jones, P.2    Le Roux, I.3    Dunne, J.4    Watt, F.M.5
  • 52
    • 0030962571 scopus 로고    scopus 로고
    • Malignancy after renal transplantation: Analysis of incidence and risk factors in 1700 patients followed during a 25-year period
    • Hiesse, C., et al. 1997. Malignancy after renal transplantation: analysis of incidence and risk factors in 1700 patients followed during a 25-year period. Transplant. Proc. 29:831-833.
    • (1997) Transplant. Proc. , vol.29 , pp. 831-833
    • Hiesse, C.1
  • 53
    • 0035960576 scopus 로고    scopus 로고
    • Highly disparate xenogeneic skin graft tolerance induction by fetal pig thymus in thymectomized mice: Conditioning requirements and the role of coimplantation of fetal pig liver
    • Zhao, Y., et al. 2001. Highly disparate xenogeneic skin graft tolerance induction by fetal pig thymus in thymectomized mice: conditioning requirements and the role of coimplantation of fetal pig liver. Transplantation. 72:1608-1615.
    • (2001) Transplantation , vol.72 , pp. 1608-1615
    • Zhao, Y.1
  • 54
    • 0036127889 scopus 로고    scopus 로고
    • Improved assessment of T-cell receptor (TCR) VB repertoire in clinical specimens: Combination of TCR-CDR3 spectratyping with flow cytometry-based TCR VB frequency analysis
    • Pilch, H., et al. 2002. Improved assessment of T-cell receptor (TCR) VB repertoire in clinical specimens: combination of TCR-CDR3 spectratyping with flow cytometry-based TCR VB frequency analysis. Clin. Diagn. Lab. Immunol. 9:257-266.
    • (2002) Clin. Diagn. Lab. Immunol. , vol.9 , pp. 257-266
    • Pilch, H.1


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