The tumor microenvironment and strategies to improve drug distribution

Frontiers in Oncology

Volumn 3 JUN, Issue , 2013, Pages

  Saggar, Jasdeep K ^a   Yu, Man ^a   Tan, Qian ^a   Tannock, Ian F ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Drug distribution; Drug penetration; Hypoxia activated pro drugs; Pharmacodynamic markers; Solid tumor; Tumor microenvironment

Indexed keywords

BANOXANTRONE; BECLIN 1; CETUXIMAB; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; ETOPOSIDE; HYPOXIA INDUCIBLE FACTOR 1; MELPHALAN; MITOXANTRONE; OXYGEN; PROTEIN P53; TIRAPAZAMINE; TOPOTECAN; TRASTUZUMAB; VINBLASTINE; VINCRISTINE;

AUTOPHAGY; AUTORADIOGRAPHY; CANCER CHEMOTHERAPY; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; DRUG DISTRIBUTION; HUMAN; HYPOXIA; MICROCIRCULATION; OXYGEN CONSUMPTION; PHASE 3 CLINICAL TRIAL (TOPIC); PROGRESSION FREE SURVIVAL; PROSTATE CANCER; REOXYGENATION; SHORT SURVEY; TISSUE PRESSURE; TUMOR HYPOXIA; TUMOR MICROENVIRONMENT; TUMOR VASCULARIZATION;

EID: 84891053440     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2013.00154     Document Type: Short Survey

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