-
1
-
-
14444280360
-
Pharmacodynamics of immediate and delayed effects of paclitaxel: Role of slow apoptosis and intracellular drug retention
-
Au JLS, Li D, Gan Y, Gao X, Johnson AL, Johnston J, Millenbaugh NJ, Jang SH, Kuh, HJ, Chen, CT and Wientjes MG (1998) Pharmacodynamics of immediate and delayed effects of paclitaxel: Role of slow apoptosis and intracellular drug retention. Cancer Res 58:2141-2148.
-
(1998)
Cancer Res
, vol.58
, pp. 2141-2148
-
-
Au, J.L.S.1
Li, D.2
Gan, Y.3
Gao, X.4
Johnson, A.L.5
Johnston, J.6
Millenbaugh, N.J.7
Jang, S.H.8
Kuh, H.J.9
Chen, C.T.10
Wientjes, M.G.11
-
2
-
-
0028354777
-
Characterization of a human myeloid leukemia cell line highly resistant to taxol
-
Bhalla K, Huang Y, Tang C, Self S, Ray S, Mahoney ME, Ponnathpur V, Tourkina E, Ibrado AM, Bullock G and Willingham MC (1994) Characterization of a human myeloid leukemia cell line highly resistant to taxol. Leukemia 8:465-475.
-
(1994)
Leukemia
, vol.8
, pp. 465-475
-
-
Bhalla, K.1
Huang, Y.2
Tang, C.3
Self, S.4
Ray, S.5
Mahoney, M.E.6
Ponnathpur, V.7
Tourkina, E.8
Ibrado, A.M.9
Bullock, G.10
Willingham, M.C.11
-
3
-
-
0028908695
-
Substoichiometric binding of taxol suppresses microtubule dynamics
-
Derry WB, Wilson L and Jordan MA (1995) Substoichiometric binding of taxol suppresses microtubule dynamics. Biochemistry 34:2203-2211.
-
(1995)
Biochemistry
, vol.34
, pp. 2203-2211
-
-
Derry, W.B.1
Wilson, L.2
Jordan, M.A.3
-
4
-
-
0024537994
-
Distribution and activity of antineoplastic drugs in a tumor model
-
Durand RE (1989) Distribution and activity of antineoplastic drugs in a tumor model. J Natl Cancer Inst 81:146-152.
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 146-152
-
-
Durand, R.E.1
-
5
-
-
0025296555
-
Slow penetration of anthracyclines into spheroids and tumors: A therapeutical advantage?
-
Durand RE (1990) Slow penetration of anthracyclines into spheroids and tumors: A therapeutical advantage? Cancer Chemother Pharmacol 26:198-204.
-
(1990)
Cancer Chemother Pharmacol
, vol.26
, pp. 198-204
-
-
Durand, R.E.1
-
6
-
-
0026582526
-
Relationship between the penetration, binding and average concentration of cytostatic drug in human tumor spheroids
-
Erlanson M, Daniel-Szolgay E and Carlsson J (1992) Relationship between the penetration, binding and average concentration of cytostatic drug in human tumor spheroids. Cancer Chemother Pharmacol 29:343-353.
-
(1992)
Cancer Chemother Pharmacol
, vol.29
, pp. 343-353
-
-
Erlanson, M.1
Daniel-Szolgay, E.2
Carlsson, J.3
-
7
-
-
0018713387
-
Interstitial diffusion of macromolecules in the rat mesentery
-
Fox JR and Wayland H (1979) Interstitial diffusion of macromolecules in the rat mesentery. Microvasc Res 18:255-276.
-
(1979)
Microvasc Res
, vol.18
, pp. 255-276
-
-
Fox, J.R.1
Wayland, H.2
-
8
-
-
0028914290
-
The clinical applications of the histoculture drug response assay
-
Furukawa T, Kubota T and Hoffman RM (1995) The clinical applications of the histoculture drug response assay. Clin Cancer Res 1:305-311.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 305-311
-
-
Furukawa, T.1
Kubota, T.2
Hoffman, R.M.3
-
9
-
-
0032425823
-
Relationship between paclitaxel activity and pathobiology of human solid tumors
-
Gan Y, Wientjes MG and Au JLS (1998) Relationship between paclitaxel activity and pathobiology of human solid tumors. Clin Cancer Res 4:2949-2955.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2949-2955
-
-
Gan, Y.1
Wientjes, M.G.2
Au, J.L.S.3
-
11
-
-
0000991611
-
Kinetics and mathematical modeling of paclitaxel efflux by P-glycoprotein in BC19 cells
-
Jang SH, Kuh HJ, Wientjes MG and Au JLS (1998) Kinetics and mathematical modeling of paclitaxel efflux by P-glycoprotein in BC19 cells. Proc Am Assoc Cancer Res 39:218.
-
(1998)
Proc Am Assoc Cancer Res
, vol.39
, pp. 218
-
-
Jang, S.H.1
Kuh, H.J.2
Wientjes, M.G.3
Au, J.L.S.4
-
12
-
-
0028158664
-
Synergistic interaction between cisplatin and taxol in human ovarian carcinoma cells in vitro
-
Jekunen AP, Christen RD, Shalinsky DR and Howell SB (1994) Synergistic interaction between cisplatin and taxol in human ovarian carcinoma cells in vitro. Br J Cancer 69:299-306.
-
(1994)
Br J Cancer
, vol.69
, pp. 299-306
-
-
Jekunen, A.P.1
Christen, R.D.2
Shalinsky, D.R.3
Howell, S.B.4
-
13
-
-
0027360552
-
Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations
-
Jordan MA, Toso RJ, Thrower D and Wilson L (1993) Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc Natl Acad Sci USA 90:9552-9556.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 9552-9556
-
-
Jordan, M.A.1
Toso, R.J.2
Thrower, D.3
Wilson, L.4
-
14
-
-
0030020158
-
Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death
-
Jordan MA, Wendell K, Gardiner S, Derry WB, Copp H and Wilson L (1996) Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res 56:816-825.
-
(1996)
Cancer Res
, vol.56
, pp. 816-825
-
-
Jordan, M.A.1
Wendell, K.2
Gardiner, S.3
Derry, W.B.4
Copp, H.5
Wilson, L.6
-
16
-
-
0029044165
-
Faclitaxel pharmacokinetics and pharmacodynamics
-
Kearns CM, Gianni L and Egorin MJ (1995) Faclitaxel pharmacokinetics and pharmacodynamics. Sem Oncol 22(Suppl 6):16-23.
-
(1995)
Sem Oncol
, vol.22
, Issue.SUPPL. 6
, pp. 16-23
-
-
Kearns, C.M.1
Gianni, L.2
Egorin, M.J.3
-
17
-
-
0002358219
-
Extracellular matrix regulation of growth and gene expression
-
Kleinman H (1990) Extracellular matrix regulation of growth and gene expression. Proc Am Assoc Cancer Res 31:490-491.
-
(1990)
Proc Am Assoc Cancer Res
, vol.31
, pp. 490-491
-
-
Kleinman, H.1
-
18
-
-
0029620911
-
Potential of the histoculture drug-response assay to contribute to cancer patient survival
-
Kubota T, Sasano N, Abe O, Nakao I, Kawamura E, Saito T, Endo M, Kimura K, Demura H, Sasano H, Nagura H, Ogawa N, Hoffman R and the Chemosensitivity Study Group for the Histoculture Drug-Response Assay (1995) Potential of the histoculture drug-response assay to contribute to cancer patient survival. Clin Cancer Res 1:1537-1543.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1537-1543
-
-
Kubota, T.1
Sasano, N.2
Abe, O.3
Nakao, I.4
Kawamura, E.5
Saito, T.6
Endo, M.7
Kimura, K.8
Demura, H.9
Sasano, H.10
Nagura, H.11
Ogawa, N.12
Hoffman, R.13
-
20
-
-
0027238859
-
Cell kill kinetics and cell cycle effects of taxol on human and hamster ovarian cell lines
-
Lopes NM, Adams EG, Pitts TW and Bhuyan BK (1993) Cell kill kinetics and cell cycle effects of taxol on human and hamster ovarian cell lines. Cancer Chemother Pharmacol 32:235-242.
-
(1993)
Cancer Chemother Pharmacol
, vol.32
, pp. 235-242
-
-
Lopes, N.M.1
Adams, E.G.2
Pitts, T.W.3
Bhuyan, B.K.4
-
22
-
-
0021266322
-
Penetration and binding of vinblastine and 5-fluorouracil in cellular spheroids
-
Nederman T and Carlsson J (1984) Penetration and binding of vinblastine and 5-fluorouracil in cellular spheroids. Cancer Chemother Pharmacol 13:131-135.
-
(1984)
Cancer Chemother Pharmacol
, vol.13
, pp. 131-135
-
-
Nederman, T.1
Carlsson, J.2
-
23
-
-
0023746784
-
Penetration of substances into tumor tissue - Model studies using saccharides, thymidine and thymidine-5′-triphosphate in cellular spheroids
-
Nederman T, Carlsson J and Kuoppa K (1988) Penetration of substances into tumor tissue - Model studies using saccharides, thymidine and thymidine-5′-triphosphate in cellular spheroids. Cancer Chemother Pharmacol 22:21-25.
-
(1988)
Cancer Chemother Pharmacol
, vol.22
, pp. 21-25
-
-
Nederman, T.1
Carlsson, J.2
Kuoppa, K.3
-
24
-
-
0019800854
-
Penetration of substances into tumor tissue: A methodological study on cellular spheroids
-
Nederman T, Carlsson J and Malmqvist M (1981) Penetration of substances into tumor tissue: A methodological study on cellular spheroids. In Vitro 17:290-298.
-
(1981)
In Vitro
, vol.17
, pp. 290-298
-
-
Nederman, T.1
Carlsson, J.2
Malmqvist, M.3
-
25
-
-
0030742692
-
Influence of drug exposure parameters on the activity of paclitaxel in multicellular spheroids
-
Nicholson KM, Bibby MC and Phillips RM (1997) Influence of drug exposure parameters on the activity of paclitaxel in multicellular spheroids. Eur J Cancer 33: 1291-1298.
-
(1997)
Eur J Cancer
, vol.33
, pp. 1291-1298
-
-
Nicholson, K.M.1
Bibby, M.C.2
Phillips, R.M.3
-
26
-
-
0019859353
-
Taxol binds to polymerized tubulin in vitro
-
Parness J and Horwitz SB (1981) Taxol binds to polymerized tubulin in vitro. J Cell Biol 91:479-487.
-
(1981)
J Cell Biol
, vol.91
, pp. 479-487
-
-
Parness, J.1
Horwitz, S.B.2
-
27
-
-
0027212626
-
Detection of p-glycoprotein with four monoclonal antibodies in normal and tumor tissues
-
Pavelic ZP, Reising J, Pavelic L, Kelley DJ, Stambrook PJ and Gluckman JL (1993) Detection of p-glycoprotein with four monoclonal antibodies in normal and tumor tissues. Arch Otolaryngol Head Neck Surg 119:753-757.
-
(1993)
Arch Otolaryngol Head Neck Surg
, vol.119
, pp. 753-757
-
-
Pavelic, Z.P.1
Reising, J.2
Pavelic, L.3
Kelley, D.J.4
Stambrook, P.J.5
Gluckman, J.L.6
-
28
-
-
0023199652
-
Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium
-
Ringel I and Horwitz SB (1987) Taxol is converted to 7-epitaxol, a biologically active isomer, in cell culture medium. J Pharmacol Exp Ther 242:692-698.
-
(1987)
J Pharmacol Exp Ther
, vol.242
, pp. 692-698
-
-
Ringel, I.1
Horwitz, S.B.2
-
29
-
-
0000076620
-
Cellular uptake and efflux of docetaxel (taxotere) and paclitaxel (taxol) in P388 cell line
-
Riou JF, Retitgenet O, Combeau C and Lavelle F (1994) Cellular uptake and efflux of docetaxel (taxotere) and paclitaxel (taxol) in P388 cell line. Proc Am Assoc Cancer Res 35:160.
-
(1994)
Proc Am Assoc Cancer Res
, vol.35
, pp. 160
-
-
Riou, J.F.1
Retitgenet, O.2
Combeau, C.3
Lavelle, F.4
-
30
-
-
0028230343
-
Sponge-gel-supported histoculture drug-response assay for head and neck cancer
-
Robbins KT, Connors KM, Storniolo AM, Hanchett C and Hoffman RM (1994) Sponge-gel-supported histoculture drug-response assay for head and neck cancer. Arch Otolaryngol Head Neck Surg 120:288-292.
-
(1994)
Arch Otolaryngol Head Neck Surg
, vol.120
, pp. 288-292
-
-
Robbins, K.T.1
Connors, K.M.2
Storniolo, A.M.3
Hanchett, C.4
Hoffman, R.M.5
-
31
-
-
0027787755
-
Taxol: Pharmacology, metabolism and clinical implications
-
Rowinsky EK, Wright M, Monsarrat B, Lesser GJ and Donehower RC (1993) Taxol: Pharmacology, metabolism and clinical implications. Cancer Surveys 17:283-301.
-
(1993)
Cancer Surveys
, vol.17
, pp. 283-301
-
-
Rowinsky, E.K.1
Wright, M.2
Monsarrat, B.3
Lesser, G.J.4
Donehower, R.C.5
-
32
-
-
0021972001
-
A phosphoglycoprotein associated with taxol-resistance in J774.2 cells
-
Roy S and Horwitz SB (1985) A phosphoglycoprotein associated with taxol-resistance in J774.2 cells. Cancer Res 45:3856-3865.
-
(1985)
Cancer Res
, vol.45
, pp. 3856-3865
-
-
Roy, S.1
Horwitz, S.B.2
-
33
-
-
0029173748
-
Paclitaxel metabolites in human plasma and urine: Identification of 6α-hydroxytaxol, 7-epitaxol and taxol hydrolysis products using liquid chromatography/ atmospheric-pressure chemical ionization mass spectrometry
-
Royer I, Alvinerie P, Armand JP, Ho LK, Wright M and Monsarrat B (1995) Paclitaxel metabolites in human plasma and urine: Identification of 6α-hydroxytaxol, 7-epitaxol and taxol hydrolysis products using liquid chromatography/ atmospheric-pressure chemical ionization mass spectrometry. Rapid Commun Mass Spectrom 9:495-502.
-
(1995)
Rapid Commun Mass Spectrom
, vol.9
, pp. 495-502
-
-
Royer, I.1
Alvinerie, P.2
Armand, J.P.3
Ho, L.K.4
Wright, M.5
Monsarrat, B.6
-
34
-
-
0031020572
-
Paclitaxel-induced apoptosis in MCF7 breast cancer cells
-
Saunders DE, Lawrence WD, Christensen C, Wappler ML, Ruan H and Deppe G (1997) Paclitaxel-induced apoptosis in MCF7 breast cancer cells. Int J Cancer 70:214-220.
-
(1997)
Int J Cancer
, vol.70
, pp. 214-220
-
-
Saunders, D.E.1
Lawrence, W.D.2
Christensen, C.3
Wappler, M.L.4
Ruan, H.5
Deppe, G.6
-
35
-
-
0025893114
-
Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies
-
Schinkel AH, Roelofs MEM, and Borst P (1991) Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies. Cancer Res 51:2628-2635.
-
(1991)
Cancer Res
, vol.51
, pp. 2628-2635
-
-
Schinkel, A.H.1
Roelofs, M.E.M.2
Borst, P.3
-
36
-
-
0017809904
-
Permeability of interstitial space of muscle (rat diaphragm) to solutes of different molecular weights
-
Schultz JS and Armstrong W (1978) Permeability of interstitial space of muscle (rat diaphragm) to solutes of different molecular weights. J Pharm Sci 67:696-700.
-
(1978)
J Pharm Sci
, vol.67
, pp. 696-700
-
-
Schultz, J.S.1
Armstrong, W.2
-
37
-
-
0028217279
-
P-glycoprotein binding and modulation of the multidrug resistant phenotype by estramustine
-
Speicher LA, Barone LR, Chapman AE, Hudes GR, Laing N, Smith CD and Tew KD (1994) P-glycoprotein binding and modulation of the multidrug resistant phenotype by estramustine. J Natl Cancer Inst 88:688-694.
-
(1994)
J Natl Cancer Inst
, vol.88
, pp. 688-694
-
-
Speicher, L.A.1
Barone, L.R.2
Chapman, A.E.3
Hudes, G.R.4
Laing, N.5
Smith, C.D.6
Tew, K.D.7
-
38
-
-
0028179167
-
New immunohistochemical "sandwich" staining method for mdr1 P-glycoprotein detection with JSB-1 monoclonal antibody in formalin-fixed, paraffin-embedded human tissues
-
Toth K, Vaughan MM, Slocum HK, Arredondo MA, Takita H, Baker RM and Rustum YM (1994) New immunohistochemical "sandwich" staining method for mdr1 P-glycoprotein detection with JSB-1 monoclonal antibody in formalin-fixed, paraffin-embedded human tissues. Am J Pathol 144:227-236.
-
(1994)
Am J Pathol
, vol.144
, pp. 227-236
-
-
Toth, K.1
Vaughan, M.M.2
Slocum, H.K.3
Arredondo, M.A.4
Takita, H.5
Baker, R.M.6
Rustum, Y.M.7
|