Mitigation of radiation-induced hematopoietic injury via regulation of cellular MAPK/phosphatase levels and increasing hematopoietic stem cells

Free Radical Biology and Medicine

Volumn 68, Issue , 2014, Pages 52-64

  Patwardhan, R S ^a   Sharma, Deepak ^a   Checker, Rahul ^a   Sandur, Santosh K ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

Baicalein; ERK; Free radicals; MKP3; Nrf 2; Radioprotector; Stem cells

Indexed keywords

BAICALEIN; HEME OXYGENASE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MKP3 PHOSPHATASE; PHOSPHATASE; RETINOIC ACID; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL ASSAY; CELL COUNT; CELL DEATH; CELL LEVEL; CELL NUCLEUS; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HEMATOLOGIC DISEASE; HEMATOPOIETIC STEM CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; IONIZING RADIATION; MALE; MORTALITY; MOUSE; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION INJURY; RADIATION PROTECTION; SIDE POPULATION CELL; SPLEEN LYMPHOCYTE; WHOLE BODY RADIATION;

BAICALEIN; ERK; FREE RADICALS; MKP3; NRF-2; RADIOPROTECTOR; STEM CELLS;

ANIMALS; ANTIOXIDANTS; CELL DEATH; DUAL SPECIFICITY PHOSPHATASE 6; FLAVANONES; HEMATOPOIETIC STEM CELLS; HEMATOPOIETIC SYSTEM; LYMPHOCYTES; MAP KINASE SIGNALING SYSTEM; MICE; NF-E2-RELATED FACTOR 2; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; WHOLE-BODY IRRADIATION;

EID: 84890960096     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.11.004     Document Type: Article

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