Tie21 bone marrow endothelial cells regulate hematopoietic stem cell regeneration following radiation injury

Stem Cells

Volumn 31, Issue 2, 2013, Pages 327-337

  Doan, Phuong L ^a   Russell, J Lauren ^a,b   Himburg, Heather A ^b   Helms, Katherine ^b   Harris, Jeffrey R ^c   Lucas, Joseph ^c   Holshausen, Kirsten C ^c,d   Meadows, Sarah K ^c   Daher, Pamela ^c   Jeffords, Laura B ^d   Chao, Nelson J ^b,d   Kirsch, David G ^a,c   Chute, John P ^d  

^a Department of Medicine   (United States)

^b DUKE UNIVERSITY   (United States)

^c Department of Radiation Oncology ^*  (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Endothelial cell; Hematopoietic stem cells; Irradiation; Stem cell microenvironment interactions

Indexed keywords

ANGIOPOIETIN RECEPTOR; CD45 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; PROTEIN BAK; PROTEIN BAX; VASCULAR ENDOTHELIAL CADHERIN; BAK1 PROTEIN, MOUSE; BAX PROTEIN, MOUSE; CADHERIN; PROTEIN TYROSINE KINASE; TEK PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; BONE MARROW SUPPRESSION; CELL REGENERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; GENETIC MODEL; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC SYSTEM; IONIZING RADIATION; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN EXPRESSION; RADIATION INJURY; RADIATION PROTECTION; VASCULARIZATION; WHOLE BODY RADIATION; ANIMAL; ENDOTHELIUM CELL; GENE EXPRESSION; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; METABOLISM; MORTALITY; PATHOLOGY; RADIATION EXPOSURE; REGENERATION; SIGNAL TRANSDUCTION; SURVIVAL; TRANSGENIC MOUSE;

ANIMALS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BONE MARROW CELLS; CADHERINS; ENDOTHELIAL CELLS; GENE EXPRESSION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MICE; MICE, TRANSGENIC; RADIATION INJURIES, EXPERIMENTAL; RECEPTOR PROTEIN-TYROSINE KINASES; REGENERATION; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; WHOLE-BODY IRRADIATION;

MLCS; MLOWN;

EID: 84874327921     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1275     Document Type: Article

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