-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal, A.; Bray, F.; Center, M. M.; Ferlay, J.; Ward, E.; Forman, D. Global cancer statistics. CA Cancer J. Clin. 2011, 61(2), 69-90.
-
(2011)
CA Cancer J. Clin.
, vol.61
, Issue.2
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
84855792427
-
Cancer statistics, 2012
-
Siegel, R.; Naishadham, D.; Jemal, A. Cancer statistics, 2012. CA Cancer J. Clin. 2012, 62(1), 10-29.
-
(2012)
CA Cancer J. Clin.
, vol.62
, Issue.1
, pp. 10-29
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
3
-
-
0028276423
-
Oncogene-induced basement membrane invasiveness in human mammary epithelial cells
-
Thompson, E. W.; Torri, J.; Sabol, M.; Sommers, C. L.; Byers, S.; Valverius, E. M.; Martin, G. R.; Lippman, M. E.; Stampfer, M. R.; Dickson, R. B. Oncogene-induced basement membrane invasiveness in human mammary epithelial cells. Clin. Exp. Metastasis 1994, 12(3), 181-194.
-
(1994)
Clin. Exp. Metastasis
, vol.12
, Issue.3
, pp. 181-194
-
-
Thompson, E.W.1
Torri, J.2
Sabol, M.3
Sommers, C.L.4
Byers, S.5
Valverius, E.M.6
Martin, G.R.7
Lippman, M.E.8
Stampfer, M.R.9
Dickson, R.B.10
-
4
-
-
0028317081
-
Modulations of the epithelial phenotype during embryogenesis and cancer progression
-
Savagner, P.; Boyer, B.; Valles, A. M.; Jouanneau, J.; Thiery, J. P. Modulations of the epithelial phenotype during embryogenesis and cancer progression. Cancer Treat. Res. 1994, 71, 229-249.
-
(1994)
Cancer Treat. Res.
, vol.71
, pp. 229-249
-
-
Savagner, P.1
Boyer, B.2
Valles, A.M.3
Jouanneau, J.4
Thiery, J.P.5
-
5
-
-
29844454865
-
Emerging role of KLF4 in human gastrointestinal cancer
-
Wei, D.; Kanai, M.; Huang, S.; Xie, K. Emerging role of KLF4 in human gastrointestinal cancer. Carcinogenesis 2006, 27(1), 23-31.
-
(2006)
Carcinogenesis
, vol.27
, Issue.1
, pp. 23-31
-
-
Wei, D.1
Kanai, M.2
Huang, S.3
Xie, K.4
-
6
-
-
53549133947
-
NCAM-induced focal adhesion assembly: A functional switch upon loss of E-cadherin
-
Lehembre, F.; Yilmaz, M.; Wicki, A. Schomber, T.; Strittmatter, K.; Ziegler, D.; Kren, A.; Went, P.; Derksen, P. W.; Berns, A.; Jonkers, J.; Christofori, G. NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherin. EMBO J. 2008, 27(19), 2603-2615.
-
(2008)
EMBO J.
, vol.27
, Issue.19
, pp. 2603-2615
-
-
Lehembre, F.1
Yilmaz, M.2
Wicki, A.3
Schomber, T.4
Strittmatter, K.5
Ziegler, D.6
Kren, A.7
Went, P.8
Derksen, P.W.9
Berns, A.10
Jonkers, J.11
Christofori, G.12
-
7
-
-
0024470390
-
Induction of an epithelialmesenchymal transition by an in vivo adheron-like complex
-
Mjaatvedt, C. H.; Markwald, R. R. Induction of an epithelialmesenchymal transition by an in vivo adheron-like complex. Dev. Biol. 1989, 136(1), 118-128.
-
(1989)
Dev. Biol.
, vol.136
, Issue.1
, pp. 118-128
-
-
Mjaatvedt, C.H.1
Markwald, R.R.2
-
8
-
-
84871151974
-
The EMT signaling pathways in endometrial carcinoma
-
Colas, E.; Pedrola, N.; Devis, L. Ertekin, T.; Campoy, I.; Martínez, E.; Llauradó, M.; Rigau, M.; Olivan, M.; Garcia, M.; Cabrera, S.; Gil-Moreno, A.; Xercavins, J.; Castellvi, J.; Garcia, A.; Ramon y Cajal, S.; Moreno-Bueno, G.; Dolcet, X.; Alameda, F.; Palacios, J.; Prat, J.; Doll, A.; Matias-Guiu, X.; Abal, M.; Reventos, J. The EMT signaling pathways in endometrial carcinoma. Clin. Transl. Oncol. 2012, 14(10), 715-720.
-
(2012)
Clin. Transl. Oncol.
, vol.14
, Issue.10
, pp. 715-720
-
-
Colas, E.1
Pedrola, N.2
Devis, L.3
Ertekin, T.4
Campoy, I.5
Martínez, E.6
Llauradó, M.7
Rigau, M.8
Olivan, M.9
Garcia, M.10
Cabrera, S.11
Gil-Moreno, A.12
Xercavins, J.13
Castellvi, J.14
Garcia, A.15
Ramon y Cajal, S.16
Moreno-Bueno, G.17
Dolcet, X.18
Alameda, F.19
Palacios, J.20
Prat, J.21
Doll, A.22
Matias-Guiu, X.23
Abal, M.24
Reventos, J.25
more..
-
9
-
-
84862770017
-
Regulation of EMT by TGFbeta in cancer
-
Heldin, C. H.; Vanlandewijck, M.; Moustakas, A. Regulation of EMT by TGFbeta in cancer. FEBS Lett. 2012, 586(14), 1959-1970.
-
(2012)
FEBS Lett.
, vol.586
, Issue.14
, pp. 1959-1970
-
-
Heldin, C.H.1
Vanlandewijck, M.2
Moustakas, A.3
-
10
-
-
77953878405
-
Adherens junctions: From molecules to morphogenesis
-
Harris, T. J.; Tepass, U. Adherens junctions: from molecules to morphogenesis. Nat. Rev. Mol. Cell Biol. 2010, 11(7), 502-514.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, Issue.7
, pp. 502-514
-
-
Harris, T.J.1
Tepass, U.2
-
11
-
-
79961208848
-
Initial steps of metastasis: Cell invasion and endothelial transmigration
-
van Zijl, F.; Krupitza, G.; Mikulits, W. Initial steps of metastasis: cell invasion and endothelial transmigration. Mutat. Res. 2011, 728(1-2), 23-34.
-
(2011)
Mutat. Res.
, vol.728
, Issue.1-2
, pp. 23-34
-
-
van Zijl, F.1
Krupitza, G.2
Mikulits, W.3
-
12
-
-
84875621521
-
The prognostic value of E-cadherin in gastric cancer: A meta-analysis
-
Xing, X.; Tang, Y. B.; Yuan, G.; Wang, Y.; Wang, J.; Yang, Y.; Chen, M. The prognostic value of E-cadherin in gastric cancer: a meta-analysis. Int. J. Cancer 2013, 132(11), 2589-2596.
-
(2013)
Int. J. Cancer
, vol.132
, Issue.11
, pp. 2589-2596
-
-
Xing, X.1
Tang, Y.B.2
Yuan, G.3
Wang, Y.4
Wang, J.5
Yang, Y.6
Chen, M.7
-
13
-
-
84892477219
-
The impact of E-cadherin expression on the prognosis of esophageal cancer: A meta-analysis
-
doi: 10.1111/dote.12024. [Epub ahead of print]
-
Xu, X. L.; Ling, Z. Q.; Chen, S. Z.; Li, B.; Ji, W. H.; Mao, W. M. The impact of E-cadherin expression on the prognosis of esophageal cancer: a meta-analysis. Dis Esophagus 2013. doi: 10.1111/dote.12024. [Epub ahead of print]
-
(2013)
Dis Esophagus
-
-
Xu, X.L.1
Ling, Z.Q.2
Chen, S.Z.3
Li, B.4
Ji, W.H.5
Mao, W.M.6
-
14
-
-
84864282082
-
Loss of E-cadherin promotes the growth, invasion and drug resistance of colorectal cancer cells and is associated with liver metastasis
-
Chen, X.; Wang, Y.; Xia, H.; Wang, Q.; Jiang, X.; Lin, Z.; Ma, Y.; Yang, Y.; Hu, M. Loss of E-cadherin promotes the growth, invasion and drug resistance of colorectal cancer cells and is associated with liver metastasis. Mol. Biol. Rep. 2012, 39(6), 6707-6714.
-
(2012)
Mol. Biol. Rep.
, vol.39
, Issue.6
, pp. 6707-6714
-
-
Chen, X.1
Wang, Y.2
Xia, H.3
Wang, Q.4
Jiang, X.5
Lin, Z.6
Ma, Y.7
Yang, Y.8
Hu, M.9
-
15
-
-
27944438391
-
E-cadherin and beta-catenin expression in normal, inflamed and cancerous gallbladder tissue
-
Puhalla, H.; Herberger, B.; Soleiman, A.; Filipits, M.; Laengle, F.; Gruenberger, T.; Wrba, F. E-cadherin and beta-catenin expression in normal, inflamed and cancerous gallbladder tissue. Anticancer Res. 2005, 25(6B), 4249-4254.
-
(2005)
Anticancer Res.
, vol.25
, Issue.6 B
, pp. 4249-4254
-
-
Puhalla, H.1
Herberger, B.2
Soleiman, A.3
Filipits, M.4
Laengle, F.5
Gruenberger, T.6
Wrba, F.7
-
16
-
-
84877046275
-
Altered distribution and expression pattern of E-cadherin in hepatocellular carcinomas: Correlations with prognosis and clinical features
-
Jiang, X. M.; Zhang, J. B.; Xiong, J.; Huang, X. X.; Ren, Z. G.; Altered distribution and expression pattern of E-cadherin in hepatocellular carcinomas: correlations with prognosis and clinical features. Asian Pac. J. Cancer Prev. 2012, 13(12), 6455-6461.
-
(2012)
Asian Pac. J. Cancer Prev.
, vol.13
, Issue.12
, pp. 6455-6461
-
-
Jiang, X.M.1
Zhang, J.B.2
Xiong, J.3
Huang, X.X.4
Ren, Z.G.5
-
17
-
-
0032410023
-
Aberrant E-cadherin expression associated with loss of differentiation and advanced stage in human pancreatic cancer
-
Karayiannakis, A. J.; Syrigos, K. N.; Chatzigianni, E.; Papanikolaou, S.; Alexiou, D.; Kalahanis, N.; Rosenberg, T.; Bastounis, E. Aberrant E-cadherin expression associated with loss of differentiation and advanced stage in human pancreatic cancer. Anticancer Res. 1998, 18(6A), 4177-4180.
-
(1998)
Anticancer Res.
, vol.18
, Issue.6 A
, pp. 4177-4180
-
-
Karayiannakis, A.J.1
Syrigos, K.N.2
Chatzigianni, E.3
Papanikolaou, S.4
Alexiou, D.5
Kalahanis, N.6
Rosenberg, T.7
Bastounis, E.8
-
18
-
-
5444267235
-
N-cadherin in the spotlight of cellcell adhesion, differentiation, embryogenesis, invasion and signalling
-
Derycke, L. D.; Bracke, M. E. N-cadherin in the spotlight of cellcell adhesion, differentiation, embryogenesis, invasion and signalling. Int. J. Dev. Biol. 2004, 48(5-6), 463-476.
-
(2004)
Int. J. Dev. Biol.
, vol.48
, Issue.5-6
, pp. 463-476
-
-
Derycke, L.D.1
Bracke, M.E.2
-
19
-
-
84863073614
-
A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis
-
Huang, C.; Qiu, Z.; Wang, L.; Peng, Z.; Jia, Z.; Logsdon, C. D.; Le, X.; Wei, D.; Huang, S.; Xie, K. A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis. Cancer Res. 2012, 72(3), 655-665.
-
(2012)
Cancer Res.
, vol.72
, Issue.3
, pp. 655-665
-
-
Huang, C.1
Qiu, Z.2
Wang, L.3
Peng, Z.4
Jia, Z.5
Logsdon, C.D.6
Le, X.7
Wei, D.8
Huang, S.9
Xie, K.10
-
20
-
-
33745297408
-
New signals from the invasive front
-
Christofori, G. New signals from the invasive front. Nature 2006, 441(7092), 444-450.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 444-450
-
-
Christofori, G.1
-
21
-
-
70450198396
-
Epithelialmesenchymal transitions in development and disease
-
Thiery, J. P.; Acloque, H.; Huang, R. Y.; Nieto, M. A. Epithelialmesenchymal transitions in development and disease. Cell 2009, 139(5), 871-890.
-
(2009)
Cell
, vol.139
, Issue.5
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
22
-
-
44449144396
-
Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
-
Yang, J.; Weinberg, R. A. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev. Cell 2008, 14(6), 818-829.
-
(2008)
Dev. Cell
, vol.14
, Issue.6
, pp. 818-829
-
-
Yang, J.1
Weinberg, R.A.2
-
23
-
-
79959559880
-
Role of Rho GTPases and their regulators in cancer progression
-
Rathinam, R.; Berrier, A.; Alahari, S. K. Role of Rho GTPases and their regulators in cancer progression. Front Biosci. 2011, 16, 2561-2571.
-
(2011)
Front Biosci.
, vol.16
, pp. 2561-2571
-
-
Rathinam, R.1
Berrier, A.2
Alahari, S.K.3
-
24
-
-
0035860820
-
Kruppel-like factors: Three fingers in many pies
-
Bieker, J. J. Kruppel-like factors: three fingers in many pies. J. Biol. Chem. 2001, 276(37), 34355-34358.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.37
, pp. 34355-34358
-
-
Bieker, J.J.1
-
25
-
-
0033178330
-
A tale of three fingers: The family of mammalian Sp/XKLF transcription factors
-
Philipsen, S.; Suske, G. A tale of three fingers: the family of mammalian Sp/XKLF transcription factors. Nucleic Acids Res. 1999, 27(15), 2991-3000.
-
(1999)
Nucleic Acids Res.
, vol.27
, Issue.15
, pp. 2991-3000
-
-
Philipsen, S.1
Suske, G.2
-
26
-
-
16244405603
-
Mammalian SP/KLF transcription factors: Bring in the family
-
Suske, G.; Bruford, E.; Philipsen, S. Mammalian SP/KLF transcription factors: bring in the family. Genomics 2005, 85(5), 551-556.
-
(2005)
Genomics
, vol.85
, Issue.5
, pp. 551-556
-
-
Suske, G.1
Bruford, E.2
Philipsen, S.3
-
27
-
-
0029829236
-
Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest
-
Shields, J. M.; Christy, R. J.; Yang, V. W. Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest. J. Biol. Chem. 1996, 271(33), 20009-20017.
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.33
, pp. 20009-20017
-
-
Shields, J.M.1
Christy, R.J.2
Yang, V.W.3
-
28
-
-
0029969727
-
A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells
-
Garrett-Sinha, L. A.; Eberspaecher, H.; Seldin, M. F.; de Crombrugghe, B. A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells. J. Biol. Chem. 1996, 271(49), 31384-31390.
-
(1996)
J. Biol. Chem.
, vol.271
, Issue.49
, pp. 31384-31390
-
-
Garrett-Sinha, L.A.1
Eberspaecher, H.2
Seldin, M.F.3
de Crombrugghe, B.4
-
29
-
-
0031594189
-
Human EZF, a Kruppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains
-
Yet, S. F.; McA'Nulty, M. M.; Folta, S. C.; Yen, H. W.; Yoshizumi, M.; Hsieh, C. M.; Layne, M. D.; Chin, M. T.; Wang, H.; Perrella, M. A.; Jain, M. K.; Lee, M. E. Human EZF, a Kruppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains. J. Biol Chem. 1998, 273(2), 1026-1031.
-
(1998)
J. Biol Chem.
, vol.273
, Issue.2
, pp. 1026-1031
-
-
Yet, S.F.1
McA'Nulty, M.M.2
Folta, S.C.3
Yen, H.W.4
Yoshizumi, M.5
Hsieh, C.M.6
Layne, M.D.7
Chin, M.T.8
Wang, H.9
Perrella, M.A.10
Jain, M.K.11
Lee, M.E.12
-
30
-
-
0032004389
-
Identification of the DNA sequence that interacts with the gut-enriched Kruppel-like factor
-
Shields, J. M.; Yang, V. W. Identification of the DNA sequence that interacts with the gut-enriched Kruppel-like factor. Nucleic Acids Res. 1998, 26(3), 796-802.
-
(1998)
Nucleic Acids Res.
, vol.26
, Issue.3
, pp. 796-802
-
-
Shields, J.M.1
Yang, V.W.2
-
31
-
-
0025264720
-
A novel cis-acting DNA element required for a high level of inducible expression of the rat P-450c gene
-
Yanagida, A.; Sogawa, K.; Yasumoto, K. I.; Fujii-Kuriyama, Y. A novel cis-acting DNA element required for a high level of inducible expression of the rat P-450c gene. Mol Cell Biol. 1990, 10(4), 1470-1475.
-
(1990)
Mol Cell Biol.
, vol.10
, Issue.4
, pp. 1470-1475
-
-
Yanagida, A.1
Sogawa, K.2
Yasumoto, K.I.3
Fujii-Kuriyama, Y.4
-
32
-
-
33646435815
-
KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells
-
Yang, Y.; Goldstein, B. G.; Chao, H. H.; Katz, J. P. KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells. Cancer Biol. Ther. 2005, 4(11), 1216-1221.
-
(2005)
Cancer Biol. Ther.
, vol.4
, Issue.11
, pp. 1216-1221
-
-
Yang, Y.1
Goldstein, B.G.2
Chao, H.H.3
Katz, J.P.4
-
33
-
-
0036901023
-
Down-regulation of gut-enriched Kruppel-like factor expression in esophageal cancer
-
Wang, N.; Liu, Z. H.; Ding, F.; Wang, X. Q.; Zhou, C. N.; Wu, M. Down-regulation of gut-enriched Kruppel-like factor expression in esophageal cancer. World J. Gastroenterol. 2002, 8(6), 966-970.
-
(2002)
World J. Gastroenterol.
, vol.8
, Issue.6
, pp. 966-970
-
-
Wang, N.1
Liu, Z.H.2
Ding, F.3
Wang, X.Q.4
Zhou, C.N.5
Wu, M.6
-
34
-
-
1442351994
-
Discovery of Ca2+-relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray
-
Luo, A.; Kong, J.; Hu, G. Liew, C. C.; Xiong, M.; Wang, X.; Ji, J.; Wang, T.; Zhi, H.; Wu, M.; Liu, Z. Discovery of Ca2+-relevant and differentiation-associated genes downregulated in esophageal squamous cell carcinoma using cDNA microarray. Oncogene 2004, 23(6), 1291-1299.
-
(2004)
Oncogene
, vol.23
, Issue.6
, pp. 1291-1299
-
-
Luo, A.1
Kong, J.2
Hu, G.3
Liew, C.C.4
Xiong, M.5
Wang, X.6
Ji, J.7
Wang, T.8
Zhi, H.9
Wu, M.10
Liu, Z.11
-
35
-
-
16844386207
-
Drastic down-regulation of Kruppellike factor 4 expression is critical in human gastric cancer development and progression
-
Wei, D.; Gong, W.; Kanai, M.; Schlunk, C.; Wang, L.; Yao, J. C.; Wu, T. T.; Huang, S.; Xie, K. Drastic down-regulation of Kruppellike factor 4 expression is critical in human gastric cancer development and progression. Cancer Res. 2005, 65(7), 2746-2754.
-
(2005)
Cancer Res.
, vol.65
, Issue.7
, pp. 2746-2754
-
-
Wei, D.1
Gong, W.2
Kanai, M.3
Schlunk, C.4
Wang, L.5
Yao, J.C.6
Wu, T.T.7
Huang, S.8
Xie, K.9
-
36
-
-
84863242777
-
Altered expression of Kruppel-like factor 4 and beta-catenin in human gastric cancer
-
Zhang, N.; Zhang, J.; Wang, Z. W.; Zha, L.; Huang, Z. Altered expression of Kruppel-like factor 4 and beta-catenin in human gastric cancer. Oncol. Lett. 2012, 3(5), 1017-1022.
-
(2012)
Oncol. Lett.
, vol.3
, Issue.5
, pp. 1017-1022
-
-
Zhang, N.1
Zhang, J.2
Wang, Z.W.3
Zha, L.4
Huang, Z.5
-
37
-
-
0034617495
-
Decreased expression of the gutenriched Kruppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients
-
Dang, D. T.; Bachman, K. E.; Mahatan, C. S.; Dang, L. H.; Giardiello, F. M.; Yang, V. W. Decreased expression of the gutenriched Kruppel-like factor gene in intestinal adenomas of multiple intestinal neoplasia mice and in colonic adenomas of familial adenomatous polyposis patients. FEBS Lett. 2000, 476(3), 203-207.
-
(2000)
FEBS Lett.
, vol.476
, Issue.3
, pp. 203-207
-
-
Dang, D.T.1
Bachman, K.E.2
Mahatan, C.S.3
Dang, L.H.4
Giardiello, F.M.5
Yang, V.W.6
-
38
-
-
33745964737
-
Altered expression of the KLF4 in colorectal cancers
-
Choi, B. J.; Cho, Y. G.; Song, J. W.; Kim, C. J.; Kim, S. Y.; Nam, S. W.; Yoo, N. J.; Lee, J. Y.; Park, W. S. Altered expression of the KLF4 in colorectal cancers. Pathol. Res. Pract. 2006, 202(8), 585-589.
-
(2006)
Pathol. Res. Pract.
, vol.202
, Issue.8
, pp. 585-589
-
-
Choi, B.J.1
Cho, Y.G.2
Song, J.W.3
Kim, C.J.4
Kim, S.Y.5
Nam, S.W.6
Yoo, N.J.7
Lee, J.Y.8
Park, W.S.9
-
39
-
-
77958044626
-
Expression of the tumor suppressor Kruppel-like factor 4 as a prognostic predictor for colon cancer
-
Patel, N. V.; Ghaleb, A. M.; Nandan, M. O.; Yang, V. W. Expression of the tumor suppressor Kruppel-like factor 4 as a prognostic predictor for colon cancer. Cancer Epidemiol. Biomarkers Prev. 2010, 19(10), 2631-2638.
-
(2010)
Cancer Epidemiol. Biomarkers Prev.
, vol.19
, Issue.10
, pp. 2631-2638
-
-
Patel, N.V.1
Ghaleb, A.M.2
Nandan, M.O.3
Yang, V.W.4
-
40
-
-
84865487198
-
DysregulatedKruppel-like factor 4 and vitamin D receptor signaling contribute to progression of hepatocellular carcinoma
-
Li, Q.; Gao, Y.; Jia, Z.; Mishra, L.; Guo, K.; Li, Z.; Le, X.; Wei, D.; Huang, S.; Xie, K. DysregulatedKruppel-like factor 4 and vitamin D receptor signaling contribute to progression of hepatocellular carcinoma. Gastroenterology 2012, 143(3), 799-810. e1-2.
-
(2012)
Gastroenterology
, vol.143
, Issue.3
-
-
Li, Q.1
Gao, Y.2
Jia, Z.3
Mishra, L.4
Guo, K.5
Li, Z.6
Le, X.7
Wei, D.8
Huang, S.9
Xie, K.10
-
41
-
-
0034674712
-
The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter
-
Zhang, W.; Geiman, D. E.; Shields, J. M.; Dang, D. T.; Mahatan, C. S.; Kaestner, K. H.; Biggs, J. R.; Kraft, A. S.; Yang, V. W. The gut-enriched Kruppel-like factor (Kruppel-like factor 4) mediates the transactivating effect of p53 on the p21WAF1/Cip1 promoter. J. Biol. Chem. 2000, 275(24), 18391-18398.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.24
, pp. 18391-18398
-
-
Zhang, W.1
Geiman, D.E.2
Shields, J.M.3
Dang, D.T.4
Mahatan, C.S.5
Kaestner, K.H.6
Biggs, J.R.7
Kraft, A.S.8
Yang, V.W.9
-
42
-
-
0031451645
-
Expression of the gut-enriched Kruppel-like factor gene during development and intestinal tumorigenesis
-
Ton-That, H.; Kaestner, K. H.; Shields, J. M.; Mahatanankoon, C. S.; Yang, V. W. Expression of the gut-enriched Kruppel-like factor gene during development and intestinal tumorigenesis. FEBS Lett. 1997, 419(2-3), 239-243.
-
(1997)
FEBS Lett.
, vol.419
, Issue.2-3
, pp. 239-243
-
-
Ton-That, H.1
Kaestner, K.H.2
Shields, J.M.3
Mahatanankoon, C.S.4
Yang, V.W.5
-
43
-
-
0037780740
-
Overexpression of Kruppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity
-
Dang, D. T.; Chen, X.; Feng, J.; Torbenson, M.; Dang, L. H.; Yang, V. W. Overexpression of Kruppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity. Oncogene 2003, 22(22), 3424-3430.
-
(2003)
Oncogene
, vol.22
, Issue.22
, pp. 3424-3430
-
-
Dang, D.T.1
Chen, X.2
Feng, J.3
Torbenson, M.4
Dang, L.H.5
Yang, V.W.6
-
44
-
-
84862777918
-
Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice
-
Li, Q.; Jia, Z.; Wang, L.; Kong, X.; Li, Q.; Guo, K.; Tan, D.; Le, X.; Wei, D.; Huang, S.; Mishra, L.; Xie, K. Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice. Gastroenterology 2012, 142(3), 531-542.
-
(2012)
Gastroenterology
, vol.142
, Issue.3
, pp. 531-542
-
-
Li, Q.1
Jia, Z.2
Wang, L.3
Kong, X.4
Li, Q.5
Guo, K.6
Tan, D.7
Le, X.8
Wei, D.9
Huang, S.10
Mishra, L.11
Xie, K.12
-
45
-
-
81055137232
-
FOXM1: From cancer initiation to progression and treatment
-
Koo, C. Y.; Muir, K. W.; Lam, E. W. FOXM1: From cancer initiation to progression and treatment. Biochim. Biophys. Acta 2012, 1819(1), 28-37.
-
(2012)
Biochim. Biophys. Acta
, vol.1819
, Issue.1
, pp. 28-37
-
-
Koo, C.Y.1
Muir, K.W.2
Lam, E.W.3
-
46
-
-
84880056261
-
Dysregulated expression of FOXM1 isoforms drive progression of pancreatic cancer
-
Kong, X.; Li, L.; Li, Z.; Le, X.; Huang, C.; Jia, Z.; Cui, J.; Huang, S.; Wang, L.; Xie, K. Dysregulated expression of FOXM1 isoforms drive progression of pancreatic cancer. Cancer Res. 2013, 73(13), 3987-3996.
-
(2013)
Cancer Res.
, vol.73
, Issue.13
, pp. 3987-3996
-
-
Kong, X.1
Li, L.2
Li, Z.3
Le, X.4
Huang, C.5
Jia, Z.6
Cui, J.7
Huang, S.8
Wang, L.9
Xie, K.10
-
47
-
-
17144401799
-
Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach
-
Katz, J. P.; Perreault, N.; Goldstein, B. G.; Actman, L.; McNally, S. R.; Silberg, D. G.; Furth, E. E.; Kaestner, K. H. Loss of Klf4 in mice causes altered proliferation and differentiation and precancerous changes in the adult stomach. Gastroenterology 2005, 128(4), 935-945.
-
(2005)
Gastroenterology
, vol.128
, Issue.4
, pp. 935-945
-
-
Katz, J.P.1
Perreault, N.2
Goldstein, B.G.3
Actman, L.4
McNally, S.R.5
Silberg, D.G.6
Furth, E.E.7
Kaestner, K.H.8
-
48
-
-
0036340041
-
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon
-
Katz, J. P.; Perreault, N.; Goldstein, B.G.; Lee, C. S.; Labosky, P. A.; Yang, V. W.; Kaestner, K. H. The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development 2002, 129(11), 2619-2628.
-
(2002)
Development
, vol.129
, Issue.11
, pp. 2619-2628
-
-
Katz, J.P.1
Perreault, N.2
Goldstein, B.G.3
Lee, C.S.4
Labosky, P.A.5
Yang, V.W.6
Kaestner, K.H.7
-
49
-
-
34547642699
-
Haploinsufficiency of Kruppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis
-
Ghaleb, A. M.; McConnell, B. B.;Nandan, M. O.; Katz, J. P.; Kaestner, K. H.; Yang, V. W. Haploinsufficiency of Kruppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis. Cancer Res. 2007, 67(15), 7147-7154.
-
(2007)
Cancer Res.
, vol.67
, Issue.15
, pp. 7147-7154
-
-
Ghaleb, A.M.1
McConnell, B.B.2
Nandan, M.O.3
Katz, J.P.4
Kaestner, K.H.5
Yang, V.W.6
-
50
-
-
77950877531
-
MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines
-
Tian, Y.; Luo, A.; Cai, Y.; Su, Q.; Ding, F.; Chen, H.; Liu, Z. MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines. J. Biol Chem. 2010, 285(11), 7986-7994.
-
(2010)
J. Biol Chem.
, vol.285
, Issue.11
, pp. 7986-7994
-
-
Tian, Y.1
Luo, A.2
Cai, Y.3
Su, Q.4
Ding, F.5
Chen, H.6
Liu, Z.7
-
51
-
-
0035833319
-
Expression of the gut-enriched Kruppel-like factor (Kruppellike factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2
-
Dang, D. T.; Mahatan, C. S.; Dang, L. H.; Agboola, I. A.; Yang, V. W. Expression of the gut-enriched Kruppel-like factor (Kruppellike factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2. Oncogene 2001, 20(35), 4884-4890.
-
(2001)
Oncogene
, vol.20
, Issue.35
, pp. 4884-4890
-
-
Dang, D.T.1
Mahatan, C.S.2
Dang, L.H.3
Agboola, I.A.4
Yang, V.W.5
-
52
-
-
0842329848
-
Identification of Kruppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer
-
Zhao, W.; Hisamuddin, I. M.; Nandan, M. O.; Babbin, B. A.; Lamb, N. E.; Yang, V. W. Identification of Kruppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer. Oncogene 2004, 23(2), 395-402.
-
(2004)
Oncogene
, vol.23
, Issue.2
, pp. 395-402
-
-
Zhao, W.1
Hisamuddin, I.M.2
Nandan, M.O.3
Babbin, B.A.4
Lamb, N.E.5
Yang, V.W.6
-
53
-
-
28544438941
-
Destabilization of Kruppel-like factor 4 protein in response to serum stimulation involves the ubiquitin-proteasome pathway
-
Chen, Z. Y.; Wang, X.; Zhou, Y.; Offner, G.; Tseng, C. C. Destabilization of Kruppel-like factor 4 protein in response to serum stimulation involves the ubiquitin-proteasome pathway. Cancer Res. 2005, 65(22), 10394-10400.
-
(2005)
Cancer Res.
, vol.65
, Issue.22
, pp. 10394-10400
-
-
Chen, Z.Y.1
Wang, X.2
Zhou, Y.3
Offner, G.4
Tseng, C.C.5
-
54
-
-
67649601502
-
Kruppel-like factor 4 represses transcription of the survivin gene in esophageal cancer cell lines
-
Zhang, G.; Zhu, H.; Wang, Y.; Yang, S.; Liu, M.; Zhang, W.; Quan, L.; Bai, J.; Liu, Z.; Xu, N. Kruppel-like factor 4 represses transcription of the survivin gene in esophageal cancer cell lines. Biol Chem. 2009, 390(5-6), 463-469.
-
(2009)
Biol Chem.
, vol.390
, Issue.5-6
, pp. 463-469
-
-
Zhang, G.1
Zhu, H.2
Wang, Y.3
Yang, S.4
Liu, M.5
Zhang, W.6
Quan, L.7
Bai, J.8
Liu, Z.9
Xu, N.10
-
55
-
-
79957889846
-
KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis
-
Li, D.; Peng, Z.; Tang, H.; Wei, P.; Kong, X.; Yan, D.; Huang, F.; Li, Q.; Le, X.; Li, Q.; Xie, K. KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis. Clin. Cancer Res. 2011, 17(11), 3558-3568.
-
(2011)
Clin. Cancer Res.
, vol.17
, Issue.11
, pp. 3558-3568
-
-
Li, D.1
Peng, Z.2
Tang, H.3
Wei, P.4
Kong, X.5
Yan, D.6
Huang, F.7
Li, Q.8
Le, X.9
Li, Q.10
Xie, K.11
-
56
-
-
84863050370
-
Regulation of the potential marker for intestinal cells, Bmi1, by beta-catenin and the zinc finger protein KLF4: Implications for colon cancer
-
Yu, T.; Chen, X.; Zhang, W.; Colon, D.; Shi, J.; Napier, D.; Rychahou, P.; Lu, W.; Lee, E. Y.; Weiss, H. L.; Evers, B. M.; Liu, C. Regulation of the potential marker for intestinal cells, Bmi1, by beta-catenin and the zinc finger protein KLF4: implications for colon cancer. J. Biol. Chem. 2012, 287(6), 3760-3768.
-
(2012)
J. Biol. Chem.
, vol.287
, Issue.6
, pp. 3760-3768
-
-
Yu, T.1
Chen, X.2
Zhang, W.3
Colon, D.4
Shi, J.5
Napier, D.6
Rychahou, P.7
Lu, W.8
Lee, E.Y.9
Weiss, H.L.10
Evers, B.M.11
Liu, C.12
-
57
-
-
0035839554
-
Kruppel-like factor 4 (gut-enriched Kruppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle
-
Chen, X.; Johns, D. C.; Geiman, D. E. Marban E, Dang DT, Hamlin G, Sun R, Yang VW. Kruppel-like factor 4 (gut-enriched Kruppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle. J. Biol. Chem. 2001, 276(32), 30423-30428.
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.32
, pp. 30423-30428
-
-
Chen, X.1
Johns, D.C.2
Geiman, D.E.3
Marban, E.4
Dang, D.T.5
Hamlin, G.6
Sun, R.7
Yang, V.W.8
-
58
-
-
0037462796
-
Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage
-
Yoon, H. S.; Chen, X.; Yang, V. W. Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. J. Biol. Chem. 2003, 278(4), 2101-2105.
-
(2003)
J. Biol. Chem.
, vol.278
, Issue.4
, pp. 2101-2105
-
-
Yoon, H.S.1
Chen, X.2
Yang, V.W.3
-
59
-
-
1042301369
-
Requirement of Kruppel-like factor 4 in preventing entry into mitosis following DNA damage
-
Yoon, H. S.; Yang, V. W. Requirement of Kruppel-like factor 4 in preventing entry into mitosis following DNA damage. J. Biol. Chem. 2004, 279(6), 5035-5041.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.6
, pp. 5035-5041
-
-
Yoon, H.S.1
Yang, V.W.2
-
60
-
-
60749109846
-
Cell cycle, CDKs and cancer: A changing paradigm
-
Malumbres, M.; Barbacid, M. Cell cycle, CDKs and cancer: a changing paradigm. Nat. Rev. Cancer 2009, 9(3), 153-166.
-
(2009)
Nat. Rev. Cancer
, vol.9
, Issue.3
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
61
-
-
0036314311
-
Redox-sensitive vascular smooth muscle cell proliferation is mediated by GKLF and Id3 in vitro and in vivo
-
Nickenig, G.; Baudler, S.; Muller, C.; Werner, C.; Werner, N.; Welzel, H.; Strehlow, K.; Böhm, M. Redox-sensitive vascular smooth muscle cell proliferation is mediated by GKLF and Id3 in vitro and in vivo. FASEB J. 2002, 16(9), 1077-1086.
-
(2002)
FASEB J.
, vol.16
, Issue.9
, pp. 1077-1086
-
-
Nickenig, G.1
Baudler, S.2
Muller, C.3
Werner, C.4
Werner, N.5
Welzel, H.6
Strehlow, K.7
Böhm, M.8
-
62
-
-
58149161379
-
Involvement of LF4 in sulforaphaneand iberin-mediated induction of p21(waf1/cip1)
-
Traka, M. H.; Chambers, K. F.; Lund, E. K.;Goodlad, R. A.; Johnson, I. T.;Mithen, R. F. Involvement of LF4 in sulforaphaneand iberin-mediated induction of p21(waf1/cip1). Nutr. Cancer 2009, 61(1), 137-145.
-
(2009)
Nutr. Cancer
, vol.61
, Issue.1
, pp. 137-145
-
-
Traka, M.H.1
Chambers, K.F.2
Lund, E.K.3
Goodlad, R.A.4
Johnson, I.T.5
Mithen, R.F.6
-
63
-
-
49649101156
-
Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells
-
Wei, D.; Kanai, M.; Jia, Z.; Le, X.; Xie, K. Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells. Cancer Res. 2008, 68(12), 4631-4639.
-
(2008)
Cancer Res.
, vol.68
, Issue.12
, pp. 4631-4639
-
-
Wei, D.1
Kanai, M.2
Jia, Z.3
Le, X.4
Xie, K.5
-
64
-
-
78649710595
-
KLF4alpha up-regulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer
-
Wei, D.; Wang, L.; Kanai, M.; Jia, Z.; Le, X.; Li, Q.; Wang, H.; Xie, K. KLF4alpha up-regulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer. Gastroenterology 2010, 139(6), 2135-2145.
-
(2010)
Gastroenterology
, vol.139
, Issue.6
, pp. 2135-2145
-
-
Wei, D.1
Wang, L.2
Kanai, M.3
Jia, Z.4
Le, X.5
Li, Q.6
Wang, H.7
Xie, K.8
-
65
-
-
0034238112
-
Gutenriched Kruppel-like factor represses cyclin D1 promoter activity through Sp1 motif
-
Shie, J. L.; Chen, Z. Y.; Fu, M.; Pestell, R. G.; Tseng, C. C. Gutenriched Kruppel-like factor represses cyclin D1 promoter activity through Sp1 motif. Nucleic Acids Res. 2000, 28(15), 2969-2976.
-
(2000)
Nucleic Acids Res.
, vol.28
, Issue.15
, pp. 2969-2976
-
-
Shie, J.L.1
Chen, Z.Y.2
Fu, M.3
Pestell, R.G.4
Tseng, C.C.5
-
66
-
-
0037195422
-
Gut-enriched Kruppel-like factor represses ornithine decarboxylase gene expression and functions as checkpoint regulator in colonic cancer cells
-
Chen, Z. Y.; Shie, J. L.; Tseng, C. C. Gut-enriched Kruppel-like factor represses ornithine decarboxylase gene expression and functions as checkpoint regulator in colonic cancer cells. J. Biol. Chem. 2002, 277(48), 46831-46839.
-
(2002)
J. Biol. Chem.
, vol.277
, Issue.48
, pp. 46831-46839
-
-
Chen, Z.Y.1
Shie, J.L.2
Tseng, C.C.3
-
67
-
-
21244499737
-
Kruppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage
-
Yoon, H. S.; Ghaleb, A. M.; Nandan, M. O.; Hisamuddin, I. M.; Dalton, W. B.; Yang, V. W. Kruppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage. Oncogene 2005, 24(25), 4017-4025.
-
(2005)
Oncogene
, vol.24
, Issue.25
, pp. 4017-4025
-
-
Yoon, H.S.1
Ghaleb, A.M.2
Nandan, M.O.3
Hisamuddin, I.M.4
Dalton, W.B.5
Yang, V.W.6
-
68
-
-
0033057439
-
Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: Transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF
-
Foster, K. W.; Ren, S.; Louro, I. D.; Lobo-Ruppert, S. M.; McKie-Bell, P.; Grizzle, W.; Hayes, M. R.; Broker, T. R.; Chow, L. T.; Ruppert, J. M. Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF. Cell Growth Differ. 1999, 10(6), 423-434.
-
(1999)
Cell Growth Differ.
, vol.10
, Issue.6
, pp. 423-434
-
-
Foster, K.W.1
Ren, S.2
Louro, I.D.3
Lobo-Ruppert, S.M.4
McKie-Bell, P.5
Grizzle, W.6
Hayes, M.R.7
Broker, T.R.8
Chow, L.T.9
Ruppert, J.M.10
-
69
-
-
0033693134
-
Increase of GKLF messenger RNA and protein expression during progression of breast cancer
-
Foster, K. W.; Frost, A. R.; McKie-Bell, P.; Lin, C. Y.; Engler, J. A.; Grizzle, W. E.; Ruppert, J. M. Increase of GKLF messenger RNA and protein expression during progression of breast cancer. Cancer Res. 2000, 60(22), 6488-6495.
-
(2000)
Cancer Res.
, vol.60
, Issue.22
, pp. 6488-6495
-
-
Foster, K.W.1
Frost, A.R.2
McKie-Bell, P.3
Lin, C.Y.4
Engler, J.A.5
Grizzle, W.E.6
Ruppert, J.M.7
-
70
-
-
11144358328
-
Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer
-
Pandya, A. Y.; Talley, L. I.; Frost, A. R.; Fitzgerald, T. J.; Trivedi, V.; Chakravarthy, M.; Chhieng, D. C.; Grizzle, W. E.; Engler, J. A.; Krontiras, H.; Bland, K. I.; LoBuglio, A. F.; Lobo-Ruppert, S. M.; Ruppert, J. M. Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer. Clin. Cancer Res. 2004, 10(8), 2709-2719.
-
(2004)
Clin. Cancer Res.
, vol.10
, Issue.8
, pp. 2709-2719
-
-
Pandya, A.Y.1
Talley, L.I.2
Frost, A.R.3
Fitzgerald, T.J.4
Trivedi, V.5
Chakravarthy, M.6
Chhieng, D.C.7
Grizzle, W.E.8
Engler, J.A.9
Krontiras, H.10
Bland, K.I.11
LoBuglio, A.F.12
Lobo-Ruppert, S.M.13
Ruppert, J.M.14
-
71
-
-
30144442965
-
KLF4, p21 and context-dependent opposing forces in cancer
-
Rowland, B. D.; Peeper, D. S. KLF4, p21 and context-dependent opposing forces in cancer. Nat. Rev. Cancer 2006, 6(1), 11-23.
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.1
, pp. 11-23
-
-
Rowland, B.D.1
Peeper, D.S.2
-
72
-
-
0032813661
-
Klf4 is a transcription factor required for establishing the barrier function of the skin
-
Segre, J. A.; Bauer, C.; Fuchs, E. Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat. Genet. 1999, 22(4), 356-360.
-
(1999)
Nat. Genet.
, vol.22
, Issue.4
, pp. 356-360
-
-
Segre, J.A.1
Bauer, C.2
Fuchs, E.3
-
73
-
-
0037459050
-
Transcriptional profiling of Kruppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation
-
Chen, X.; Whitney, E. M.; Gao, S. Y.; Yang, V. W. Transcriptional profiling of Kruppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation. J. Mol. Biol. 2003, 326(3), 665-677.
-
(2003)
J. Mol. Biol.
, vol.326
, Issue.3
, pp. 665-677
-
-
Chen, X.1
Whitney, E.M.2
Gao, S.Y.3
Yang, V.W.4
-
74
-
-
0032562575
-
Transactivation of the human keratin 4 and Epstein-Barr virus EDL2 promoters by gut-enriched Kruppel-like factor
-
Jenkins, T. D.; Opitz, O. G.; Okano, J.; Rustgi, A. K. Transactivation of the human keratin 4 and Epstein-Barr virus EDL2 promoters by gut-enriched Kruppel-like factor. J. Biol. Chem. 1998, 273(17), 10747-10754.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.17
, pp. 10747-10754
-
-
Jenkins, T.D.1
Opitz, O.G.2
Okano, J.3
Rustgi, A.K.4
-
75
-
-
0034623068
-
The tissue-dependent keratin 19 gene transcription is regulated by GKLF/KLF4 and Sp1
-
Brembeck, F. H.; Rustgi, A. K. The tissue-dependent keratin 19 gene transcription is regulated by GKLF/KLF4 and Sp1. J. Biol. Chem. 2000, 275(36), 28230-28239.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.36
, pp. 28230-28239
-
-
Brembeck, F.H.1
Rustgi, A.K.2
-
76
-
-
9144232988
-
Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched Kruppellike factor
-
Hinnebusch, B. F.; Siddique, A.; Henderson, J. W.; Malo, M. S.; Zhang, W.; Athaide, C. P.; Abedrapo, M. A.; Chen, X.; Yang, V. W.; Hodin, R. A. Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched Kruppellike factor. Am. J. Physiol. Gastrointest. Liver Physiol. 2004, 286(1), 23-30.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.286
, Issue.1
, pp. 23-30
-
-
Hinnebusch, B.F.1
Siddique, A.2
Henderson, J.W.3
Malo, M.S.4
Zhang, W.5
Athaide, C.P.6
Abedrapo, M.A.7
Chen, X.8
Yang, V.W.9
Hodin, R.A.10
-
77
-
-
56249119515
-
KLF4 regulation in intestinal epithelial cell maturation
-
Flandez, M.; Guilmeau, S.; Blache, P.; Augenlicht, L. H. KLF4 regulation in intestinal epithelial cell maturation. Exp. Cell Res. 2008, 314(20), 3712-3723.
-
(2008)
Exp. Cell Res.
, vol.314
, Issue.20
, pp. 3712-3723
-
-
Flandez, M.1
Guilmeau, S.2
Blache, P.3
Augenlicht, L.H.4
-
78
-
-
79960055909
-
Induced pluripotent stem cells: Opportunities and challenges
-
Okita, K.; Yamanaka, S. Induced pluripotent stem cells: opportunities and challenges. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 2011, 366(1575), 2198-2207.
-
(2011)
Philos. Trans. R. Soc. Lond. B. Biol. Sci.
, vol.366
, Issue.1575
, pp. 2198-2207
-
-
Okita, K.1
Yamanaka, S.2
-
79
-
-
84873903291
-
Kruppel-like factor 4 acts as an oncogene in colon cancer stem cell-enriched spheroid cells
-
Leng, Z.; Tao, K.; Xia, Q.; Tan, J.; Yue, Z.; Chen, J.; Xi, H.; Li, J.; Zheng, H. Kruppel-like factor 4 acts as an oncogene in colon cancer stem cell-enriched spheroid cells. PLoS One 2013, 8(2), e56082.
-
(2013)
PLoS One
, vol.8
, Issue.2
-
-
Leng, Z.1
Tao, K.2
Xia, Q.3
Tan, J.4
Yue, Z.5
Chen, J.6
Xi, H.7
Li, J.8
Zheng, H.9
-
80
-
-
84873050284
-
Regulatory networks defining EMT during cancer initiation and progression
-
De Craene, B.; Berx, G. Regulatory networks defining EMT during cancer initiation and progression. Nat. Rev. Cancer 2013, 13(2), 97-110.
-
(2013)
Nat. Rev. Cancer
, vol.13
, Issue.2
, pp. 97-110
-
-
De Craene, B.1
Berx, G.2
-
81
-
-
79960065994
-
Kruppellike factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer
-
Yori, J. L.; Seachrist, D. D.; Johnson, E.; Lozada, K. L.; Abdul-Karim, F. W.; Chodosh, L. A.; Schiemann, W. P.; Keri, R. A. Kruppellike factor 4 inhibits tumorigenic progression and metastasis in a mouse model of breast cancer. Neoplasia 2011, 13(7), 601-610.
-
(2011)
Neoplasia
, vol.13
, Issue.7
, pp. 601-610
-
-
Yori, J.L.1
Seachrist, D.D.2
Johnson, E.3
Lozada, K.L.4
Abdul-Karim, F.W.5
Chodosh, L.A.6
Schiemann, W.P.7
Keri, R.A.8
-
82
-
-
84865294024
-
Kruppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression
-
Lin, Z. S.; Chu, H. C.; Yen, Y. C.; Lewis, B. C.; Chen, Y. W. Kruppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression. PLoS One 2012, 7(8), e43593.
-
(2012)
PLoS One
, vol.7
, Issue.8
-
-
Lin, Z.S.1
Chu, H.C.2
Yen, Y.C.3
Lewis, B.C.4
Chen, Y.W.5
-
83
-
-
84874366011
-
Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8)
-
Tiwari, N.; Meyer-Schaller, N.; Arnold, P.; Antoniadis, H.; Pachkov, M.; van Nimwegen, E.; Christofori, G. Klf4 is a transcriptional regulator of genes critical for EMT, including Jnk1 (Mapk8). PLoS One 2013, 8(2), e57329.
-
(2013)
PLoS One
, vol.8
, Issue.2
-
-
Tiwari, N.1
Meyer-Schaller, N.2
Arnold, P.3
Antoniadis, H.4
Pachkov, M.5
van Nimwegen, E.6
Christofori, G.7
-
84
-
-
84875236715
-
Interplay between KLF4 and ZEB2/SIP1 in the regulation of Ecadherin expression
-
Koopmansch, B.; Berx, G.; Foidart, J. M.; Gilles, C.; Winkler, R. Interplay between KLF4 and ZEB2/SIP1 in the regulation of Ecadherin expression. Biochem. Biophys. Res. Commun. 2013, 431(4), 652-657.
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.431
, Issue.4
, pp. 652-657
-
-
Koopmansch, B.1
Berx, G.2
Foidart, J.M.3
Gilles, C.4
Winkler, R.5
-
85
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li, R.; Liang, J.; Ni, S.; Zhou, T.; Qing, X.; Li, H.; He, W.; Chen, J.; Li, F.; Zhuang, Q.; Qin, B.; Xu, J.; Li, W.; Yang, J.; Gan, Y.; Qin, D.; Feng, S.; Song, H.; Yang, D.; Zhang, B.; Zeng, L.; Lai, L.; Esteban, M. A.; Pei, D. A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell. 2010, 7(1), 51-63.
-
(2010)
Cell Stem Cell.
, vol.7
, Issue.1
, pp. 51-63
-
-
Li, R.1
Liang, J.2
Ni, S.3
Zhou, T.4
Qing, X.5
Li, H.6
He, W.7
Chen, J.8
Li, F.9
Zhuang, Q.10
Qin, B.11
Xu, J.12
Li, W.13
Yang, J.14
Gan, Y.15
Qin, D.16
Feng, S.17
Song, H.18
Yang, D.19
Zhang, B.20
Zeng, L.21
Lai, L.22
Esteban, M.A.23
Pei, D.24
more..
-
86
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi, Y.; Massague, J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 2003, 113(6), 685-700.
-
(2003)
Cell
, vol.113
, Issue.6
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
87
-
-
84871948755
-
TGF-beta signaling and epithelial-mesenchymal transition in cancer progression
-
Katsuno, Y.; Lamouille, S.; Derynck, R. TGF-beta signaling and epithelial-mesenchymal transition in cancer progression. Curr. Opin. Oncol. 2013, 25(1), 76-84.
-
(2013)
Curr. Opin. Oncol.
, vol.25
, Issue.1
, pp. 76-84
-
-
Katsuno, Y.1
Lamouille, S.2
Derynck, R.3
-
88
-
-
84863160718
-
Critical and reciprocal regulation of KLF4 and SLUG in transforming growth factor beta-initiated prostate cancer epithelialmesenchymal transition
-
Liu, Y. N.; Abou-Kheir, W.; Yin, J. J.; Fang, L.; Hynes, P.; Casey, O.; Hu, D.; Wan, Y.; Seng, V.; Sheppard-Tillman, H.; Martin, P.; Kelly, K. Critical and reciprocal regulation of KLF4 and SLUG in transforming growth factor beta-initiated prostate cancer epithelialmesenchymal transition. Mol. Cell Biol. 2012, 32(5), 941-953.
-
(2012)
Mol. Cell Biol.
, vol.32
, Issue.5
, pp. 941-953
-
-
Liu, Y.N.1
Abou-Kheir, W.2
Yin, J.J.3
Fang, L.4
Hynes, P.5
Casey, O.6
Hu, D.7
Wan, Y.8
Seng, V.9
Sheppard-Tillman, H.10
Martin, P.11
Kelly, K.12
-
89
-
-
79953197943
-
Regulation of Kruppel-like factor 4 by the anaphase promoting complex pathway is involved in TGF-beta signaling
-
Hu, D.; Wan, Y. Regulation of Kruppel-like factor 4 by the anaphase promoting complex pathway is involved in TGF-beta signaling. J. Biol Chem. 2011, 286(9), 6890-6901.
-
(2011)
J. Biol Chem.
, vol.286
, Issue.9
, pp. 6890-6901
-
-
Hu, D.1
Wan, Y.2
-
90
-
-
77952941222
-
Kruppel-like factor 4 promotes differentiation by transforming growth factor-beta receptormediated Smad and p38 MAPK signaling in vascular smooth muscle cells
-
Li, H. X.; Han, M.; Bernier, M.; Zheng, B.; Sun, S. G.; Su, M.; Zhang, R.; Fu, J. R.; Wen, J. K. Kruppel-like factor 4 promotes differentiation by transforming growth factor-beta receptormediated Smad and p38 MAPK signaling in vascular smooth muscle cells. J. Biol Chem. 2010, 285(23), 17846-17856.
-
(2010)
J. Biol Chem.
, vol.285
, Issue.23
, pp. 17846-17856
-
-
Li, H.X.1
Han, M.2
Bernier, M.3
Zheng, B.4
Sun, S.G.5
Su, M.6
Zhang, R.7
Fu, J.R.8
Wen, J.K.9
-
91
-
-
80051532504
-
Down-regulation of Kruppellike factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4
-
Davis-Dusenbery, B. N.; Chan, M. C.; Reno, K. E.; Weisman, A. S.; Layne, M. D.; Lagna, G.; Hata, A. Down-regulation of Kruppellike factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4. J. Biol. Chem. 2011, 286(32), 28097-28110.
-
(2011)
J. Biol. Chem.
, vol.286
, Issue.32
, pp. 28097-28110
-
-
Davis-Dusenbery, B.N.1
Chan, M.C.2
Reno, K.E.3
Weisman, A.S.4
Layne, M.D.5
Lagna, G.6
Hata, A.7
-
92
-
-
77953523118
-
The role of Notch signaling pathway in epithelial-mesenchymal transition (EMT) during development and tumor aggressiveness
-
Wang, Z.; Li, Y.; Kong, D.; Sarkar, F. H. The role of Notch signaling pathway in epithelial-mesenchymal transition (EMT) during development and tumor aggressiveness. Curr. Drug Targets 2010, 11(6), 745-751.
-
(2010)
Curr. Drug Targets
, vol.11
, Issue.6
, pp. 745-751
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
Sarkar, F.H.4
-
93
-
-
9144246932
-
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation
-
Timmerman, L. A.; Grego-Bessa, J.; Raya, A.; Bertrán, E.; Pérez-Pomares, J. M.; Díez, J.; Aranda, S.; Palomo, S.; McCormick, F.; Izpisúa-Belmonte, J. C.; de la Pompa, J. L. Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation. Genes Dev. 2004, 18(1), 99-115.
-
(2004)
Genes Dev.
, vol.18
, Issue.1
, pp. 99-115
-
-
Timmerman, L.A.1
Grego-Bessa, J.2
Raya, A.3
Bertrán, E.4
Pérez-Pomares, J.M.5
Díez, J.6
Aranda, S.7
Palomo, S.8
McCormick, F.9
Izpisúa-Belmonte, J.C.10
de la Pompa, J.L.11
-
94
-
-
79958088926
-
Zebrafishkruppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages
-
Li, I. C.; Chan, C. T.; Lu, Y. F.; Wu, Y. T.; Chen, Y. C.; Li, G. B.; Lin, C. Y.; Hwang, S. P. Zebrafishkruppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages. PLoS One 2011, 6(6), e20974.
-
(2011)
PLoS One
, vol.6
, Issue.6
-
-
Li, I.C.1
Chan, C.T.2
Lu, Y.F.3
Wu, Y.T.4
Chen, Y.C.5
Li, G.B.6
Lin, C.Y.7
Hwang, S.P.8
-
95
-
-
77956405520
-
Differential control of Notch1 gene transcription by Klf4 and Sp3 transcription factors in normal versus cancer-derived keratinocytes
-
Lambertini, C.; Pantano, S.; Dotto, G. P. Differential control of Notch1 gene transcription by Klf4 and Sp3 transcription factors in normal versus cancer-derived keratinocytes. PLoS One 2010, 5(4), e10369.
-
(2010)
PLoS One
, vol.5
, Issue.4
-
-
Lambertini, C.1
Pantano, S.2
Dotto, G.P.3
-
96
-
-
73549085602
-
Epithelial transformation by KLF4 requires Notch1 but not canonical Notch1 signaling
-
Liu, Z.; Teng, L.; Bailey, S. K.; Frost, A. R.; Bland, K. I.; LoBuglio, A. F.; Ruppert, J. M.; Lobo-Ruppert, S. M. Epithelial transformation by KLF4 requires Notch1 but not canonical Notch1 signaling. Cancer Biol. Ther. 2009, 8(19), 1840-1851.
-
(2009)
Cancer Biol. Ther.
, vol.8
, Issue.19
, pp. 1840-1851
-
-
Liu, Z.1
Teng, L.2
Bailey, S.K.3
Frost, A.R.4
Bland, K.I.5
LoBuglio, A.F.6
Ruppert, J.M.7
Lobo-Ruppert, S.M.8
-
97
-
-
57749110620
-
Notch inhibits expression of the Kruppel-like factor 4 tumor suppressor in the intestinal epithelium
-
Ghaleb, A. M.; Aggarwal, G.; Bialkowska, A. B.; Nandan, M. O.; Yang, V. W. Notch inhibits expression of the Kruppel-like factor 4 tumor suppressor in the intestinal epithelium. Mol. Cancer Res. 2008, 6(12), 1920-1927.
-
(2008)
Mol. Cancer Res.
, vol.6
, Issue.12
, pp. 1920-1927
-
-
Ghaleb, A.M.1
Aggarwal, G.2
Bialkowska, A.B.3
Nandan, M.O.4
Yang, V.W.5
-
98
-
-
77957571588
-
The role of nutraceuticals in the regulation of Wnt and Hedgehog signaling in cancer
-
Sarkar, F. H.; Li, Y.; Wang, Z.; Kong, D. The role of nutraceuticals in the regulation of Wnt and Hedgehog signaling in cancer. Cancer Metastasis Rev. 2010, 29(3), 383-394.
-
(2010)
Cancer Metastasis Rev.
, vol.29
, Issue.3
, pp. 383-394
-
-
Sarkar, F.H.1
Li, Y.2
Wang, Z.3
Kong, D.4
-
99
-
-
68549106083
-
E-cadherin, betacatenin, and ZEB1 in malignant progression of cancer
-
Schmalhofer, O.; Brabletz, S.; Brabletz, T. E-cadherin, betacatenin, and ZEB1 in malignant progression of cancer. Cancer Metastasis Rev. 2009, 28(1-2), 151-166.
-
(2009)
Cancer Metastasis Rev.
, vol.28
, Issue.1-2
, pp. 151-166
-
-
Schmalhofer, O.1
Brabletz, S.2
Brabletz, T.3
-
100
-
-
84864507806
-
KLF4 and SOX9 transcription factors antagonize beta-catenin and inhibit TCF-activity in cancer cells
-
Sellak, H.; Wu, S.; Lincoln, T. M. KLF4 and SOX9 transcription factors antagonize beta-catenin and inhibit TCF-activity in cancer cells. Biochim. Biophys. Acta. 2012, 1823(10), 1666-1675.
-
(2012)
Biochim. Biophys. Acta.
, vol.1823
, Issue.10
, pp. 1666-1675
-
-
Sellak, H.1
Wu, S.2
Lincoln, T.M.3
-
101
-
-
0037163902
-
Gut-enriched Kruppel-like factor regulates colonic cell growth through APC/beta-catenin pathway
-
Stone, C. D.; Chen, Z. Y.; Tseng, C. C. Gut-enriched Kruppel-like factor regulates colonic cell growth through APC/beta-catenin pathway. FEBS Lett. 2002, 530(1-3), 147-152.
-
(2002)
FEBS Lett.
, vol.530
, Issue.1-3
, pp. 147-152
-
-
Stone, C.D.1
Chen, Z.Y.2
Tseng, C.C.3
-
102
-
-
33644776032
-
Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression
-
Zhang, W.; Chen, X.; Kato, Y.; Evans, P. M.; Yuan, S.; Yang, J.; Rychahou, P. G.; Yang, V. W.; He, X.; Evers, B. M.; Liu, C. Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression. Mol. Cell Biol. 2006, 26(6), 2055-2064.
-
(2006)
Mol. Cell Biol.
, vol.26
, Issue.6
, pp. 2055-2064
-
-
Zhang, W.1
Chen, X.2
Kato, Y.3
Evans, P.M.4
Yuan, S.5
Yang, J.6
Rychahou, P.G.7
Yang, V.W.8
He, X.9
Evers, B.M.10
Liu, C.11
-
103
-
-
73549104289
-
KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by betacatenin
-
Evans, P. M.; Chen, X.; Zhang, W.; Liu, C. KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by betacatenin. Mol Cell Biol. 2010, 30(2), 372-381.
-
(2010)
Mol Cell Biol.
, vol.30
, Issue.2
, pp. 372-381
-
-
Evans, P.M.1
Chen, X.2
Zhang, W.3
Liu, C.4
|