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Volumn 72, Issue 3, 2012, Pages 655-665

A novel FoxM1-caveolin signaling pathway promotes pancreatic cancer invasion and metastasis

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN 1; FORKHEAD TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXM1; UNCLASSIFIED DRUG;

EID: 84863073614     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-3102     Document Type: Article
Times cited : (158)

References (50)
  • 2
    • 45749089796 scopus 로고    scopus 로고
    • Metastatic pancreatic cancer 2008: Is the glass less empty?
    • DOI 10.1634/theoncologist.2007-0181
    • Nieto J, Grossbard ML, Kozuch P. Metastatic pancreatic cancer 2008: is the glass less empty. Oncologist 2008;13:562-76. (Pubitemid 351872873)
    • (2008) Oncologist , vol.13 , Issue.5 , pp. 562-576
    • Nieto, J.1    Grossbard, M.L.2    Kozuch, P.3
  • 3
    • 68049098322 scopus 로고    scopus 로고
    • Pancreatic cancer: Current and future treatment strategies
    • Pliarchopoulou K, Pectasides D. Pancreatic cancer: current and future treatment strategies. Cancer Treat Rev 2009;35:431-6.
    • (2009) Cancer Treat Rev , vol.35 , pp. 431-436
    • Pliarchopoulou, K.1    Pectasides, D.2
  • 4
    • 77949264996 scopus 로고    scopus 로고
    • Advanced pancreatic carcinoma: Current treatment and future challenges
    • Stathis A, Moore MJ. Advanced pancreatic carcinoma: current treatment and future challenges. Nat Rev Clin Oncol 2010;7:163-72.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 163-172
    • Stathis, A.1    Moore, M.J.2
  • 7
    • 79551537218 scopus 로고    scopus 로고
    • Src and caveolin-1 reciprocally regulate metastasis via a common downstream signaling pathway in bladder cancer
    • Thomas S, Overdevest JB, Nitz MD, Williams PD, Owens CR, Sanchez-Carbayo M, et al. Src and caveolin-1 reciprocally regulate metastasis via a common downstream signaling pathway in bladder cancer. Cancer Res 2011;71:832-41.
    • (2011) Cancer Res , vol.71 , pp. 832-841
    • Thomas, S.1    Overdevest, J.B.2    Nitz, M.D.3    Williams, P.D.4    Owens, C.R.5    Sanchez-Carbayo, M.6
  • 9
    • 0037083622 scopus 로고    scopus 로고
    • Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage
    • DOI 10.1002/cncr.10329
    • Kato K, Hida Y, Miyamoto M, Hashida H, Shinohara T, Itoh T, et al. Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage. Cancer 2002;94:929-33. (Pubitemid 34150846)
    • (2002) Cancer , vol.94 , Issue.4 , pp. 929-933
    • Kato, K.1    Hida, Y.2    Miyamoto, M.3    Hashida, H.4    Shinohara, T.5    Itoh, T.6    Okushiba, S.7    Kondo, S.8    Katoh, H.9
  • 10
    • 0036841790 scopus 로고    scopus 로고
    • Upregulated caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation
    • Ho CC, Huang PH, Huang HY, Chen YH, Yang PC, Hsu SM. Upregulated caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation. Am J Pathol 2002;161:1647-56.
    • (2002) Am J Pathol , vol.161 , pp. 1647-1656
    • Ho, C.C.1    Huang, P.H.2    Huang, H.Y.3    Chen, Y.H.4    Yang, P.C.5    Hsu, S.M.6
  • 12
    • 46949096082 scopus 로고    scopus 로고
    • Caveolin-1: A marker for pancreatic cancer diagnosis
    • DOI 10.1586/14737159.8.4.395
    • Tanase CP. Caveolin-1: a marker for pancreatic cancer diagnosis. Expert Rev Mol Diagn 2008;8:395-404. (Pubitemid 351962086)
    • (2008) Expert Review of Molecular Diagnostics , vol.8 , Issue.4 , pp. 395-404
    • Tanase, C.P.1
  • 13
    • 67749094835 scopus 로고    scopus 로고
    • Caveolin-1 overexpression correlates with tumour progression markers in pancreatic ductal adenocarcinoma
    • Tanase CP, Dima S, Mihai M, Raducan E, Nicolescu MI, Albulescu L, et al. Caveolin-1 overexpression correlates with tumour progression markers in pancreatic ductal adenocarcinoma. J Mol Histol 2009;40:23-9.
    • (2009) J Mol Histol , vol.40 , pp. 23-29
    • Tanase, C.P.1    Dima, S.2    Mihai, M.3    Raducan, E.4    Nicolescu, M.I.5    Albulescu, L.6
  • 16
    • 53649086945 scopus 로고    scopus 로고
    • Co-expression of fatty acid synthase and caveolin-1 in pancreatic ductal adenocarcinoma: Implications for tumor progression and clinical outcome
    • Witkiewicz AK, Nguyen KH, Dasgupta A, Kennedy EP, Yeo CJ, Lisanti MP, et al. Co-expression of fatty acid synthase and caveolin-1 in pancreatic ductal adenocarcinoma: implications for tumor progression and clinical outcome. Cell Cycle 2008;7:3021-5.
    • (2008) Cell Cycle , vol.7 , pp. 3021-3025
    • Witkiewicz, A.K.1    Nguyen, K.H.2    Dasgupta, A.3    Kennedy, E.P.4    Yeo, C.J.5    Lisanti, M.P.6
  • 17
    • 46649102319 scopus 로고    scopus 로고
    • Caveolin-1 up-regulation during epithelial to mesenchymal transition is mediated by focal adhesion kinase
    • Bailey KM, Liu J. Caveolin-1 up-regulation during epithelial to mesenchymal transition is mediated by focal adhesion kinase. J Biol Chem 2008;283:13714-24.
    • (2008) J Biol Chem , vol.283 , pp. 13714-13724
    • Bailey, K.M.1    Liu, J.2
  • 18
    • 63049137530 scopus 로고    scopus 로고
    • Differential expression of Caveolin-1 in hepatocellular carcinoma: Correlation with differentiation state, motility and invasion
    • Cokakli M, Erdal E, Nart D, Yilmaz F, Sagol O, Kilic M, et al. Differential expression of Caveolin-1 in hepatocellular carcinoma: correlation with differentiation state, motility and invasion. BMC Cancer 2009;9:65.
    • (2009) BMC Cancer , vol.9 , pp. 65
    • Cokakli, M.1    Erdal, E.2    Nart, D.3    Yilmaz, F.4    Sagol, O.5    Kilic, M.6
  • 19
    • 28544449224 scopus 로고    scopus 로고
    • Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase
    • DOI 10.1128/MCB.25.24.10875-10894.2005
    • Wang IC, Chen YJ, Hughes D, Petrovic V, Major ML, Park HJ, et al. Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. Mol Cell Biol 2005;25:10875-94. (Pubitemid 41747132)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.24 , pp. 10875-10894
    • Wang, I.-C.1    Chen, Y.-J.2    Hughes, D.3    Petrovic, V.4    Major, M.L.5    Park, H.J.6    Tan, Y.7    Ackerson, T.8    Costa, R.H.9
  • 20
    • 45849107632 scopus 로고    scopus 로고
    • FoxM1 inhibitors as potential anticancer drugs
    • DOI 10.1517/14728222.12.6.663
    • Gartel AL. FoxM1 inhibitors as potential anticancer drugs. Expert Opin Ther Targets 2008;12:663-5. (Pubitemid 351877295)
    • (2008) Expert Opinion on Therapeutic Targets , vol.12 , Issue.6 , pp. 663-665
    • Gartel, A.L.1
  • 22
    • 84860390076 scopus 로고    scopus 로고
    • Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells
    • Bao B, Wang Z, Ali S, Kong D, Banerjee S, Ahmad A, et al. Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. J Cell Biochem 2011;112:2296-306.
    • (2011) J Cell Biochem , vol.112 , pp. 2296-2306
    • Bao, B.1    Wang, Z.2    Ali, S.3    Kong, D.4    Banerjee, S.5    Ahmad, A.6
  • 23
    • 0018865225 scopus 로고
    • Human cell line (COLO 357) of metastatic pancreatic adenocarcinoma
    • DOI 10.1002/ijc.2910250507
    • Morgan RT, Woods LK, Moore GE, Quinn LA, McGavran L, Gordon SG. Human cell line (COLO 357) of metastatic pancreatic adenocarcinoma. Int J Cancer 1980;25:591-8. (Pubitemid 10156843)
    • (1980) International Journal of Cancer , vol.25 , Issue.5 , pp. 591-598
    • Morgan, R.T.1    Woods, L.K.2    Moore, G.E.3
  • 25
    • 0037468567 scopus 로고    scopus 로고
    • A novel model system for studying the double-edged roles of nitric oxide production in pancreatic cancer growth and metastasis
    • DOI 10.1038/sj.onc.1206386
    • Wang B, Wei D, Crum VE, Richardson EL, Xiong HH, Luo Y, et al. A novel model system for studying the double-edged roles of nitric oxide production in pancreatic cancer growth and metastasis. Oncogene 2003;22:1771-82. (Pubitemid 36513137)
    • (2003) Oncogene , vol.22 , Issue.12 , pp. 1771-1782
    • Wang, B.1    Wei, D.2    Crum, V.E.3    Richardson, E.L.4    Xiong, H.H.5    Luo, Y.6    Huang, S.7    Abbruzzese, J.L.8    Xie, K.9
  • 26
    • 33645734725 scopus 로고    scopus 로고
    • FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells
    • Liu M, Dai B, Kang SH, Ban K, Huang FJ, Lang FF, et al. FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells. Cancer Res 2006;66:3593-602.
    • (2006) Cancer Res , vol.66 , pp. 3593-3602
    • Liu, M.1    Dai, B.2    Kang, S.H.3    Ban, K.4    Huang, F.J.5    Lang, F.F.6
  • 27
    • 0033756726 scopus 로고    scopus 로고
    • Isoforms of caveolin-1 and caveolar structure
    • Fujimoto T, Kogo H, Nomura R, Une T. Isoforms of caveolin-1 and caveolar structure. J Cell Sci 2000;113:3509-17.
    • (2000) J Cell Sci , vol.113 , pp. 3509-3517
    • Fujimoto, T.1    Kogo, H.2    Nomura, R.3    Une, T.4
  • 28
    • 0039252798 scopus 로고    scopus 로고
    • P42/44MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase A signaling cascades transcriptionally down-regulates caveolin-1 promoter activity
    • Engelman JA, Zhang XL, Razani B, Pestell RG, Lisanti MP. p42/44MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase A signaling cascades transcriptionally down-regulates caveolin-1 promoter activity. J Biol Chem 1999;274:32333-41.
    • (1999) J Biol Chem , vol.274 , pp. 32333-32341
    • Engelman, J.A.1    Zhang, X.L.2    Razani, B.3    Pestell, R.G.4    Lisanti, M.P.5
  • 29
    • 65949124894 scopus 로고    scopus 로고
    • Critical role and regulation of transcription factor FoxM1 in human gastric cancer angiogenesis and progression
    • Li Q, Zhang N, Jia Z, Le X, Dai B, Wei D, et al. Critical role and regulation of transcription factor FoxM1 in human gastric cancer angiogenesis and progression. Cancer Res 2009;69:3501-9.
    • (2009) Cancer Res , vol.69 , pp. 3501-3509
    • Li, Q.1    Zhang, N.2    Jia, Z.3    Le, X.4    Dai, B.5    Wei, D.6
  • 31
    • 55349089547 scopus 로고    scopus 로고
    • FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells
    • Zhang Y, Zhang N, Dai B, Liu M, Sawaya R, Xie K, et al. FoxM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells. Cancer Res 2008;68:8733-42.
    • (2008) Cancer Res , vol.68 , pp. 8733-8742
    • Zhang, Y.1    Zhang, N.2    Dai, B.3    Liu, M.4    Sawaya, R.5    Xie, K.6
  • 33
    • 0032447249 scopus 로고    scopus 로고
    • Liver metastases are enhanced in homozygous deletionally mutant ICAM-1 or LFA-1 mice
    • DOI 10.1006/jsre.1998.5322
    • Marvin MR, Southall JC, Trokhan S, DeRosa C, Chabot J. Liver metastases are enhanced in homozygous deletionally mutant ICAM-1 or LFA-1 mice. J Surg Res 1998;80:143-8. (Pubitemid 29019661)
    • (1998) Journal of Surgical Research , vol.80 , Issue.2 , pp. 143-148
    • Marvin, M.R.1    Southall, J.C.2    Trokhan, S.3    Derosa, C.4    Chabot, J.5
  • 34
    • 33746255603 scopus 로고    scopus 로고
    • Despite its strong transactivation domain, transcription factor FOXM1c is kept almost inactive by two different inhibitory domains
    • DOI 10.1515/BC.2006.120, PII BCHM3877963
    • Wierstra I, Alves J. Despite its strong transactivation domain, transcription factor FOXM1c is kept almost inactive by two different inhibitory domains. Biol Chem 2006;387:963-76. (Pubitemid 44100243)
    • (2006) Biological Chemistry , vol.387 , Issue.7 , pp. 963-976
    • Wierstra, I.1    Alves, J.2
  • 35
    • 34548558343 scopus 로고    scopus 로고
    • Aberrant FoxM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells
    • DOI 10.1038/sj.onc.1210443, PII 1210443
    • Dai B, Kang SH, Gong W, Liu M, Aldape KD, Sawaya R, et al. Aberrant FoxM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells. Oncogene 2007;26:6212-9. (Pubitemid 47414378)
    • (2007) Oncogene , vol.26 , Issue.42 , pp. 6212-6219
    • Dai, B.1    Kang, S.-H.2    Gong, W.3    Liu, M.4    Aldape, K.D.5    Sawaya, R.6    Huang, S.7
  • 36
    • 49549094763 scopus 로고    scopus 로고
    • Caveolin-1: An ambiguous partner in cell signalling and cancer
    • Quest AF, Gutierrez-Pajares JL, Torres VA. Caveolin-1: an ambiguous partner in cell signalling and cancer. J Cell Mol Med 2008;12:1130-50.
    • (2008) J Cell Mol Med , vol.12 , pp. 1130-1150
    • Quest, A.F.1    Gutierrez-Pajares, J.L.2    Torres, V.A.3
  • 37
    • 0037018405 scopus 로고    scopus 로고
    • Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells
    • DOI 10.1038/sj/onc/1205300
    • Fiucci G, Ravid D, Reich R, Liscovitch M. Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells. Oncogene 2002;21:2365-75. (Pubitemid 34413560)
    • (2002) Oncogene , vol.21 , Issue.15 , pp. 2365-2375
    • Fiucci, G.1    Ravid, D.2    Reich, R.3    Liscovitch, M.4
  • 39
    • 39049089569 scopus 로고    scopus 로고
    • Caveolin-1 mediated expression and secretion of Kallikrein 6 in colon cancer cells
    • DOI 10.1593/neo.07817
    • Henkhaus RS, Roy UK, Cavallo-Medved D, Sloane BF, Gerner EW, Ignatenko NA. Caveolin-1-mediated expression and secretion of kallikrein 6 in colon cancer cells. Neoplasia 2008;10:140-8. (Pubitemid 351240880)
    • (2008) Neoplasia , vol.10 , Issue.2 , pp. 140-148
    • Henkhaus, R.S.1    Roy, U.K.B.2    Cavallo-Medved, D.3    Sloane, B.F.4    Gerner, E.W.5    Ignatenko, N.A.6
  • 40
    • 0028953271 scopus 로고
    • Reduction of caveolin and caveolae in oncogenically transformed cells
    • Koleske AJ, Baltimore D, Lisanti MP. Reduction of caveolin and caveolae in oncogenically transformed cells. Proc Natl Acad Sci U S A 1995;92:1381-5.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 1381-1385
    • Koleske, A.J.1    Baltimore, D.2    Lisanti, M.P.3
  • 41
    • 37549016730 scopus 로고    scopus 로고
    • Caveolin-1 expression is significantly associated with drug resistance and poor prognosis in advanced non-small cell lung cancer patients treated with gemcitabine-based chemotherapy
    • Ho CC, Kuo SH, Huang PH, Huang HY, Yang CH, Yang PC. Caveolin-1 expression is significantly associated with drug resistance and poor prognosis in advanced non-small cell lung cancer patients treated with gemcitabine-based chemotherapy. Lung Cancer 2008;59:105-10.
    • (2008) Lung Cancer , vol.59 , pp. 105-110
    • Ho, C.C.1    Kuo, S.H.2    Huang, P.H.3    Huang, H.Y.4    Yang, C.H.5    Yang, P.C.6
  • 42
    • 77049096710 scopus 로고    scopus 로고
    • Caveolin-1 regulating the invasion and expression of matrix metalloproteinase (MMPs) in pancreatic carcinoma cells
    • Han F, Zhu HG. Caveolin-1 regulating the invasion and expression of matrix metalloproteinase (MMPs) in pancreatic carcinoma cells. J Surg Res 2010;159:443-50.
    • (2010) J Surg Res , vol.159 , pp. 443-450
    • Han, F.1    Zhu, H.G.2
  • 43
    • 33646415976 scopus 로고    scopus 로고
    • Divergent expression and roles for caveolin-1 in mouse hepatocarcinoma cell lines with varying invasive ability
    • Zhou H, Jia L, Wang S, Wang H, Chu H, Hu Y, et al. Divergent expression and roles for caveolin-1 in mouse hepatocarcinoma cell lines with varying invasive ability. Biochem Biophys Res Commun 2006;345:486-94.
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 486-494
    • Zhou, H.1    Jia, L.2    Wang, S.3    Wang, H.4    Chu, H.5    Hu, Y.6
  • 44
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: Mechanistic insights and clinical challenges
    • DOI 10.1038/nm1469, PII NM1469
    • Steeg PS. Tumor metastasis: mechanistic insights and clinical challenges. Nat Med 2006;12:895-904. (Pubitemid 44175140)
    • (2006) Nature Medicine , vol.12 , Issue.8 , pp. 895-904
    • Steeg, P.S.1
  • 45
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science 2011;331:1559-64.
    • (2011) Science , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 47
    • 24644480749 scopus 로고    scopus 로고
    • Molecular requirements for epithelial-mesenchymal transition during tumor progression
    • DOI 10.1016/j.ceb.2005.08.001, PII S0955067405001043
    • Huber MA, Kraut N, Beug H. Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol 2005;17:548-58. (Pubitemid 41267170)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.5 SPEC. ISS. , pp. 548-558
    • Huber, M.A.1    Kraut, N.2    Beug, H.3
  • 48
    • 33845345975 scopus 로고    scopus 로고
    • Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elements
    • DOI 10.1158/0008-5472.CAN-06-1236
    • Dasari A, Bartholomew JN, Volonte D, Galbiati F. Oxidative stress induces premature senescence by stimulating caveolin-1 gene transcription through p38 mitogen-activated protein kinase/Sp1-mediated activation of two GC-rich promoter elements. Cancer Res 2006;66:10805-14. (Pubitemid 44876976)
    • (2006) Cancer Research , vol.66 , Issue.22 , pp. 10805-10814
    • Dasari, A.1    Bartholomew, J.N.2    Volonte, D.3    Galbiati, F.4
  • 49
    • 79960082255 scopus 로고    scopus 로고
    • Transcription factor Sp1 is essential for the regulation of the porcine caveolin-1 gene
    • Chen W, Chen Y, Qin L, Li A, Zhao X, Wang X, et al. Transcription factor Sp1 is essential for the regulation of the porcine caveolin-1 gene. DNA Cell Biol 2011;30:491-7.
    • (2011) DNA Cell Biol , vol.30 , pp. 491-497
    • Chen, W.1    Chen, Y.2    Qin, L.3    Li, A.4    Zhao, X.5    Wang, X.6
  • 50
    • 79960393173 scopus 로고    scopus 로고
    • Caveolin-1 upregulation mediates suppression of primary breast tumor growth and brain metastases by Stat3 inhibition
    • Chiu WT, Lee HT, Huang FJ, Aldape KD, Yao J, Steeg PS, et al. Caveolin-1 upregulation mediates suppression of primary breast tumor growth and brain metastases by Stat3 inhibition. Cancer Res 2011;71:4932-43.
    • (2011) Cancer Res , vol.71 , pp. 4932-4943
    • Chiu, W.T.1    Lee, H.T.2    Huang, F.J.3    Aldape, K.D.4    Yao, J.5    Steeg, P.S.6


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