메뉴 건너뛰기




Volumn 1823, Issue 10, 2012, Pages 1666-1675

KLF4 and SOX9 transcription factors antagonize β-catenin and inhibit TCF-activity in cancer cells

Author keywords

catenin; Cancer; KLF4; Sox9; T cell factor; Wnt signaling

Indexed keywords

BETA CATENIN; KRUPPEL LIKE FACTOR 4; LUCIFERASE; T CELL FACTOR PROTEIN; TRANSCRIPTION FACTOR SOX9;

EID: 84864507806     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2012.06.027     Document Type: Article
Times cited : (40)

References (49)
  • 1
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling in development and disease
    • (Review)
    • Clevers H. Wnt/β-catenin signaling in development and disease. Cell 2006, 27:469-480. (Review).
    • (2006) Cell , vol.27 , pp. 469-480
    • Clevers, H.1
  • 2
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling: components, mechanisms, and diseases
    • MacDonald B.T., Tamai K., He X. Wnt/β-catenin signaling: components, mechanisms, and diseases. Dev. Cell 2009, 17:9-26.
    • (2009) Dev. Cell , vol.17 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 3
    • 0034232066 scopus 로고    scopus 로고
    • Curbing the nuclear activities of β-Catenin control over Wnt target gene expression
    • Hecht A., Kemler R. Curbing the nuclear activities of β-Catenin control over Wnt target gene expression. EMBO Rep. 2001, 1:24-28.
    • (2001) EMBO Rep. , vol.1 , pp. 24-28
    • Hecht, A.1    Kemler, R.2
  • 4
    • 73549104289 scopus 로고    scopus 로고
    • KLF4 interacts with β-catenin/TCF4 and blocks p300/CBP recruitment by β-catenin
    • Evans P.M., Chen X., Zhang W., Liu C. KLF4 interacts with β-catenin/TCF4 and blocks p300/CBP recruitment by β-catenin. Mol. Cell. Biol. 2010, 30:372-381.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 372-381
    • Evans, P.M.1    Chen, X.2    Zhang, W.3    Liu, C.4
  • 5
    • 0036747385 scopus 로고    scopus 로고
    • The ins and outs of APC and β-catenin nuclear transport
    • (Review)
    • Henderson B.R., Fagotto F. The ins and outs of APC and β-catenin nuclear transport. EMBO Rep. 2002, 3:834-839. (Review).
    • (2002) EMBO Rep. , vol.3 , pp. 834-839
    • Henderson, B.R.1    Fagotto, F.2
  • 6
    • 0029829236 scopus 로고    scopus 로고
    • Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest
    • Shields J.M., Christy R.J., Yang V.W. Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest. J. Biol. Chem. 1996, 271:20009-20017.
    • (1996) J. Biol. Chem. , vol.271 , pp. 20009-20017
    • Shields, J.M.1    Christy, R.J.2    Yang, V.W.3
  • 7
    • 0032813661 scopus 로고    scopus 로고
    • Klf4 is a transcription factor required for establishing the barrier function of the skin
    • Serge J.A., Bauer C., Fuchs E. Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat. Genet. 1999, 22:356-360.
    • (1999) Nat. Genet. , vol.22 , pp. 356-360
    • Serge, J.A.1    Bauer, C.2    Fuchs, E.3
  • 10
    • 0032406715 scopus 로고    scopus 로고
    • Mechanisms of Wnt signaling in development
    • Wodarz A., Nusse R. Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 1998, 4:59-88.
    • (1998) Annu. Rev. Cell Dev. Biol. , vol.4 , pp. 59-88
    • Wodarz, A.1    Nusse, R.2
  • 11
    • 0035839554 scopus 로고    scopus 로고
    • Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle
    • Chen X., Johns D.C., Geiman D.E., Marban E., Dang D.T., Hamlin G., Sun R., Yang V.W. Krüppel-like factor 4 (gut-enriched Krüppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle. J. Biol. Chem. 2001, 276:30423-30428.
    • (2001) J. Biol. Chem. , vol.276 , pp. 30423-30428
    • Chen, X.1    Johns, D.C.2    Geiman, D.E.3    Marban, E.4    Dang, D.T.5    Hamlin, G.6    Sun, R.7    Yang, V.W.8
  • 12
    • 0842329848 scopus 로고    scopus 로고
    • Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer
    • Zhao W., Hisamuddin I.M., Nandan M.O., Babbin B.A., Lamb N.E., Yang V.W. Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer. Oncogene 2004, 2:395-402.
    • (2004) Oncogene , vol.2 , pp. 395-402
    • Zhao, W.1    Hisamuddin, I.M.2    Nandan, M.O.3    Babbin, B.A.4    Lamb, N.E.5    Yang, V.W.6
  • 13
    • 0037780740 scopus 로고    scopus 로고
    • Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenicity
    • Dang D.T., Chen X., Feng J., Torbenson M., Dang L.H., Yang V.W. Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenicity. Oncogene 2003, 22:3424-3430.
    • (2003) Oncogene , vol.22 , pp. 3424-3430
    • Dang, D.T.1    Chen, X.2    Feng, J.3    Torbenson, M.4    Dang, L.H.5    Yang, V.W.6
  • 14
    • 34547642699 scopus 로고    scopus 로고
    • Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis
    • Ghaleb A.M., McConnell B.B., Nandan M.O., Katz J.P., Kaestner K.H., Yang V.W. Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis. Cancer Res. 2007, 67:7147-7154.
    • (2007) Cancer Res. , vol.67 , pp. 7147-7154
    • Ghaleb, A.M.1    McConnell, B.B.2    Nandan, M.O.3    Katz, J.P.4    Kaestner, K.H.5    Yang, V.W.6
  • 15
    • 16844386207 scopus 로고    scopus 로고
    • Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression
    • Wei D., Gong W., Kanai M., Schlunk C., Wang L., Yao J.C., Wu T.T., Huang S., Xie K. Drastic down-regulation of Krüppel-like factor 4 expression is critical in human gastric cancer development and progression. Cancer Res. 2005, 65:2746-2754.
    • (2005) Cancer Res. , vol.65 , pp. 2746-2754
    • Wei, D.1    Gong, W.2    Kanai, M.3    Schlunk, C.4    Wang, L.5    Yao, J.C.6    Wu, T.T.7    Huang, S.8    Xie, K.9
  • 20
    • 0037163902 scopus 로고    scopus 로고
    • Gut-enriched Krüppel-like factor regulates colonic cell growth through APC/beta-catenin pathway
    • Stone C., Chen Z.Y., Tseng C.C. Gut-enriched Krüppel-like factor regulates colonic cell growth through APC/beta-catenin pathway. FEBS Lett. 2002, 530:147-152.
    • (2002) FEBS Lett. , vol.530 , pp. 147-152
    • Stone, C.1    Chen, Z.Y.2    Tseng, C.C.3
  • 21
  • 23
    • 73949105534 scopus 로고    scopus 로고
    • Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease
    • Kormish J.D., Sinner D., Zorn A.M. Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease. Dev. Dyn. 2010, 239:56-68.
    • (2010) Dev. Dyn. , vol.239 , pp. 56-68
    • Kormish, J.D.1    Sinner, D.2    Zorn, A.M.3
  • 26
    • 16844375712 scopus 로고    scopus 로고
    • Expression of the carcino-embryonic antigen gene is inhibited by SOX9 in human colon carcinoma cells
    • Jay P., Berta P., Blache P. Expression of the carcino-embryonic antigen gene is inhibited by SOX9 in human colon carcinoma cells. Cancer Res. 2005, 65:2193-2198.
    • (2005) Cancer Res. , vol.65 , pp. 2193-2198
    • Jay, P.1    Berta, P.2    Blache, P.3
  • 27
    • 3042670072 scopus 로고    scopus 로고
    • Suppression of growth and tumorigenicity in the prostate tumor cell line M12 by overexpression of the transcription factor SOX9
    • Drivdahl R., Haugk K.H., Sprenger C.C., Nelson P.S., Tennant M.K., Plymate S.R. Suppression of growth and tumorigenicity in the prostate tumor cell line M12 by overexpression of the transcription factor SOX9. Oncogene 2004, 23:4584-4593.
    • (2004) Oncogene , vol.23 , pp. 4584-4593
    • Drivdahl, R.1    Haugk, K.H.2    Sprenger, C.C.3    Nelson, P.S.4    Tennant, M.K.5    Plymate, S.R.6
  • 28
    • 3142669010 scopus 로고    scopus 로고
    • SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 gene
    • Blache P., Van De Wetering M., Duluc I., Domon C., Berta P., Freund J.N., Clevers H., Jay P. SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 gene. J. Cell Biol. 2004, 166:37-47.
    • (2004) J. Cell Biol. , vol.166 , pp. 37-47
    • Blache, P.1    Van De Wetering, M.2    Duluc, I.3    Domon, C.4    Berta, P.5    Freund, J.N.6    Clevers, H.7    Jay, P.8
  • 29
    • 18744374448 scopus 로고    scopus 로고
    • RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition
    • Afonja O., Raaka B.M., Huang A., Das S., Zhao X., Helmer E., Juste D., Samuels H.H. RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition. Oncogene 2002, 51:7850-8760.
    • (2002) Oncogene , vol.51 , pp. 7850-8760
    • Afonja, O.1    Raaka, B.M.2    Huang, A.3    Das, S.4    Zhao, X.5    Helmer, E.6    Juste, D.7    Samuels, H.H.8
  • 31
    • 59149089747 scopus 로고    scopus 로고
    • Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus
    • Topol L., Chen W., Song H., Day T.F., Yang Y. Sox9 inhibits Wnt signaling by promoting beta-catenin phosphorylation in the nucleus. J. Biol. Chem. 2009, 284:3323-3333.
    • (2009) J. Biol. Chem. , vol.284 , pp. 3323-3333
    • Topol, L.1    Chen, W.2    Song, H.3    Day, T.F.4    Yang, Y.5
  • 34
    • 0035503920 scopus 로고    scopus 로고
    • SOX7 transcription factor: sequence, chromosomal localization, expression, transactivation and interference with Wnt signaling
    • Takash W., Canizares J., Bonneaud N., Poulat F., Mattei M.G., Jay P., Berta P. SOX7 transcription factor: sequence, chromosomal localization, expression, transactivation and interference with Wnt signaling. Nucleic Acids Res. 2001, 29:4274-4283.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 4274-4283
    • Takash, W.1    Canizares, J.2    Bonneaud, N.3    Poulat, F.4    Mattei, M.G.5    Jay, P.6    Berta, P.7
  • 35
    • 0033213619 scopus 로고    scopus 로고
    • Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin
    • Zorn A.M., Barish G.D., Williams B.O., Lavender P., Klymkowsky M.W., Varmus H.E. Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin. Mol. Cell 1999, 4:487-498.
    • (1999) Mol. Cell , vol.4 , pp. 487-498
    • Zorn, A.M.1    Barish, G.D.2    Williams, B.O.3    Lavender, P.4    Klymkowsky, M.W.5    Varmus, H.E.6
  • 36
    • 0033105051 scopus 로고    scopus 로고
    • The DNA binding specificity of Sox9 and other Sox proteins
    • Mertin S., McDowall G.S., Harley R.V. The DNA binding specificity of Sox9 and other Sox proteins. Nucleic Acids Res. 1999, 27:1359-1364.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 1359-1364
    • Mertin, S.1    McDowall, G.S.2    Harley, R.V.3
  • 37
    • 0033559518 scopus 로고    scopus 로고
    • From head to toes: the multiple facets of Sox proteins
    • Wegner M. From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res. 1999, 27:1409-1420.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 1409-1420
    • Wegner, M.1
  • 38
    • 35648965654 scopus 로고    scopus 로고
    • Mechanistic insights from structural studies of beta-catenin and its binding partners
    • Xu W., Kimelman D. Mechanistic insights from structural studies of beta-catenin and its binding partners. J. Cell Sci. 2007, 120:3337-3343.
    • (2007) J. Cell Sci. , vol.120 , pp. 3337-3343
    • Xu, W.1    Kimelman, D.2
  • 41
    • 79955608022 scopus 로고    scopus 로고
    • Krüppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion
    • Yu F., Ji L., Chen H., Fu J., Ray S., Huang S., Zheng H., Ai W. Krüppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion. Oncogene 2011, 30:2161-2172.
    • (2011) Oncogene , vol.30 , pp. 2161-2172
    • Yu, F.1    Ji, L.2    Chen, H.3    Fu, J.4    Ray, S.5    Huang, S.6    Zheng, H.7    Ai, W.8
  • 42
    • 30144440248 scopus 로고    scopus 로고
    • The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene
    • Rowland B.D., Bernards R., Peeper D.S. The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat. Cell Biol. 2005, 7:1074-1082.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 1074-1082
    • Rowland, B.D.1    Bernards, R.2    Peeper, D.S.3
  • 43
    • 77649323253 scopus 로고    scopus 로고
    • Krüppel like factor 4 (KLF4): a transcription factor with diverse context-dependent functions
    • Vangapandu H., Ai W. Krüppel like factor 4 (KLF4): a transcription factor with diverse context-dependent functions. Gene Ther. Mol. Biol. 2009, 13:94-104.
    • (2009) Gene Ther. Mol. Biol. , vol.13 , pp. 94-104
    • Vangapandu, H.1    Ai, W.2
  • 45
    • 65249112671 scopus 로고    scopus 로고
    • Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid
    • Passeron T., Valencia J.C., Namiki T., Vieira W.D., Passeron H., Miyamura Y., Hearing V.J. Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid. J. Clin. Invest. 2009, 119:954-963.
    • (2009) J. Clin. Invest. , vol.119 , pp. 954-963
    • Passeron, T.1    Valencia, J.C.2    Namiki, T.3    Vieira, W.D.4    Passeron, H.5    Miyamura, Y.6    Hearing, V.J.7
  • 47
    • 40949145618 scopus 로고    scopus 로고
    • SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion
    • Wang H., Leav I., Ibaragi S., Wegner M., Hu G.F., Lu M.L., Balk S.P., Yuan X. SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion. Cancer Res. 2008, 68:1625-1630.
    • (2008) Cancer Res. , vol.68 , pp. 1625-1630
    • Wang, H.1    Leav, I.2    Ibaragi, S.3    Wegner, M.4    Hu, G.F.5    Lu, M.L.6    Balk, S.P.7    Yuan, X.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.