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Volumn 73, Issue 13, 2013, Pages 3987-3996

Dysregulated expression of FOXM1 isoforms drives progression of pancreatic cancer

Author keywords

[No Author keywords available]

Indexed keywords

FORKHEAD TRANSCRIPTION FACTOR; KRUPPEL LIKE FACTOR 4; MESSENGER RNA; TRANSCRIPTION FACTOR FORKHEAD BOX M1A; TRANSCRIPTION FACTOR FORKHEAD BOX M1B; TRANSCRIPTION FACTOR FORKHEAD BOX M1B1; TRANSCRIPTION FACTOR FORKHEAD BOX M1B2; TRANSCRIPTION FACTOR FORKHEAD BOX M1C; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

EID: 84880056261     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-3859     Document Type: Article
Times cited : (94)

References (45)
  • 2
    • 45749089796 scopus 로고    scopus 로고
    • Metastatic Pancreatic Cancer 2008: Is the glass less empty
    • Nieto J, Grossbard ML, Kozuch P. Metastatic pancreatic cancer 2008: is the glass less empty. Oncologist 2008;13: 562-76.
    • (2008) Oncologist , vol.13 , pp. 562-576
    • Nieto, J.1    Grossbard, M.L.2    Kozuch, P.3
  • 3
    • 68049098322 scopus 로고    scopus 로고
    • Pancreatic cancer: Current and future treatment strategies
    • Pliarchopoulou K, Pectasides D. Pancreatic cancer: current and future treatment strategies. Cancer Treat Rev 2009;35: 431-6.
    • (2009) Cancer Treat Rev , vol.35 , pp. 431-436
    • Pliarchopoulou, K.1    Pectasides, D.2
  • 4
    • 77949264996 scopus 로고    scopus 로고
    • Advanced pancreatic carcinoma: Current treatment and future challenges
    • Stathis A, Moore MJ. Advanced pancreatic carcinoma: current treatment and future challenges. Nat Rev Clin Oncol 2010;7: 163-72.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 163-172
    • Stathis, A.1    Moore, M.J.2
  • 5
    • 0027270989 scopus 로고
    • Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5
    • Clark KL, Halay ED, Lai E, Burley SK. Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 1993;364: 412-20.
    • (1993) Nature , vol.364 , pp. 412-420
    • Clark, K.L.1    Halay, E.D.2    Lai, E.3    Burley, S.K.4
  • 6
    • 79851492288 scopus 로고    scopus 로고
    • Multiple faces of FOXM1 transcription factor: Lessons from transgenic mouse models
    • Kalin TV, Ustiyan V, Kalinichenko VV. Multiple faces of FOXM1 transcription factor: lessons from transgenic mouse models. Cell Cycle 2011;10: 396-405.
    • (2011) Cell Cycle , vol.10 , pp. 396-405
    • Kalin, T.V.1    Ustiyan, V.2    Kalinichenko, V.V.3
  • 7
    • 0031020158 scopus 로고    scopus 로고
    • Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues
    • Ye H, Kelly TF, Samadani U, Lim L, Rubio S, Overdier DG, et al. Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues. Mol Cell Biol 1997;17: 1626-41.
    • (1997) Mol Cell Biol , vol.17 , pp. 1626-1641
    • Ye, H.1    Kelly, T.F.2    Samadani, U.3    Lim, L.4    Rubio, S.5    Overdier, D.G.6
  • 8
    • 0030786320 scopus 로고    scopus 로고
    • The winged-helix transcription factor Trident is expressed in cycling cells
    • Korver W, Roose J, Clevers H. The winged-helix transcription factor Trident is expressed in cycling cells. Nucleic Acids Res 1997;25: 1715-9.
    • (1997) Nucleic Acids Res , vol.25 , pp. 1715-1719
    • Korver, W.1    Roose, J.2    Clevers, H.3
  • 9
    • 79959917607 scopus 로고    scopus 로고
    • FOXM1: A master regulator of tumor metastasis
    • Raychaudhuri P, Park HJ. FOXM1: a master regulator of tumor metastasis. Cancer Res 2011;71: 4329-33.
    • (2011) Cancer Res , vol.71 , pp. 4329-4333
    • Raychaudhuri, P.1    Park, H.J.2
  • 10
    • 81055137232 scopus 로고    scopus 로고
    • FOXM1: From cancer initiation to progression and treatment
    • Koo CY, Muir KW, Lam EW. FOXM1: from cancer initiation to progression and treatment. Biochim Biophys Acta 2012;1819: 28-37.
    • (2012) Biochim Biophys Acta , vol.1819 , pp. 28-37
    • Koo, C.Y.1    Muir, K.W.2    Lam, E.W.3
  • 11
    • 33644542405 scopus 로고    scopus 로고
    • The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer
    • Kim IM, Ackerson T, Ramakrishna S, Tretiakova M, Wang IC, Kalin TV, et al. The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer. Cancer Res 2006;66: 2153-61.
    • (2006) Cancer Res , vol.66 , pp. 2153-2161
    • Kim, I.M.1    Ackerson, T.2    Ramakrishna, S.3    Tretiakova, M.4    Wang, I.C.5    Kalin, T.V.6
  • 12
    • 46849097424 scopus 로고    scopus 로고
    • Over-expression of FOXM1 transcription factor is associated with cervical cancer progression and pathogenesis
    • Chan DW, Yu SY, Chiu PM, Yao KM, Liu VW, Cheung AN, et al. Over-expression of FOXM1 transcription factor is associated with cervical cancer progression and pathogenesis. J Pathol 2008;215: 245-52.
    • (2008) J Pathol , vol.215 , pp. 245-252
    • Chan, D.W.1    Yu, S.Y.2    Chiu, P.M.3    Yao, K.M.4    Liu, V.W.5    Cheung, A.N.6
  • 13
    • 65949124894 scopus 로고    scopus 로고
    • Critical role and regulation of transcription factor FOXM1 in human gastric cancer angiogenesis and progression
    • Li Q, Zhang N, Jia Z, Le X, Dai B, Wei D, et al. Critical role and regulation of transcription factor FOXM1 in human gastric cancer angiogenesis and progression. Cancer Res 2009;69: 3501-9.
    • (2009) Cancer Res , vol.69 , pp. 3501-3509
    • Li, Q.1    Zhang, N.2    Jia, Z.3    Le Dai X, B.4    Wei, D.5
  • 14
    • 33645734725 scopus 로고    scopus 로고
    • FOXM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells
    • Liu M, Dai B, Kang SH, Ban K, Huang FJ, Lang FF, et al. FOXM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells. Cancer Res 2006;66: 3593-602.
    • (2006) Cancer Res , vol.66 , pp. 3593-3602
    • Liu, M.1    Dai, B.2    Kang, S.H.3    Ban, K.4    Huang, F.J.5    Lang, F.F.6
  • 15
    • 80455162327 scopus 로고    scopus 로고
    • Expression of FOXM1 is required for the proliferation of medulloblastoma cells and indicates worse survival of patients
    • Priller M, Poschl J, Abrao L, von Bueren AO, Cho YJ, Rutkowski S, et al. Expression of FOXM1 is required for the proliferation of medulloblastoma cells and indicates worse survival of patients. Clin Cancer Res 2011;17: 6791-801.
    • (2011) Clin Cancer Res , vol.17 , pp. 6791-6801
    • Priller, M.1    Poschl, J.2    Abrao, L.3    Von Bueren, A.O.4    Cho, Y.J.5    Rutkowski, S.6
  • 16
    • 34548588406 scopus 로고    scopus 로고
    • Down-regulation of Forkhead BoxM1transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells
    • Wang Z, Banerjee S, Kong D, Li Y, Sarkar FH. Down-regulation of Forkhead BoxM1transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells. Cancer Res 2007;67: 8293-300.
    • (2007) Cancer Res , vol.67 , pp. 8293-8300
    • Wang, Z.1    Banerjee, S.2    Kong, D.3    Li, Y.4    Sarkar, F.H.5
  • 17
    • 84860390076 scopus 로고    scopus 로고
    • Overexpression of FOXM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells
    • Bao B, Wang Z, Ali S, Kong D, Banerjee S, Ahmad A, et al. Overexpression of FOXM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells. J Cell Biochem 2011;112: 2296-306.
    • (2011) J Cell Biochem , vol.112 , pp. 2296-2306
    • Bao, B.1    Wang, Z.2    Ali, S.3    Kong, D.4    Banerjee, S.5    Ahmad, A.6
  • 18
    • 84863073614 scopus 로고    scopus 로고
    • A novel FOXM1-Caveolin signaling pathway promotes pancreatic cancer invasion and metastasis
    • Huang C, Qiu Z, Wang L, Peng Z, Jia Z, Logsdon CD, et al. A novel FOXM1-Caveolin signaling pathway promotes pancreatic cancer invasion and metastasis. Cancer Res 2012;72: 655-65.
    • (2012) Cancer Res , vol.72 , pp. 655-665
    • Huang, C.1    Qiu, Z.2    Wang, L.3    Peng, Z.4    Jia, Z.5    Logsdon, C.D.6
  • 19
    • 0029829236 scopus 로고    scopus 로고
    • Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest
    • Shields JM, Christy RJ, Yang VW. Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest. J Biol Chem 1996;271: 20009-17.
    • (1996) J Biol Chem , vol.271 , pp. 20009-20017
    • Shields, J.M.1    Christy, R.J.2    Yang, V.W.3
  • 20
    • 34250216304 scopus 로고    scopus 로고
    • The diverse functions of Kruppel-like factors 4 and 5 in epithelial biology and pathobiology
    • McConnell BB, Ghaleb AM, Nandan MO, Yang VW. The diverse functions of Kruppel-like factors 4 and 5 in epithelial biology and pathobiology. Bioessays 2007;29: 549-57.
    • (2007) Bioessays , vol.29 , pp. 549-557
    • McConnell, B.B.1    Ghaleb, A.M.2    Nandan, M.O.3    Yang, V.W.4
  • 21
    • 16844386207 scopus 로고    scopus 로고
    • Drastic down-regulation of Kruppel-like factor 4 expression is critical in human gastric cancer development and progression
    • Wei D, Gong W, Kanai M, Schlunk C, Wang L, Yao JC, et al. Drastic down-regulation of Kruppel-like factor 4 expression is critical in human gastric cancer development and progression. Cancer Res 2005;65: 2746-54.
    • (2005) Cancer Res , vol.65 , pp. 2746-2754
    • Wei, D.1    Gong, W.2    Kanai, M.3    Schlunk, C.4    Wang, L.5    Yao, J.C.6
  • 22
    • 0036340041 scopus 로고    scopus 로고
    • The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon
    • Katz JP, Perreault N, Goldstein BG, Lee CS, Labosky PA, Yang VW, et al. The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development 2002;129: 2619-28.
    • (2002) Development , vol.129 , pp. 2619-2628
    • Katz, J.P.1    Perreault, N.2    Goldstein, B.G.3    Lee, C.S.4    Labosky, P.A.5    Yang, V.W.6
  • 25
    • 0037468567 scopus 로고    scopus 로고
    • A novel model system for studying the double-edged roles of nitric oxide production in pancreatic cancer growth and metastasis
    • Wang B, Wei D, Crum VE, Richardson EL, Xiong HH, Luo Y, et al. A novel model system for studying the double-edged roles of nitric oxide production in pancreatic cancer growth and metastasis. Oncogene 2003;22: 1771-82.
    • (2003) Oncogene , vol.22 , pp. 1771-1782
    • Wang, B.1    Wei, D.2    Crum, V.E.3    Richardson, E.L.4    Xiong, H.H.5    Luo, Y.6
  • 26
    • 0348223971 scopus 로고    scopus 로고
    • Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer
    • Wang L, Wei D, Huang S, Peng Z, Le X, Wu TT, et al. Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer. Clin Cancer Res 2003;9: 6371-80.
    • (2003) Clin Cancer Res , vol.9 , pp. 6371-6380
    • Wang, L.1    Wei, D.2    Huang, S.3    Peng, Z.4    Le Wu X, T.T.5
  • 27
    • 0032447249 scopus 로고    scopus 로고
    • Liver metastases are enhanced in homozygous deletionally mutant ICAM-1 or LFA-1 mice
    • Marvin MR, Southall JC, Trokhan S, DeRosa C, Chabot J. Liver metastases are enhanced in homozygous deletionally mutant ICAM-1 or LFA-1 mice. J Surg Res 1998;80: 143-8.
    • (1998) J Surg Res , vol.80 , pp. 143-148
    • Marvin, M.R.1    Southall, J.C.2    Trokhan, S.3    Derosa, C.4    Chabot, J.5
  • 28
    • 55349089547 scopus 로고    scopus 로고
    • FOXM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells
    • Zhang Y, Zhang N, Dai B, Liu M, Sawaya R, Xie K, et al. FOXM1B transcriptionally regulates vascular endothelial growth factor expression and promotes the angiogenesis and growth of glioma cells. Cancer Res 2008;68: 8733-42.
    • (2008) Cancer Res , vol.68 , pp. 8733-8742
    • Zhang, Y.1    Zhang, N.2    Dai, B.3    Liu, M.4    Sawaya, R.5    Xie, K.6
  • 29
    • 49649101156 scopus 로고    scopus 로고
    • Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells
    • Wei D, Kanai M, Jia Z, Le X, Xie K. Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells. Cancer Res 2008;68: 4631-9.
    • (2008) Cancer Res , vol.68 , pp. 4631-4639
    • Wei, D.1    Kanai, M.2    Jia, Z.3    Le, X.4    Xie, K.5
  • 30
    • 78649710595 scopus 로고    scopus 로고
    • KLF4alpha upregulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer
    • Wei D, Wang L, Kanai M, Jia Z, Le X, Li Q, et al. KLF4alpha upregulation promotes cell cycle progression and reduces survival time of patients with pancreatic cancer. Gastroenterology 2010;139: 2135-45.
    • (2010) Gastroenterology , vol.139 , pp. 2135-2145
    • Wei, D.1    Wang, L.2    Kanai, M.3    Jia, Z.4    Le Li X, Q.5
  • 31
    • 34548558343 scopus 로고    scopus 로고
    • Aberrant FOXM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells
    • Dai B, Kang SH, Gong W, Liu M, Aldape KD, Sawaya R, et al. Aberrant FOXM1B expression increases matrix metalloproteinase-2 transcription and enhances the invasion of glioma cells. Oncogene 2007;26: 6212-9.
    • (2007) Oncogene , vol.26 , pp. 6212-6219
    • Dai, B.1    Kang, S.H.2    Gong, W.3    Liu, M.4    Aldape, K.D.5    Sawaya, R.6
  • 32
    • 36248990364 scopus 로고    scopus 로고
    • FOXM1, a typical proliferation-associated transcription factor
    • Wierstra I, Alves J. FOXM1, a typical proliferation-associated transcription factor. Biol Chem 2007;388: 1257-74.
    • (2007) Biol Chem , vol.388 , pp. 1257-1274
    • Wierstra, I.1    Alves, J.2
  • 35
    • 33746780589 scopus 로고    scopus 로고
    • FOXM1c is activated by cyclin E/Cdk2, cyclin A/Cdk2, and cyclin A/Cdk1, but repressed by GSK-3alpha
    • Wierstra I, Alves J. FOXM1c is activated by cyclin E/Cdk2, cyclin A/Cdk2, and cyclin A/Cdk1, but repressed by GSK-3alpha. Biochem Biophys Res Commun 2006;348: 99-108.
    • (2006) Biochem Biophys Res Commun , vol.348 , pp. 99-108
    • Wierstra, I.1    Alves, J.2
  • 36
    • 80053125475 scopus 로고    scopus 로고
    • The transcription factor FOXM1c is activated by protein kinase CK2, protein kinase A (PKA), c-Src and Raf-1
    • Wierstra I. The transcription factor FOXM1c is activated by protein kinase CK2, protein kinase A (PKA), c-Src and Raf-1. Biochem Biophys Res Commun 2011;413: 230-5.
    • (2011) Biochem Biophys Res Commun , vol.413 , pp. 230-235
    • Wierstra, I.1
  • 37
    • 33749386211 scopus 로고    scopus 로고
    • FOXM1c transactivates the human c-myc promoter directly via the two TATA boxes P1 and P2
    • Wierstra I, Alves J. FOXM1c transactivates the human c-myc promoter directly via the two TATA boxes P1 and P2. FEBS J 2006;273: 4645-67.
    • (2006) FEBS J , vol.273 , pp. 4645-4667
    • Wierstra, I.1    Alves, J.2
  • 38
    • 50249083985 scopus 로고    scopus 로고
    • Anaphasepromoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase
    • Park HJ, Costa RH, Lau LF, Tyner AL, Raychaudhuri P. Anaphasepromoting complex/cyclosome-CDH1-mediated proteolysis of the forkhead box M1 transcription factor is critical for regulated entry into S phase. Mol Cell Biol 2008;28: 5162-71.
    • (2008) Mol Cell Biol , vol.28 , pp. 5162-5171
    • Park, H.J.1    Costa, R.H.2    Lau, L.F.3    Tyner, A.L.4    Raychaudhuri, P.5
  • 39
    • 77950616462 scopus 로고    scopus 로고
    • The c-Rel subunit of nuclear factor-kappaB regulates murine liver inflammation, wound-healing, and hepatocyte proliferation
    • Gieling RG, Elsharkawy AM, Caamaño JH, Cowie DE, Wright MC, Ebrahimkhani MR, et al. The c-Rel subunit of nuclear factor-kappaB regulates murine liver inflammation, wound-healing, and hepatocyte proliferation. Hepatology 2010;51: 922-31.
    • (2010) Hepatology , vol.51 , pp. 922-931
    • Gieling, R.G.1    Elsharkawy, A.M.2    Caamaño, J.H.3    Cowie, D.E.4    Wright, M.C.5    Ebrahimkhani, M.R.6
  • 40
    • 11144353897 scopus 로고    scopus 로고
    • FOXM1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor
    • Kalinichenko VV, Major ML, Wang X, Petrovic V, Kuechle J, Yoder HM, et al. FOXM1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor. Genes Dev 2004;18: 830-50.
    • (2004) Genes Dev , vol.18 , pp. 830-850
    • Kalinichenko, V.V.1    Major, M.L.2    Wang, X.3    Petrovic, V.4    Kuechle, J.5    Yoder, H.M.6
  • 41
    • 51049093989 scopus 로고    scopus 로고
    • Plk1- dependent phosphorylation of FOXM1 regulates a transcriptional programme required for mitotic progression
    • Fu Z, Malureanu L, Huang J, Wang W, Li H, van Deursen JM, et al. Plk1- dependent phosphorylation of FOXM1 regulates a transcriptional programme required for mitotic progression. Nat Cell Biol 2008;10: 1076-82.
    • (2008) Nat Cell Biol , vol.10 , pp. 1076-1082
    • Fu, Z.1    Malureanu, L.2    Huang, J.3    Wang, W.4    Li, H.5    Van Deursen, J.M.6
  • 42
    • 84862798695 scopus 로고    scopus 로고
    • Crosstalk of Sp1 and Stat3 signaling in pancreatic cancer pathogenesis
    • Huang C, Xie K. Crosstalk of Sp1 and Stat3 signaling in pancreatic cancer pathogenesis. Cytokine Growth Factor Rev 2012;23: 25-35.
    • (2012) Cytokine Growth Factor Rev , vol.23 , pp. 25-35
    • Huang, C.1    Xie, K.2
  • 43
    • 79960957703 scopus 로고    scopus 로고
    • Combining betulinic acid and mithramycin a effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesis
    • Gao Y, Jia Z, Kong X, Li Q, Chang DZ, Wei D, et al. Combining betulinic acid and mithramycin a effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesis. Cancer Res 2011;71: 5182-93.
    • (2011) Cancer Res , vol.71 , pp. 5182-5193
    • Gao, Y.1    Jia, Z.2    Kong, X.3    Li, Q.4    Chang, D.Z.5    Wei, D.6
  • 45
    • 33744525493 scopus 로고    scopus 로고
    • Transcriptional anti-angiogenesis therapy of human pancreatic cancer
    • Xie K, Wei D, Huang S. Transcriptional anti-angiogenesis therapy of human pancreatic cancer. Cytokine Growth Factor Rev 2006;17: 147-56.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 147-156
    • Xie, K.1    Wei, D.2    Huang, S.3


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